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List of works by Laurie C Haws

A Framework for Systematic Evaluation and Quantitative Integration of Mechanistic Data in Assessments of Potential Human Carcinogens

scientific article published on 01 February 2019

A chronic oral reference dose for hexavalent chromium-induced intestinal cancer

scientific article

A high dose mode of action for tetrabromobisphenol A-induced uterine adenocarcinomas in Wistar Han rats: A critical evaluation of key events in an adverse outcome pathway framework

scientific article published on 28 January 2016

A review of background dioxin concentrations in urban/suburban and rural soils across the United States: implications for site assessments and the establishment of soil cleanup levels.

scientific article published on 15 August 2013

Addendum to: Evaluation of PCDD/F and dioxin-like PCB serum concentration data from the 2001-2002 National Health and Nutrition Examination Survey of the United States population

scientific article

Analysis and integration of developmental neurotoxicity and ancillary data into risk assessment: a case study of dimethoate

scientific article

Application of qualitative and quantitative uncertainty assessment tools in developing ranges of plausible toxicity values for 2,3,7,8-tetrachlorodibenzo-p-dioxin

scientific article published on 30 June 2019

Application of the U.S. EPA mode of action Framework for purposes of guiding future research: a case study involving the oral carcinogenicity of hexavalent chromium

scientific article (publication date: 2011)

Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis

scientific article

Assessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water.

scientific article published on 9 April 2013

Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: an in silico comparison with mutagenic and nonmutagenic carcinogens across tissues

scientific article published on 15 June 2012

Assessment of human health risks posed by consumption of fish from the Lower Passaic River, New Jersey

scientific article

Assessment of polybrominated diphenyl ether exposures and health risks associated with consumption of southern Mississippi catfish

scientific article published on 01 September 2008

Assessment of potential human health risks posed by benzene in beverages

scientific article published in May 2008

Assessment of the Mode of Action Underlying the Effects of GenX in Mouse Liver and Implications for Assessing Human Health Risks

scientific article published on 06 March 2020

Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans

scientific article

Comparison of Toxicity and Recovery in the Duodenum of B6C3F1 Mice Following Treatment with Intestinal Carcinogens Captan, Folpet, and Hexavalent Chromium

scientific article published in January 2017

Comparison of in vivo genotoxic and carcinogenic potency to augment mode of action analysis: Case study with hexavalent chromium.

scientific article published on 6 March 2016

Comparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: implications for carcinogenic modes of action.

scientific article published on 19 October 2011

Development of a chronic noncancer oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling

scientific article published on August 31, 2012

Development of a range of plausible non-cancer toxicity values for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) based on effects on sperm count: Application of systematic review methods and quantitative integration of dose response using metaregressio

scientific article published on 11 December 2020

Development of a refined database of mammalian relative potency estimates for dioxin-like compounds.

scientific article

Development of an oral reference dose for the perfluorinated compound GenX

scientific article published on 18 June 2019

Development of toxicity values and exposure estimates for tetrabromobisphenol A: application in a margin of exposure assessment.

scientific article published on 30 March 2015

Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron X-ray fluorescence microscopy.

scientific article published on 14 May 2015

Evaluation of PCDD/F and dioxin-like PCB serum concentration data from the 2001-2002 National Health and Nutrition Examination Survey of the United States population.

scientific article

Evaluation of impact of shale gas operations in the Barnett Shale region on volatile organic compounds in air and potential human health risks.

scientific article published on 25 September 2013

Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90days of exposure to hexavalent chromium in drinking water

scientific article published on December 2011

Hexavalent chromium reduction kinetics in rodent stomach contents

scientific article published on 08 June 2012

High concentrations of hexavalent chromium in drinking water alter iron homeostasis in F344 rats and B6C3F1 mice

scientific article published on 10 January 2014

High-Throughput Screening Data Interpretation in the Context of In Vivo Transcriptomic Responses to Oral Cr(VI) Exposure

scientific article

Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium.

scientific article published on 24 October 2017

Investigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium.

scientific article

Levels of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in southern Mississippi catfish and estimation of potential health risks.

scientific article published on 23 December 2008

Physiologically based pharmacokinetic model for humans orally exposed to chromium.

scientific article published on 17 April 2013

Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium.

scientific article published on 6 September 2012

Reduction of a large fish tissue analyte database: identifying and assessing data specific to a remediation site for risk assessment application.

scientific article

Reduction of hexavalent chromium by fasted and fed human gastric fluid. II. Ex vivo gastric reduction modeling

scientific article published on 7 July 2016

Risk of gastrointestinal disease associated with exposure to pathogens in the sediments of the Lower Passaic River

scientific article

Role of Risk of Bias in Systematic Review for Chemical Risk Assessment: A Case Study in Understanding the Relationship Between Congenital Heart Defects and Exposures to Trichloroethylene.

scientific article

Synchrotron-based imaging of chromium and γ-H2AX immunostaining in the duodenum following repeated exposure to Cr(VI) in drinking water

scientific article

Systematic evaluation of mechanistic data in assessing in utero exposures to trichloroethylene and development of congenital heart defects

scientific article published on 04 March 2020

Ten factors for considering the mode of action of Cr(VI)-induced gastrointestinal tumors in rodents

scientific article

The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds

scientific article

The importance of problem formulations in risk assessment: a case study involving dioxin-contaminated soil

scientific article

Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment.

scientific article