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List of works by Thomas Lengauer

A DNA methylation fingerprint of 1628 human samples

scientific article

A Fully Computational Model for Predicting Percutaneous Drug Absorption

article

A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains

scientific article published on 28 September 2018

A fast algorithm for finding dominators in a flowgraph

A fast flexible docking method using an incremental construction algorithm.

scientific article published in August 1996

A general concept for consistent documentation of computational analyses.

scientific article published on 8 June 2015

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

scientific article (publication date: February 2007)

A genotypic method for determining HIV-2 coreceptor usage enables epidemiological studies and clinical decision support

scientific article published on 20 December 2016

A hypergraph-based method for unification of existing protein structure- and sequence-families.

scientific article

A method for finding consensus breakpoints in the cancer genome from copy number data

scientific article

A new CARD15 mutation in Blau syndrome

scientific article published in June 2005

A new measure for functional similarity of gene products based on Gene Ontology

scientific article published on 15 June 2006

A simple iterative approach to parameter optimization.

scientific article published in January 2000

APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1.

scientific article published on 15 May 2011

Advantages of predicted phenotypes and statistical learning models in inferring virological response to antiretroviral therapy from HIV genotype

scientific article published in January 2009

Alignment of non-covalent interactions at protein-protein interfaces.

scientific article

AltAnalyze and DomainGraph: analyzing and visualizing exon expression data

scientific article

Ambulatory care for HIV-infected patients: differences in outcomes between hospital-based units and private practices: analysis of the RESINA cohort

scientific article

Amino acid variations in hepatitis C virus p7 and sensitivity to antiviral combination therapy with amantadine in chronic hepatitis C.

scientific article published in January 2006

An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data

scientific article

An integrative approach for predicting interactions of protein regions

scientific article

An integrative approach to gain insights into the cellular function of human ataxin-2

scientific article

Analysis of gene expression data with pathway scores.

scientific article

Analysis of physicochemical and structural properties determining HIV-1 coreceptor usage

scientific article

Analyzing epigenome data in context of genome evolution and human diseases

scientific article

Application of oncogenetic trees mixtures as a biostatistical model of the clonal cytogenetic evolution of meningiomas.

scientific article

Arby: automatic protein structure prediction using profile-profile alignment and confidence measures.

scientific article

Association between HIV-1 coreceptor usage and resistance to broadly neutralizing antibodies

scientific article published on October 2014

Association of HCV-related mixed cryoglobulinemia with specific mutational pattern of the HCV E2 protein and CD81 expression on peripheral B lymphocytes

scientific article published on August 2004

Asymptotically Tight Bounds on Time-Space Trade-offs in a Pebble Game

scientific article published in 1982

Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways

scientific article

Automated clustering of ensembles of alternative models in protein structure databases.

scientific article

Automatic generation of complementary descriptors with molecular graph networks

scientific article published on 01 September 2005

BLUEPRINT to decode the epigenetic signature written in blood.

scientific article

BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing

scientific article published on 11 May 2011

BiQ Analyzer HiMod: an interactive software tool for high-throughput locus-specific analysis of 5-methylcytosine and its oxidized derivatives

scientific article

BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing.

scientific article

Big Data in Natural Sciences, Humanities and Social Sciences——Review of the 6th Exploratory Round Table Conference

article published in 2016

Bioinformatical Assistance of Selecting Anti-HIV Therapies: Where Do We Stand? ⬇️

scientific article published on January 24, 2012

Bioinformatics prediction of HIV coreceptor usage

scientific article published on 01 December 2007

Bioinformatics-assisted anti-HIV therapy

scientific article published on 01 October 2006

Black-white pebbles and graph separation

Calculating the statistical significance of changes in pathway activity from gene expression data

scientific article published on 22 June 2004

Centralization: a new method for the normalization of gene expression data.

scientific article

Characterization and structural analysis of novel mutations in human immunodeficiency virus type 1 reverse transcriptase involved in the regulation of resistance to nonnucleoside inhibitors

scientific article

Classification with correlated features: unreliability of feature ranking and solutions

scientific article

Clinical relevance of the 2'-5'-oligoadenylate synthetase/RNase L system for treatment response in chronic hepatitis C.

scientific article published on 11 November 2008

Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection

scientific article published on 14 October 2005

Clinical use, efficacy, and durability of maraviroc for antiretroviral therapy in routine care: A European survey

scientific article published on 21 November 2019

Co-clustering of biological networks and gene expression data

scientific article

Combined similarity and QSPR virtual screening for guest molecules of β-cyclodextrin

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction

scientific article

Comparative analysis of neutrophil and monocyte epigenomes

Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues.

scientific article

Comparison of classifier fusion methods for predicting response to anti HIV-1 therapy

scientific article

Comprehensive analysis of DNA methylation data with RnBeads

scientific article

Computational analysis of human protein interaction networks.

scientific article published on August 2007

Computational epigenetics

scientific article

Computational methods for biomolecular docking.

scientific article

Computational methods for the design of effective therapies against drug resistant HIV strains

scientific article

Computational recognition of potassium channel sequences

scientific article published on 4 April 2006

Computing topological parameters of biological networks

scientific article published on 15 November 2007

Confidence measures for protein fold recognition

scientific article

Confirmation of human protein interaction data by human expression data

scientific article

Conformational analysis of alternative protein structures

scientific article published on 12 October 2007

Correction to On the Applicability of Elastic Network Normal Modes in Small-Molecule Docking

scholarly article published in Journal of Chemical Information and Modeling

Correction: DNA Methylation Patterns Facilitate the Identification of MicroRNA Transcription Start Sites: A Brain-Specific Study.

scientific article published on 30 December 2013

Correlation of amino acid variations within nonstructural 4B protein with initial viral kinetics during interferon-alpha-based therapy in HCV-1b-infected patients

scientific article published on 01 May 2007

Corrigendum to: Family-joining: A fast distance-based method for constructing generally labeled trees

scientific article published on 03 February 2020

CpG island mapping by epigenome prediction

scientific article

CpG island mapping by epigenome prediction

scientific article published on 03 May 2007

CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure

scientific article

DASMI: exchanging, annotating and assessing molecular interaction data

scientific article (publication date: 15 May 2009)

DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation

scientific article

DNA methylation patterns facilitate the identification of microRNA transcription start sites: a brain-specific study

scientific article

Dealing with sparse data in predicting outcomes of HIV combination therapies.

scientific article

Decomposing protein networks into domain-domain interactions.

scientific article published in September 2005

Deep sequencing reveals mutagenic effects of ribavirin during monotherapy of hepatitis C virus genotype 1-infected patients

scientific article published on 27 March 2013

DeepBlue epigenomic data server: programmatic data retrieval and analysis of epigenome region sets

scientific article

DeepBlueR: large-scale epigenomic analysis in R.

scientific article published on 22 February 2017

Detection of distant structural similarities in a set of proteins using a fast graph-based method.

scientific article

Determination of Phenotypic Resistance Cutoffs From Routine Clinical Data

scientific article

Dimerization of the hepatitis C virus nonstructural protein 4B depends on the integrity of an aminoterminal basic leucine zipper

scientific article published on July 2010

Disease-associated variants in PYPAF1 and NOD2 result in similar alterations of conserved sequence

scientific article published on 01 November 2003

Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays

scientific article

Diversity and complexity of HIV-1 drug resistance: a bioinformatics approach to predicting phenotype from genotype

scientific article

Diversity and functional plasticity of eukaryotic selenoproteins: identification and characterization of the SelJ family

scientific article

Docking and scoring with alternative side-chain conformations

scientific article

DynaPred: a structure and sequence based method for the prediction of MHC class I binding peptide sequences and conformations

scientific article published in July 2006

Dynamics of NRTI Resistance Mutations during Therapy Interruption

article

Effect of ribavirin on the frequency of RNase L cleavage sites within the hepatitis C viral genome.

scientific article published on 15 September 2009

Effects of sequence alterations on results from genotypic tropism testing

scientific article

Efficient computation of root mean square deviations under rigid transformations

scientific article published on 19 December 2013

Elucidating the energetic contributions to the binding free energy.

scientific article published in January 2017

Endogenous or exogenous spreading of HIV-1 in Nordrhein-Westfalen, Germany, investigated by phylodynamic analysis of the RESINA Study cohort

scientific article published on 20 January 2012

Ensemble methods for classification in cheminformatics

scientific article published on 01 November 2004

Enthalpy-Entropy Compensation upon Molecular Conformational Changes

scientific article published on 11 March 2015

Entropy gain due to water release upon ligand binding.

scientific article published on 11 March 2014

EpiExplorer: live exploration and global analysis of large epigenomic datasets

scientific article published on 3 October 2012

EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data

scientific article

Epidemiology of transmitted drug resistance in chronically HIV-infected patients in Germany: the RESINA study 2001-2009

scientific article published on 24 January 2012

Epigenetic dynamics of monocyte-to-macrophage differentiation

scientific article published on 29 July 2016

Epigenom-Karten erstellen und nutzen

Epigenomic Profiling of Human CD4(+) T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development

scientific article published on November 2016

Erratum to: Making sense of big data in health research: towards an EU action plan

scientific article

Estimating HIV evolutionary pathways and the genetic barrier to drug resistance

scientific article published on 28 April 2005

Estimating cancer survival and clinical outcome based on genetic tumor progression scores

scientific article published on 10 February 2005

Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development.

scientific article published on 13 April 2018

Expression pattern analysis of transcribed HERV sequences is complicated by ex vivo recombination.

scientific article published on 6 June 2007

FLEXS: a method for fast flexible ligand superposition.

scientific article published in November 1998

Factor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer

scientific article published on 05 February 2007

Failure of Dolutegravir First-Line ART with Selection of Virus Carrying R263K and G118R

scientific article published on 01 August 2019

Family-Joining: A Fast Distance-Based Method for Constructing Generally Labeled Trees ⬇️

scientific article

Fifteen years of env C2V3C3 evolution in six individuals infected clonally with human immunodeficiency virus type 1.

scientific article published on November 2007

Flexible docking of ligands into synthetic receptors using a two-sided incremental construction algorithm

scientific article published in July 2006

From hype to reality: data science enabling personalized medicine

scientific article published on 27 August 2018

Full genome ultra-deep pyrosequencing associates G-to-A hypermutation of the hepatitis B virus genome with the natural progression of hepatitis B.

scientific article published on 7 June 2013

Fully automated flexible docking of ligands into flexible synthetic receptors using forward and inverse docking strategies

scientific article published in March 2006

Functional association of the polyglutamine proteins ataxin-2 and huntingtin

Functional evaluation of domain-domain interactions and human protein interaction networks

scientific article published on April 2007

GOTax: investigating biological processes and biochemical activities along the taxonomic tree.

scientific article published on January 2007

Genetic variation in DLG5 is associated with inflammatory bowel disease

scientific article

Geno2pheno: Estimating phenotypic drug resistance from HIV-1 genotypes

scientific article

Geno2pheno[454]: a Web server for the prediction of HIV-1 coreceptor usage from next-generation sequencing data

scientific article

Geno2pheno[HCV] - A Web-based Interpretation System to Support Hepatitis C Treatment Decisions in the Era of Direct-Acting Antiviral Agents

scientific article

Genomic distribution and inter-sample variation of non-CpG methylation across human cell types

scientific article

Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis ⬇️

scientific article

Genotyping hepatitis B virus dual infections using population-based sequence data

scientific article

HIV prevalence and route of transmission in Turkish immigrants living in North-Rhine Westphalia, Germany

scientific article published on 02 April 2011

HIV-1 mutational pathways under multidrug therapy

scientific article published on 27 July 2011

HLA class I allele associations with HCV genetic variants in patients with chronic HCV genotypes 1a or 1b infection

scientific article

Hierarchical Bayes Model for Predicting Effectiveness of HIV Combination Therapies ⬇️

scientific article published on January 1, 2012

How Molecular Conformational Changes Affect Changes in Free Energy

scientific article published in July 2015

How to write a presubmission inquiry

scientific article published on 26 February 2015

IRECS: a new algorithm for the selection of most probable ensembles of side-chain conformations in protein models

scientific article

ISCB Ebola Award for Important Future Research on the Computational Biology of Ebola Virus

scientific article (publication date: 29 January 2015)

ISCB Ebola Award for Important Future Research on the Computational Biology of Ebola Virus

scientific article

ISCB's Initial Reaction to The New England Journal of Medicine Editorial on Data Sharing

scientific article

ISCB's initial reaction to New England Journal of Medicine editorial on data sharing

scientific article

ISMB/ECCB 2007: The Premier Conference on Computational Biology.

scientific article published on 25 May 2007

Identification of PatL1, a human homolog to yeast P body component Pat1

scientific article published on 06 September 2007

Identification of mammalian orthologs associates PYPAF5 with distinct functional roles

scientific article

Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

scientific article published in 2021

Importance of bioinformatics in personalised medicine

scientific article published in November 2013

Improved cyclodextrin-based receptors for camptothecin by inverse virtual screening

scientific article

Improved prediction of HIV‐1 coreceptor usage with sequence information from the second hypervariable loop of gp120

scientific article published on 01 November 2010

Improved prediction of response to antiretroviral combination therapy using the genetic barrier to drug resistance

scientific article published in January 2007

Improved scoring of functional groups from gene expression data by decorrelating GO graph structure

scientific article

Improved therapy-success prediction with GSS estimated from clinical HIV-1 sequences

scientific article

Improving HIV coreceptor usage prediction in the clinic using hints from next-generation sequencing data ⬇️

scientific article published on September 15, 2012

Improving disease gene prioritization using the semantic similarity of Gene Ontology terms

scientific article

Improving fold recognition of protein threading by experimental distance constraints.

scientific article

Improving the quality of protein structure models by selecting from alignment alternatives

scientific article

Inferring short-range linkage information from sequencing chromatograms

scientific article

Integrating expression data with domain interaction networks

scientific article

Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters

scientific article published on 10 November 2018

Integrative visual analysis of the effects of alternative splicing on protein domain interaction networks.

scientific article

Inter-individual variation of DNA methylation and its implications for large-scale epigenome mapping

scientific article

Involvement of novel human immunodeficiency virus type 1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors

scientific article

Large oligomeric complex structures can be computationally assembled by efficiently combining docked interfaces

scientific article published on 6 August 2015

Lead Identification by Virtual Screening

Learning from past treatments and their outcome improves prediction of in vivo response to anti-HIV therapy

scientific article published on 14 January 2011

Learning multiple evolutionary pathways from cross-sectional data

scientific article

Local function conservation in sequence and structure space

scientific article

Local protein structure prediction using discriminative models

scientific article

Making sense of big data in health research: Towards an EU action plan

scientific article

Managing drug resistance in cancer: lessons from HIV therapy ⬇️

scientific article published on June 7, 2012

Message from the ISCB: ISCB Ebola award for important future research on the computational biology of Ebola virus

scientific article published on 2 February 2015

Metabolic screening of Saccharomyces cerevisiae single knockout strains reveals unexpected mobilization of metabolic potential

scientific article published in 2006

MethMarker: user-friendly design and optimization of gene-specific DNA methylation assays

scientific article published on 5 October 2009

Methods for optimizing antiviral combination therapies

scientific article

MicroRNA transcription start site prediction with multi-objective feature selection

scientific article published on 06 January 2012

Microarrays: how many do you need?

scientific article

Model selection for mixtures of mutagenetic trees

scientific article published on 23 June 2006

Modelling binding between CCR5 and CXCR4 receptors and their ligands suggests the surface electrostatic potential of the co-receptor to be a key player in the HIV-1 tropism.

scientific article published on 11 November 2013

Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus

scientific article

Moment invariants as shape recognition technique for comparing protein binding sites.

scientific article

Mtreemix: a software package for learning and using mixture models of mutagenetic trees

scientific article published on 18 January 2005

Multiple automatic base selection: protein-ligand docking based on incremental construction without manual intervention.

scientific article published in July 1997

Multiple-ligand-based virtual screening: methods and applications of the MTree approach

scientific article published in October 2005

Mutations in gp41 are correlated with coreceptor tropism but do not improve prediction methods substantially

scientific article published in January 2011

Mutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair

scientific article published on 28 November 2006

Mutations in the NB-ARC domain of I-2 that impair ATP hydrolysis cause autoactivation.

scientific article published on 17 February 2006

NOXclass: prediction of protein-protein interaction types

scientific article

Near-Neighbor Interactions in the NS3-4A Protease of HCV Impact Replicative Fitness of Drug-Resistant Viral Variants

scientific article published on 30 April 2019

New Methods Section in PLOS Computational Biology.

scientific article published on 7 March 2013

Novel Sm-like proteins with long C-terminal tails and associated methyltransferases

scientific article

Novel technologies for virtual screening

scientific article published on January 2004

On the applicability of elastic network normal modes in small-molecule docking

scientific article

Only slight impact of predicted replicative capacity for therapy response prediction

scientific article

POEM: Parameter Optimization using Ensemble Methods: application to target specific scoring functions

scientific article published in September 2005

Parameters Influencing Baseline HIV-1 Genotypic Tropism Testing Related to Clinical Outcome in Patients on Maraviroc

scientific article

Patients with high-grade gliomas harboring deletions of chromosomes 9p and 10q benefit from temozolomide treatment

scientific article

Paving the future: finding suitable ISMB venues

scientific article

Peptidomimetic escape mechanisms arise via genetic diversity in the ligand-binding site of the hepatitis C virus NS3/4A serine protease

scientific article published on 7 December 2011

Permutation importance: a corrected feature importance measure

scholarly article

Personalized HIV therapy to control drug resistance

scientific article

Placement of medium-sized molecular fragments into active sites of proteins.

scientific article published in February 1996

Positive selection of HIV host factors and the evolution of lentivirus genes

scientific article

Predicting HIV coreceptor usage on the basis of genetic and clinical covariates.

scientific article published in January 2007

Predicting MHC class I epitopes in large datasets

scientific article

Predicting response to antiretroviral treatment by machine learning: the EuResist project

scientific article published on 24 January 2012

Predicting the response to combination antiretroviral therapy: retrospective validation of geno2pheno-THEO on a large clinical database

scientific article published in April 2009

Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach

scientific article published on December 2011

Prediction of response to antiretroviral therapy by human experts and by the EuResist data-driven expert system (the EVE study).

scientific article

Preserving charge and oxidation state of Au(III) ions in an agent-functionalized nanocrystal model system

scientific article

Prevalence and characteristics of hepatitis B and C virus infections in treatment-naïve HIV-infected patients

scientific article published on 19 September 2010

ProML--the protein markup language for specification of protein sequences, structures and families.

scientific article published on January 2002

Protein function from sequence and structure data.

scientific article

Protein structure prediction methods for drug design.

scientific article

Proviral DNA as a Target for HIV-1 Resistance Analysis

scientific article published on 27 June 2015

Pyranose oxidase identified as a member of the GMC oxidoreductase family.

scientific article

Quantitative comparison of within-sample heterogeneity scores for DNA methylation data

scientific article published on 27 February 2020

ROCR: visualizing classifier performance in R

scientific article (publication date: 15 October 2005)

Recco: recombination analysis using cost optimization

scientific article published on 17 February 2006

Reconstructing the ancestral germ line methylation state of young repeats

scientific article published on 06 January 2011

Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment

scientific article

Recursive dynamic programming for adaptive sequence and structure alignment.

scientific article published in January 1995

Reference-free deconvolution, visualization and interpretation of complex DNA methylation data using DecompPipeline, MeDeCom and FactorViz

scientific article published on 25 September 2020

Relative Principal Components Analysis: Application to Analyzing Biomolecular Conformational Changes

scientific article published on 6 March 2019

Results of the first international HIV-1 coreceptor proficiency panel test

scientific article published on 10 June 2017

RigFit: a new approach to superimposing ligand molecules.

scientific article published in September 1998

Risk factors associated with older age in treatment-naive HIV-positive patients

scientific article published on 24 January 2012

RnBeads 2.0: comprehensive analysis of DNA methylation data

article by Fabian Müller et al published 14 March 2019 in Genome Biology

Rtreemix: an R package for estimating evolutionary pathways and genetic progression scores

scientific article published on 20 August 2008

Sarcoidosis is associated with a truncating splice site mutation in BTNL2.

scientific article

Selecting anti-HIV therapies based on a variety of genomic and clinical factors

scientific article published on July 2008

Selective pressures of HLA genotypes and antiviral therapy on human immunodeficiency virus type 1 sequence mutation at a population level

scientific article

Sensitive detection of viral transcripts in human tumor transcriptomes

scientific article

Sequence and Structure Analysis of Distantly-Related Viruses Reveals Extensive Gene Transfer between Viruses and Hosts and among Viruses.

scientific article published on 19 October 2015

Short communication: selection of thymidine analogue resistance mutational patterns in children infected from a common HIV type 1 subtype G source

scientific article published in March 2010

Simple consensus procedures are effective and sufficient in secondary structure prediction.

scientific article

Software tool for automated processing of 13C labeling data from mass spectrometric spectra.

scientific article

Soluble immune markers in the different phases of chronic hepatitis B virus infection

scientific article published on 01 October 2019

Stability analysis of mixtures of mutagenetic trees

scientific article

Stable coreceptor usage of HIV in patients with ongoing treatment failure on HAART

scientific article published on 26 September 2006

Structural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage

scientific article published on 09 February 2007

Structural and functional analysis of a novel mutation of CYP21B in a heterozygote carrier of 21-hydroxylase deficiency

scientific article published on 19 July 2005

Structural and functional analysis of ataxin-2 and ataxin-3.

scientific article

Structural and functional comparison of the non-structural protein 4B in flaviviridae

scientific article published on 4 April 2007

Structural descriptors of gp120 V3 loop for the prediction of HIV-1 coreceptor usage

scientific article

Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2.

scientific article published on November 2003

Structural modeling of ataxin-3 reveals distant homology to adaptins

scientific article (publication date: February 2003)

Survey on the PABC recognition motif PAM2.

scientific article published in March 2004

Synthesis and Evaluation of (Pyridylmethylene)tetrahydronaphthalenes/-indanes and Structurally Modified Derivatives: Potent and Selective Inhibitors of Aldosterone Synthase

Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitors of aldosterone synthase.

scientific article published on March 2005

Synthesis and evaluation of imidazolylmethylenetetrahydronaphthalenes and imidazolylmethyleneindanes: potent inhibitors of aldosterone synthase

scientific article

Tenofovir resistance and resensitization

scientific article published on November 2003

The DFG Priority Program “Informatics Methods for the Analysis and Interpretation of Large Genomic Datasets” (DFG Schwerpunktprogramm “Informatikmethoden zur Analyse und Interpretation großer genomischer Datenmengen”)

scientific article published in 2005

The HIN domain of IFI-200 proteins consists of two OB folds

scientific article

The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources.

scientific article published in January 2004

The Role of Conformational Changes in Molecular Recognition

scientific article

The Seventh International Conference on Intelligent Systems for Molecular Biology (ISMB'99)

scientific article published in October 1999

The implications of alternative splicing in the ENCODE protein complement

scientific article (publication date: 27 March 2007)

The particle concept: placing discrete water molecules during protein-ligand docking predictions.

scientific article published in January 1999

Time-efficient docking of flexible ligands into active sites of proteins.

scientific article published in January 1995

Time-efficient flexible superposition of medium-sized molecules

scientific article published on July 1, 1997

Unique and assay specific features of NOMe-, ATAC- and DNase I-seq data

scientific article published on 01 November 2019

Using drug exposure for predicting drug resistance - A data-driven genotypic interpretation tool

scientific article (publication date: 2017)

V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV.

scientific article

Web-based analysis of (Epi-) genome data using EpiGRAPH and Galaxy

scientific article

[Resistance screening]

scientific article published on 01 April 2009

geno2pheno[ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data.

scientific article published in May 2018

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