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List of works by Gregory E. Amidon

Application of powder X-ray diffraction in studying the compaction behavior of bulk pharmaceutical powders

scientific article published on 01 November 2005

Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in vivo approach.

scientific article published on 25 January 2018

Evaluation of a three compartment in vitro gastrointestinal simulator dissolution apparatus to predict in vivo dissolution

scientific article

Evaluation of the effects of tableting speed on the relationships between compaction pressure, tablet tensile strength, and tablet solid fraction

scientific article published on 01 March 2005

Exploring Bioequivalence of Dexketoprofen Trometamol Drug Products with the Gastrointestinal Simulator (GIS) and Precipitation Pathways Analyses

scientific article published on 15 March 2019

Fifty-Eight Years and Counting: High-Impact Publishing in Computational Pharmaceutical Sciences and Mechanism-Based Modeling

scientific article published on 10 November 2018

Formulation predictive dissolution (fPD) testing to advance oral drug product development: An introduction to the US FDA funded '21st Century BA/BE' project

scientific article published on 23 June 2018

Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach

scientific article published on 29 May 2018

Hierarchical Mass Transfer Analysis of Drug Particle Dissolution, Highlighting the Hydrodynamics, pH, Particle Size and Buffer Effects for Dissolution of Ionizable and non-Ionizable Drugs in a Compendial Dissolution Vessel

scientific article published on 04 September 2020

In Vitro Characterization of the Biomimetic Properties of Poly(dimethylsiloxane) To Simulate Oral Drug Absorption.

scientific article

In Vitro Dissolution of Fluconazole and Dipyridamole in Gastrointestinal Simulator (GIS), Predicting in Vivo Dissolution and Drug-Drug Interaction Caused by Acid-Reducing Agents

scientific article published on 27 May 2015

In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance

scientific article published on 06 September 2018

In Vivo Predictive Dissolution: Comparing the Effect of Bicarbonate and Phosphate Buffer on the Dissolution of Weak Acids and Weak Bases.

scientific article published on 15 May 2015

In Vivo Predictive Dissolution: Transport Analysis of the CO2, Bicarbonate In Vivo Buffer System

scientific article (publication date: November 2014)

In vitro dissolution methodology, mini-Gastrointestinal Simulator (mGIS), predicts better in vivo dissolution of a weak base drug, dasatinib.

scientific article

Linking the Gastrointestinal Behavior of Ibuprofen with The Systemic Exposure Between and Within Humans - Part 1: Fasted State

scientific article published on 12 November 2018

Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State

scientific article published on 12 November 2018

Magnetic Resonance Imaging Quantification of Fasted State Colonic Liquid Pockets in Healthy Humans.

scientific article

Mass Transport Analysis of Bicarbonate Buffer: Effect of the CO2-H2CO3 Hydration-Dehydration Kinetics in the Fluid Boundary Layer and the Apparent Effective p Ka Controlling Dissolution of Acids and Bases

scientific article published on 13 May 2019

Mass Transport Analysis of the Enhanced Buffer Capacity of the Bicarbonate-CO Buffer in a Phase-Heterogenous System: Physiological and Pharmaceutical Significance

scientific article published on 26 October 2018

Mechanistic Analysis Of Co-Crystal Dissolution, Surface Ph, And Dissolution Advantage As A Guide For Rational Selection

scientific article published on 29 September 2018

Mechanistic Analysis of Cocrystal Dissolution as a Function of pH and Micellar Solubilization

scientific article published on 15 February 2016

Mechanistic Basis of Cocrystal Dissolution Advantage

scientific article

Mechanistic analysis of solute transport in an in vitro physiological two-phase dissolution apparatus ⬇️

scientific article published on 4 September 2012

Mechanistic study of the effect of roller compaction and lubricant on tablet mechanical strength

scientific article published on 01 May 2007

Oral Bioperformance and 21st Century Dissolution ⬇️

scientific article published on 08 September 2010

Particle size limits to meet USP content uniformity criteria for tablets and capsules

scientific article published in May 2006

Physiological parameters for oral delivery and in vitro testing

scientific article

Printing of small molecular medicines from the vapor phase.

scientific article published on 27 September 2017

Quantification of gastrointestinal liquid volumes and distribution following a 240 mL dose of water in the fasted state

scientific article

Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties

scientific article published on 27 January 2020

The Combination of GIS and Biphasic to Better Predict In Vivo Dissolution of BCS Class IIb Drugs, Ketoconazole and Raloxifene

scientific article

The Evaluation of In Vitro Drug Dissolution of Commercially Available Oral Dosage Forms for Itraconazole in Gastrointestinal Simulator With Biorelevant Media.

scientific article

The Solubility–Permeability Interplay: Mechanistic Modeling and Predictive Application of the Impact of Micellar Solubilization on Intestinal Permeation ⬇️

scientific article published on August 11, 2011

The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS)

scientific article published on 03 March 2017

The solubility-permeability interplay in using cyclodextrins as pharmaceutical solubilizers: mechanistic modeling and application to progesterone

scientific article published in June 2010

Ultra-Thin, Large-Area Membrane Diffusion Cell for pH-Dependent Simultaneous Dissolution and Absorption Studies

scientific article published on 05 June 2020

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