List of works - Robert Lukowski

A nonsense mutation in PDE6H causes autosomal-recessive incomplete achromatopsia

scientific article

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017

article

Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel-associated retinopathy

scientific article published on 12 November 2018

Amplified pathogenic actions of angiotensin II in cysteine-rich LIM-only protein 4-negative mouse hearts

scientific article published on 30 January 2017

Anti-interleukin-6 therapy for treatment of high platelet counts in cGMP-dependent protein kinase I gene-targeted mice

scientific article published on 29 August 2013

BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells.

scientific article published on 16 February 2016

BKCa channels expressed in sensory neurons modulate inflammatory pain in mice.

scientific article published on 11 December 2013

Bile Acids Acutely Stimulate Insulin Secretion of Mouse β-Cells via Farnesoid X Receptor Activation and KATP Channel Inhibition ⬇️

scientific article published on April 9, 2012

Cardiac cGMP/cGMP-dependent protein kinase I signalling requires cysteine-rich LIM-only protein 4 (CRP4) to oppose angiotensin II induced hypertrophy and fibrosis

Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase I in cardiomyocytes

scientific article

Cardioprotection by ischemic postconditioning and cGMP-elevating agents involves cardiomyocyte nitric oxide-sensitive guanylyl cyclase

scientific article published on 9 February 2018

Characterization of mice with a deletion of protein kinase G type I in cardiomyocytes and the effect on cardioprotection through either postconditioning or mitochondria-targeted S-nitrosothiol.

scientific article published in August 2011

Control of hypothalamic-pituitary-adrenal stress axis activity by the intermediate conductance calcium-activated potassium channel, SK4.

scientific article published on 31 October 2011

Cyclic GMP Kinase I Modulates Glucagon Release From Pancreatic α-Cells ⬇️

scientific article published on October 26, 2010

Cyclic GMP signaling and mitochondrial BK channels in cardioprotection against ischemia/reperfusion injury.

scientific article published on 2 September 2015

Cyclic GMP/cGMP-dependent protein kinase type I signaling and cysteine-rich LIM-only protein 4 in AngII/AT1R-induced heart hypertrophy and fibrosis.

scientific article published on 2 September 2015

Cyclic guanosine monophosphate-dependent protein kinase I promotes adhesion of primary vascular smooth muscle cells.

scientific article published on 6 August 2008

Expression of cGMP-dependent protein kinase type I in mature white adipocytes.

scientific article published on 22 August 2014

Functional Coupling of Slack Channels and P2X3 Receptors Contributes to Neuropathic Pain Processing

scientific article published on 02 January 2021

IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation.

scientific article

Ionizing radiation induces migration of glioblastoma cells by activating BK K+ channels ⬇️

scientific article published on June 23, 2011

Iron deficiency anemia in cyclic GMP kinase knockout mice

scientific article published on February 2016

KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury

scientific article

KCa3.1 channels modulate the processing of noxious chemical stimuli in mice

scientific article

Kinetics of relaxation by cGMP/cGKI signaling in fundus smooth muscle.

scientific article published on 19 August 2011

Loss of Sodium-Activated Potassium Channel Slack and FMRP Differentially Affect Social Behavior in Mice

scientific article published on 31 May 2018

Neuronal cGMP kinase I is essential for stimulation of duodenal bicarbonate secretion by luminal acid

scientific article published on 17 January 2012

Nucleoside diphosphate kinase B-activated intermediate conductance potassium channels are critical for neointima formation in mouse carotid arteries.

scientific article

Obesogenic and Diabetogenic Effects of High-Calorie Nutrition Require Adipocyte BK Channels

scientific article

Palmitoylation and membrane association of the stress axis regulated insert (STREX) controls BK channel regulation by protein kinase C

scientific article published on 29 July 2012

Protection through postconditioning or a mitochondria-targeted S-nitrosothiol is unaffected by cardiomyocyte-selective ablation of protein kinase G

scientific article published on 20 February 2013

Purkinje cell BKchannel ablation induces abnormal rhythm in deep cerebellar nuclei and prevents LTD.

scientific article published on 9 March 2018

Reply to Kass and Takimoto: Cardiac hypertrophy without cGKI and PDE5 in cardiac myocytes

scientific article published on 24 May 2010

Rescue of cGMP kinase I and the cause of premature death

Rescue of cGMP kinase I knockout mice by smooth muscle specific expression of either isozyme

scientific article

Role of smooth muscle cGMP/cGKI signaling in murine vascular restenosis

scientific article published on 17 April 2008

Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis.

scientific article

SK4 channels modulate Ca2+ signalling and cell cycle progression in murine breast cancer

scientific article published on 30 May 2017

Sildenafil Does Not Prevent Heart Hypertrophy and Fibrosis Induced by Cardiomyocyte Angiotensin II Type 1 Receptor Signaling.

scientific article

Slack channels expressed in sensory neurons control neuropathic pain in mice

scientific article published in January 2015

Stimulation of Slack K(+) Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex.

scientific article published on 17 August 2016

Targeted ablation of the Pde6h gene in mice reveals cross-species differences in cone and rod phototransduction protein isoform inventory.

scientific article

The Na<sup>+</sup>-activated K<sup>+</sup> channel Slack contributes to synaptic development and plasticity

scientific article published on 18 October 2021

The role of cGMP-cGKI-signaling for duodenal bicarbonate secretion.

scientific article published in August 2011

The role of cGMP-cGKI-signaling for duodenal bicarbonate secretion.

scientific article published on 11 August 2009

The sodium-activated potassium channel Slack is required for optimal cognitive flexibility in mice

scientific article

Thrombocytosis as a response to high interleukin-6 levels in cGMP-dependent protein kinase I mutant mice.

scientific article published on 20 June 2013

Transdifferentiation of vascular smooth muscle cells to macrophage-like cells during atherogenesis

scientific article published on 28 July 2014

Turning on cGMP-dependent pathways to treat cardiac dysfunctions: boom, bust, and beyond.

scientific article

[EXPRESS] Slack KNa Channels Influence Dorsal Horn Synapses and Nociceptive Behavior

scientific article

cGKI signaling in cardiac hypertrophy.

scientific article published on 11 August 2009

cGMP kinase I regulates glucagon release

cGMP kinase I, cardiac hypertrophy and PDE inhibition.

scientific article published in August 2011

cGMP regulated protein kinases (cGK).

scientific article published on January 2009

cGMP-Elevating Compounds and Ischemic Conditioning Provide Cardioprotection Against Ischemia and Reperfusion Injury via Cardiomyocyte-Specific BK Channels

scientific article published on 19 October 2017

List of works by Robert Lukowski

A nonsense mutation in PDE6H causes autosomal-recessive incomplete achromatopsia

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017

Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel-associated retinopathy

Amplified pathogenic actions of angiotensin II in cysteine-rich LIM-only protein 4-negative mouse hearts

Anti-interleukin-6 therapy for treatment of high platelet counts in cGMP-dependent protein kinase I gene-targeted mice

BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells.

BKCa channels expressed in sensory neurons modulate inflammatory pain in mice.

Bile Acids Acutely Stimulate Insulin Secretion of Mouse β-Cells via Farnesoid X Receptor Activation and KATP Channel Inhibition ⬇️

Cardiac cGMP/cGMP-dependent protein kinase I signalling requires cysteine-rich LIM-only protein 4 (CRP4) to oppose angiotensin II induced hypertrophy and fibrosis

Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase I in cardiomyocytes

Cardioprotection by ischemic postconditioning and cGMP-elevating agents involves cardiomyocyte nitric oxide-sensitive guanylyl cyclase

Characterization of mice with a deletion of protein kinase G type I in cardiomyocytes and the effect on cardioprotection through either postconditioning or mitochondria-targeted S-nitrosothiol.

Control of hypothalamic-pituitary-adrenal stress axis activity by the intermediate conductance calcium-activated potassium channel, SK4.

Cyclic GMP Kinase I Modulates Glucagon Release From Pancreatic α-Cells ⬇️

Cyclic GMP signaling and mitochondrial BK channels in cardioprotection against ischemia/reperfusion injury.

Cyclic GMP/cGMP-dependent protein kinase type I signaling and cysteine-rich LIM-only protein 4 in AngII/AT1R-induced heart hypertrophy and fibrosis.

Cyclic guanosine monophosphate-dependent protein kinase I promotes adhesion of primary vascular smooth muscle cells.

Expression of cGMP-dependent protein kinase type I in mature white adipocytes.

Functional Coupling of Slack Channels and P2X3 Receptors Contributes to Neuropathic Pain Processing

IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation.

Ionizing radiation induces migration of glioblastoma cells by activating BK K+ channels ⬇️

Iron deficiency anemia in cyclic GMP kinase knockout mice

KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury

KCa3.1 channels modulate the processing of noxious chemical stimuli in mice

Kinetics of relaxation by cGMP/cGKI signaling in fundus smooth muscle.

Loss of Sodium-Activated Potassium Channel Slack and FMRP Differentially Affect Social Behavior in Mice

Neuronal cGMP kinase I is essential for stimulation of duodenal bicarbonate secretion by luminal acid

Nucleoside diphosphate kinase B-activated intermediate conductance potassium channels are critical for neointima formation in mouse carotid arteries.

Obesogenic and Diabetogenic Effects of High-Calorie Nutrition Require Adipocyte BK Channels

Palmitoylation and membrane association of the stress axis regulated insert (STREX) controls BK channel regulation by protein kinase C

Protection through postconditioning or a mitochondria-targeted S-nitrosothiol is unaffected by cardiomyocyte-selective ablation of protein kinase G

Purkinje cell BKchannel ablation induces abnormal rhythm in deep cerebellar nuclei and prevents LTD.

Reply to Kass and Takimoto: Cardiac hypertrophy without cGKI and PDE5 in cardiac myocytes

Rescue of cGMP kinase I and the cause of premature death

Rescue of cGMP kinase I knockout mice by smooth muscle specific expression of either isozyme

Role of smooth muscle cGMP/cGKI signaling in murine vascular restenosis

Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis.

SK4 channels modulate Ca2+ signalling and cell cycle progression in murine breast cancer

Sildenafil Does Not Prevent Heart Hypertrophy and Fibrosis Induced by Cardiomyocyte Angiotensin II Type 1 Receptor Signaling.

Slack channels expressed in sensory neurons control neuropathic pain in mice

Stimulation of Slack K(+) Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex.

Targeted ablation of the Pde6h gene in mice reveals cross-species differences in cone and rod phototransduction protein isoform inventory.

The Na<sup>+</sup>-activated K<sup>+</sup> channel Slack contributes to synaptic development and plasticity

The role of cGMP-cGKI-signaling for duodenal bicarbonate secretion.

The role of cGMP-cGKI-signaling for duodenal bicarbonate secretion.

The sodium-activated potassium channel Slack is required for optimal cognitive flexibility in mice

Thrombocytosis as a response to high interleukin-6 levels in cGMP-dependent protein kinase I mutant mice.

Transdifferentiation of vascular smooth muscle cells to macrophage-like cells during atherogenesis

Turning on cGMP-dependent pathways to treat cardiac dysfunctions: boom, bust, and beyond.

[EXPRESS] Slack KNa Channels Influence Dorsal Horn Synapses and Nociceptive Behavior

cGKI signaling in cardiac hypertrophy.

cGMP kinase I regulates glucagon release

cGMP kinase I, cardiac hypertrophy and PDE inhibition.

cGMP regulated protein kinases (cGK).

cGMP-Elevating Compounds and Ischemic Conditioning Provide Cardioprotection Against Ischemia and Reperfusion Injury via Cardiomyocyte-Specific BK Channels