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List of works by Carey Backus

BTBR ob/ob mice as a novel diabetic neuropathy model: Neurological characterization and gene expression analyses

scientific article published on 30 October 2014

Cell culture modeling to test therapies against hyperglycemia-mediated oxidative stress and injury.

scientific article published in November 2005

Cortical neurons develop insulin resistance and blunted Akt signaling: a potential mechanism contributing to enhanced ischemic injury in diabetes.

scientific article

Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis

scientific article published on 12 May 2020

Dietary reversal of neuropathy in a murine model of prediabetes and metabolic syndrome.

scientific article

Dual CCR2/CCR5 antagonist treatment attenuates adipose inflammation, but not microvascular complications in ob/ob mice

scientific article

Human neural stem cell transplantation into the corpus callosum of Alzheimer's mice

scientific article published on 18 August 2017

Hyperglycemia-induced tau cleavage in vitro and in vivo: a possible link between diabetes and Alzheimer's disease.

scientific article

Identification of candidate drugs for the treatment of ALS.

scientific article published in March 2005

Increased ratio of circulating neutrophils to monocytes in amyotrophic lateral sclerosis

scientific article published on June 2016

Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes.

scientific article published on 9 October 2009

Insulin Resistance Prevents AMPK-induced Tau Dephosphorylation through Akt-mediated Increase in AMPKSer-485 Phosphorylation

scientific article published on 22 June 2015

Intraspinal cord delivery of IGF-I mediated by adeno-associated virus 2 is neuroprotective in a rat model of familial ALS.

scientific article published on 24 December 2008

Juvenile murine models of prediabetes and type 2 diabetes develop neuropathy

scientific article published on 18 December 2018

Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice

scientific article

Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1

scientific article published on 08 May 2006

Mitochondrial DNA (mtDNA) biogenesis: visualization and duel incorporation of BrdU and EdU into newly synthesized mtDNA in vitro.

scientific article published on February 2010

Mitochondrial uncoupling has no effect on microvascular complications in type 2 diabetes

scientific article published in Scientific Reports

Mouse models of diabetic neuropathy

scientific article published on 31 July 2007

Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons.

scientific article

Receptor for Advanced Glycation End Products Activation Injures Primary Sensory Neurons via Oxidative Stress

scientific article published on 09 November 2006

SOD2 protects neurons from injury in cell culture and animal models of diabetic neuropathy

scientific article

Short-term hyperglycemia produces oxidative damage and apoptosis in neurons

scientific article

The Metabolic Syndrome and Microvascular Complications in a Murine Model of Type 2 Diabetes.

scientific article

The pleotrophic effects of insulin-like growth factor-I on human spinal cord neural progenitor cells.

scientific article published on 7 October 2010

Transcriptional profiling of diabetic neuropathy in the BKS db/db mouse: a model of type 2 diabetes.

scientific article

Two dynamin-2 genes are required for normal zebrafish development

scientific article