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List of works by Hirohito Yamaguchi

AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation

scientific article published on 12 January 2016

Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells

scientific article

An essential role of PRMT1-mediated EGFR methylation in EGFR activation by ribonuclease 5

Author Correction: CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer

scientific article published on 29 January 2020

BikDD eliminates breast cancer initiating cells and synergizes with lapatinib for breast cancer treatment

scientific article

Blocking c-Met and EGFR reverses acquired resistance of PARP inhibitors in triple-negative breast cancer

scientific article published on 01 February 2020

Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors

scientific article published on 18 January 2016

CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer

scientific article published on 08 November 2019

COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport

scientific article

Carglumic acid promotes apoptosis and suppresses cancer cell proliferation in vitro and in vivo

scientific article published on 15 November 2015

Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells.

scientific article published on 23 January 2013

Corrigendum: Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors.

scientific article published in October 2016

Deubiquitination and Stabilization of PD-L1 by CSN5.

scientific article published on 14 November 2016

Dual targeting of tumor angiogenesis and chemotherapy by endostatin-cytosine deaminase-uracil phosphoribosyltransferase

scientific article

EGFR and c-MET Cooperate to Enhance Resistance to PARP Inhibitors in Hepatocellular Carcinoma

scientific article published on 20 December 2018

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

scientific article published on 20 January 2008

Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1

scientific article

Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1.

scientific article published in February 2018

Extracellular PKM2 induces cancer proliferation by activating the EGFR signaling pathway

scientific article published on 15 February 2016

FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization

scientific article published on 12 September 2011

GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers.

scientific article published on 02 August 2016

Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity.

scientific article published on 30 August 2016

High speed digital protein interaction analysis using microfluidic single molecule detection system

scientific article published on 24 May 2010

Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation

scientific article published on 13 May 2021

Interferon-inducible protein IFIXalpha inhibits cell invasion by upregulating the metastasis suppressor maspin

scientific article published on October 2008

MEASUREMENT of Protein 53 Diffusion Coefficient in Live HeLa Cells Using Raster Image Correlation Spectroscopy (RICS).

scientific article published on October 2010

MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1

scientific article published on 31 January 2019

Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2.

scientific article

Microfluidic three-dimensional hydrodynamic flow focusing for the rapid protein concentration analysis

scientific article

PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression.

scientific article published on 6 February 2017

PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response

scientific article published on 16 November 2015

Phosphorylation of EZH2 at T416 by CDK2 contributes to the malignancy of triple negative breast cancers.

scientific article

Pneumatically Actuated Soft Micromold Device for Fabricating Collagen and Matrigel Microparticles

scientific article published on 27 June 2017

Rapid detection of two-protein interaction with a single fluorophore by using a microfluidic device

scientific article

Regulation of ubiquitination-mediated protein degradation by survival kinases in cancer

scientific article

Targeting PKCδ as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer

scientific article published on 01 December 2018

Targeting the IKKβ/mTOR/VEGF signaling pathway as a potential therapeutic strategy for obesity-related breast cancer.

scientific article published on 23 July 2012

The potential role of YAP in Axl-mediated resistance to EGFR tyrosine kinase inhibitors

scientific article published on 01 December 2019

The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription.

scientific article

The translocon Sec61beta localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus

scientific article

mMAPS: a flow-proteometric technique to analyze protein-protein interactions in individual signaling complexes

scientific article

p53 acetylation is crucial for its transcription-independent proapoptotic functions

scientific article