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List of works by Hans-Jürgen Wester

(18)F-Fluoroglucosylation of peptides, exemplified on cyclo(RGDfK).

scientific article

(68)Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer

scientific article published on 21 November 2014

(68)Ga-PSMA ligand PET/CT-based radiotherapy in locally recurrent and recurrent oligometastatic prostate cancer : Early efficacy after primary therapy

scientific article published on 7 June 2016

(68)Ga-Pentixafor-PET/CT for Imaging of Chemokine Receptor 4 Expression in Glioblastoma.

scientific article published on 25 January 2016

177Lu-Labeled Prostate-Specific Membrane Antigen Radioligand Therapy of Metastatic Castration-Resistant Prostate Cancer: Safety and Efficacy

scientific article

18F-FDG PET detects inflammatory infiltrates in spinal cord experimental autoimmune encephalomyelitis lesions.

scientific article

18F-FIBT may expand PET for β-amyloid imaging in neurodegenerative diseases

scientific article published on 17 August 2018

18F-fluoro-ethyl-tyrosine positron emission tomography for grading and estimation of prognosis in patients with intracranial gliomas.

scientific article published on 7 February 2015

18F-labeled galacto and PEGylated RGD dimers for PET imaging of αvβ3 integrin expression

scientific article

18F-labeled sufentanil for PET-imaging of mu-opioid receptors

scientific article published in April 2005

18F-rhPSMA-7 positron emission tomography for the detection of biochemical recurrence of prostate cancer following radical prostatectomy

scientific article published on 13 December 2019

213Bi-Labeled Prostate-Specific Membrane Antigen-Targeting Agents Induce DNA Double-Strand Breaks in Prostate Cancer Xenografts

scientific article published on March 2017

3,4,6-Tri-O-acetyl-2-deoxy-2-[18F]fluoroglucopyranosyl Phenylthiosulfonate: A Thiol-Reactive Agent for the Chemoselective18F-Glycosylation of Peptides

scientific article published on 01 January 2007

68Ga- and 111In-labelled DOTA-RGD peptides for imaging of alphavbeta3 integrin expression

scientific article published on 28 March 2008

68Ga- and 177Lu-Labeled PSMA I&T: Optimization of a PSMA-Targeted Theranostic Concept and First Proof-of-Concept Human Studies

scientific article

68Ga-PSMA I&T PET/CT for assessment of prostate cancer: evaluation of image quality after forced diuresis and delayed imaging

scientific article published on 24 March 2016

68Ga-PSMA I&T PET/CT for primary staging of prostate cancer

scientific article published on 16 September 2019

68Ga-PSMA Ligand PET/CT-based Radiotherapy for Lymph Node Relapse of Prostate Cancer After Primary Therapy Delays Initiation of Systemic Therapy

scientific article published in March 2017

68Ga-PSMA PET/CT Imaging Predicting Intraprostatic Tumor Extent, Extracapsular Extension and Seminal Vesicle Invasion Prior to Radical Prostatectomy in Patients with Prostate Cancer.

scientific article published on 7 March 2017

68Ga-PSMA PET/CT: Joint EANM and SNMMI procedure guideline for prostate cancer imaging: version 1.0.

scientific article published on 10 March 2017

68Ga-Pentixafor PET/CT demonstrating higher CXCR4 density in small cell lung carcinoma than in non-small cell variant

scientific article published on 21 January 2017

68Ga-TRAP-(RGD)3 Hybrid Imaging for the In Vivo Monitoring of αvß3-Integrin Expression as Biomarker of Anti-Angiogenic Therapy Effects in Experimental Breast Cancer

scientific article

99mTechnetium-based Prostate-specific Membrane Antigen-radioguided Surgery in Recurrent Prostate Cancer

scientific article published on 3 April 2018

A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins.

scientific article published on 11 January 2017

A Novel (18)F-Labeled Imidazo[2,1-b]benzothiazole (IBT) for High-Contrast PET Imaging of β-Amyloid Plaques

scientific article published on 19 July 2011

A Practical Guide on the Synthesis of Metal Chelates for Molecular Imaging and Therapy by Means of Click Chemistry

scientific article published on 22 June 2016

A conformationally frozen peptoid boosts CXCR4 affinity and anti-HIV activity

scientific article published on 3 July 2012

A cyclen-based tetraphosphinate chelator for the preparation of radiolabeled tetrameric bioconjugates.

scientific article

A monoreactive bifunctional triazacyclononane phosphinate chelator with high selectivity for gallium-68.

scientific article

A new 18F-labeled myocardial PET tracer: myocardial uptake after permanent and transient coronary occlusion in rats

scientific article

A new class of PentixaFor- and PentixaTher-based theranostic agents with enhanced CXCR4-targeting efficiency

scientific article published on 09 July 2020

A pilot study to evaluate 3'-deoxy-3'-18F-fluorothymidine pet for initial and early response imaging in mantle cell lymphoma

scientific article published on 7 November 2011

A shortcut to high-affinity Ga-68 and Cu-64 radiopharmaceuticals: one-pot click chemistry trimerisation on the TRAP platform

scientific article

An interindividual comparison of O-(2-[18F]fluoroethyl)-L-tyrosine (FET)- and L-[methyl-11C]methionine (MET)-PET in patients with brain gliomas and metastases

scientific article published on 11 May 2011

Anti-Inflammatory Effects on Atherosclerotic Lesions Induced by CXCR4-Directed Endoradiotherapy

scientific article published on 01 July 2018

Application of RGD-containing peptides as imaging probes for alphavbeta3 expression

scientific article published on January 2009

Assessment of alphavbeta3 integrin expression after myocardial infarction by positron emission tomography

scientific article published on 6 February 2008

At the bench: Pre-clinical evidence for multiple functions of CXCR4 in cancer

scientific article published on 26 October 2020

Be spoilt for choice with radiolabelled RGD peptides: Preclinical evaluation of 68Ga-TRAP(RGD)3 ⬇️

scientific article published on September 18, 2012

Benefits of NOPO as chelator in gallium-68 peptides, exemplified by preclinical characterization of (68)Ga-NOPO-c(RGDfK).

scientific article published on 4 April 2014

Beta amyloid in Alzheimer's disease: increased deposition in brain is reflected in reduced concentration in cerebrospinal fluid

scientific article published on 06 March 2009

Biodistribution and pharmacokinetics of the alphavbeta3-selective tracer 18F-galacto-RGD in cancer patients

scientific article published in August 2005

Biodistribution and radiation dosimetry for a probe targeting prostate-specific membrane antigen for imaging and therapy

scientific article published on 16 April 2015

Biodistribution and radiation dosimetry in healthy volunteers of a novel tumour-specific probe for PET/CT imaging: BAY 85-8050.

scientific article published on 23 July 2013

Biodistribution and radiation dosimetry of (68)Ga-PSMA HBED CC-a PSMA specific probe for PET imaging of prostate cancer.

scientific article published on 20 May 2016

Bone-seeking TRAP conjugates: surprising observations and their implications on the development of gallium-68-labeled bisphosphonates.

scientific article published on 30 March 2012

CXCR4 Ligands: The Next Big Hit?

scientific article published in September 2017

CXCR4 is a potential target for diagnostic PET/CT imaging in Barrett's dysplasia and esophageal adenocarcinoma.

scientific article published on 5 December 2017

CXCR4-Directed Imaging in Solid Tumors

scientific article published on 14 August 2019

CXCR4-directed theranostics in oncology and inflammation

article published in 2018

Carbohydrate Derivatives for Use in Drug Design: Cyclicαv-Selective RGD Peptides

article by Elisabeth Lohof et al published 4 August 2000 in Angewandte Chemie

Cationic eluate pretreatment for automated synthesis of [⁶⁸Ga]CPCR4.2.

scientific article published on 09 October 2013

Central poststroke pain and reduced opioid receptor binding within pain processing circuitries: a [11C]diprenorphine PET study

scientific article

Characterization and first human investigation of FIBT, a novel fluorinated Aβ plaque neuroimaging PET radioligand

scientific article published on 8 January 2015

Chemokine Receptor 4 Expression in Primary Sjögren's Syndrome

scientific article published on 01 November 2018

Chemokine receptor - Directed imaging and therapy

scientific article published on 12 September 2017

Chemoselective hydrazone formation between HYNIC-functionalized peptides and 18F-fluorinated aldehydes

scientific article published on 01 February 2006

Chemoselective pre-conjugate radiohalogenation of unprotected mono- and multimeric peptides via oxime formation

Click Chemistry in the Design and Production of Hybrid Tracers

scientific article published on 22 July 2019

Clinical Molecular Imaging of Pulmonary CXCR4 Expression to Predict Outcome of Pirfenidone Treatment in IPF

scientific article published on 18 August 2020

Clinical severity of Alzheimer's disease is associated with PIB uptake in PET.

scientific article

Comparative gallium-68 labeling of TRAP-, NOTA-, and DOTA-peptides: practical consequences for the future of gallium-68-PET ⬇️

scientific article published on June 9, 2012

Comparison of 68 Ga-PSMA ligand PET/CT versus conventional cross-sectional imaging for target volume delineation for metastasis-directed radiotherapy for metachronous lymph node metastases from prostate cancer

scientific article published on 04 January 2019

Comparison of [(11)C]Choline ([(11)C]CHO) and [(18)F]Bombesin (BAY 86-4367) as Imaging Probes for Prostate Cancer in a PC-3 Prostate Cancer Xenograft Model.

scientific article published on 19 October 2015

Comparison of [¹¹C]choline ([¹¹C]CHO) and S(+)-β-methyl-[¹¹C]choline ([¹¹C]SMC) as imaging probes for prostate cancer in a PC-3 prostate cancer xenograft model

scientific article published on April 2015

Comparison of cyclic RGD peptides for αvβ3 integrin detection in a rat model of myocardial infarction

scientific article published on 11 May 2013

Comparison of integrin alphaVbeta3 expression and glucose metabolism in primary and metastatic lesions in cancer patients: a PET study using 18F-galacto-RGD and 18F-FDG.

scientific article published on 12 December 2007

Comparison of radioiodinated TOC, TOCA and Mtr-TOCA: the effect of carbohydration on the pharmacokinetics

scientific article

Comparison of standard and delayed imaging to improve the detection rate of [68Ga]PSMA I&T PET/CT in patients with biochemical recurrence or prostate-specific antigen persistence after primary therapy for prostate cancer

scientific article

Complementary, Selective PET Imaging of Integrin Subtypes α5β1 and αvβ3 Using 68Ga-Aquibeprin and 68Ga-Avebetrin.

scientific article published on 3 December 2015

Consensus on molecular imaging and theranostics in prostate cancer

scientific article published on 01 December 2018

Convenient synthesis of (68)Ga-labeled gadolinium(III) complexes: towards bimodal responsive probes for functional imaging with PET/MRI

scientific article published on 01 September 2013

Copper-64 labelling of triazacyclononane-triphosphinate chelators ⬇️

scientific article published on 08 October 2012

Correction: 18F-FIBT may expand PET for β-amyloid imaging in neurodegenerative diseases

scientific article published on 21 November 2018

Correlation of immunohistopathological expression of somatostatin receptor 2 with standardised uptake values in 68Ga-DOTATOC PET/CT.

scientific article published on 20 September 2008

Dendritic poly-chelator frameworks for multimeric bioconjugation

scientific article published on 13 February 2017

Design, synthesis, and functionalization of dimeric peptides targeting chemokine receptor CXCR4.

scientific article published on 11 October 2011

Detection Efficacy of Hybrid 68Ga-PSMA Ligand PET/CT in Prostate Cancer Patients with Biochemical Recurrence After Primary Radiation Therapy Defined by Phoenix Criteria.

scientific article published on 16 February 2017

Detection rate of PET/CT in patients with biochemical relapse of prostate cancer using [68Ga]PSMA I&T and comparison with published data of [68Ga]PSMA HBED-CC.

scientific article

Development and evaluation of compounds for imaging of beta-amyloid plaque by means of positron emission tomography

scientific article published on March 2008

Development of an improved radioiodinated 2-phenylimidazo[1,2-a]pyridine for non-invasive imaging of amyloid plaques

article

Development of novel 68Ga- and 18F-labeled GnRH-I analogues with high GnRHR-targeting efficiency

scientific article

Diagnostic Efficacy of (68)Gallium-PSMA Positron Emission Tomography Compared to Conventional Imaging for Lymph Node Staging of 130 Consecutive Patients with Intermediate to High Risk Prostate Cancer

scientific article published on 9 December 2015

Diet intervention reduces uptake of αvβ3 integrin-targeted PET tracer 18F-galacto-RGD in mouse atherosclerotic plaques

article by Antti Saraste et al published 20 April 2012 in Journal of Nuclear Cardiology

Dimer formation of GdDO3A-arylsulfonamide complexes causes loss of pH-dependency of relaxivity.

scientific article

Disclosing the CXCR4 expression in lymphoproliferative diseases by targeted molecular imaging

scientific article

Dissecting the target leukocyte subpopulations of clinically relevant inflammation radiopharmaceuticals

scientific article published on 28 October 2019

Dual Targeting of Acute Leukemia and Supporting Niche by CXCR4-Directed Theranostics.

scientific article published in January 2018

Dual-Nuclide Radiopharmaceuticals for Positron Emission Tomography Based Dosimetry in Radiotherapy

scientific article

EANM procedure guidelines for radionuclide therapy with 177Lu-labelled PSMA-ligands (177Lu-PSMA-RLT)

scientific article published on 22 August 2019

Early Experience of Rechallenge 177Lu-PSMA Radioligand Therapy After an Initial Good Response in Patients with Advanced Prostate Cancer

scientific article published on 15 November 2018

Early Response Assessment Using 3'-Deoxy-3'-[18F]Fluorothymidine-Positron Emission Tomography in High-Grade Non-Hodgkin's Lymphoma

scientific article published on 01 June 2007

Effect of Carbohydration on the Theranostic Tracer PSMA I&T

scientific article published on 25 July 2018

Efficient formation of inert Bi-213 chelates by tetraphosphorus acid analogues of DOTA: towards improved alpha-therapeutics

scientific article published on 08 August 2018

Entering the era of molecular-targeted precision surgery in recurrent prostate cancer

scientific article published on 20 December 2018

Equilibrium Thermodynamics, Formation, and Dissociation Kinetics of Trivalent Iron and Gallium Complexes of Triazacyclononane-Triphosphinate (TRAP) Chelators: Unraveling the Foundations of Highly Selective Ga-68 Labeling.

scientific article published on 23 May 2018

Evaluation of 68Ga-Glutamate Carboxypeptidase II Ligand Positron Emission Tomography for Clinical Molecular Imaging of Atherosclerotic Plaque Neovascularization

scientific article published on 8 September 2016

Evaluation of Hybrid 68Ga-PSMA Ligand PET/CT in 248 Patients with Biochemical Recurrence After Radical Prostatectomy

scientific article published on 19 March 2015

Evaluation of a novel (18)F-labeled positron-emission tomography perfusion tracer for the assessment of myocardial infarct size in rats

scientific article published on 26 January 2009

Evaluation of alphavbeta3 integrin-targeted positron emission tomography tracer 18F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice

scientific article published on 13 May 2009

Evaluation of cardiac beta-adrenoreceptors in the isolated perfused rat heart using (S)-11C-CGP12388.

scientific article published in March 2004

Exploring the Role of RGD-Recognizing Integrins in Cancer

scientific article published on 4 September 2017

FIBT versus florbetaben and PiB: a preclinical comparison study with amyloid-PET in transgenic mice

scientific article

Fast and repetitive in-capillary production of [18F]FDG.

scientific article published on 27 November 2008

Feasibility of CXCR4-Directed Radioligand Therapy in Advanced Diffuse Large B-Cell Lymphoma

scientific article published on 18 May 2018

First (18)F-labeled tracer suitable for routine clinical imaging of sst receptor-expressing tumors using positron emission tomography

scientific article published on June 2004

First 18F-Labeled Pentixafor-Based Imaging Agent for PET Imaging of CXCR4 Expression In Vivo

scientific article published on 01 June 2016

First Experience with Chemokine Receptor CXCR4-Targeted PET Imaging of Patients with Solid Cancers

scientific article published on 14 January 2016

Fluorescence guided surgery and tracer-dose, fact or fiction?

scientific article

Focal uptake of 68Ga-DOTATOC in the pancreas: pathological or physiological correlate in patients with neuroendocrine tumours?

scientific article published on 27 July 2011

From a Helix to a Small Cycle: Metadynamics-Inspired αvβ6 Integrin Selective Ligands.

scientific article published on 16 April 2018

Fully Automated 89Zr Labeling and Purification of Antibodies

scientific article published on 07 December 2018

Functional Imaging of Pheochromocytoma with Ga-DOTATOC and C-HED in a Genetically Defined Rat Model of Multiple Endocrine Neoplasia

scientific article published on 8 June 2011

Fusion of a recombinant antibody fragment with a homo-amino-acid polymer: effects on biophysical properties and prolonged plasma half-life

scientific article published on 26 June 2007

GMP production.Shaping the future ⬇️

scientific article published on 01 January 2012

Gluc-Lys([18F]FP)-TOCA PET in patients with SSTR-positive tumors: biodistribution and diagnostic evaluation compared with [111In]DTPA-octreotide.

scientific article

High contrast tumor imaging with radio-labeled antibody Fab fragments tailored for optimized pharmacokinetics via PASylation

scientific article

High opiate receptor binding potential in the human lateral pain system

scientific article published on 7 December 2005

Histologically-confirmed diagnostic efficacy of 18F-rhPSMA-7 positron emission tomography for N-staging of patients with primary high risk prostate cancer

scientific article published on 13 December 2019

How Many PET Tracers Do We Need?

scientific article published on 01 December 2011

How is (68)Ga labeling of macrocyclic chelators influenced by metal ion contaminants in (68)Ge/(68)Ga generator eluates?

scientific article published on 07 November 2012

Hybrid Tracers Based on Cyanine Backbones Targeting Prostate-Specific Membrane Antigen: Tuning Pharmacokinetic Properties and Exploring Dye-Protein Interaction

scientific article published on 03 September 2019

Hypoxia imaging with FAZA-PET and theoretical considerations with regard to dose painting for individualization of radiotherapy in patients with head and neck cancer

scientific article published on October 2007

Hypoxia-specific tumor imaging with 18F-fluoroazomycin arabinoside.

scientific article

Identification of CXCR4 Expression By Targeted PET/MR Imaging in Patients with Acute Myeloid Leukemia (AML) ⬇️

scholarly article

Image-Guided Surgery: Are We Getting the Most Out of Small-Molecule Prostate-Specific-Membrane-Antigen-Targeted Tracers?

scientific article published on 06 January 2020

Imaging Characteristics and First Experience of [68Ga]THP-PSMA, a Novel Probe for Rapid Kit-Based Ga-68 Labeling and PET Imaging: Comparative Analysis with [68Ga]PSMA I&T.

scientific article published on 17 January 2018

Imaging Inflammation in Atherosclerosis with CXCR4-directed 68Ga-Pentixafor PET/CT - Correlation with 18F-FDG PET/CT

scientific article published on 25 October 2019

Imaging bone and soft tissue tumors with the proliferation marker [18F]fluorodeoxythymidine

scientific article published on 29 April 2008

Imaging chemokine receptor CXCR4 in chronic infection of the bone with (68)Ga-Pentixafor-PET/CT - first insights

scientific article published on 20 July 2017

Imaging gastric cancer with PET and the radiotracers 18F-FLT and 18F-FDG: a comparative analysis

scientific article published on 15 November 2007

Imaging of C-X-C Motif Chemokine Receptor CXCR4 Expression After Myocardial Infarction With [68Ga]Pentixafor-PET/CT in Correlation With Cardiac MRI.

scientific article published on 9 February 2018

Imaging of Chemokine Receptor 4 Expression in Neuroendocrine Tumors - a Triple Tracer Comparative Approach

scientific article

Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease

scientific article published on 21 September 2007

Imaging of chemokine receptor CXCR4 expression in culprit and nonculprit coronary atherosclerotic plaque using motion-corrected [Ga]pentixafor PET/CT

scientific article published on 03 July 2018

Imaging of integrin alpha(v)beta(3) expression in patients with malignant glioma by [18F] Galacto-RGD positron emission tomography

scientific article

Imaging of proliferation in hepatocellular carcinoma with the in vivo marker 18F-fluorothymidine

scientific article published on 18 August 2009

Imaging proliferation to monitor early response of lymphoma to cytotoxic treatment

scientific article

Imaging the Cytokine Receptor CXCR4 in Atherosclerotic Plaques with the Radiotracer 68Ga-Pentixafor for PET.

scientific article published on 27 October 2016

Immunohistochemical detection of chemokine receptor 4 expression in chronic osteomyelitis confirms specific uptake in 68Ga-Pentixafor-PET/CT

scientific article published on 28 September 2018

Improvement of pharmacokinetics of radioiodinated Tyr(3)-octreotide by conjugation with carbohydrates

scientific article published in September 2002

In Vivo Characterization of 4 Ga-Labeled Multimeric RGD Peptides to Image αβ Integrin Expression in 2 Human Tumor Xenograft Mouse Models

In Vivo PET Imaging of the Cancer Integrin αvβ6 Using 68Ga-Labeled Cyclic RGD Nonapeptides

scientific article published on 15 December 2016

In human visualization of ibrutinib-induced CLL compartment shift

scientific article published on 24 June 2020

In vivo biokinetic and metabolic characterization of the ⁶⁸Ga-labelled α5β1-selective peptidomimetic FR366.

scientific article published on 24 October 2015

In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma

scientific article

Initial Experience with Volumetric 68Ga-PSMA I&T PET/CT for Assessment of Whole-Body Tumor Burden as a Quantitative Imaging Biomarker in Patients with Prostate Cancer

scientific article published on 18 May 2017

Initial characterization of an 18F-labeled myocardial perfusion tracer

scientific article

Integrating MRI and chemokine receptor CXCR4-targeted PET for detection of leukocyte infiltration in complicated urinary tract infections after kidney transplantation

scientific article

Internalization of sst2, sst3, and sst5 receptors: effects of somatostatin agonists and antagonists.

scientific article published on March 2006

International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature

scientific article published on 01 October 2018

Intraindividual tumor heterogeneity in NET - Further insight by C-X-C motif chemokine receptor 4-directed imaging

scientific article published on 09 November 2016

Intrapatient Comparison of 111In-PSMA I&T SPECT/CT and Hybrid 68Ga-HBED-CC PSMA PET in Patients With Early Recurrent Prostate Cancer.

scientific article published on 6 June 2016

Intratumoral spatial distribution of hypoxia and angiogenesis assessed by 18F-FAZA and 125I-Gluco-RGD autoradiography

scientific article

Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: the potential impact of CXCL12/CXCR4 axis in EGFRmut NSCLC in diagnosis, follow-up and treatment.

scientific article published on 10 April 2018

Ligands for mapping alphavbeta3-integrin expression in vivo.

scientific article published in July 2009

MA-NOTMP: A Triazacyclononane Trimethylphosphinate Based Bifunctional Chelator for Gallium Radiolabelling of Biomolecules.

scientific article

Mapping of the binding interface of PET tracer molecules and Alzheimer Disease Aβ fibrils using MAS solid-state NMR

scientific article published on 15 April 2020

Metabolically stabilized benzothiazoles for imaging of amyloid plaques

scientific article published on 24 February 2007

Modeling and Predicting Tumor Response in Radioligand Therapy

scientific article published on 10 May 2018

Modulation of pharmacokinetics of radioiodinated sugar-conjugated somatostatin analogues by variation of peptide net charge and carbohydration chemistry

scientific article

Molar Activity of Ga-68 Labeled PSMA Inhibitor Conjugates Determines PET Imaging Results

scientific article published on 27 July 2018

Molecular Imaging in Oncology Using Positron Emission Tomography.

scientific article published in March 2018

Molecular Imaging of Early v 3 Integrin Expression Predicts Long-Term Left-Ventricle Remodeling After Myocardial Infarction in Rats

scientific article published on 01 February 2012

Molecular Imaging of the Chemokine Receptor CXCR4 After Acute Myocardial Infarction.

scientific article published on 5 November 2015

Molecular imaging of proliferation and glucose utilization: utility for monitoring response and prognosis after neoadjuvant therapy in locally advanced gastric cancer

scientific article published on 3 May 2011

Molecular imaging of proliferation in vivo: positron emission tomography with [18F]fluorothymidine

scientific article published on 24 March 2009

Molecular imaging targeting peptide receptors

scientific article published on 24 March 2009

Molecular targeting with peptides or peptide-polymer conjugates: just a question of size?

scientific article

Multimodal molecular imaging of integrin αvβ3 for in vivo detection of pancreatic cancer

scientific article published on 18 February 2014

Multiparametric MR and PET Imaging of Intratumoral Biological Heterogeneity in Patients with Metastatic Lung Cancer Using Voxel-by-Voxel Analysis

scientific article

Multiparametric PET and MRI of myocardial damage after myocardial infarction: correlation of integrin αvβ3 expression and myocardial blood flow

scientific article published on 24 September 2020

Myeloablative Anti-CD20 Radioimmunotherapy +/- High-Dose Chemotherapy Followed by Autologous Stem Cell Support for Relapsed/Refractory B-Cell Lymphoma Results in Excellent Long-Term Survival ⬇️

scientific article published on June 1, 2013

Myocardial Kinetics of a Novel [18F]-Labeled Sympathetic Nerve PET Tracer LMI1195 in the Isolated Perfused Rabbit Heart

scientific article published on 18 March 2015

Myocardial infarction triggers cardioprotective antigen-specific T helper cell responses

scientific article published on 13 August 2019

N-Methylation of isoDGR Peptides: Discovery of a Selective α5β1-Integrin Ligand as a Potent Tumor Imaging Agent

scientific article published on 06 March 2018

N-terminal sugar conjugation and C-terminal Thr-for-Thr(ol) exchange in radioiodinated Tyr3-octreotide: effect on cellular ligand trafficking in vitro and tumor accumulation in vivo

scientific article

Non-invasive assessment of inter-and intrapatient variability of integrin expression in metastasized prostate cancer by PET.

scientific article published on 6 April 2016

Non-invasive imaging of glycoprotein VI binding to injured arterial lesions

scientific article published on 01 May 2005

Noninvasive visualization of the activated alphavbeta3 integrin in cancer patients by positron emission tomography and [18F]Galacto-RGD

scientific article

Nuclear imaging probes: from bench to bedside

scientific article published on June 2007

Nuclear medicine 2013: from status quo to status go.

scientific article published on 3 October 2013

O-(2-[(18)F]Fluoroethyl)- L-tyrosine (FET): a tracer for differentiation of tumour from inflammation in murine lymph nodes

scientific article published on 28 May 2002

One-step ¹⁸F-labeling of carbohydrate-conjugated octreotate-derivatives containing a silicon-fluoride-acceptor (SiFA): in vitro and in vivo evaluation as tumor imaging agents for positron emission tomography (PET).

scientific article published on 17 November 2010

Opioidergic activation in the medial pain system after heat pain

scientific article published on 9 March 2006

Orthogonally protected artificial amino acid as tripod ligand for automated peptide synthesis and labeling with [(99m)Tc(OH(2))(3)(CO)(3)](+).

scientific article published on 26 December 2012

Oxalic Acid Supported Si–18F-Radiofluorination: One-Step Radiosynthesis of N-Succinimidyl 3-(Di-tert-butyl[18F]fluorosilyl)benzoate ([18F]SiFB) for Protein Labeling ⬇️

scientific article published on January 5, 2012

PET Imaging of Integrin αVβ3 Expression ⬇️

scientific article published on January 17, 2011

PET imaging of CXCR4 receptors in cancer by a new optimized ligand

scientific article

PET imaging of chemokine receptor CXCR4 in patients with primary and recurrent breast carcinoma

scientific article published on 06 September 2018

PET of CXCR4 expression by a (68)Ga-labeled highly specific targeted contrast agent

scientific article published in November 2011

PET-based human dosimetry of 18F-galacto-RGD, a new radiotracer for imaging alpha v beta3 expression.

scientific article

PET/CT imaging of integrin αvβ3 expression in human carotid atherosclerosis

scientific article published on 8 January 2014

PSMA Theranostics Using PET and Subsequent Radioguided Surgery in Recurrent Prostate Cancer

scientific article published on 27 May 2016

PSMA-Targeted Radiopharmaceuticals for Imaging and Therapy

scientific article published on 30 April 2019

Patterns of Progression After 68Ga-PSMA-Ligand PET/CT-Guided Radiation Therapy for Recurrent Prostate Cancer

scientific article published on 07 September 2018

Patterns of alphavbeta3 expression in primary and metastatic human breast cancer as shown by 18F-Galacto-RGD PET.

scientific article

Patterns of relapse as determined by (68)Ga-PSMA ligand PET/CT after radical prostatectomy : Importance for tailoring and individualizing treatment.

scientific article

Peptide-Receptor Radiotherapy with CXCR4-Targeting Pentixather Reduces Leukemia Burden in Acute Leukemia PDX and Patients ⬇️

scholarly article

Perspective of αvβ6-Integrin Imaging for Clinical Management of Pancreatic Carcinoma and Its Precursor Lesions

scientific article

Phenotyping of tumor biology in patients by multimodality multiparametric imaging: relationship of microcirculation, alphavbeta3 expression, and glucose metabolism

scientific article

Phosphinic acid functionalized polyazacycloalkane chelators for radiodiagnostics and radiotherapeutics: unique characteristics and applications

scientific article published on 03 April 2014

Positron emission tomography as a tool for translational research in oncology

scientific article published in July 2004

Positron emission tomography using [18F]Galacto-RGD identifies the level of integrin alpha(v)beta3 expression in man.

scientific article published in July 2006

Positron emission tomography/magnetic resonance imaging with 68Gallium-labeled ligand of prostate-specific membrane antigen: promising novel option in prostate cancer imaging?

scientific article published on 21 July 2014

Potential influence of concomitant chemotherapy on CXCR4 expression in receptor directed endoradiotherapy

scientific article

Preclinical Evaluation and First Patient Application of 99mTc-PSMA-I&S for SPECT Imaging and Radioguided Surgery in Prostate Cancer

scientific article

Preclinical comparison of four [<sup>18</sup>F, <sup>nat</sup>Ga]rhPSMA-7 isomers: influence of the stereoconfiguration on pharmacokinetics

scientific article published on 07 December 2020

Preclinical evaluation of [(68)Ga]NOTA-pentixafor for PET imaging of CXCR4 expression in vivo - a comparison to [(68)Ga]pentixafor.

scientific article published on 21 September 2016

Predictive value of initial 18F-FLT uptake in patients with aggressive non-Hodgkin lymphoma receiving R-CHOP treatment

scientific article published on 15 April 2011

Preferred transport of O-(2-[18F]fluoroethyl)-D-tyrosine (D-FET) into the porcine brain.

scientific article published on 9 February 2007

Proof of principle for the use of 11C-labelled peptides in tumour diagnosis with PET.

scientific article

Prostate-Specific Membrane Antigen-Guided Surgery

scientific article published on 15 November 2019

Prostate-specific membrane antigen-radioguided surgery for metastatic lymph nodes in prostate cancer

scientific article published on 6 May 2015

Protein expression profiling in esophageal adenocarcinoma patients indicates association of heat-shock protein 27 expression and chemotherapy response

scientific article published in December 2008

Prototypic 18F-Labeled Argininamide-Type Neuropeptide Y Y1R Antagonists as Tracers for PET Imaging of Mammary Carcinoma.

scientific article published on 21 February 2017

Quantitative and Qualitative Analyses of Biodistribution and PET Image Quality of Novel Radiohybrid PSMA, 18F- rhPSMA-7, in Patients with Prostate Cancer

scientific article published on 13 December 2019

Quantitative longitudinal interrelationships between brain metabolism and amyloid deposition during a 2-year follow-up in patients with early Alzheimer's disease

scientific article published on 28 August 2012

Radiohybrid ligands: a novel tracer concept exemplified by 18F- or 68Ga-labeled rhPSMA-inhibitors

scientific article published on 20 December 2019

Radiolabeled carbohydrated somatostatin analogs: a review of the current status

scientific article published on April 2004

Radiolabeled tracers for imaging of tumor angiogenesis and evaluation of anti-angiogenic therapies

scientific article

Radiosynthesis and pre-clinical evaluation of [68Ga] labeled antimicrobial peptide fragment GF-17 as a potential infection imaging PET radiotracer

scientific article published on 10 April 2019

Rapid and high-yield solution-phase synthesis of DOTA-Tyr3-octreotide and DOTA-Tyr3-octreotate using unprotected DOTA

Re-thinking the role of radiometal isotopes: Towards a future concept for theranostic radiopharmaceuticals.

scientific article published on 16 November 2017

Regional Expansion of Hypometabolism in Alzheimer's Disease Follows Amyloid Deposition with Temporal Delay ⬇️

scientific article published on June 15, 2011

Response assessment with the CXCR4-directed positron emission tomography tracer [68Ga]Pentixafor in a patient with extranodal marginal zone lymphoma of the orbital cavities

scientific article

Seeing the unseen: post-infarction inflammation in an isolated right ventricular myocardial infarction visualized by combined cardiac magnetic resonance imaging and chemokine receptor CXCR4-targeted molecular imaging

scientific article published on 01 March 2018

Selective Targeting of Integrin αvβ8 by a Highly Active Cyclic Peptide

scientific article published on 06 February 2019

Selective imaging of the angiogenic relevant integrins α5β1 and αvβ3.

scientific article

Side Effects of CXC-Chemokine Receptor 4-Directed Endoradiotherapy with Pentixather Before Hematopoietic Stem Cell Transplantation

scientific article published on 08 March 2019

Simultaneous (68)Ga-PSMA HBED-CC PET/MRI Improves the Localization of Primary Prostate Cancer.

scientific article published on 18 January 2016

Single Lesion on Prostate-specific Membrane Antigen-ligand Positron Emission Tomography and Low Prostate-specific Antigen Are Prognostic Factors for a Favorable Biochemical Response to Prostate-specific Membrane Antigen-targeted Radioguided Surgery

scientific article published on 12 April 2019

Small-animal PET imaging of amyloid-beta plaques with [11C]PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease

scientific article

Specific and high-level targeting of radiolabeled octreotide analogues to human medulloblastoma xenografts ⬇️

scientific article published on May 1, 2003

Syntheses, biological evaluation, and molecular modeling of 18F-labeled 4-anilidopiperidines as mu-opioid receptor imaging agents

scientific article published in December 2005

Synthesis and Preclinical Characterization of the PSMA-Targeted Hybrid Tracer PSMA-I&F for Nuclear and Fluorescence Imaging of Prostate Cancer

Synthesis and evaluation of 11C-labeled imidazo[2,1-b]benzothiazoles (IBTs) as PET tracers for imaging β-amyloid plaques in Alzheimer's disease

scientific article published on 28 January 2011

Synthesis and evaluation of a full-agonist orvinol for PET-imaging of opioid receptors: [11C]PEO.

scientific article

Synthesis and in vitro and in vivo evaluation of urea-based PSMA inhibitors with increased lipophilicity

scientific article published on 22 August 2018

Synthesis and preclinical evaluation of DOTAGA-conjugated PSMA ligands for functional imaging and endoradiotherapy of prostate cancer

scientific article published on 25 November 2014

Synthesis and preclinical evaluation of novel 18F-labeled Glu-urea-Glu-based PSMA inhibitors for prostate cancer imaging: a comparison with 18F-DCFPyl and 18F-PSMA-1007.

scientific article published on 12 April 2018

Synthesis of Symmetrical Tetrameric Conjugates of the Radiolanthanide Chelator DOTPI for Application in Endoradiotherapy by Means of Click Chemistry.

scientific article published on 10 April 2018

Synthesis of [18F]fluoroalkyl esters of carfentanil

Synthesis of a [18F]fluorobenzothiazole as potential amyloid imaging agent

Synthesis of novel 1,4,7,10-tetraazacyclodecane-1,4,7,10-tetraacetic acid (DOTA) derivatives for chemoselective attachment to unprotected polyfunctionalized compounds

scientific article

Systemic Radioligand Therapy with (177)Lu Labeled Prostate Specific Membrane Antigen Ligand for Imaging and Therapy in Patients with Metastatic Castration Resistant Prostate Cancer

scientific article published on 7 March 2016

TRAP, a powerful and versatile framework for gallium-68 radiopharmaceuticals

scientific article published on 06 December 2011

Tailored Gallium(III) chelator NOPO: synthesis, characterization, bioconjugation, and application in preclinical Ga-68-PET imaging.

scientific article

Tailoring Fluorescent Dyes To Optimize a Hybrid RGD-Tracer.

scientific article published on 13 April 2016

Targeted positron emission tomography imaging of CXCR4 expression in patients with acute myeloid leukemia

scientific article published on 12 May 2016

Targeting Chemokine Receptor CXCR4 and Translocator Protein for Characterization of High-Risk Plaque in Carotid Stenosis Ex Vivo

scientific article published on 01 August 2018

Textural analysis of pre-therapeutic [18F]-FET-PET and its correlation with tumor grade and patient survival in high-grade gliomas

scientific article

The effect of ligand amount, affinity and internalization on PSMA-targeted imaging and therapy: A simulation study using a PBPK model

scientific article published on 27 December 2019

The future of industrial robot business: Product or performance based?

scholarly article

The gross picture: intraindividual tumour heterogeneity in a patient with nonsecretory multiple myeloma

scientific article published on 25 February 2017

The influence of different metal-chelate conjugates of pentixafor on the CXCR4 affinity

scientific article published on 26 April 2016

The influence of the combination of carboxylate and phosphinate pendant arms in 1,4,7-triazacyclononane-based chelators on their 68Ga labelling properties

scientific article published on 21 July 2015

Theranostic Value of Multimers: Lessons Learned from Trimerization of Neurotensin Receptor Ligands and Other Targeting Vectors

scientific article published on 10 March 2017

Therapeutic Radiopharmaceuticals Targeting Integrin αvβ6

scientific article published on 01 February 2018

Towards NR2B receptor selective imaging agents for PET-synthesis and evaluation of N-[11C]-(2-methoxy)benzyl (E)-styrene-, 2-naphthyl- and 4-trifluoromethoxyphenylamidine.

scientific article published on 13 June 2006

Towards Personalized Treatment of Prostate Cancer: PSMA I&T, a Promising Prostate-Specific Membrane Antigen-Targeted Theranostic Agent

scientific article published on 12 April 2016

Treatment Outcome, Toxicity, and Predictive Factors for Radioligand Therapy with 177Lu-PSMA-I&T in Metastatic Castration-resistant Prostate Cancer

scientific article published on 22 November 2018

Trending: Radioactive and Fluorescent Bimodal/Hybrid Tracers as Multiplexing Solutions for Surgical Guidance

scientific article published on 11 November 2019

Tumor Uptake of Anti-CD20 Fabs Depends on Tumor Perfusion

scientific article published on 14 July 2016

Twins in spirit - episode I: comparative preclinical evaluation of [(68)Ga]DOTATATE and [(68)Ga]HA-DOTATATE

scientific article

Twins in spirit part II: DOTATATE and high-affinity DOTATATE--the clinical experience

scientific article published on 15 February 2014

Twins in spirit part IV - [177Lu] high affinity DOTATATE. A promising new tracer for peptide receptor radiotherapy?

scientific article published on 31 January 2017

Twins in spirit: DOTATATE and high-affinity DOTATATE.

scientific article published on 21 August 2013

Two-step methodology for high-yield routine radiohalogenation of peptides: (18)F-labeled RGD and octreotide analogs

scientific article

Validation of [125I]CPCR4.3 as an investigative tool for the sensitive and specific detection of hCXCR4 and mCXCR4 expression in vitro and in vivo

scientific article published on 13 August 2019

Value of 111 In-prostate-specific membrane antigen (PSMA)-radioguided surgery for salvage lymphadenectomy in recurrent prostate cancer: correlation with histopathology and clinical follow-up.

scientific article published on 10 November 2016

Value of 11C-choline PET and PET/CT in patients with suspected prostate cancer

scientific article

Variation of Specific Activities of 68Ga-Aquibeprin and 68Ga-Avebetrin Enables Selective PET Imaging of Different Expression Levels of Integrins α5β1 and αvβ3.

scientific article published on 5 May 2016

Visualization of Posttraumatic Splenosis on Chemokine Receptor CXCR4-Targeted PET/CT.

scientific article published on 13 February 2017

Volumetric Analysis of F-18-FET-PET Imaging for Brain Metastases

scientific article published on 5 August 2015

Von einer Helix zu einem kleinen Ring: Metadynamik-inspirierte, selektive Liganden für αvβ6-Integrin

Week one FLT-PET response predicts complete remission to R-CHOP and survival in DLBCL

scientific article

[(11)C]Choline positron emission tomography/computed tomography for staging and restaging of patients with advanced prostate cancer

scientific article

[(111)In]DOTATOC as a dosimetric substitute for kidney dosimetry during [(90)Y]DOTATOC therapy: results and evaluation of a combined gamma camera/probe approach

scientific article

[(111)In]PSMA-I&T: expanding the spectrum of PSMA-I&T applications towards SPECT and radioguided surgery

scientific article

[(68)Ga]Pentixafor-PET/CT for Imaging of Chemokine Receptor 4 Expression After Myocardial Infarction

scientific article published in December 2015

[11C]Choline as pharmacodynamic marker for therapy response assessment in a prostate cancer xenograft model

scientific article

[177Lu]pentixather: Comprehensive Preclinical Characterization of a First CXCR4-directed Endoradiotherapeutic Agent.

scientific article published on 11 June 2017

[18F]FLT is superior to [18F]FDG for predicting early response to antiproliferative treatment in high-grade lymphoma in a dose-dependent manner

scientific article published on 05 October 2012

[18F]Galacto-RGD: synthesis, radiolabeling, metabolic stability, and radiation dose estimates

scientific article

[18F]galacto-RGD positron emission tomography for imaging of alphavbeta3 expression on the neovasculature in patients with squamous cell carcinoma of the head and neck

scientific article published in November 2007

[68Ga]-NODAGA-RGD Positron Emission Tomography (PET) for Assessment of Post Myocardial Infarction Angiogenesis as a Predictor for Left Ventricular Remodeling in Mice after Cardiac Stem Cell Therapy

scientific article published on 30 May 2020

[68Ga]-Pentixafor PET/CT for CXCR4-Mediated Imaging of Vestibular Schwannomas

scientific article published on 12 June 2019

[68Ga]Pentixafor PET/MR imaging of chemokine receptor 4 expression in the human carotid artery

scientific article published on 19 April 2019

[68Ga]Pentixafor-PET/CT for imaging of chemokine receptor 4 expression in small cell lung cancer--initial experience

scientific article published on 28 January 2016

[68Ga]Pentixafor-PET/CT for imaging of chemokine receptor CXCR4 expression in multiple myeloma - Comparison to [18F]FDG and laboratory values

scientific article published on January 2017

[68Ga]Pentixafor-PET/MRI for the detection of Chemokine receptor 4 expression in atherosclerotic plaques.

scientific article published on 21 September 2017

[68Ga]Pentixafor-Positron Emission Tomography/Computed Tomography Detects Chemokine Receptor CXCR4 Expression After Ischemic Stroke

scientific article published on 01 September 2016

[68Ga]pentixafor for CXCR4 imaging in a PC-3 prostate cancer xenograft model - comparison with [18F]FDG PET/CT, MRI and ex vivo receptor expression

scientific article published on 16 September 2017

[<sup>68</sup>Ga]Ga-Pentixafor for PET Imaging of Vascular Expression of CXCR-4 as a Marker of Arterial Inflammation in HIV-Infected Patients: A Comparison with <sup>18</sup>F[FDG] PET Imaging

scientific article published on 03 December 2020

[Cu]NOTA-pentixather enables high resolution PET imaging of CXCR4 expression in a preclinical lymphoma model

scientific article published on 19 January 2017

⁸⁹Zr-Labeled Versus ¹²⁴I-Labeled αHER2 Fab with Optimized Plasma Half-Life for High-Contrast Tumor Imaging In Vivo

scientific article

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