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List of works by Galina Florova

Active α-macroglobulin is a reservoir for urokinase after fibrinolytic therapy in rabbits with tetracycline-induced pleural injury and in human pleural fluids

scientific article published on 30 August 2013

Alkyl-CoA disulfides as inhibitors and mechanistic probes for FabH enzymes

scientific article

Alteration of the fatty acid profile of Streptomyces coelicolor by replacement of the initiation enzyme 3-ketoacyl acyl carrier protein synthase III (FabH).

scientific article

An unexpected interaction between the modular polyketide synthases, erythromycin DEBS1 and pikromycin PikAIV, leads to efficient triketide lactone synthesis

scientific article published in September 2002

Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine

scholarly article

Crotonyl-coenzyme A reductase provides methylmalonyl-CoA precursors for monensin biosynthesis by Streptomyces cinnamonensis in an oil-based extended fermentation

scientific article

Dose dependency of outcomes of intrapleural fibrinolytic therapy in new rabbit empyema models.

scientific article published on 24 June 2016

Effects of Extracellular DNA on Plasminogen Activation and Fibrinolysis ⬇️

scientific article published on October 5, 2011

Elucidation of final steps of the marineosins biosynthetic pathway through identification and characterization of the corresponding gene cluster ⬇️

scientific article published on 12 March 2014

Enzymes involved in fatty acid and polyketide biosynthesis in Streptomyces glaucescens: role of FabH and FabD and their acyl carrier protein specificity

scientific article

Fibrin Turnover and Organization of Pleural Injury: Bench to Bedside.

scientific article published on 18 January 2018

Formulation for a novel inhaled peptide therapeutic for idiopathic pulmonary fibrosis.

scientific article published on 23 August 2017

High titer production of tetracenomycins by heterologous expression of the pathway in a Streptomyces cinnamonensis industrial monensin producer strain.

scientific article published on 10 July 2009

Increased expression of plasminogen activator inhibitor-1 (PAI-1) is associated with depression and depressive phenotype in C57Bl/6J mice

scientific article published on 16 November 2019

Intrapleural adenoviral delivery of human plasminogen activator inhibitor-1 exacerbates tetracycline-induced pleural injury in rabbits ⬇️

scientific article published on September 20, 2012

Lack of durable protection against cotton smoke-induced acute lung injury in sheep by nebulized single chain urokinase plasminogen activator or tissue plasminogen activator.

scientific article

Lipoprotein receptor-related protein 1 regulates collagen 1 expression, proteolysis, and migration in human pleural mesothelial cells

scientific article published on February 2012

Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction

scientific article published on 20 February 2020

Multiple pathways for acetate assimilation in Streptomyces cinnamonensis ⬇️

scientific article

Nebulization of Single-Chain Tissue-Type and Single-Chain Urokinase Plasminogen Activator for Treatment of Inhalational Smoke-Induced Acute Lung Injury

scientific article published on 30 April 2018

Novel aspects of urokinase function in the injured lung: role of α2-macroglobulin

scientific article

Organizing empyema induced in mice by Streptococcus pneumoniae: effects of plasminogen activator inhibitor-1 deficiency

scientific article published on 13 May 2016

Perfluorochemical-facilitated plasminogen activator delivery to the airways: A novel treatment for inhalational smoke-induced acute lung injury

scientific article published on 01 January 2020

Phase 1 trial of intrapleural LTI-01; single chain urokinase in complicated parapneumonic effusions or empyema.

scientific article published on 18 April 2019

Plasminogen activator inhibitor-1 deficiency augments visceral mesothelial organization, intrapleural coagulation, and lung restriction in mice with carbon black/bleomycin-induced pleural injury

scientific article published on February 2014

Plasminogen activator inhibitor-1 suppresses profibrotic responses in fibroblasts from fibrotic lungs

scientific article

Post-transcriptional regulation of plasminogen activator inhibitor type-1 expression in human pleural mesothelial cells

scientific article published on 23 October 2009

Precision-guided, Personalized Intrapleural Fibrinolytic Therapy for Empyema and Complicated Parapneumonic Pleural Effusions: The Case for the Fibrinolytic Potential.

scientific article published in July 2017

Remarkable stabilization of plasminogen activator inhibitor 1 in a "molecular sandwich" complex.

scientific article published on 25 June 2013

Streptomyces coelicolor RedP and FabH enzymes, initiating undecylprodiginine and fatty acid biosynthesis, exhibit distinct acyl-CoA and malonyl-acyl carrier protein substrate specificities

scientific article published on 04 January 2012

Structural and Stereochemical Analysis of a Modular Polyketide Synthase Ketoreductase Domain Required for the Generation of a cis-Alkene

scientific article

Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces coelicolor

scientific article

Synthesis and biological evaluation of thiazolidine-2-one 1,1-dioxide as inhibitors of Escherichia coli beta-ketoacyl-ACP-synthase III (FabH).

scientific article published on December 2006

Targeting of plasminogen activator inhibitor 1 improves fibrinolytic therapy for tetracycline-induced pleural injury in rabbits.

scientific article published in April 2015

Targeting plasminogen activator inhibitor-1 in tetracycline-induced pleural injury in rabbits.

scientific article published on 31 August 2017

The time course of resolution of adhesions during fibrinolytic therapy in tetracycline-induced pleural injury in rabbits.

scientific article

Wood Bark Smoke Induces Lung and Pleural Plasminogen Activator Inhibitor 1 and Stabilizes Its mRNA in Porcine Lung Cells ⬇️

scientific article published on August 1, 2011

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