List of works - Falk Weih

A new RelB-dependent CD117+ CD172a+ murine DC subset preferentially induces Th2 differentiation and supports airway hyperresponses in vivo

scientific article published on 27 February 2018

Accumulation of p100, a precursor of NF-κB2, enhances osteoblastic differentiation in vitro and bone formation in vivo in aly/aly mice.

scientific article

Alternative NF-κB signaling controls peripheral homeostasis and function of regulatory T cells

scientific article published on 07 June 2019

Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β Receptors

scientific article

Artery tertiary lymphoid organs contribute to innate and adaptive immune responses in advanced mouse atherosclerosis

scientific article

Central immune tolerance depends on crosstalk between the classical and alternative NF-κB pathways in medullary thymic epithelial cells ⬇️

scientific article published on 3 April 2017

Constitutive activation of the alternative NF-κB pathway disturbs endochondral ossification

scientific article published on 03 January 2019

Constitutive alternative NF-kappaB signaling promotes marginal zone B-cell development but disrupts the marginal sinus and induces HEV-like structures in the spleen

scientific article published on 9 July 2007

Control of dichotomic innate and adaptive immune responses by artery tertiary lymphoid organs in atherosclerosis.

scientific article published on 06 July 2012

Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues

scientific article

Differential RelA- and RelB-dependent gene transcription in LTbetaR-stimulated mouse embryonic fibroblasts

scientific article

Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development

scientific article published on June 2003

Direct transcriptional regulation of RelB by 1alpha,25-dihydroxyvitamin D3 and its analogs: physiologic and therapeutic implications for dendritic cell function.

scientific article

Distinct roles of lymphotoxin-beta signaling and the homeodomain transcription factor Nkx2.3 in the ontogeny of endothelial compartments in spleen

scientific article published on 21 February 2007

Dual functions of Nbs1 in the repair of DNA breaks and proliferation ensure proper V(D)J recombination and T-cell development.

scientific article

Dysfunctional NF-κB and brain myelin formation

scientific article published on 30 October 2013

Fungal-induced cell cycle impairment, chromosome instability and apoptosis via differential activation of NF-κB.

scientific article

Generation of Aorta Transcript Atlases of Wild-Type and Apolipoprotein E-null Mice by Laser Capture Microdissection-Based mRNA Expression Microarrays.

scientific article published on January 2015

Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1.

scientific article published on 17 July 2015

Hyaluronan fragments induce cytokine and metalloprotease upregulation in human melanoma cells in part by signalling via TLR4.

scientific article published on 21 November 2007

In vivo imaging of optic nerve fiber integrity by contrast-enhanced MRI in mice.

scientific article

Lack of nuclear factor-kappa B2/p100 causes a RelB-dependent block in early B lymphopoiesis

scientific article published on 27 May 2008

Laser-capture microdissection of hyperlipidemic/ApoE⁻/⁻ mouse aorta atherosclerosis

scientific article

Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice

scientific article

Magnetic resonance imaging of the mouse visual pathway for in vivo studies of degeneration and regeneration in the CNS.

scientific article published on 30 July 2011

Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizer-like cells on combined tumor necrosis factor receptor-1/lymphotoxin beta-receptor NF-kappaB signaling

scientific article

NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions

scientific article published on March 2016

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis

scientific journal article

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis

scientific article published on 14 December 2015

NF kappa B controls the balance between Fas and tumor necrosis factor cell death pathways during T cell receptor-induced apoptosis via the expression of its target gene A20.

scientific article published on 16 June 2003

NF-κB Signalling and Lymphoid Tissue Organogenesis

NF-κB controls axonal regeneration and degeneration through cell-specific balance of RelA and p50 in the adult CNS.

scientific article

NF-κB2/p100 deficiency impairs immune responses to T-cell-independent type 2 antigens.

scientific article

Neuronal activation of NF-kappaB contributes to cell death in cerebral ischemia

scientific article

Nuclear factor-kappaB contributes to infarction after permanent focal ischemia

scientific article published on 26 February 2004

Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis

scientific article

Processing of the NF-kappa B2 precursor p100 to p52 is critical for RANKL-induced osteoclast differentiation

scientific article published on 01 May 2010

Protective role of NF-kappaB1 (p50) in experimental pneumococcal meningitis

scientific article published in September 2004

Quantitative dissection and modeling of the NF-κB p100-p105 module reveals interdependent precursor proteolysis

scientific article published on 4 December 2014

RHEB1 insufficiency in aged male mice is associated with stress-induced seizures.

scientific article

Regulation of secondary lymphoid organ development by the nuclear factor-kappaB signal transduction pathway

scientific article

Rel/NF-kappaB family member RelA regulates NK1.1- to NK1.1+ transition as well as IL-15-induced expansion of NKT cells

scientific article

RelA and RelB Transcription Factors in Distinct Thymocyte Populations Control Lymphotoxin-Dependent Interleukin-17 Production in γδ T Cells ⬇️

scientific article published on March 25, 2011

RelB Deficiency in Dendritic Cells Protects from Autoimmune Inflammation Due to Spontaneous Accumulation of Tissue T Regulatory Cells

scientific article published on 02 October 2019

RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF

scientific article

RelB regulates Th17 differentiation in a cell-intrinsic manner

scientific article

RelB+ Steady-State Migratory Dendritic Cells Control the Peripheral Pool of the Natural Foxp3+ Regulatory T Cells

scientific article

RelB-dependent stromal cells promote T-cell leukemogenesis

scientific article

RelB-induced expression of Cot, an MAP3K family member, rescues RANKL-induced osteoclastogenesis in alymphoplasia mice by promoting NF-κB2 processing by IKKα.

scientific article published on 31 January 2014

Role of nuclear factor kappa B in central nervous system regeneration

scientific article published on April 2014

Skin inflammation in RelB(-/-) mice leads to defective immunity and impaired clearance of vaccinia virus.

scientific article published in March 2007

Steady state migratory RelB+ langerin+ dermal dendritic cells mediate peripheral induction of antigen-specific CD4+ CD25+ Foxp3+ regulatory T cells

scientific article

The deubiquitinating enzyme CYLD regulates the differentiation and maturation of thymic medullary epithelial cells

scientific article published on 20 January 2015

The non-canonical NF-kappaB Signaling Pathway Contributes to the Expansion and Lymphomagenesis of CD40-activated B Cells ⬇️

scholarly article

The pivotal role of the alternative NF-kappaB pathway in maintenance of basal bone homeostasis and osteoclastogenesis

scientific article published on April 2010

Towards Dissecting The Complexity of The AP-1 (Activator Protein 1) Family

scientific article published on 01 January 2004

p100 Deficiency is insufficient for full activation of the alternative NF-κB pathway: TNF cooperates with p52-RelB in target gene transcription

scientific article (publication date: 2012)

List of works by Falk Weih

A new RelB-dependent CD117+ CD172a+ murine DC subset preferentially induces Th2 differentiation and supports airway hyperresponses in vivo

Accumulation of p100, a precursor of NF-κB2, enhances osteoblastic differentiation in vitro and bone formation in vivo in aly/aly mice.

Alternative NF-κB signaling controls peripheral homeostasis and function of regulatory T cells

Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β Receptors

Artery tertiary lymphoid organs contribute to innate and adaptive immune responses in advanced mouse atherosclerosis

Central immune tolerance depends on crosstalk between the classical and alternative NF-κB pathways in medullary thymic epithelial cells ⬇️

Constitutive activation of the alternative NF-κB pathway disturbs endochondral ossification

Constitutive alternative NF-kappaB signaling promotes marginal zone B-cell development but disrupts the marginal sinus and induces HEV-like structures in the spleen

Control of dichotomic innate and adaptive immune responses by artery tertiary lymphoid organs in atherosclerosis.

Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues

Differential RelA- and RelB-dependent gene transcription in LTbetaR-stimulated mouse embryonic fibroblasts

Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development

Direct transcriptional regulation of RelB by 1alpha,25-dihydroxyvitamin D3 and its analogs: physiologic and therapeutic implications for dendritic cell function.

Distinct roles of lymphotoxin-beta signaling and the homeodomain transcription factor Nkx2.3 in the ontogeny of endothelial compartments in spleen

Dual functions of Nbs1 in the repair of DNA breaks and proliferation ensure proper V(D)J recombination and T-cell development.

Dysfunctional NF-κB and brain myelin formation

Fungal-induced cell cycle impairment, chromosome instability and apoptosis via differential activation of NF-κB.

Generation of Aorta Transcript Atlases of Wild-Type and Apolipoprotein E-null Mice by Laser Capture Microdissection-Based mRNA Expression Microarrays.

Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1.

Hyaluronan fragments induce cytokine and metalloprotease upregulation in human melanoma cells in part by signalling via TLR4.

In vivo imaging of optic nerve fiber integrity by contrast-enhanced MRI in mice.

Lack of nuclear factor-kappa B2/p100 causes a RelB-dependent block in early B lymphopoiesis

Laser-capture microdissection of hyperlipidemic/ApoE⁻/⁻ mouse aorta atherosclerosis

Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice

Magnetic resonance imaging of the mouse visual pathway for in vivo studies of degeneration and regeneration in the CNS.

Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizer-like cells on combined tumor necrosis factor receptor-1/lymphotoxin beta-receptor NF-kappaB signaling

NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis

NF kappa B controls the balance between Fas and tumor necrosis factor cell death pathways during T cell receptor-induced apoptosis via the expression of its target gene A20.

NF-κB Signalling and Lymphoid Tissue Organogenesis

NF-κB controls axonal regeneration and degeneration through cell-specific balance of RelA and p50 in the adult CNS.

NF-κB2/p100 deficiency impairs immune responses to T-cell-independent type 2 antigens.

Neuronal activation of NF-kappaB contributes to cell death in cerebral ischemia

Nuclear factor-kappaB contributes to infarction after permanent focal ischemia

Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis

Processing of the NF-kappa B2 precursor p100 to p52 is critical for RANKL-induced osteoclast differentiation

Protective role of NF-kappaB1 (p50) in experimental pneumococcal meningitis

Quantitative dissection and modeling of the NF-κB p100-p105 module reveals interdependent precursor proteolysis

RHEB1 insufficiency in aged male mice is associated with stress-induced seizures.

Regulation of secondary lymphoid organ development by the nuclear factor-kappaB signal transduction pathway

Rel/NF-kappaB family member RelA regulates NK1.1- to NK1.1+ transition as well as IL-15-induced expansion of NKT cells

RelA and RelB Transcription Factors in Distinct Thymocyte Populations Control Lymphotoxin-Dependent Interleukin-17 Production in γδ T Cells ⬇️

RelB Deficiency in Dendritic Cells Protects from Autoimmune Inflammation Due to Spontaneous Accumulation of Tissue T Regulatory Cells

RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF

RelB regulates Th17 differentiation in a cell-intrinsic manner

RelB+ Steady-State Migratory Dendritic Cells Control the Peripheral Pool of the Natural Foxp3+ Regulatory T Cells

RelB-dependent stromal cells promote T-cell leukemogenesis

RelB-induced expression of Cot, an MAP3K family member, rescues RANKL-induced osteoclastogenesis in alymphoplasia mice by promoting NF-κB2 processing by IKKα.

Role of nuclear factor kappa B in central nervous system regeneration

Skin inflammation in RelB(-/-) mice leads to defective immunity and impaired clearance of vaccinia virus.

Steady state migratory RelB+ langerin+ dermal dendritic cells mediate peripheral induction of antigen-specific CD4+ CD25+ Foxp3+ regulatory T cells

The deubiquitinating enzyme CYLD regulates the differentiation and maturation of thymic medullary epithelial cells

The non-canonical NF-kappaB Signaling Pathway Contributes to the Expansion and Lymphomagenesis of CD40-activated B Cells ⬇️

The pivotal role of the alternative NF-kappaB pathway in maintenance of basal bone homeostasis and osteoclastogenesis

Towards Dissecting The Complexity of The AP-1 (Activator Protein 1) Family

p100 Deficiency is insufficient for full activation of the alternative NF-κB pathway: TNF cooperates with p52-RelB in target gene transcription