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List of works by Kazuaki Nagashima

14-3-3 and calmodulin control subcellular distribution of Kir/Gem and its regulation of cell shape and calcium channel activity

scientific article

BARP suppresses voltage-gated calcium channel activity and Ca2+-evoked exocytosis

scientific journal article

Cdk5-dependent regulation of glucose-stimulated insulin secretion.

scientific article published on 11 September 2005

Clinical and functional characterization of the Pro1198Leu ABCC8 gene mutation associated with permanent neonatal diabetes mellitus

scientific article

Direct inhibition of the interaction between alpha-interaction domain and beta-interaction domain of voltage-dependent Ca2+ channels by Gem.

scientific article

Essential role of ubiquitin-proteasome system in normal regulation of insulin secretion

scientific article published on 16 March 2006

Exophilin4/Slp2-a targets glucagon granules to the plasma membrane through unique Ca2+-inhibitory phospholipid-binding activity of the C2A domain

scientific article

Gatifloxacin acutely stimulates insulin secretion and chronically suppresses insulin biosynthesis

scientific article published on 28 September 2006

Glucose-stimulated single pancreatic islets sustain increased cytosolic ATP levels during initial Ca2+ influx and subsequent Ca2+ oscillations.

scientific article published on 3 December 2013

Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions

scientific article

Mutations in KCNJ11 are associated with the development of autosomal dominant, early-onset type 2 diabetes

scientific article published on 10 September 2013

Nuclear Transport of Kir/Gem Requires Specific Signals and Importin α5 and Is Regulated by Calmodulin and Predicted Serine Phosphorylations

scientific article published on 01 July 2007

Nuclear sequestration of beta-subunits by Rad and Rem is controlled by 14-3-3 and calmodulin and reveals a novel mechanism for Ca2+ channel regulation.

scientific article published on 8 November 2005

Oral Administration of Apple Procyanidins Ameliorates Insulin Resistance via Suppression of Pro-Inflammatory Cytokine Expression in Liver of Diabetic ob/ob Mice.

scientific article

Palmitate induces reactive oxygen species production and β-cell dysfunction by activating nicotinamide adenine dinucleotide phosphate oxidase through Src signaling

scientific article published on 3 October 2013

Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass by epigenetic modification of Cdkn1c

scientific article published on 22 June 2015

Reduction of reactive oxygen species ameliorates metabolism-secretion coupling in islets of diabetic GK rats by suppressing lactate overproduction

scientific article published on 24 January 2013

Roles of 14-3-3 and calmodulin binding in subcellular localization and function of the small G-protein Rem2.

scientific article

Src regulates insulin secretion and glucose metabolism by influencing subcellular localization of glucokinase in pancreatic β-cells

scientific article published on 13 September 2015

Sulfonylurea and non-sulfonylurea hypoglycemic agents: pharmachological properties and tissue selectivity

scientific article

Transcriptional regulatory factor X6 (Rfx6) increases gastric inhibitory polypeptide (GIP) expression in enteroendocrine K-cells and is involved in GIP hypersecretion in high fat diet-induced obesity.

scientific article

Utility of indices using C-peptide levels for indication of insulin therapy to achieve good glycemic control in Japanese patients with type 2 diabetes

scientific article

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