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List of works by Jean-Pierre Pelletier

A consensus statement on the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) algorithm for the management of knee osteoarthritis-From evidence-based medicine to the real-life setting

scientific article

A fully automated human knee 3D MRI bone segmentation using the ray casting technique ⬇️

scientific article published on October 29, 2011

A novel negative regulatory element in the human collagenase-3 proximal promoter region

scientific article

A reference case for economic evaluations in osteoarthritis: an expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)

scientific article

ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis

scientific article

Abnormal insulin-like growth factor 1 signaling in human osteoarthritic subchondral bone osteoblasts

scientific article published on January 2006

Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1.

scientific article published on 15 March 2004

Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study

scientific article published on January 2007

Activation of the receptor EphB4 by its specific ligand ephrin B2 in human osteoarthritic subchondral bone osteoblasts.

scientific article

Alteration of Wnt5a expression and of the non-canonical Wnt/PCP and Wnt/PKC-Ca2+ pathways in human osteoarthritis osteoblasts

scientific article

Altered mineralization of human osteoarthritic osteoblasts is attributable to abnormal type I collagen production

scientific article published on May 2009

An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: a report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).

scientific article

An open-label pilot study evaluating by magnetic resonance imaging the potential for a disease-modifying effect of celecoxib compared to a modelized historical control cohort in the treatment of knee osteoarthritis

scientific article

Analgesic efficacy of an oral transmucosal spray formulation of meloxicam alone or in combination with tramadol in cats with naturally occurring osteoarthritis

scientific article

Analgesic efficacy of tramadol in cats with naturally occurring osteoarthritis

scientific article

Analysis of the precision and sensitivity to change of different approaches to assess cartilage loss by quantitative MRI in a longitudinal multicentre clinical trial in patients with knee osteoarthritis

scientific article

Association between hip and knee cartilage measured using radiographs and magnetic resonance imaging: the Tasmanian Older Adult Cohort Study

scientific article published on 30 July 2013

Association between meniscal tears and the peak external knee adduction moment and foot rotation during level walking in postmenopausal women without knee osteoarthritis: a cross-sectional study

scientific article published on 20 May 2008

Association between sensitisation and pain-related behaviours in an experimental canine model of osteoarthritis

scientific article published on 27 July 2014

Association of cartilage-specific deletion of peroxisome proliferator-activated receptor γ with abnormal endochondral ossification and impaired cartilage growth and development in a murine model

scientific article

Automatic human knee cartilage segmentation from 3D magnetic resonance images

scientific article published on 15 July 2010

Biologics and the cardiovascular system: a double-edged sword

scientific article published on January 2013

Bone curvature changes can predict the impact of treatment on cartilage volume loss in knee osteoarthritis: data from a 2-year clinical trial

scientific article

Bone marrow lesions in people with knee osteoarthritis predict progression of disease and joint replacement: a longitudinal study

scientific article published on 7 September 2010

Bone marrow lesions predict site-specific cartilage defect development and volume loss: a prospective study in older adults

scientific article

Brachystemma calycinum D. Don Effectively Reduces the Locomotor Disability in Dogs with Naturally Occurring Osteoarthritis: A Randomized Placebo-Controlled Trial

scientific article

Cardiovascular adverse effects of anti-inflammatory drugs

scientific article published on January 2013

Cartilage in normal and osteoarthritis conditions

scientific article published on April 2008

Cartilage-specific deletion of ephrin-B2 in mice results in early developmental defects and an osteoarthritis-like phenotype during aging in vivo

scientific article

Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis.

scientific article published on 20 March 2014

Cartilage-specific deletion of prar-gamma in mice results in early endochondral ossification defects and accelerated aging-dependent development of osteoarthritis

scientific article published on 9 February 2012

Cellular Aging, Senescence and Autophagy Processes in Osteoarthritis

scientific article published on 27 July 2015

Change in knee structure and change in tibiofemoral joint space width: a five year longitudinal population-based study

scientific article published on 14 January 2016

Characterization of opticin digestion by proteases involved in osteoarthritis development

scientific article published on 8 July 2013

Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study

scientific article

Chondroitin sulfate efficacy versus celecoxib on knee osteoarthritis structural changes using magnetic resonance imaging: a 2-year multicentre exploratory study

scientific article

Chondroitin sulphate for symptomatic osteoarthritis: critical appraisal of meta-analyses

scientific article published on 15 April 2008

Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI

scientific article

Clinical diagnosis of partial or complete anterior cruciate ligament tears using patients' history elements and physical examination tests.

scientific article published on 12 June 2018

Clinical validity of outcome pain measures in naturally occurring canine osteoarthritis

scientific article

Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

scientific article

Comments on the discordant recommendations for the use of symptomatic slow-acting drugs in knee osteoarthritis

scientific article published on 24 March 2015

Computer-aided method for quantification of cartilage thickness and volume changes using MRI: validation study using a synthetic model

scientific article published in August 2003

Concurrent validity of different functional and neuroproteomic pain assessment methods in the rat osteoarthritis monosodium iodoacetate (MIA) model

scientific article

Contribution of H3K4 methylation by SET‐1A to interleukin‐1–induced cyclooxygenase 2 and inducible nitric oxide synthase expression in human osteoarthritis chondrocytes ⬇️

scientific article published on January 1, 2011

Correction: Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease 13 - identification of a new biglycan cleavage site

scientific article published on 5 March 2013

Correlation Between Changes in Global Knee Structures Assessed by Magnetic Resonance Imaging and Radiographic Osteoarthritis Changes Over Ten Years in a Midlife Cohort

scientific article

Corrigendum: ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis

scientific article published in December 2017

Coxofemoral joint kinematics using video fluoroscopic images of treadmill-walking cats: development of a technique to assess osteoarthritis-associated disability

scientific article published on 6 June 2014

Cyclooxygenase-2 and prostaglandins in articular tissues

scientific article published on December 2003

DMOAD developments: present and future

scientific article published on January 2007

Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease-13: identification of a new biglycan cleavage site

scientific article

Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling

scientific article published on 25 June 2008

Diacerein-containing products: same risk of diarrhoea?

scientific article published on 21 February 2018

Diacerein: Benefits, Risks and Place in the Management of Osteoarthritis. An Opinion-Based Report from the ESCEO

scientific article

Diagnostic Validity of Combining History Elements and Physical Examination Tests for Traumatic and Degenerative Symptomatic Meniscal Tears

scientific article published on 27 October 2017

Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts

scientific article

Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: influence of osteotropic factors

scientific article published on 26 April 2008

Discrepancies in composition and biological effects of different formulations of chondroitin sulfate.

scientific article

Disease-modifying effect of strontium ranelate in a subset of patients from the Phase III knee osteoarthritis study SEKOIA using quantitative MRI: reduction in bone marrow lesions protects against cartilage loss

scientific article published on 2 December 2013

Does a placebo effect really occur in dogs afflicted by hip osteoarthritis as measured by force platform gait analysis?

scientific article

Does cartilage volume measurement or radiographic osteoarthritis at baseline independently predict ten-year cartilage volume loss?

scientific article published on 2 February 2016

Effects of diacerein at the molecular level in the osteoarthritis disease process ⬇️

scientific article published on April 1, 2010

Efficacy and safety of oral NSAIDs and analgesics in the management of osteoarthritis: Evidence from real-life setting trials and surveys

scientific article published on 2 December 2015

Efficacy and safety of topical NSAIDs in the management of osteoarthritis: Evidence from real-life setting trials and surveys

scientific article published on 2 December 2015

Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor γ expression in human osteoarthritic chondrocytes ⬇️

scientific article published on March 28, 2012

Egr-1 mediates the suppressive effect of IL-1 on PPARg expression in human OA chondrocytes

scientific article published on 9 February 2012

Egr-1 mediates the suppressive effect of IL-1 on PPARγ expression in human OA chondrocytes

scientific article published on 28 November 2012

Endothelin 1 promotes osteoarthritic cartilage degradation via matrix metalloprotease 1 and matrix metalloprotease 13 induction.

scientific article

Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production

scientific article

Evaluation of osteoarthritis in cats: novel information from a pilot study

scientific article

Evoked temporal summation in cats to highlight central sensitization related to osteoarthritis-associated chronic pain: a preliminary study

scientific article

Exacerbation of Aging-Associated and Instability-Induced Murine Osteoarthritis With Deletion of D Prostanoid Receptor 1, a Prostaglandin D2 Receptor

scientific article published on 23 May 2017

Exploring determinants predicting response to intra-articular hyaluronic acid treatment in symptomatic knee osteoarthritis: 9-year follow-up data from the Osteoarthritis Initiative.

scientific article

Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes.

scientific article published in May 2005

Expression of PPARα, β, and γ in the Hartley guinea pig model of primary osteoarthritis.

scientific article published on 28 November 2012

Expression of peroxisome proliferator-activated receptors α, β, γ, and H- and L-prostaglandin D synthase during osteoarthritis in the spontaneous hartley guinea pig and experimental dog models

scientific article published in April 2013

Extracellular localization of galectin-3 has a deleterious role in joint tissues

scientific article published on January 2007

First-line analysis of the effects of treatment on progression of structural changes in knee osteoarthritis over 24 months: data from the osteoarthritis initiative progression cohort

scientific article

Fully automated system for the quantification of human osteoarthritic knee joint effusion volume using magnetic resonance imaging ⬇️

scientific article published on September 16, 2010

Future therapeutics for osteoarthritis

scientific article published on 17 October 2011

Glucosamine Sulfate Reduces Prostaglandin E2Production in Osteoarthritic Chondrocytes Through Inhibition of Microsomal PGE Synthase-1 ⬇️

scientific article published on November 15, 2011

Glucosamine and osteoarthritis. Effect size is encouraging

scientific article published on 9 November 2010

Health economics in the field of osteoarthritis: an expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).

scientific article published on 29 August 2013

Hepatocyte growth factor induction of collagenase 3 production in human osteoarthritic cartilage: Involvement of the stress-activated protein kinase/c-Jun N-terminal kinase pathway and a sensitive p38 mitogen-activated protein kinase inhibitor cascad

scientific article published on 01 January 2001

High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1β in osteoarthritic synoviocytes

scientific article

History of knee injury and MRI-assessed knee structures in middle- and older-aged adults: a cross-sectional study

scientific article published on 14 August 2014

How Do MRI-Detected Subchondral Bone Marrow Lesions (BMLs) on Two Different MRI Sequences Correlate with Clinically Important Outcomes?

scientific article published on 13 February 2018

How to define responders in osteoarthritis

scientific article published on 17 April 2013

Human adult chondrocytes express hepatocyte growth factor (HGF) isoforms but not HgF: potential implication of osteoblasts on the presence of HGF in cartilage

scientific article

Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritis

scientific article published on 18 March 2009

Human hip joint cartilage: MRI quantitative thickness and volume measurements discriminating acetabulum and femoral head

scientific article

Identification in human osteoarthritic chondrocytes of proteins binding to the novel regulatory site AGRE in the human matrix metalloprotease 13 proximal promoter

scientific article

Impact of disease treatments on the progression of knee osteoarthritis structural changes related to meniscal extrusion: Data from the OAI progression cohort

scientific article

Impact of oral osteoarthritis therapy usage among other risk factors on knee replacement: a nested case-control study using the Osteoarthritis Initiative cohort

In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritis.

scientific article

In vivo effect of opticin deficiency in cartilage in a surgically induced mouse model of osteoarthritis ⬇️

scientific article published on 11 January 2018

Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage

scientific article published on 18 December 2008

Influence of Tumor Necrosis Factor α, Parathyroid Hormone, and Vitamin D3 on Modulation of the RANKL2 Isoform: A Pilot Study

scientific article

Inhibition of interleukin-1beta-induced cyclooxygenase 2 expression in human synovial fibroblasts by 15-deoxy-Delta12,14-prostaglandin J2 through a histone deacetylase-independent mechanism

scientific article published in January 2005

Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2.

scientific article published in November 2008

Interleukin 17 (IL-17) induces collagenase-3 production in human osteoarthritic chondrocytes via AP-1 dependent activation: differential activation of AP-1 members by IL-17 and IL-1beta

scientific article

Intra-articular corticosteroid knee injection induces a reduction in meniscal thickness with no treatment effect on cartilage volume: a case-control study

scientific article published on 14 August 2020

Intra-articular hyaluronic acid in the treatment of knee osteoarthritis: a Canadian evidence-based perspective

scientific article published on 12 September 2017

Kinetic peak vertical force measurement in cats afflicted by coxarthritis: data management and acquisition protocols

scientific article

Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume

scientific article published in January 2007

Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis.

scientific article published in April 2005

Levels of serum biomarkers from a two-year multicentre trial are associated with treatment response on knee osteoarthritis cartilage loss as assessed by magnetic resonance imaging: an exploratory study

scientific article published on 20 July 2017

Licofelone (ML-3000), a dual inhibitor of 5-lipoxygenase and cyclooxygenase, reduces the level of cartilage chondrocyte death in vivo in experimental dog osteoarthritis: inhibition of pro-apoptotic factors

scientific article

Long term evaluation of disease progression through the quantitative magnetic resonance imaging of symptomatic knee osteoarthritis patients: correlation with clinical symptoms and radiographic changes

scientific article

Long-Term Effects of Glucosamine and Chondroitin Sulfate on the Progression of Structural Changes in Knee Osteoarthritis: Six-Year Followup Data From the Osteoarthritis Initiative

scientific article

Low sirtuin 1 levels in human osteoarthritis subchondral osteoblasts lead to abnormal sclerostin expression which decreases Wnt/β-catenin activity

scientific article

Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes

scientific article

Magnetic Resonance Imaging-Assessed Vastus Medialis Muscle Fat Content and Risk for Knee Osteoarthritis Progression: Relevance From a Clinical Trial

scientific article

Measuring Disease Progression in Osteoarthritis

Meniscal extrusion predicts increases in subchondral bone marrow lesions and bone cysts and expansion of subchondral bone in osteoarthritic knees

scientific article published on 24 February 2010

Meniscal extrusion promotes knee osteoarthritis structural progression: protective effect of strontium ranelate treatment in a phase III clinical trial

scientific article published on 23 March 2015

Meniscal tear as an osteoarthritis risk factor in a largely non-osteoarthritic cohort: a cross-sectional study.

scientific article published on 15 March 2007

Modulation of OPG, RANK and RANKL by human chondrocytes and their implication during osteoarthritis

scientific article published on 17 September 2009

Modulation of insulin-like growth factor 1 levels in human osteoarthritic subchondral bone osteoblasts

scientific article

Most recent developments in strategies to reduce the progression of structural changes in osteoarthritis: today and tomorrow

scientific article

NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis

scientific article

Natural history and clinical significance of meniscal tears over 8 years in a midlife cohort

scientific article published on 5 January 2016

New and emerging treatments for osteoarthritis management: will the dream come true with personalized medicine?

scientific article

New insights into the major pathophysiological processes responsible for the development of osteoarthritis.

scientific article

New perspective in osteoarthritis: the OPG and RANKL system as a potential therapeutic target?

scientific article published on March 2009

New thoughts on the pathophysiology of osteoarthritis: one more step toward new therapeutic targets

scientific article

New trends in the treatment of osteoarthritis.

scientific article

Nimesulide, a preferential cyclooxygenase 2 inhibitor, suppresses peroxisome proliferator-activated receptor induction of cyclooxygenase 2 gene expression in human synovial fibroblasts: evidence for receptor antagonism

scientific article

Nitric oxide induced cell death in human osteoarthritic synoviocytes is mediated by tyrosine kinase activation and hydrogen peroxide and/or superoxide formation

scientific article published in October 2002

Oral treatment with PD-0200347, an alpha2delta ligand, reduces the development of experimental osteoarthritis by inhibiting metalloproteinases and inducible nitric oxide synthase gene expression and synthesis in cartilage chondrocytes

scientific article published in February 2005

Osteoarthritis ⬇️

article by Johanne Martel-Pelletier et al published 13 October 2016 in Nature Reviews Disease Primers

Osteoarthritis: a metabolic disease induced by local abnormal leptin activity?

scientific article published in April 2005

PPARgamma ligands as modulators of inflammatory and catabolic responses in arthritis. An overview.

scientific article

PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage

scientific article published on 8 January 2015

Peak vertical force in a stabilized canine cranial cruciate deficient stifle model: A one-year follow-up.

scientific article

Peroxisome proliferator-activated receptor gamma in osteoarthritis ⬇️

scientific article published on 04 September 2010

Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytes

scientific article published on January 2007

Pioglitazone, a peroxisome proliferator-activated receptor gamma agonist, reduces the progression of experimental osteoarthritis in guinea pigs

scientific article published in February 2005

Protective effects of total fraction of avocado/soybean unsaponifiables on the structural changes in experimental dog osteoarthritis: inhibition of nitric oxide synthase and matrix metalloproteinase-13.

scientific article published on 16 March 2009

Proteinase-activated Receptor-2 Gene Disruption Limits the Effect of Osteoarthritis on Cartilage in Mice: A Novel Target in Joint Degradation ⬇️

scientific article published on February 1, 2011

Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts

scientific article

R-spondins are newly recognized players in osteoarthritis that regulate Wnt signaling in osteoblasts

scientific article published in December 2011

Refinement of the Montreal Instrument for Cat Arthritis Testing, for Use by Veterinarians: detection of naturally occurring osteoarthritis in laboratory cats

scientific article published in September 2017

Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes

scientific article

Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids

scientific article published in December 2004

Relationship between bone marrow lesions, cartilage loss and pain in knee osteoarthritis: results from a randomised controlled clinical trial using MRI.

scientific article published on 7 July 2010

Response to "Bio-optimized Curcuma longa extract is efficient on knee osteoarthritis pain: a double-blind multicenter randomized placebo controlled three-arm study"

scientific article published on 11 February 2020

Response to: 'Concerns about report suggesting glucosamine and chondroitin protect against cartilage loss' by Felson.

scientific article published in April 2015

Responsiveness of magnetic resonance imaging-derived measures over 2.7 years

scientific article published on 15 August 2014

Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthri

scientific article published on November 2006

Risk factors associated with the loss of cartilage volume on weight-bearing areas in knee osteoarthritis patients assessed by quantitative magnetic resonance imaging: a longitudinal study

scientific article

Role of Lipocalin-type prostaglandin D synthase in experimental osteoarthritis

scientific article published on 26 April 2020

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis ⬇️

scientific article published on November 30, 2010

Safety and efficacy of long-term intraarticular steroid injections in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled trial

scientific article published on February 2003

Sensitivity of functional targeted neuropeptide evaluation in testing pregabalin analgesic efficacy in a rat model of osteoarthritis pain

scientific article published on 23 May 2019

Skeletal involvement in the pathogenesis and outcomes of rheumatoid arthritis and osteoarthritis.

scientific article

Strontium ranelate inhibits key factors affecting bone remodeling in human osteoarthritic subchondral bone osteoblasts

scientific article published on 12 June 2011

Strontium ranelate reduces the progression of experimental dog osteoarthritis by inhibiting the expression of key proteases in cartilage and of IL-1β in the synovium

scientific article published on 13 October 2012

Study of the role of leukotriene B()4 in abnormal function of human subchondral osteoarthritis osteoblasts: effects of cyclooxygenase and/or 5-lipoxygenase inhibition

scientific article

Synthesis of interleukin 1beta, tumor necrosis factor-alpha, and interstitial collagenase (MMP-1) is eicosanoid dependent in human osteoarthritis synovial membrane explants: interactions with antiinflammatory cytokines

scientific article

Targeting subchondral bone for treating osteoarthritis: what is the evidence?

scientific article published on February 2010

Ten years in the life of an enzyme: the story of the human MMP-13 (collagenase-3).

scientific article published on January 2004

The Novartis-ILAR Rheumatology Prize 2001 Osteoarthritis: from molecule to man

scientific article

The association between objectively measured physical activity and knee structural change using MRI.

scientific article

The association between subchondral bone cysts and tibial cartilage volume and risk of joint replacement in people with knee osteoarthritis: a longitudinal study

scientific article

The in situ up-regulation of chondrocyte interleukin-1-converting enzyme and interleukin-18 levels in experimental osteoarthritis is mediated by nitric oxide

scientific article published in October 2002

The in vivo effect of prophylactic subchondral bone protection of osteoarthritic synovial membrane in bone-specific Ephb4-overexpressing mice.

scientific article published on 29 November 2014

The inhibition of subchondral bone resorption in the early phase of experimental dog osteoarthritis by licofelone is associated with a reduction in the synthesis of MMP-13 and cathepsin K.

scientific article published in March 2004

The levels of the adipokines adipsin and leptin are associated with knee osteoarthritis progression as assessed by MRI and incidence of total knee replacement in symptomatic osteoarthritis patients: a post hoc analysis

scientific article published on 11 December 2015

The longitudinal relationship between changes in body weight and changes in medial tibial cartilage, and pain among community-based adults with and without meniscal tears

scientific article published on 6 June 2013

The offspring of people with a total knee replacement for severe primary knee osteoarthritis have a higher risk of worsening knee pain over 8 years

article by Feng Pan et al published 4 December 2014 in Annals of the Rheumatic Diseases

The presence of meniscal lesions is a strong predictor of neuropathic pain in symptomatic knee osteoarthritis: a cross-sectional pilot study

scientific article

The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanases.

scientific article

The role of cytokines in osteoarthritis pathophysiology

scientific article

The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein

scientific article published on January 2006

The unfolded protein response genes in human osteoarthritic chondrocytes: PERK emerges as a potential therapeutic target

scientific article published on 19 July 2016

Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model

scientific article published on 21 June 2011

Total Knee Replacement as a Knee Osteoarthritis Outcome: Predictors Derived from a 4-Year Long-Term Observation following a Randomized Clinical Trial Using Chondroitin Sulfate

scientific article

Treatment with ephrin B2 positively impacts the abnormal metabolism of human osteoarthritic chondrocytes

scientific article published on 7 August 2009

Validity of Combining History Elements and Physical Examination Tests to Diagnose Patellofemoral Pain

scientific article

Variable effects of 3 different chondroitin sulfate compounds on human osteoarthritic cartilage/chondrocytes: relevance of purity and production process

scientific article published on 28 January 2010

Viewpoint on Time Series and Interrupted Time Series Optimum Modeling for Predicting Arthritic Disease Outcomes

scientific article published on 20 May 2020

[(18)F]-fluorodeoxyglucose positron emission tomography of the cat brain: A feasibility study to investigate osteoarthritis-associated pain

scientific article published on 25 March 2015

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