Search filters

List of works by Kestis Vaitkus

Decitabine increases fetal hemoglobin in Papio anubis by increasing γ-globin gene transcription

scientific article

Developmental changes in DNA methylation and covalent histone modifications of chromatin associated with the epsilon-, gamma-, and beta-globin gene promoters in Papio anubis

scientific article published on 9 March 2006

Effect of 5-aza-2'-deoxycytidine (Dacogen) on covalent histone modifications of chromatin associated with the epsilon-, gamma-, and beta-globin promoters in Papio anubis

scientific article published on 01 March 2006

Efficacy and safety of long-term RN-1 treatment to increase HbF in baboons

scientific article published in December 2016

Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation

scientific article published on January 2015

Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons

scientific article published on 17 August 2018

RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model

scientific article published on 27 April 2015

S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis)

scientific article published on 8 October 2010

The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis).

scientific article published on 8 February 2016

The gamma-globin gene promoter progressively demethylates as the hematopoietic stem progenitor cells differentiate along the erythroid lineage in baboon fetal liver and adult bone marrow

scientific article published in January 2007

Transcriptional activation of the gamma-globin gene in baboons treated with decitabine and in cultured erythroid progenitor cells involves different mechanisms.

scientific article

siDNMT1 increases γ-globin expression in chemical inducer of dimerization (CID)−dependent mouse βYAC bone marrow cells and in baboon erythroid progenitor cell cultures ⬇️

scientific article published on October 23, 2010

Paulina is supported by:

About Paulina

Help