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List of works by Philine Wangemann

A claudin-9-based ion permeability barrier is essential for hearing.

scientific article

Adrenergic and muscarinic control of cochlear endolymph production

scientific article

Apical membrane P2Y4 purinergic receptor controls K+ secretion by strial marginal cell epithelium

scientific article

Calcium sparks in the intact gerbil spiral modiolar artery.

scientific article

Chemical synthesis of tetracyclic terpenes and evaluation of antagonistic activity on endothelin-A receptors and voltage-gated calcium channels

scientific article

Developmental delays consistent with cochlear hypothyroidism contribute to failure to develop hearing in mice lacking Slc26a4/pendrin expression

scientific article published on 19 August 2009

Developmental expression of solute carrier family 26A member 4 (SLC26A4/pendrin) during amelogenesis in developing rodent teeth

scientific article

ETA receptors in the gerbil spiral modiolar artery

scientific article

Endolymphatic Na+ and K+ Concentrations during Cochlear Growth and Enlargement in Mice Lacking Slc26a4/pendrin ⬇️

scientific article published on May 31, 2013

Epithelial Cell Stretching and Luminal Acidification Lead to a Retarded Development of Stria Vascularis and Deafness in Mice Lacking Pendrin ⬇️

scientific article published on March 14, 2011

Expression of epithelial calcium transport system in rat cochlea and vestibular labyrinth.

scientific article

Failure of Fluid Absorption in the Endolymphatic Sac Initiates Cochlear Enlargement that Leads to Deafness in Mice Lacking Pendrin Expression ⬇️

scientific article published on November 17, 2010

Free radical stress-mediated loss of Kcnj10 protein expression in stria vascularis contributes to deafness in Pendred syndrome mouse model

scientific article

Functional significance of channels and transporters expressed in the inner ear and kidney

scientific article published on August 2007

Gender differences in myogenic regulation along the vascular tree of the gerbil cochlea

scientific article published on 29 September 2011

Hearing loss associated with enlargement of the vestibular aqueduct: Mechanistic insights from clinical phenotypes, genotypes, and mouse models ⬇️

scientific article published on June 6, 2011

I(sK) Channel in Strial Marginal Cells. Voltage-Dependence, Ion-Selectivity, Inhibition by 293B and Sensitivity to Clofilium.

scientific article

ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells

scientific article

K(+) cycling and its regulation in the cochlea and the vestibular labyrinth

scientific article

K+ cycling and the endocochlear potential

scientific article (publication date: March 2002)

Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels

scientific article published on 2 January 2007

Loss of KCNJ10 protein expression abolishes endocochlear potential and causes deafness in Pendred syndrome mouse model

scientific article

Loss of cochlear HCO3- secretion causes deafness via endolymphatic acidification and inhibition of Ca2+ reabsorption in a Pendred syndrome mouse model

scientific article

Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model

scientific article

Microarray-based comparison of three amplification methods for nanogram amounts of total RNA.

scientific article

Molecular and pharmacological characteristics of the gerbil α1a-adrenergic receptor ⬇️

scientific article published on November 10, 2011

Mouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisition

scientific article

Mouse models for pendrin-associated loss of cochlear and vestibular function

scientific article published on 18 December 2013

Mutations of KCNJ10 together with mutations of SLC26A4 cause digenic nonsyndromic hearing loss associated with enlarged vestibular aqueduct syndrome

scientific article published on 07 May 2009

N-Ethylmaleimide Stimulates and Inhibits Ion Transport in Vestibular Dark Cells of Gerbil ⬇️

scientific article published on January 1, 1994

NOS inhibition enhances myogenic tone by increasing rho-kinase mediated Ca2+ sensitivity in the male but not the female gerbil spiral modiolar artery

scientific article

Non-linear classification for on-the-fly fractional mass filtering and targeted precursor fragmentation in mass spectrometry experiments ⬇️

scientific article published on 4 February 2010

Pharmacological reversal of endothelin-1 mediated constriction of the spiral modiolar artery: a potential new treatment for sudden sensorineural hearing loss

scientific article

Potassium ion movement in the inner ear: insights from genetic disease and mouse models

scientific article

Ryanodine-induced vasoconstriction of the gerbil spiral modiolar artery depends on the Ca2+ sensitivity but not on Ca2+ sparks or BK channels

scientific article

SLC26A4 Targeted to the Endolymphatic Sac Rescues Hearing and Balance in Slc26a4 Mutant Mice ⬇️

scientific article published on July 11, 2013

SLC26A4 genotypes and phenotypes associated with enlargement of the vestibular aqueduct

scientific article

SLC26A4 mutation testing for hearing loss associated with enlargement of the vestibular aqueduct

scientific article published on May 2013

Slc26a4-insufficiency causes fluctuating hearing loss and stria vascularis dysfunction

scientific article

Slc26a7 chloride channel activity and localization in mouse Reissner's membrane epithelium

scientific article

Supporting sensory transduction: cochlear fluid homeostasis and the endocochlear potential

scientific article published on 20 July 2006

Targeted ablation of connexin26 in the inner ear epithelial gap junction network causes hearing impairment and cell death

scientific article

The Role of Pendrin in the Development of the Murine Inner Ear ⬇️

scientific article published on November 18, 2011

The gastric H,K-ATPase in stria vascularis contributes to pH regulation of cochlear endolymph but not to K secretion

scientific article

Tumor Necrosis Factor-α Enhances Microvascular Tone and Reduces Blood Flow in the Cochlea via Enhanced Sphingosine-1-Phosphate Signaling ⬇️

scientific article published on October 7, 2010

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