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List of works by Andrew D. Johnson

70-year legacy of the Framingham Heart Study

scientific article published on 01 November 2019

<i>ZBTB33</i> is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing

scientific article published on 14 July 2021

A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling

scientific article published on 04 July 2020

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation

scientific article

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology

scientific article published on 14 January 2019

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

A large-scale exome array analysis of venous thromboembolism

scientific article published on 19 January 2019

A meta-analysis of gene expression signatures of blood pressure and hypertension

scientific article (publication date: March 2015)

A systematic heritability analysis of the human whole blood transcriptome

scientific article

A systems biology framework identifies molecular underpinnings of coronary heart disease

scientific article published on 28 March 2013

ADP Platelet Hyperreactivity Predicts Cardiovascular Disease in the FHS (Framingham Heart Study).

scientific article published on 3 March 2018

Actionable exomic incidental findings in 6503 participants: challenges of variant classification

scientific article

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

scientific article published on 31 May 2017

An open access database of genome-wide association results

scholarly article by Andrew D Johnson & Christopher J O'Donnell published 22 January 2009 in BMC Medical Genetics

Analysis commons, a team approach to discovery in a big-data environment for genetic epidemiology

scientific article published in October 2017

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

scientific article

Association of genetic variation in the mitochondrial genome with blood pressure and metabolic traits

scientific article published on 04 September 2012

Association of genomic loci from a cardiovascular gene SNP array with fibrinogen levels in European Americans and African-Americans from six cohort studies: the Candidate Gene Association Resource (CARe).

scientific article

Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals

scientific article

Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article (publication date: June 2014)

Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts

scientific article published on April 2009

Association of single nucleotide polymorphisms on chromosome 9p21.3 with platelet reactivity: a potential mechanism for increased vascular disease

scientific article

Author Correction: Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease

scientific article published in Nature Communications

CLIA-tested genetic variants on commercial SNP arrays: potential for incidental findings in genome-wide association studies

scientific article

CUBN is a gene locus for albuminuria

scientific article

Caenorhabditis elegans orthologs of human genes differentially expressed with age are enriched for determinants of longevity

scientific article published on 12 April 2017

Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease

scientific article

Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction

scientific article published on 14 September 2015

Clinical and genetic correlates of growth differentiation factor 15 in the community

scientific article

Clonal hematopoiesis associated with epigenetic aging and clinical outcomes

scientific article published on 29 May 2021

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases

scientific article

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

scientific article

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

scientific article

Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling

scientific article published on 03 September 2013

Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium

scientific article published on 8 November 2011

Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels

scientific article

Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection.

scientific article

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: The complex genetics of gait speed: genome-wide meta-analysis approach

scientific article published on 7 July 2017

Corrigendum: Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.

scientific article

D-Dimer in African Americans: Whole Genome Sequence Analysis and Relationship to Cardiovascular Disease Risk in the Jackson Heart Study

scientific article published on 14 September 2017

DNA methylation age is associated with an altered hemostatic profile in a multi-ethnic meta-analysis

article

DNA mismatch repair gene MSH6 implicated in determining age at natural menopause

scientific article published on 19 December 2013

De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population

scientific article published on 21 January 2020

Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study

scientific article

Dissecting the roles of microRNAs in coronary heart disease via integrative genomic analyses

scientific article

Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits

scientific article published on 8 March 2017

Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits

scientific article published in June 2017

Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations

scientific article

Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies

scientific article published on 10 January 2019

Erratum: Whole-genome sequence-based analysis of thyroid function

scientific article published on 20 May 2015

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

scientific article

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

scientific article

Exome-chip meta-analysis identifies association between variation in ANKRD26 and platelet aggregation

scientific article

Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms

scientific article published on 22 May 2017

Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies

scientific article

GRASP v2.0: an update on the Genome-Wide Repository of Associations between SNPs and phenotypes

scientific article

GRASP: analysis of genotype-phenotype results from 1390 genome-wide association studies and corresponding open access database

scientific article (publication date: 15 June 2014)

GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium

scientific article

Gene expression analysis of whole blood, peripheral blood mononuclear cells, and lymphoblastoid cell lines from the Framingham Heart Study

scientific article published on November 2011

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

scientific article

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

scientific article published on 20 February 2014

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

scientific article

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

scholarly article published 28 August 2017

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic architecture of subcortical brain structures in 38,851 individuals

scientific article published on 21 October 2019

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

scientific article

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease

scientific article

Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes

scientific article published on 20 September 2013

Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies

scientific article published on 23 January 2016

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

Genome-wide Association Study Of Plasma Proteins Identifies Putatively Causal Genes, Proteins, And Pathways For Cardiovascular Disease

article

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

scientific article published on 19 December 2016

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations

scientific article

Genome-wide association and functional follow-up reveals new loci for kidney function

scientific article

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women

scientific article

Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology

scientific article

Genome-wide association meta-analysis for total serum bilirubin levels

scientific article

Genome-wide association of pericardial fat identifies a unique locus for ectopic fat

scientific article

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

scientific article

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

scientific article

Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction

scientific article

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide association study of blood pressure and hypertension

scientific journal article

Genome-wide association study of kidney function decline in individuals of European descent

scientific article

Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease

scientific article published on 19 September 2019

Genome-wide identification of microRNA expression quantitative trait loci

scientific article

Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease

scientific article published in Nature Communications

Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists

scientific article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake

scientific article

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Genome-wide transcriptome study using deep RNA sequencing for myocardial infarction and coronary artery calcification

scientific article published on 10 February 2021

Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism

scientific article published on 01 November 2019

HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype

scientific article published on 28 October 2019

Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression

scientific article

Identification of common genetic variants controlling transcript isoform variation in human whole blood

scientific article published on 16 February 2015

Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program

scientific article published on 26 September 2019

Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project.

scientific article

Incorporating biological knowledge in the search for gene x gene interaction in genome-wide association studies.

scientific article

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

scientific article published on 14 October 2020

Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies

scientific article

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

scientific article published on 8 September 2012

Integrative DNA, RNA, and protein evidence connects TREML4 to coronary artery calcification

scientific article

Integrative Genomic Analysis Reveals Four Protein Biomarkers for Platelet Traits

scientific article published on 12 August 2020

Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.

scientific article

Integrative network analysis reveals molecular mechanisms of blood pressure regulation

scientific article published on January 2015

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

scientific article

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

scientific article published in December 2015

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array

scientific article

Loci influencing blood pressure identified using a cardiovascular gene-centric array

scientific article published on 8 January 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

scientific article

Mean platelet volume - A controversial marker of platelets that requires further unpacking

scientific article published on 14 March 2017

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

scientific article published on 10 May 2019

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci ⬇️

scientific article

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

scientific article

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018

Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation

scientific article published on 05 December 2016

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

scientific article (publication date: 17 September 2013)

Multi‐phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations

scientific article published in 2022

New loci associated with kidney function and chronic kidney disease

scientific article

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Novel Thrombotic Function of a Human SNP in STXBP5 Revealed by CRISPR/Cas9 Gene Editing in Mice

scientific article published on 29 December 2016

Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium

scientific article

PRIMe: a method for characterization and evaluation of pleiotropic regions from multiple genome-wide association studies ⬇️

scientific article published on March 12, 2011

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

scientific article

Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations

scientific article

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

scientific article

Platelet Measurements and Type 2 Diabetes: Investigations in Two Population-Based Cohorts

scientific article published on 10 July 2020

Platelet Reactivity in Individuals Over 65 Years Old Is not Modulated by Age

scientific article published on 27 April 2020

Platelet function as a risk factor for venous thromboembolism in the Framingham Heart Study

scientific article published on 25 January 2017

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

scientific article

Pleiotropic genes for metabolic syndrome and inflammation

scientific article

Population genomic analysis of 962 whole genome sequences of humans reveals natural selection in non-coding regions.

scientific article

Prediction of Causal Candidate Genes in Coronary Artery Disease Loci

scientific article

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 01 July 2019

Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset

scientific article

Rare coding variants pinpoint genes that control human hematological traits

scientific article published on 7 August 2017

Relation of platelet and leukocyte inflammatory transcripts to body mass index in the Framingham heart study

scientific article

Replication and hematological characterization of human platelet reactivity genetic associations in men from the Caerphilly Prospective Study (CaPS).

scientific article published on 30 October 2015

Resequencing and clinical associations of the 9p21.3 region: a comprehensive investigation in the Framingham heart study

scientific article published on 11 January 2013

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

scientific article published on 6 March 2019

Sex- and age-interacting eQTLs in human complex diseases

scientific article

Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies

scientific article

Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

scientific article

Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion.

scientific article

Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs

scientific article

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease ⬇️

scientific article published on February 2017

Temporal Trends in Results Availability from Genome-Wide Association Studies ⬇️

scientific article (publication date: September 2011)

The Polygenic and Monogenic Basis of Blood Traits and Diseases

scientific article published on 01 September 2020

The complex genetics of gait speed: genome-wide meta-analysis approach

scientific article published on 10 January 2017

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The genetics of platelet count and volume in humans.

scientific article

The transcriptional landscape of age in human peripheral blood

scientific article

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

scientific article

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

scientific article

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

scientific article published on 01 September 2020

Trans-ethnic meta-analysis of white blood cell phenotypes

scientific article

Transcriptional profile of platelets and iPSC-derived megakaryocytes from whole genome and RNA sequencing

scientific article published on 22 October 2020

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

scientific article published on 23 December 2019

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

scientific article

WGSA: an annotation pipeline for human genome sequencing studies.

scientific article published on 22 September 2015

Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation

scientific article published on 16 March 2017

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

scientific article

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

article

Whole-genome sequence-based analysis of high-density lipoprotein cholesterol

scientific article (publication date: August 2013)

Whole-genome sequence-based analysis of thyroid function.

scientific article

Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program

scientific article published in 2021

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