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List of works by Sebastian Diecke

A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases

scientific article

A cellular model of Brugada syndrome with SCN10A variants using human-induced pluripotent stem cell-derived cardiomyocytes

scientific article published on 01 September 2019

Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy

scientific article published on 17 July 2019

Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics

scientific article published on August 2017

Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay

scientific article published on 05 November 2020

Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo

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Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system

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Chemically defined generation of human cardiomyocytes

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Corrigendum to Flemming J, Marczenke M, Rudolph I-M, et al. Induced pluripotent stem cell-based disease modeling identifies ligand-induced decay of megalin as a cause of Donnai-Barrow syndrome. Kidney Int. 2020;98:159-167

scientific article

Costimulation-adhesion blockade is superior to cyclosporine A and prednisone immunosuppressive therapy for preventing rejection of differentiated human embryonic stem cells following transplantation

scientific article published on November 2013

Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene-edited human-induced pluripotent stem cell-derived cardiomyocytes and preclinical drug screening

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome

scientific article published on 26 March 2021

Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity

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Embryos and embryonic stem cells from the white rhinoceros.

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Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates

scientific article published on 28 July 2020

E‐cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming

scientific article published on July 1, 2011

FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells

scientific article published on 02 August 2018

FGF2 signaling in mouse embryonic fibroblasts is crucial for self-renewal of embryonic stem cells

scientific article published on 11 March 2008

Generation of 20 human induced pluripotent stem cell lines from patients with focal segmental glomerulosclerosis (FSGS)

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Generation of Functional Cardiomyocytes from the Synoviocytes of Patients with Rheumatoid Arthritis via Induced Pluripotent Stem Cells

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Generation of disease-specific induced pluripotent stem cells from patients with rheumatoid arthritis and osteoarthritis

scientific article published on 04 February 2014

Generation of hiPSC-Derived Skeletal Muscle Cells: Exploiting the Potential of Skeletal Muscle-Derived hiPSCs

scientific article published on 23 May 2022

Generation of three age and gender matched pairs of human induced pluripotent stem cells derived from myoblasts (MDCi011-A, MDCi012-A, MDCi013-A) and from peripheral blood mononuclear cells (MDCi011-B, MDCi012-B, MDCi013-B) from the same donor

scientific article published on 08 September 2020

Generation of two human induced pluripotent stem cell lines derived from myoblasts (MDCi014-A) and from peripheral blood mononuclear cells (MDCi014-B) from the same donor

scientific article published on 17 September 2020

Human and equine endothelial cells in a life cell imaging scratch assay in vitro

scientific article published on 01 January 2018

Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus B3-induced myocarditis and antiviral drug screening platform

scientific article

Identification of prion protein binding proteins by combined use of far-Western immunoblotting, two dimensional gel electrophoresis and mass spectrometry

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Improved approach for chondrogenic differentiation of human induced pluripotent stem cells

scientific article published on April 2015

Induced pluripotent stem cell-based disease modeling identifies ligand-induced decay of megalin as a cause of Donnai-Barrow syndrome

scientific article published on 24 March 2020

Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros

scientific article published in 2022

Intronic CRISPR Repair in a Preclinical Model of Noonan Syndrome-Associated Cardiomyopathy

scientific article published on 06 July 2020

Methods for Automated Single Cell Isolation and Sub-Cloning of Human Pluripotent Stem Cells

scientific article published on 01 December 2020

Microfluidic Single-Cell Analysis of Transplanted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes After Acute Myocardial Infarction

scientific article published on August 2015

Modeling Cardiovascular Diseases with Patient-Specific Human Pluripotent Stem Cell-Derived Cardiomyocytes

scientific article published on 18 February 2015

Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs

scientific article published on 06 September 2018

Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction

scientific article published in 2022

Novel calcineurin A (PPP3CA) variant associated with epilepsy, constitutive enzyme activation and downregulation of protein expression

scientific article published on 25 September 2018

Novel codon-optimized mini-intronic plasmid for efficient, inexpensive, and xeno-free induction of pluripotency.

scientific article

Phosphatidylinositol 3,5-bisphosphate facilitates axonal vesicle transport and presynapse assembly

scientific article published on 12 October 2023

Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism

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Pushing the reset button: chemical-induced conversion of amniotic fluid stem cells into a pluripotent state

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Recent technological updates and clinical applications of induced pluripotent stem cells

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Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand?

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Rewinding the process of mammalian extinction

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Second generation codon optimized minicircle (CoMiC) for nonviral reprogramming of human adult fibroblasts.

scientific article published on January 2014

Simple Workflow and Comparison of Media for hPSC-Cardiomyocyte Cryopreservation and Recovery

scientific article published on 01 December 2020

Studying Brugada Syndrome With an SCN1B Variants in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

scientific article published on 01 November 2019

The ART of bringing extinction to a freeze – History and future of species conservation, exemplified by rhinos

scientific article published in 2021

The Translational Landscape of the Human Heart

scientific article published on 30 May 2019

The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells

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Transcriptomic and epigenomic differences in human induced pluripotent stem cells generated from six reprogramming methods

scientific article published on 03 October 2017

Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance

scientific article