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List of works by Ann Marie Zavacki

A Global Loss of Dio2 Leads to Unexpected Changes in Function and Fiber Types of Slow Skeletal Muscle in Male Mice

scientific article published on 01 May 2019

A Novel Retinoid X Receptor-Independent Thyroid Hormone Response Element Is Present in the Human Type 1 Deiodinase Gene ⬇️

scientific article published on September 1, 1995

A Type 2 Deiodinase-Dependent Increase in Vegfa Mediates Myoblast-Endothelial Cell Crosstalk During Skeletal Muscle Regeneration

scientific article published on 12 August 2020

A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons

scientific article

Antioxidant function of a novel selenoprotein in Drosophila melanogaster

scientific article published on December 2003

CARs and drugs: a risky combination

scientific article published in March 2005

Catalysis leads to posttranslational inactivation of the type 1 deiodinase and alters its conformation ⬇️

scientific article published on April 27, 2012

Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling

scientific article

Coupled tRNA(Sec)-dependent assembly of the selenocysteine decoding apparatus

scientific article published in March 2003

Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice

scientific article (publication date: October 2004)

Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation

scientific article

Differential Growth Rates of Benign vs. Malignant Thyroid Nodules

scientific article published on 12 October 2017

Differential effects of refeeding on melanocortin-responsive neurons in the hypothalamic paraventricular nucleus

scientific article published on 8 May 2008

Dominant negative inhibition by mutant thyroid hormone receptors is thyroid hormone response element and receptor isoform specific

scientific article published on October 1993

Endoplasmic reticulum-associated degradation of the human type 2 iodothyronine deiodinase (D2) is mediated via an association between mammalian UBC7 and the carboxyl region of D2.

scientific article

Enhancement of thyroid hormone receptor isoform specificity by insertion of a distant half-site into a thyroid hormone response element

scientific article published on 01 April 1996

Establishment of a novel porcine model to study the impact of active stretching on a local Carrageenan-induced inflammation

scientific article published on 14 May 2020

FOR, a novel orphan nuclear receptor related to farnesoid X receptor

scientific article published on 26 February 2002

In vivo dimerization of types 1, 2, and 3 iodothyronine selenodeiodinases

scientific article

Knockdown of the type 3 iodothyronine deiodinase (D3) interacting protein peroxiredoxin 3 decreases D3-mediated deiodination in intact cells.

scientific article published on 09 October 2009

LXRs regulate the balance between fat storage and oxidation.

scientific article published in April 2005

Mice with a Targeted Deletion of the Type 2 Deiodinase Are Insulin Resistant and Susceptible to Diet Induced Obesity ⬇️

scientific article published on June 16, 2011

Mice with impaired extrathyroidal thyroxine to 3,5,3'-triiodothyronine conversion maintain normal serum 3,5,3'-triiodothyronine concentrations

scientific article published on 30 November 2006

Myocardial Induction of Type 3 Deiodinase in Dilated Cardiomyopathy

scientific article published on 17 March 2017

Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells.

scientific article

Physiological role and regulation of iodothyronine deiodinases: A 2011 update ⬇️

scientific article published on March 21, 2011

Quantitative Analysis of the Benefits and Risk of Thyroid Nodule Evaluation in Patients ≥70 Years Old.

scientific article published on 2 April 2018

RTHα, a Newly Recognized Phenotype of the Resistance to Thyroid Hormone (RTH) Syndrome in Patients With THRA Gene Mutations ⬇️

scientific article published on July 1, 2013

Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway.

scientific article

Regulation of thyroid hormones and branchial iodothyronine deiodinases during freshwater acclimation in tilapia

Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism.

scientific article

Retinoid-X receptor (RXR) differentially augments thyroid hormone response in cell lines as a function of the response element and endogenous RXR content

scientific article published on February 1995

Role of the Iodothyronine Deiodinases in the Physiology and Pathophysiology of Thyroid Hormone Action ⬇️

scientific article published on January 1, 2012

SAT-564 The Role Of Se Recycling In Regulating Iodothyronine-deiodinases In The Skeletal Muscle.

scientific article published on 30 April 2019

SAT-LB094 The Role of Thyroid Hormone in the Beneficial Effects of Stretching.

scientific article published on 30 April 2019

SAT-LB095 The Role of Type 2 Deiodinase in Interactions Between Muscle Stem Cells and Endothelial Cells.

scientific article

Shp deletion prevents hepatic steatosis and when combined with Fxr loss protects against type 2 diabetes

scientific article published on 06 June 2017

Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes.

scholarly article

Soy protein diet alters expression of hepatic genes regulating fatty acid and thyroid hormone metabolism in the male rat.

scientific article published on 3 December 2009

Structural features of thyroid hormone response elements that increase susceptibility to inhibition by an RTH mutant thyroid hormone receptor

scientific article published on July 1996

T3 Induces Both Markers of Maturation and Aging in Pancreatic β-Cells.

scientific article published on 6 April 2018

The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase

scientific article

The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate

scientific article

The arrestin domain-containing 3 protein regulates body mass and energy expenditure

scientific article

The selective loss of the type 2 iodothyronine deiodinase in mouse thyrotrophs increases basal TSH but blunts the thyrotropin response to hypothyroidism

scientific article

The thyroid hormone activating enzyme, type 2 deiodinase, induces myogenic differentiation by regulating mitochondrial metabolism and reducing oxidative stress.

scientific article published on 22 May 2019

Thyroid Hormone Promotes Postnatal Rat Pancreatic β-Cell Development and Glucose-Responsive Insulin Secretion Through MAFA ⬇️

scientific article published on January 10, 2013

Thyroid hormone receptor binds with unique properties to response elements that contain hexamer domains in an inverted palindrome arrangement

scientific article published in April 1994

Thyroid hormones and skeletal muscle--new insights and potential implications

scientific article

Thyroxine-induced expression of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase ⬇️

scientific article published on July 25, 2011

Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse.

scientific article published on 9 December 2004

Type 2 iodothyronine deiodinase levels are higher in slow-twitch than fast-twitch mouse skeletal muscle and are increased in hypothyroidism.

scientific article

Type II iodothyronine deiodinase provides intracellular 3,5,3′-triiodothyronine to normal and regenerating mouse skeletal muscle ⬇️

scientific article published on July 19, 2011

Type-2 iodothyronine 5'deiodinase (D2) in skeletal muscle of C57Bl/6 mice. II. Evidence for a role of D2 in the hypermetabolism of thyroid hormone receptor alpha-deficient mice

scientific article

Ubiquitination-induced conformational change within the deiodinase dimer is a switch regulating enzyme activity.

scientific article published on 23 April 2007

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