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List of works by Jane E. Freedman

A Translational Model for Venous Thromboembolism: MicroRNA Expression in Hibernating Black Bears

scientific article published on 25 August 2020

A platelet transcriptome revolution

scientific article published on 01 October 2011

A statement on ethics from the HEART Group

scientific article

Abciximab pharmacodynamic model with neural networks used to integrate sources of patient variability

scientific article published on January 2004

Age-associated microRNA expression in human peripheral blood is associated with all-cause mortality and age-related traits.

scientific article published on 17 October 2017

Aspirin resistance and atherothrombotic disease

scientific article (publication date: 20 September 2005)

Aspirin resistance in atherosclerosis

scientific article published on April 2008

Aspirin resistance: current concepts

scientific article (publication date: 2004)

Associations of Circulating Extracellular RNAs With Myocardial Remodeling and Heart Failure

scientific article published on 01 September 2018

Atrial fibrillation and stroke prevention in aging patients: what's good can be even better

scientific article published on 03 June 2014

Atrial natriuretic peptide is negatively regulated by microRNA-425.

scientific article published on 15 July 2013

Blood and cardiovascular disease: the promise and limitations of gene expression analysis

scientific article published on 01 October 2008

Blood-Derived Extracellular RNA and Platelet Pathobiology: Adding Pieces to a Complex Circulating Puzzle

scientific article

CD40 ligand influences platelet release of reactive oxygen intermediates

scientific article published on 01 September 2005

CD40 ligand--assessing risk instead of damage?

scientific article published on 01 March 2003

CD40-40L signaling in vascular inflammation

scientific article published on 25 April 2007

CD40-CD40 ligand interactions in oxidative stress, inflammation and vascular disease

scientific article published on 30 October 2008

CD40-CD40L and platelet function: beyond hemostasis

scientific article published on 01 May 2003

Cardiovascular devices and platelet interactions: understanding the role of injury, flow, and cellular responses

scientific article published on April 2012

Challenges and Opportunities in Linking Long Noncoding RNAs to Cardiovascular, Lung, and Blood Diseases

scientific article published on 17 November 2016

Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction

scientific article published on 14 September 2015

Circulating Cell and Plasma microRNA Profiles Differ between Non-ST-Segment and ST-Segment-Elevation Myocardial Infarction

scientific article published on October 2013

Circulating Extracellular Vesicles in Human Disease

scientific article published on 01 September 2018

Circulating Extracellular Vesicles in Human Disease

scientific article published on 01 November 2018

Circulating Platelets as Mediators of Immunity, Inflammation, and Thrombosis

scientific article published in January 2018

Circulating extracellular RNAs, myocardial remodeling, and heart failure in patients with acute coronary syndrome

scientific article published on 08 June 2019

Circulating microRNAs miR-331 and miR-195 differentiate local luminal a from metastatic breast cancer

scientific article published on 10 May 2019

Circulation Research

scientific article published on 20 June 2019

Clopidogrel, genetics, and drug responsiveness

scientific article published in January 2009

Comparison of RNA isolation and associated methods for extracellular RNA detection by high-throughput quantitative polymerase chain reaction

scholarly article by Kahraman Tanriverdi published in May 2016

Compensatory mechanisms influence hemostasis in setting of eNOS deficiency

scientific article published on 24 November 2004

Comprehensive Metabolic Phenotyping Refines Cardiovascular Risk in Young Adults

scientific article published on 19 October 2020

Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling

scientific article published on 16 July 2018

Corrigendum: Diverse human extracellular RNAs are widely detected in human plasma

scientific article published on 3 June 2016

Decreased thromboembolic stroke but not atherosclerosis or vascular remodelling in mice with ROCK2-deficient platelets

scientific article published on 14 April 2017

Defining miRNA targets: balancing simplicity with complexity

scientific article published on 26 April 2013

Dipyridamole, cerebrovascular disease, and the vasculature

scientific article published on 15 February 2008

Discordant Expression of Circulating microRNA from Cellular and Extracellular Sources

scientific article

Dissecting the roles of microRNAs in coronary heart disease via integrative genomic analyses

scientific article

Distinct gene signatures in aortic tissue from ApoE-/- mice exposed to pathogens or Western diet.

scientific article

Diverse human extracellular RNAs are widely detected in human plasma.

scientific article published on 26 April 2016

Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits

scientific article published on 8 March 2017

Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits

scientific article published in June 2017

Effects of endothelial nitric oxide synthase gene polymorphisms on platelet function, nitric oxide release, and interactions with estradiol

scientific article published in July 2002

Erratum: Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling

scientific article published on 01 September 2018

Extracellular RNAs Are Associated With Insulin Resistance and Metabolic Phenotypes

scientific article published on 9 February 2017

Extracellular RNAs: development as biomarkers of human disease

scientific article

Facts and controversies of aspirin and clopidogrel therapy

scientific article published on March 2009

Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes

scientific article published on 20 September 2013

Genome-wide identification of microRNA expression quantitative trait loci

scientific article

Glycoprotein IIb/IIIa inhibition enhances platelet nitric oxide release.

scientific article

Grape seed and skin extracts inhibit platelet function and release of reactive oxygen intermediates

scientific article

Hepatic steatosis is associated with cardiometabolic risk in a rural Indian population: A prospective cohort study

Heritability, platelet function, and aspirin: a link established but cause unknown

scientific article (publication date: 15 May 2007)

High-fat diets and cardiovascular disease: are nutritional supplements useful?

scientific article (publication date: 21 May 2003)

Hypoxia influences CD40-CD40L mediated inflammation in endothelial and monocytic cells.

scientific article

Ideal Cardiovascular Health, Cardiovascular Remodeling, and Heart Failure in Blacks: The Jackson Heart Study.

scientific article published on February 2017

Immune versus thrombotic stimulation of platelets differentially regulates signalling pathways, intracellular protein-protein interactions, and alpha-granule release

scientific article

Inducible Toll-like receptor and NF-kappaB regulatory pathway expression in human adipose tissue

scientific article published on 21 February 2008

Inflammation & the platelet histone trap ⬇️

scientific article published on August 18, 2011

Inherited dysfunctional nitric oxide signaling and the pathobiology of atherothrombotic disease

scientific article

Innate immunity and toll-like receptor antagonists: a potential role in the treatment of cardiovascular diseases

scientific article published on January 2009

Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies

scientific article

Interleukin 1 receptor 1 and interleukin 1β regulate megakaryocyte maturation, platelet activation, and transcript profile during inflammation in mice and humans

scientific article

M118, a novel low-molecular weight heparin with decreased polydispersity leads to enhanced anticoagulant activity and thrombotic occlusion in ApoE knockout mice

scientific article

Medication errors in acute cardiac care: An American Heart Association scientific statement from the Council on Clinical Cardiology Subcommittee on Acute Cardiac Care, Council on Cardiopulmonary and Critical Care, Council on Cardiovascular Nursing,

scientific article published on 01 November 2002

Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium

scientific article

Messenger RNA and MicroRNA transcriptomic signatures of cardiometabolic risk factors

scientific article

Micro RNAs from DNA Viruses are Found Widely in Plasma in a Large Observational Human Population

scientific article

Micro-RNAs Are Related to Epicardial Adipose Tissue in Participants With Atrial Fibrillation: Data From the MiRhythm Study

scientific article published on 14 August 2019

MicroRNAs in platelet function and cardiovascular disease

scientific article published on 07 July 2015

Microdeletion syndromes disclose replication timing alterations of genes unrelated to the missing DNA.

scientific article published on 14 March 2009

Molecular Signature of Multisystem Cardiometabolic Stress and Its Association With Prognosis

scientific article published on 22 July 2020

Molecular regulation of platelet-dependent thrombosis

scientific article published in October 2005

Neutrophil CD40 enhances platelet-mediated inflammation

scientific article

New paradigms in thrombosis: novel mediators and biomarkers platelet RNA transfer

scientific article published on January 2014

New therapies for stroke prevention in atrial fibrillation: the long road to enhanced efficacy

scientific article published on 8 September 2009

Nitrated lipids: defining their bioactivity

scientific article

Noncoding RNAs in Cardiovascular Disease: Current Knowledge, Tools and Technologies for Investigation, and Future Directions: A Scientific Statement From the American Heart Association

scientific article published on 29 June 2020

Nuts, Cardiovascular Health, and Diabetes

scientific article published on 01 March 2019

Oxidative stress and platelets

scientific article published on 03 January 2008

Peer Review Practices for Evaluating Biomedical Research Grants: A Scientific Statement From the American Heart Association

scientific article published on 06 July 2017

Pharmacodynamic profile of short-term readministration of abciximab in healthy subjects ⬇️

scientific article published on 01 January 2002

Pharmacodynamics of abciximab during angioplasty: comparison to healthy subjects

scientific article published on 01 March 2002

Plasma Circulating Extracellular RNAs in Left Ventricular Remodeling Post-Myocardial Infarction

scientific article published on 18 May 2018

Plasma, serum, and platelet expression of CD40 ligand in adults with cardiovascular disease

scientific article published on 19 September 2005

Platelet functional and transcriptional changes induced by intralipid infusion

Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis

scientific article

Platelet-monocyte aggregates: bridging thrombosis and inflammation

scientific article published on 01 May 2002

Platelets and COVID-19: Inflammation, Hyperactivation and Additional Questions

scientific article published on 05 November 2020

Platelets and Immunity: Going Viral

scientific article published on 24 June 2020

Platelets and platelet-like particles mediate intercellular RNA transfer ⬇️

scientific article published on May 17, 2012

Platelets: developmental biology, physiology, and translatable platforms for preclinical investigation and drug development.

scientific article published on June 2008

Pollen-derived RNAs Are Found in the Human Circulation

scientific article published on 24 August 2019

Promoting ethical conduct in the publication of research

scientific article published in January 2008

Proteins Altered by Surgical Weight Loss Highlight Biomarkers of Insulin Resistance in the Community

scholarly article by Ravi V. Shah et al published January 2019 in Arteriosclerosis, Thrombosis, and Vascular Biology

Redox state of dipyridamole is a critical determinant for its beneficial antioxidant and antiinflammatory effects

scientific article published in October 2007

Reduced adipose tissue inflammation represents an intermediate cardiometabolic phenotype in obesity

scientific article

Regulation of endogenous reactive oxygen species in platelets can reverse aggregation

scientific article published on 6 November 2003

Regulatory effects of TLR2 on megakaryocytic cell function ⬇️

scientific article published on March 31, 2011

Relationship among circulating inflammatory proteins, platelet gene expression, and cardiovascular risk

scientific article

Relationship between markers of platelet activation and inflammation with disease activity in Wegener's granulomatosis.

scientific article published on 16 March 2011

Resistance training: does it alter lytic potential?

scientific article published on 01 March 2006

Review: Nutriceuticals as antithrombotic agents

scientific article published on 14 June 2010

SARS-CoV-2 Initiates Programmed Cell Death in Platelets

SARS-CoV-2 Receptors are Expressed on Human Platelets and the Effect of Aspirin on Clinical Outcomes in COVID-19 Patients

scientific article published on 23 December 2020

Sex differences in platelet toll-like receptors and their association with cardiovascular risk factors

scientific article

Sex- and age-interacting eQTLs in human complex diseases

scientific article

Sexual and gender-based violence against refugee women: a hidden aspect of the refugee "crisis".

scientific article

Small RNA-seq during acute maximal exercise reveal RNAs involved in vascular inflammation and cardiometabolic health: brief report

scientific article published on 15 September 2017

Specific Inflammatory Stimuli Lead to Distinct Platelet Responses in Mice and Humans

scientific article published on 6 July 2015

Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase

scientific article published on 23 December 2008

Stroke and Circulating Extracellular RNAs

scientific article published on 13 March 2017

Subclinical Atherosclerosis, Statin Eligibility, and Outcomes in African American Individuals: The Jackson Heart Study

scientific article

The Adverse Vascular Effects of E-Cigarettes: Smoke Without the Fire

scientific article published on 01 June 2019

The Antiinflammatory Effects of Purple Grape Juice Consumption in Subjects with Stable Coronary Artery Disease

scientific article published on 01 November 2004

The Dynamic Platelet Transcriptome in Obesity and Weight Loss

scientific article published on 10 December 2020

The aspirin resistance controversy: clinical entity or platelet heterogeneity?

scientific article (publication date: 27 June 2006)

The clinician as investigator: participating in clinical trials in the practice setting

scientific article published on June 2004

The clinician as investigator: participating in clinical trials in the practice setting: Appendix 1: fundamentals of study design

scientific article published on June 2004

The clinician as investigator: participating in clinical trials in the practice setting: Appendix 2: statistical concepts in study design and analysis

scientific article published on June 2004

The distribution of circulating microRNA and their relation to coronary disease

scientific article

The effect of dipyridamole on vascular cell-derived reactive oxygen species

scientific article published on 26 July 2005

The effects of tamoxifen and its metabolites on platelet function and release of reactive oxygen intermediates

scientific article published on 27 October 2004

The many antithrombotic actions of nitric oxide

scientific article published on October 2006

The role of CD40L and VEGF in the modulation of angiogenesis and inflammation

scientific article published on 23 May 2010

The role of RNA uptake in platelet heterogeneity

scientific article published on 9 March 2017

The role of inflammation in regulating platelet production and function: Toll-like receptors in platelets and megakaryocytes

scientific article

The role of the blood transcriptome in innate inflammation and stroke ⬇️

scientific article published on October 1, 2010

Thrombosis and platelets: an update

scientific article published on 30 December 2016

Transcriptomics: new targets for diagnosing and treating cardiovascular disease

scientific article published on 01 January 2008

Transitions in Metabolic Risk and Long-Term Cardiovascular Health: Coronary Artery Risk Development in Young Adults (CARDIA) Study.

scientific article published on 13 October 2016

Translational Epidemiology: Entering a Brave New World of Team Science

scientific article

Unique Circulating MicroRNA Profiles in HIV Infection

scientific article published on 01 December 2018

Use of Genetics and Transcriptomics in the Diagnosis and Treatment of Coronary Artery Disease ⬇️

scientific article published on October 1, 2010

Whole blood microRNA expression associated with stroke: Results from the Framingham Heart Study

scientific article published on 08 August 2019

[Antiplatelet and anticoagulant therapy for stroke prevention in patients with non-valvular atrial fibrillation: evidence based strategies and new developments]

scientific article published on 15 March 2011

p38: signaling improved platelet storage?

scientific article published on 01 March 2010

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