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List of works by Aleksandr Obikhod

Delayed chain termination protects the anti-hepatitis B virus drug entecavir from excision by HIV-1 reverse transcriptase

scientific article published on 20 October 2008

Engineering of a chimeric RB69 DNA polymerase sensitive to drugs targeting the cytomegalovirus enzyme

scientific article published on 21 July 2009

Evaluation of Single and Combination Therapies with Tenofovir Disoproxil Fumarate and Emtricitabine In Vitro and in a Robust Mouse Model Supporting High Levels of Hepatitis B Virus Replication ⬇️

scientific article published on September 17, 2012

Mechanism of Activation of -D-2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine and Inhibition of Hepatitis C Virus NS5B RNA Polymerase

scientific article (publication date: February 2007)

Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase

scientific article published on 09 June 2009

Pharmacokinetics of the anti-human immunodeficiency virus agent 1-(beta-D-dioxolane)thymine in rhesus monkeys

scientific article published on 7 May 2007

Short communication cellular pharmacology of 9-(beta-D-1,3-dioxolan-4-yl) guanine and its lack of drug interactions with zidovudine in primary human lymphocytes

scientific article published in January 2007

Simultaneous quantification of 9-(beta-D-1,3-dioxolan-4-yl)guanine, Amdoxovir and Zidovudine in human plasma by liquid chromatography-tandem mass spectrometric assay

scientific article published on 27 August 2009

Simultaneous quantification of intracellular natural and antiretroviral nucleosides and nucleotides by liquid chromatography-tandem mass spectrometry

scientific article published on March 2010

Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3'-azido-2',3'-dideoxyguanosine-5'-triphosphates as adenosine analogs ⬇️

scientific article published on September 13, 2011

Synthesis and Anti-HIV Evaluation of 3′-Triazolo Nucleosides ⬇️

scientific article published on April 1, 2011

Synthesis and evaluation of 3'-azido-2',3'-dideoxypurine nucleosides as inhibitors of human immunodeficiency virus

scientific article

Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3′-azido-2′,3′-dideoxypurine nucleosides ⬇️

scientific article published on May 30, 2011

Telbivudine exerts no antiviral activity against HIV-1 in vitro and in humans.

scientific article

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