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List of works by Emmanuelle di Tomaso

A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients

scientific article

AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

scientific article

Angiogenesis in brain tumours

scientific article published on August 2007

Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors.

scientific article

Antiangiogenic agents for the treatment of glioblastoma

scientific article published on December 2007

Combined vascular endothelial growth factor-targeted therapy and radiotherapy for rectal cancer: theory and clinical practice

scientific article published on October 2006

Complete pathological response to bevacizumab and chemoradiation in advanced rectal cancer

scientific article published on May 2007

Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy

scientific article published on March 2006

Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer

scientific article

Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer

scientific article published on 25 January 2004

Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice

scientific article

Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study

scientific article published on 26 May 2009

Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study

scientific article

Engineered blood vessel networks connect to host vasculature via wrapping-and-tapping anastomosis ⬇️

scientific article published on August 11, 2011

Exploratory analysis of early toxicity of sunitinib in advanced hepatocellular carcinoma patients: kinetics and potential biomarker value.

scientific article

Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape

scientific article

Hearing improvement after bevacizumab in patients with neurofibromatosis type 2

scientific article

Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications

scientific article published on August 2006

In vivo validation of MRI vessel caliber index measurement methods with intravital optical microscopy in a U87 mouse brain tumor model

scientific article

Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.

scientific article

Lymphatic metastasis in the absence of functional intratumor lymphatics

scientific article published on 25 April 2002

Merlin/NF2 Regulates Angiogenesis in Schwannomas through a Rac1/Semaphorin 3F-Dependent Mechanism ⬇️

scientific article published on February 1, 2012

Mosaic tumor vessels: cellular basis and ultrastructure of focal regions lacking endothelial cell markers

scientific article

PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment

scientific article

Pathology: cancer cells compress intratumour vessels.

scientific article

Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma

scientific article

Plasma soluble VEGFR-1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer

scientific article

Platelet-derived growth factor receptor-beta in Gorham's disease

scientific article published in December 2006

Responses to antiangiogenesis treatment of spontaneous autochthonous tumors and their isografts

scientific article published on 01 February 2003

Robust 3-D modeling of vasculature imagery using superellipsoids

scientific article published in February 2007

Safety, Efficacy, and Biomarker Exploration in a Phase II Study of Bevacizumab, Oxaliplatin, and Gemcitabine in Recurrent Müllerian Carcinoma ⬇️

scientific article published on June 1, 2011

Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients

scientific article published in November 2005

Tumour biology: herceptin acts as an anti-angiogenic cocktail

scientific article

VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer

scientific article

p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis

scientific article

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