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List of works by Yongkun Wei

A flow-proteometric platform for analyzing protein concentration (FAP): Proof of concept for quantification of PD-L1 protein in cells and tissues

scientific article published on 29 May 2018

ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway

scientific article

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.

scientific article

Aberrant Expression of proPTPRN2 in Cancer Cells Confers Resistance to Apoptosis

scientific article published on 15 April 2015

Actin cytoskeleton remodeling drives epithelial-mesenchymal transition for hepatoma invasion and metastasis

scientific article published on 23 November 2017

Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer

scientific article published on 29 March 2018

Author Correction: CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer

scientific article published on 29 January 2020

BAP1 links metabolic regulation of ferroptosis to tumour suppression

scientific article published on 10 September 2018

Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.

scientific article published on April 2008

Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors

scientific article published on 18 January 2016

Blocking immunosuppressive neutrophils deters pY696-EZH2-driven brain metastases

scientific article published on 01 May 2020

CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells

scientific article

CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer

scientific article published on 08 November 2019

CXCR4 expression in early breast cancer and risk of distant recurrence

scientific article published on 25 November 2009

Corrigendum: Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors

scientific article published in October 2016

Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer

scientific article

Cytoplasmic expression of p21CIP1/WAF1 is correlated with IKKbeta overexpression in human breast cancers

scientific article published on 01 November 2006

Definition of PKC-α, CDK6, and MET as therapeutic targets in triple-negative breast cancer

scientific article

Deubiquitylation and stabilization of PTEN by USP13

scientific article

Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer

scientific article published on August 2008

EGFR and c-MET Cooperate to Enhance Resistance to PARP Inhibitors in Hepatocellular Carcinoma

scientific article published on 20 December 2018

Endostatin-cytosine deaminase fusion protein suppresses tumor growth by targeting neovascular endothelial cells

scientific article published on January 2006

Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression

scientific article published on October 2007

Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth

scientific article published on 29 June 2018

GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers.

scientific article published on 02 August 2016

Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation.

scientific article published on 22 May 2014

Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation

scientific article published on 13 May 2021

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

scientific article

IKKbeta suppression of TSC1 function links the mTOR pathway with insulin resistance.

scientific article published on November 2008

IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression

scientific article published on 22 December 2011

IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion

scientific article published on 15 July 2019

Inhibition of CDK2 reduces EZH2 phosphorylation and reactivates ERα expression in high-grade serous ovarian carcinoma

scientific article published on 01 April 2020

JARID1D Is a Suppressor and Prognostic Marker of Prostate Cancer Invasion and Metastasis.

scientific article published on 08 January 2016

KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling.

scientific article

LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker

scientific article published on 23 September 2012

Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers

scientific article published on September 2008

MDM2 promotes cell motility and invasiveness by regulating E-cadherin degradation

scientific article

MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer

scientific article

Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer.

scientific article published on January 2005

Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer

scientific article published on July 2009

Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway

scientific article published on June 2005

Oncogenic Functions of Gli1 in Pancreatic Adenocarcinoma Are Supported by Its PRMT1-Mediated Methylation

scientific article published on 6 October 2016

PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression.

scientific article published on 6 February 2017

Palmitoylation stabilizes PD-L1 to promote breast tumor growth

scientific article published on 04 December 2018

Phosphorylation of EZH2 at T416 by CDK2 contributes to the malignancy of triple negative breast cancers.

scientific article

Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function

scientific article published in January 2018

Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy

scientific article published on 18 July 2019

TNFalpha induces HIF-1alpha expression through activation of IKKbeta

scientific article published on 17 September 2009

Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models

scientific article published on 01 July 2007

Targeting PKCδ as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer

scientific article published on 01 December 2018

The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer

scientific journal article

The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis

scientific article published on 08 April 2020

Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis.

scientific article published on November 2004

ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer ⬇️

scientific article published in April 2018

lncRNA directs cooperative epigenetic regulation downstream of chemokine signals

scientific article

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