List of works by Joseph E. Italiano

A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site

scientific article

A role for Rab27b in NF-E2-dependent pathways of platelet formation

scientific article published on 07 August 2003

A secreted tyrosine kinase acts in the extracellular environment

scientific article

ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells

scientific article

Abnormal megakaryopoiesis and platelet function in cyclooxygenase-2-deficient mice

scientific article

Altered microtubule equilibrium and impaired thrombus stability in mice lacking RanBP10.

scientific article published on 30 August 2012

Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially released

scientific article

Animating platelet production adds physiological context

scientific article published on 14 August 2013

Anti-apoptotic BCL2L2 increases megakaryocyte proplatelet formation in cultures of human cord blood

scientific article published on 07 February 2019

Anticoagulation inhibits tumor cell-mediated release of platelet angiogenic proteins and diminishes platelet angiogenic response.

scientific article published on 24 September 2013

Aspirin inhibits platelets from reprogramming breast tumor cells and promoting metastasis

scientific article published on 01 January 2019

CCL5 derived from platelets increases megakaryocyte proplatelet formation

scientific article published on 8 December 2015

Canonical Wnt signaling in megakaryocytes regulates proplatelet formation

scientific article published on 16 November 2012

Clinical relevance of microparticles from platelets and megakaryocytes

scientific article

Contributors

Cytoskeletal mechanics of proplatelet maturation and platelet release.

scientific article

Cytoskeletal mechanisms for platelet production.

scientific article

Cytoskeletal perturbation leads to platelet dysfunction and thrombocytopenia in variant forms of Glanzmann thrombasthenia

scientific article

DREAM plays an important role in platelet activation and thrombogenesis

scientific article

Deletion of the Arp2/3 complex in megakaryocytes leads to microthrombocytopenia in mice

scientific article published on 01 August 2017

Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis

scientific article

Developmental Stage-Specific Manifestations of Absent TPO/c-MPL Signalling in Newborn Mice

scientific article published on 6 December 2017

Developmental differences in megakaryocytopoiesis are associated with up-regulated TPO signaling through mTOR and elevated GATA-1 levels in neonatal megakaryocytes

scientific article

Differential roles of cAMP and cGMP in megakaryocyte maturation and platelet biogenesis

scientific article published on 11 September 2012

Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes

scientific article

Direct visualization of the endomitotic cell cycle in living megakaryocytes: differential patterns in low and high ploidy cells

scientific article

Does size matter in platelet production?

scientific article

Dynamic Visualization of Thrombopoiesis Within Bone Marrow

scientific article published in Science

Dynamin 3 participates in the growth and development of megakaryocytes

scientific article published on December 2008

Dynamin-related protein-1 controls fusion pore dynamics during platelet granule exocytosis

scientific article

Elevated release of sCD40L from platelets of diabetic patients by thrombin, glucose and advanced glycation end products

scientific article published in May 2005

Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan

scientific article

High Content, Label-Free Analysis of Proplatelet Production from Megakaryocytes

scientific article published on 14 July 2020

High-content live-cell imaging assay used to establish mechanism of trastuzumab emtansine (T-DM1)--mediated inhibition of platelet production

scientific article

IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs

scientific article

Importance of free actin filament barbed ends for Arp2/3 complex function in platelets and fibroblasts.

scientific article

Inducible Gata1 suppression expands megakaryocyte-erythroid progenitors from embryonic stem cells

scientific article

Interactions between the megakaryocyte/platelet-specific beta1 tubulin and the secretory leukocyte protease inhibitor SLPI suggest a role for regulated proteolysis in platelet functions

scientific article published on 17 August 2004

Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation

scientific article

Junín virus infection of human hematopoietic progenitors impairs in vitro proplatelet formation and platelet release via a bystander effect involving type I IFN signaling.

scientific article

Lysyl oxidase is associated with increased thrombosis and platelet reactivity.

scientific article published on 11 January 2016

Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4.

scientific article published on 10 October 2013

Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets

scientific article published on 08 September 2017

Mechanisms and implications of platelet discoid shape

scientific article

Mechanisms of organelle transport and capture along proplatelets during platelet production

scientific article

Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets

scientific article published on 01 May 2019

Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles

scientific article

Megakaryocytes compensate for Kit insufficiency in murine arthritis.

scientific article

Megakaryocytes package contents into separate α-granules that are differentially distributed in platelets ⬇️

scientific article published on 01 October 2019

Microtubule and cortical forces determine platelet size during vascular platelet production

scientific article

Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein

scientific article

Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis by multiple pathways including activation of RhoA, cathepsin B, and cAMP-response element-binding protein

scientific article published on 29 November 2012

Normal ranges of angiogenesis regulatory proteins in human platelets

scientific article published on 01 July 2010

Platelet Activation via Shear Stress Exposure Induces a Differing Pattern of Biomarkers of Activation versus Biochemical Agonists

scientific article published on 05 May 2020

Platelet Dysfunction and Thrombosis in JAK2V617F-Mutated Primary Myelofibrotic Mice

scientific article published on 20 August 2020

Platelet alloantibody detection: moving ahead

scientific article published on 01 November 2019

Platelet bioreactor-on-a-chip

scientific article

Platelet formation

scientific article

Platelet- and megakaryocyte-derived microparticles

scientific article

Platelet-associated PF-4 as a biomarker of early tumor growth

scientific article

Platelet-derived extracellular vesicles infiltrate and modify the bone marrow during inflammation

scientific article published on 01 July 2020

Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis

scientific article

Platelets Lacking Sialic Acid Clear Rapidly from the Circulation Due to Ingestion by Asialoglycoprotein Receptor-Expressing Liver Macrophages and Hepatocytes

scientific article

Platelets actively sequester angiogenesis regulators

scientific article

Platelets and the immune continuum

scientific article published on April 2011

Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice

scientific article

Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration.

scientific article published on 31 January 2018

Platelets: production, morphology and ultrastructure

scientific article published on January 2012

Preface

Proteasome function is required for platelet production

scientific article (publication date: September 2014)

RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules

scientific journal article

Release of angiogenesis regulatory proteins from platelet alpha granules: modulation of physiologic and pathologic angiogenesis

scientific article

Role for phosphoinositide 3-kinase in Fc gamma RIIA-induced platelet shape change

scientific article

Role of Epac1, an exchange factor for Rap GTPases, in endothelial microtubule dynamics and barrier function

scientific article

Scalable generation of universal platelets from human induced pluripotent stem cells.

scientific article published on 16 October 2014

Selinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis

scientific article

Sniffing out the aroma(tase) of drug-induced thrombocytopenia

scientific article published on 01 June 2020

Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation.

scientific article

T granules in human platelets function in TLR9 organization and signaling

scientific article

Tamoxifen Directly Inhibits Platelet Angiogenic Potential and Platelet-Mediated Metastasis

scientific article published on 2 February 2017

The biogenesis of platelets from megakaryocyte proplatelets

scientific article

The identification and characterization of zebrafish hematopoietic stem cells

scientific article

The incredible journey: From megakaryocyte development to platelet formation.

scientific article

The microtubule plus-end tracking protein CLASP2 is required for hematopoiesis and hematopoietic stem cell maintenance

scientific article

The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia

scientific article

The origin and function of platelet glycosyltransferases

scientific article

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation

scientific article

Unlocking the Molecular Secrete(s) of α-Granule Biogenesis

scientific article published on 01 November 2018

Unraveling mechanisms that control platelet production

scientific article

VEGF, PF4 and PDGF are elevated in platelets of colorectal cancer patients

scientific article published on 09 March 2012

Visualization and manipulation of the platelet and megakaryocyte cytoskeleton

scientific article published on 01 January 2012

Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules

scientific article

vWF maturation and release are controlled by two regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2

scientific article published on 02 July 2020

α-Adducin dissociates from F-actin and spectrin during platelet activation ⬇️

scientific article published on May 12, 2003

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