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List of works by Haruhiro Toko

Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes

scientific article

Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway

scientific article

Angiotensin II type 1a receptor is involved in cell infiltration, cytokine production, and neovascularization in infarcted myocardium

scientific article published on 12 February 2004

Angiotensin II type 1a receptor mediates doxorubicin-induced cardiomyopathy

scientific article published in July 2002

Angiotensin II type 1a receptor signals are involved in the progression of heart failure in MLP-deficient mice

scientific article

Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway

scientific article published on 3 May 2012

Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failure

scientific article published on 22 June 2009

Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure

scientific article published in Nature Communications

Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes

scientific article

Continuous blockade of L-type Ca2+ channels suppresses activation of calcineurin and development of cardiac hypertrophy in spontaneously hypertensive rats

scientific article

Critical roles of muscle-secreted angiogenic factors in therapeutic neovascularization.

scientific article

Csx/Nkx2-5 is required for homeostasis and survival of cardiac myocytes in the adult heart

scientific article

Cytokine therapy prevents left ventricular remodeling and dysfunction after myocardial infarction through neovascularization

scientific article published on 4 March 2004

Direct measurement of Ca2+ concentration in the SR of living cardiac myocytes

scientific article published in February 2004

Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents

scientific article published on 19 April 2010

Gene expression profile revealed different effects of angiotensin II receptor blockade and angiotensin-converting enzyme inhibitor on heart failure.

scientific article published in December 2003

Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling

scientific article published on 31 January 2018

Identification of MYLK3 mutations in familial dilated cardiomyopathy

scientific article published on 13 December 2017

Inhibitory molecules in signal transduction pathways of cardiac hypertrophy

scientific article

Leukemia inhibitory factor enhances survival of cardiomyocytes and induces regeneration of myocardium after myocardial infarction

scientific article published on 14 July 2003

Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II.

scientific article

Overexpression of P104L mutant caveolin-3 in mice develops hypertrophic cardiomyopathy with enhanced contractility in association with increased endothelial nitric oxide synthase activity

scientific article published on 25 November 2003

Pleiotropic effects of cytokines on acute myocardial infarction: G-CSF as a novel therapy for acute myocardial infarction

scientific article

Role of heat shock transcriptional factor 1 and heat shock proteins in cardiac hypertrophy

scientific article published on April 2008

Stretch-modulation of second messengers: effects on cardiomyocyte ion transport ⬇️

scientific article published on May 1, 2003

Upregulation of heat shock transcription factor 1 plays a critical role in adaptive cardiac hypertrophy

scientific article

p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload

scientific article published in Nature

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