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List of works by Melissa J. Alldred

Apolipoprotein E4 genotype compromises brain exosome production

Attentional function and basal forebrain cholinergic neuron morphology during aging in the Ts65Dn mouse model of Down syndrome

scientific article published on 30 December 2015

Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy.

scientific article

Brain-derived neurotrophic factor (BDNF) and TrkB hippocampal gene expression are putative predictors of neuritic plaque and neurofibrillary tangle pathology

scientific article published on 23 July 2019

CA1 pyramidal neuron gene expression mosaics in the Ts65Dn murine model of Down syndrome and Alzheimer's disease following maternal choline supplementation (MCS).

scientific article published on 2 February 2018

Calorie Restriction Suppresses Age-Dependent Hippocampal Transcriptional Signatures

scientific article published on 29 July 2015

Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway

scientific article

Distinct gamma2 subunit domains mediate clustering and synaptic function of postsynaptic GABAA receptors and gephyrin.

scientific article published on January 2005

Effects of Maternal Choline Supplementation on the Septohippocampal Cholinergic System in the Ts65Dn Mouse Model of Down Syndrome

scientific article published on 20 September 2015

Enhanced exosome secretion in Down syndrome brain - a protective mechanism to alleviate neuronal endosomal abnormalities

scientific article published on 29 August 2017

Expression and proteolytic processing of the amyloid precursor protein is unaffected by the expression of the three human apolipoprotein E alleles in the brains of mice

scientific article published in 2022

Expression profile analysis of hippocampal CA1 pyramidal neurons in aged Ts65Dn mice, a model of Down syndrome (DS) and Alzheimer's disease (AD).

scientific article

Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice

scientific article

Expression profiling suggests microglial impairment in HIV neuropathogenesis.

scientific article published on 25 January 2018

Frontal cortex and striatal cellular and molecular pathobiology in individuals with Down syndrome with and without dementia

scientific article published on 07 February 2019

Gene expression levels assessed by CA1 pyramidal neuron and regional hippocampal dissections in Alzheimer's disease

scientific article

Glutamatergic transmission aberration: a major cause of behavioral deficits in a murine model of Down's syndrome.

scientific article published on April 2014

Long-term effects of maternal choline supplementation on CA1 pyramidal neuron gene expression in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease

scientific article published on 10 June 2019

Maternal Choline Supplementation Alters Basal Forebrain Cholinergic Neuron Gene Expression in the Ts65Dn Mouse Model of Down Syndrome

scientific article published on 09 June 2019

Maternal Choline Supplementation: A Potential Prenatal Treatment for Down Syndrome and Alzheimer's Disease.

scientific article published on 20 September 2015

Maternal choline supplementation in a mouse model of Down syndrome: Effects on attention and nucleus basalis/substantia innominata neuron morphology in adult offspring

scientific article published on 10 November 2016

Maternal choline supplementation programs greater activity of the phosphatidylethanolamine N-methyltransferase (PEMT) pathway in adult Ts65Dn trisomic mice

scientific article

Mechanisms underlying insulin deficiency-induced acceleration of β-amyloidosis in a mouse model of Alzheimer's disease

scientific article (publication date: 2012)

Microarray analysis of CA1 pyramidal neurons in a mouse model of tauopathy reveals progressive synaptic dysfunction.

scientific article

Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression

scientific article

Reduction of β-amyloid and γ-secretase by calorie restriction in female Tg2576 mice

scientific article

Regional selectivity of rab5 and rab7 protein upregulation in mild cognitive impairment and Alzheimer's disease

scientific article

Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimer's disease

scientific article

Sex- and brain region-specific acceleration of β-amyloidogenesis following behavioral stress in a mouse model of Alzheimer's disease.

scientific article

Synaptic gene dysregulation within hippocampal CA1 pyramidal neurons in mild cognitive impairment.

scientific article published on 25 October 2013

Terminal Continuation (TC) RNA amplification enables expression profiling using minute RNA input obtained from mouse brain

scientific article published on 31 October 2008

Terminal continuation (TC) RNA amplification without second strand synthesis

scientific article

The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering

scientific article

The gamma2 subunit of GABA(A) receptors is a substrate for palmitoylation by GODZ

scientific article published on June 2004

Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.

scientific article

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