Search filters

List of works by Olga Zegarra-Moran

A minimal isoform of the TMEM16A protein associated with chloride channel activity.

scientific article published on 30 May 2011

A quantitative description of the activation and inhibition of CFTR by potentiators: Genistein.

scientific article published on July 2005

Alpha-aminoazaheterocyclic-methylglyoxal adducts do not inhibit cystic fibrosis transmembrane conductance regulator chloride channel activity.

scientific article published on 13 February 2008

Altered channel gating mechanism for CFTR inhibition by a high-affinity thiazolidinone blocker

scientific article published on January 2004

Antihypertensive 1,4-dihydropyridines as correctors of the cystic fibrosis transmembrane conductance regulator channel gating defect caused by cystic fibrosis mutations.

scientific article published on 8 September 2005

Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia.

scientific article

Block of CFTR-dependent chloride currents by inhibitors of multidrug resistance-associated proteins.

scientific article published on 3 February 2007

CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds

scientific article published on 21 March 2003

CFTR pharmacology.

scientific article

Ca2+-activated Cl- channels

scientific article published on October 2011

Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07.

scientific article

Direct interaction of a CFTR potentiator and a CFTR corrector with phospholipid bilayers

scientific article published on 26 April 2014

Double mechanism for apical tryptophan depletion in polarized human bronchial epithelium

scientific article

Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis mutations.

scientific article

Effect of inflammatory stimuli on airway ion transport.

scientific article

Epithelial sodium channel inhibition in primary human bronchial epithelia by transfected siRNA.

scientific article published on 21 August 2008

Epithelial sodium channel silencing as a strategy to correct the airway surface fluid deficit in cystic fibrosis

scientific article published in September 2013

Evaluation of a systems biology approach to identify pharmacological correctors of the mutant CFTR chloride channel

scientific article published on 10 March 2016

Evidence for direct CFTR inhibition by CFTR(inh)-172 based on Arg347 mutagenesis.

scientific article

Functional analysis of acid-activated Cl⁻ channels: properties and mechanisms of regulation.

scientific article published on January 2015

Functional and pharmacological induced structural changes of the cystic fibrosis transmembrane conductance regulator in the membrane solved using SAXS.

scientific article published on 2 October 2014

Functional human CFTR produced by a stable minichromosome

scientific article published on 16 August 2002

Gelsolin Secretion in Interleukin-4–treated Bronchial Epithelia and in Asthmatic Airways

scientific article published on 11 August 2005

High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening

scientific article published on 2 August 2002

High-throughput screening of libraries of compounds to identify CFTR modulators.

scientific article

IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro

scientific article published on 01 January 2002

In vitro recapitulation of the site-specific editing (to wild-type) of mutant IDS mRNA transcripts, and the characterization of IDS protein translated from the edited mRNAs

scientific article

Lectin conjugates as potent, nonabsorbable CFTR inhibitors for reducing intestinal fluid secretion in cholera.

scientific article published on 7 February 2007

Modulation of cystic fibrosis transmembrane conductance regulator (CFTR) activity and genistein binding by cytosolic pH.

scientific article published on 25 October 2010

Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators.

scientific article published on 02 June 2009

Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazides

scientific article published in July 2008

On the measurement of the functional properties of the CFTR.

scientific article published on 25 September 2008

Pharmacological analysis of epithelial chloride secretion mechanisms in adult murine airways.

scientific article published on 7 April 2016

Pharmacological rescue of mutant CFTR protein improves the viscoelastic properties of CF mucus.

scientific article published on 8 December 2015

Pharmacological therapy for cystic fibrosis: from bench to bedside

scientific article published on June 2011

Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating

scientific article

Proteomic analysis of the airway surface liquid: modulation by proinflammatory cytokines

article

Regulation of TMEM16A chloride channel properties by alternative splicing

scientific article

Rheological Properties of Cystic Fibrosis Bronchial Secretion and in Vitro Drug Permeation Study: The Effect of Sodium Bicarbonate

scientific article

Small molecule anionophores promote transmembrane anion permeation matching CFTR activity

scientific article published on 8 February 2018

Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening.

scientific article

Structure of wild type and mutant F508del CFTR: A small-angle X-ray scattering study of the protein-detergent complexes.

scientific article published on 2 February 2016

Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.

scientific article published on 28 May 2015

TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity

scientific article

Thiocyanate transport in resting and IL-4-stimulated human bronchial epithelial cells: role of pendrin and anion channels

scientific article

Paulina is supported by:

About Paulina

Help