List of works - Gerjo J. V. M. van Osch

A role for subchondral bone changes in the process of osteoarthritis; a micro-CT study of two canine models.

scientific article

Accuracy of magnetic resonance imaging to detect cartilage loss in severe osteoarthritis of the first carpometacarpal joint: comparison with histological evaluation

scientific article published on 14 March 2017

Activin Receptor-Like Kinase Receptors ALK5 and ALK1 Are Both Required for TGFβ-Induced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells

scientific article published on 31 December 2015

An osteochondral culture model to study mechanisms involved in articular cartilage repair.

scientific article

Analysis of osteoarthritis in a mouse model of the progeroid human DNA repair syndrome trichothiodystrophy.

scientific article

Association between weight or body mass index and hand osteoarthritis: a systematic review

scientific article published on 31 May 2009

Auto-crosslinked hyaluronic acid gel accelerates healing of rabbit flexor tendons in vivo

scientific article published on March 2009

Can one generate stable hyaline cartilage from adult mesenchymal stem cells? A developmental approach ⬇️

scientific article published on November 21, 2011

Cartilage Oligomeric Matrix Protein-Derived Peptides Secreted by Cartilage Do Not Induce Responses Commonly Observed during Osteoarthritis

scientific article published on 29 September 2020

Cartilage Regeneration in the Head and Neck Area: Combination of Ear or Nasal Chondrocytes and Mesenchymal Stem Cells Improves Cartilage Production

scientific article

Cartilage repair: past and future--lessons for regenerative medicine.

scientific article published on 15 May 2009

Chondrogenesis of mesenchymal stem cells in an osteochondral environment is mediated by the subchondral bone.

scientific article published on 02 October 2013

Clinically translatable cell tracking and quantification by MRI in cartilage repair using superparamagnetic iron oxides

scientific article

Cytokine profiles in the joint depend on pathology, but are different between synovial fluid, cartilage tissue and cultured chondrocytes

scientific article

Differential gene expression of the intermediate and outer interzone layers of developing articular cartilage in murine embryos

scientific article

Effect of Cell Seeding Density and Inflammatory Cytokines on Adipose Tissue-Derived Stem Cells: an in Vitro Study

scientific article published on 24 January 2017

Emerging potential of gene silencing approaches targeting anti-chondrogenic factors for cell-based cartilage repair

scientific article

FGF, TGFβand Wnt crosstalk: embryonic toin vitrocartilage development from mesenchymal stem cells ⬇️

scientific article published on April 11, 2013

Fibrates as therapy for osteoarthritis and rheumatoid arthritis? A systematic review ⬇️

scientific article published on February 1, 2013

Follistatin Effects in Migration, Vascularization, and Osteogenesis in vitro and Bone Repair in vivo

Improved cartilage integration and interfacial strength after enzymatic treatment in a cartilage transplantation model

scientific article

In vitro model to study chondrogenic differentiation in tendinopathy

scientific article

In vitro modulation of the behavior of adhering macrophages by medications is biomaterial-dependent.

scientific article

In-vivo generation of bone via endochondral ossification by in-vitro chondrogenic priming of adult human and rat mesenchymal stem cells

scientific article

Increased physical activity severely induces osteoarthritic changes in knee joints with papain induced sulfate-glycosaminoglycan depleted cartilage

scientific article published on 29 January 2014

Inflammatory Cells in Patients with Endstage Knee Osteoarthritis: A Comparison between the Synovium and the Infrapatellar Fat Pad.

scientific article

Intrinsic differentiation potential of adolescent human tendon tissue: an in-vitro cell differentiation study.

scientific article

Is T1ρ Mapping an Alternative to Delayed Gadolinium-enhanced MR Imaging of Cartilage in the Assessment of Sulphated Glycosaminoglycan Content in Human Osteoarthritic Knees? An in Vivo Validation Study.

scientific article

Lack of high BMI-related features in adipocytes and inflammatory cells in the infrapatellar fat pad (IFP).

scientific article published on 11 August 2017

Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation

scientific article

Mechanical and biochemical mapping of human auricular cartilage for reliable assessment of tissue-engineered constructs

scientific article published on 28 May 2015

Mesenchymal stem cells reduce pain but not degenerative changes in a mono-iodoacetate rat model of osteoarthritis.

scientific article published on 16 May 2014

Nell-1, HMGB1 and CCN2 enhance migration and vasculogenesis, but not osteogenic differentiation compared to BMP2.

scientific article published on 2 May 2017

No clear association between female hormonal aspects and osteoarthritis of the hand, hip and knee: a systematic review

scientific article published on 16 July 2009

Novel In Situ Gelling Hydrogels Loaded with Recombinant Collagen Peptide Microspheres as a Slow-Release System Induce Ectopic Bone Formation

scientific article published on 01 December 2018

Novel In Situ Gelling Hydrogels Loaded with Recombinant Collagen Peptide Microspheres as a Slow-Release System Induce Ectopic Bone Formation

scientific article published on 19 September 2018

Novel bilayer bacterial nanocellulose scaffold supports neocartilage formation in vitro and in vivo

scientific article

Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis

scientific article

Osteoarthritis induction leads to early and temporal subchondral plate porosity in the tibial plateau of mice: an in vivo microfocal computed tomography study.

scientific article published in September 2011

Prevention of knee osteoarthritis in overweight females: the first preventive randomized controlled trial in osteoarthritis

scientific article published on 26 March 2015

Profiling the secretion of soluble mediators by end stage osteoarthritis synovial tissue explants reveals a reduced responsiveness to an inflammatory trigger

scientific article

Quantitative evaluation of mechanical properties in tissue-engineered auricular cartilage

scientific article published on 03 July 2013

Regenerative medicine--initiative à la carte. A remedy to the blood thirsty count Dracula?

scientific article published on 13 June 2008

SMAD3 and SMAD4 have a more dominant role than SMAD2 in TGFβ-induced chondrogenic differentiation of bone marrow-derived mesenchymal stem cells

scientific article published on 27 February 2017

Silencing of anti-chondrogenic microRNA-221 in human mesenchymal stem cells promotes cartilage repair in vivo

scientific article

Soluble mediators in posttraumatic wrist and primary knee osteoarthritis

scientific article published on 15 September 2014

Stimulation of fibrotic processes by the infrapatellar fat pad in cultured synoviocytes from patients with osteoarthritis: a possible role for prostaglandin f2α.

scientific article published in August 2013

The effect of glucosamine sulphate on osteoarthritis: design of a long-term randomised clinical trial [ISRCTN54513166].

scientific article

The role of hypoxia in bone marrow-derived mesenchymal stem cells: considerations for regenerative medicine approaches

scientific article published on April 2010

Tissue composition regulates distinct viscoelastic responses in auricular and articular cartilage.

scientific article

White paper on how to go forward with cell-based advanced therapies in Europe

scientific article

β1 Integrins Mediate Attachment of Mesenchymal Stem Cells to Cartilage Lesions

scientific article published in January 2015

List of works by Gerjo J. V. M. van Osch

A role for subchondral bone changes in the process of osteoarthritis; a micro-CT study of two canine models.

Accuracy of magnetic resonance imaging to detect cartilage loss in severe osteoarthritis of the first carpometacarpal joint: comparison with histological evaluation

Activin Receptor-Like Kinase Receptors ALK5 and ALK1 Are Both Required for TGFβ-Induced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells

An osteochondral culture model to study mechanisms involved in articular cartilage repair.

Analysis of osteoarthritis in a mouse model of the progeroid human DNA repair syndrome trichothiodystrophy.

Association between weight or body mass index and hand osteoarthritis: a systematic review

Auto-crosslinked hyaluronic acid gel accelerates healing of rabbit flexor tendons in vivo

Can one generate stable hyaline cartilage from adult mesenchymal stem cells? A developmental approach ⬇️

Cartilage Oligomeric Matrix Protein-Derived Peptides Secreted by Cartilage Do Not Induce Responses Commonly Observed during Osteoarthritis

Cartilage Regeneration in the Head and Neck Area: Combination of Ear or Nasal Chondrocytes and Mesenchymal Stem Cells Improves Cartilage Production

Cartilage repair: past and future--lessons for regenerative medicine.

Chondrogenesis of mesenchymal stem cells in an osteochondral environment is mediated by the subchondral bone.

Clinically translatable cell tracking and quantification by MRI in cartilage repair using superparamagnetic iron oxides

Cytokine profiles in the joint depend on pathology, but are different between synovial fluid, cartilage tissue and cultured chondrocytes

Differential gene expression of the intermediate and outer interzone layers of developing articular cartilage in murine embryos

Effect of Cell Seeding Density and Inflammatory Cytokines on Adipose Tissue-Derived Stem Cells: an in Vitro Study

Emerging potential of gene silencing approaches targeting anti-chondrogenic factors for cell-based cartilage repair

FGF, TGFβand Wnt crosstalk: embryonic toin vitrocartilage development from mesenchymal stem cells ⬇️

Fibrates as therapy for osteoarthritis and rheumatoid arthritis? A systematic review ⬇️

Follistatin Effects in Migration, Vascularization, and Osteogenesis in vitro and Bone Repair in vivo

Improved cartilage integration and interfacial strength after enzymatic treatment in a cartilage transplantation model

In vitro model to study chondrogenic differentiation in tendinopathy

In vitro modulation of the behavior of adhering macrophages by medications is biomaterial-dependent.

In-vivo generation of bone via endochondral ossification by in-vitro chondrogenic priming of adult human and rat mesenchymal stem cells

Increased physical activity severely induces osteoarthritic changes in knee joints with papain induced sulfate-glycosaminoglycan depleted cartilage

Inflammatory Cells in Patients with Endstage Knee Osteoarthritis: A Comparison between the Synovium and the Infrapatellar Fat Pad.

Intrinsic differentiation potential of adolescent human tendon tissue: an in-vitro cell differentiation study.

Is T1ρ Mapping an Alternative to Delayed Gadolinium-enhanced MR Imaging of Cartilage in the Assessment of Sulphated Glycosaminoglycan Content in Human Osteoarthritic Knees? An in Vivo Validation Study.

Lack of high BMI-related features in adipocytes and inflammatory cells in the infrapatellar fat pad (IFP).

Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation

Mechanical and biochemical mapping of human auricular cartilage for reliable assessment of tissue-engineered constructs

Mesenchymal stem cells reduce pain but not degenerative changes in a mono-iodoacetate rat model of osteoarthritis.

Nell-1, HMGB1 and CCN2 enhance migration and vasculogenesis, but not osteogenic differentiation compared to BMP2.

No clear association between female hormonal aspects and osteoarthritis of the hand, hip and knee: a systematic review

Novel In Situ Gelling Hydrogels Loaded with Recombinant Collagen Peptide Microspheres as a Slow-Release System Induce Ectopic Bone Formation

Novel In Situ Gelling Hydrogels Loaded with Recombinant Collagen Peptide Microspheres as a Slow-Release System Induce Ectopic Bone Formation

Novel bilayer bacterial nanocellulose scaffold supports neocartilage formation in vitro and in vivo

Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis

Osteoarthritis induction leads to early and temporal subchondral plate porosity in the tibial plateau of mice: an in vivo microfocal computed tomography study.

Prevention of knee osteoarthritis in overweight females: the first preventive randomized controlled trial in osteoarthritis

Profiling the secretion of soluble mediators by end stage osteoarthritis synovial tissue explants reveals a reduced responsiveness to an inflammatory trigger

Quantitative evaluation of mechanical properties in tissue-engineered auricular cartilage

Regenerative medicine--initiative à la carte. A remedy to the blood thirsty count Dracula?

SMAD3 and SMAD4 have a more dominant role than SMAD2 in TGFβ-induced chondrogenic differentiation of bone marrow-derived mesenchymal stem cells

Silencing of anti-chondrogenic microRNA-221 in human mesenchymal stem cells promotes cartilage repair in vivo

Soluble mediators in posttraumatic wrist and primary knee osteoarthritis

Stimulation of fibrotic processes by the infrapatellar fat pad in cultured synoviocytes from patients with osteoarthritis: a possible role for prostaglandin f2α.

The effect of glucosamine sulphate on osteoarthritis: design of a long-term randomised clinical trial [ISRCTN54513166].

The role of hypoxia in bone marrow-derived mesenchymal stem cells: considerations for regenerative medicine approaches

Tissue composition regulates distinct viscoelastic responses in auricular and articular cartilage.

White paper on how to go forward with cell-based advanced therapies in Europe

β1 Integrins Mediate Attachment of Mesenchymal Stem Cells to Cartilage Lesions