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List of works by Jürgen Venitz

2-Methoxyestradiol, a promising anticancer agent

scientific journal article

A phase II clinical trial of sorafenib in androgen-independent prostate cancer

scientific article published in January 2008

A theoretical model for the effects of reduced hemoglobin-oxygen affinity on tumor oxygenation

scientific article published in May 2002

Antiangiogenesis therapeutic strategies in prostate cancer

scientific article

Characterization of in vitro and in vivo metabolic pathways of the investigational anticancer agent, 2-methoxyestradiol

scientific article published on 01 July 2007

Chemically modified tetracyclines as inhibitors of matrix metalloproteinases

scientific article published in June 2004

Clinical Pharmacokinetics and Drug‐Drug Interactions of Endothelin Receptor Antagonists in Pulmonary Arterial Hypertension ⬇️

scientific article published on December 28, 2011

Comparison of Neural Network and Multiple Linear Regression as Dissolution Predictors ⬇️

scientific article published on March 1, 2003

Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin

scientific article published on 19 October 2011

Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin. Corrigendum.

scientific article published on 5 November 2011

Cumulative organic anion transporter-mediated drug-drug interaction potential of multiple components in salvia miltiorrhiza (danshen) preparations

scientific article

Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease.

scientific article published on 31 August 2017

Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Prodrugs as Drug Candidates for the Treatment of Ischemic Disorders: Insights into NO-Releasing Prodrug Biotransformation and Hemoglobin-NO Biochemistry

scientific article

Determination of 2-methoxyestradiol in human plasma, using liquid chromatography/tandem mass spectrometry

scientific article

Determination of CC-5013, an analogue of thalidomide, in human plasma by liquid chromatography-mass spectrometry

scientific article published in November 2004

Determination of MS-275, a novel histone deacetylase inhibitor, in human plasma by liquid chromatography-electrospray mass spectrometry

scientific article published in May 2004

Determination of PF-04928473 in human plasma using liquid chromatography with tandem mass spectrometry.

scientific article

Determination of the antiangiogenesis agent 2-methoxyestradiol in human plasma by liquid chromatography with ultraviolet detection

scientific article

Development of a rapid and sensitive LC-MS/MS assay for the determination of sorafenib in human plasma

scientific article published on January 2008

Effect of uptake transporters OAT3 and OATP1B1 and efflux transporter MRP2 on the pharmacokinetics of eluxadoline

scientific article

Exploration of Structure-Activity Relationship of Aromatic Aldehydes Bearing Pyridinylmethoxy-Methyl Esters as Novel Antisickling Agents

scientific article published on 18 November 2020

Factors Involved in the Pharmacokinetics of COL‐3, a Matrix Metalloproteinase Inhibitor, in Patients with Refractory Metastatic Cancer: Clinical and Experimental Studies ⬇️

scientific article published on October 1, 2003

Factors affecting the pharmacokinetic profile of MS-275, a novel histone deacetylase inhibitor, in patients with cancer

scientific article published in September 2006

Final analysis of a phase II trial using sorafenib for metastatic castration-resistant prostate cancer.

scientific article

Fluoroquinolone disposition: identification of the contribution of renal secretory and reabsorptive drug transporters.

scientific article published on 22 March 2012

Human Organic Cation Transporters 1 ( SLC22A1 ), 2 ( SLC22A2 ), and 3 ( SLC22A3 ) as Disposition Pathways for Fluoroquinolone Antimicrobials ⬇️

scientific article published on April 1, 2013

Hypertension and hand-foot skin reactions related to VEGFR2 genotype and improved clinical outcome following bevacizumab and sorafenib

scientific article

In Vitro Tests for Aerosol Deposition. IV: Simulating Variations in Human Breath Profiles for Realistic DPI Testing

scientific article published on 08 October 2015

Interspecies differences in plasma protein binding of MS-275, a novel histone deacetylase inhibitor

scientific article published on 19 July 2005

Matrix metalloproteinase inhibitors: do they have a place in anticancer therapy?

scientific article

Non-clinical safety and pharmacokinetic evaluations of propylene glycol aerosol in Sprague-Dawley rats and Beagle dogs ⬇️

scientific article published on June 12, 2011

Pharmacogenetics of estrogen metabolism and transport in relation to cancer

scientific article published on December 2003

Pharmacokinetics and safety of ambrisentan in combination with sildenafil in healthy volunteers

scientific article published in October 2008

Phase 1 study evaluating the safety and pharmacokinetics of pralatrexate in relapsed/refractory advanced solid tumors and lymphoma patients with mild, moderate, and severe renal impairment

scientific article published on 16 September 2016

Phase I clinical trial of oral 2-methoxyestradiol, an antiangiogenic and apoptotic agent, in patients with solid tumors

scientific article published on 22 January 2006

Plasma protein binding of the investigational anticancer agent 2-methoxyestradiol

scientific article published on 01 September 2006

Population pharmacokinetic analysis of sorafenib in patients with solid tumours.

scientific article

Preclinical Disposition (In Vitro) of Novel μ-Opioid Receptor Selective Antagonists ⬇️

scientific article published on June 17, 2011

Randomized discontinuation trial of sorafenib (BAY 43-9006).

scientific article

Rational design of pyridyl derivatives of vanillin for the treatment of sickle cell disease.

scientific article published on 6 April 2018

Rational development of histone deacetylase inhibitors as anticancer agents: a review

scientific article

Rational modification of vanillin derivatives to stereospecifically destabilize sickle hemoglobin polymer formation

scientific article published on 02 October 2018

Solute disposition in the rat lung in vivo and in vitro: determining regional absorption kinetics in the presence of mucociliary escalator

scientific article published on February 2002

The pharmacokinetics and pharmacodynamics of warfarin in combination with ambrisentan in healthy volunteers

scientific article published on 04 February 2009

The pharmacokinetics of enoxaparin do not correlate with its pharmacodynamic effect in patients receiving dialysis therapies.

scientific article

The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors

scientific article published on 15 September 2009

Two steps forward, one step back: mycophenolate mofetil treatment for myasthenia gravis in the United States

scientific article published on 31 March 2015

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