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List of works by Ekkehard Dikomey

"Meeting Report DNA Repair 2006: Ninth Biennial Meeting of the German Society for Research on DNA Repair" [DNA Repair 6 (2007) 140-144].

scientific article

Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma

scientific article published on 28 November 2012

Blockage of epidermal growth factor receptor-phosphatidylinositol 3-kinase-AKT signaling increases radiosensitivity of K-RAS mutated human tumor cells in vitro by affecting DNA repair.

scientific article published on July 2006

Cellular and tumor radiosensitivity is correlated to epidermal growth factor receptor protein expression level in tumors without EGFR amplification

scientific article published on 20 April 2011

DNA Repair 2006: ninth biennial meeting of the German Society for Research on DNA repair.

scientific article published in January 2007

DNA damage by X-rays and their impact on replication processes.

scientific article published on 11 February 2012

EGF receptor inhibition radiosensitizes NSCLC cells by inducing senescence in cells sustaining DNA double-strand breaks

scientific article published on 18 August 2011

EGFR-targeted anti-cancer drugs in radiotherapy: preclinical evaluation of mechanisms

scientific article published on 14 May 2007

Effect of irradiation on the expression of DNA repair genes studied in human fibroblasts by real-time qPCR using three methods of reference gene validation.

scientific article

For X-irradiated normal human fibroblasts, only half of cell inactivation results from chromosomal damage

scientific article published on February 2004

HNSCC cell lines positive for HPV and p16 possess higher cellular radiosensitivity due to an impaired DSB repair capacity

scientific article published on 17 April 2013

HPV-positive HNSCC cell lines but not primary human fibroblasts are radiosensitized by the inhibition of Chk1.

scientific article published on 7 August 2013

Impact of homologous recombination on individual cellular radiosensitivity

scientific article published on 17 September 2008

In normal human fibroblasts variation in DSB repair capacity cannot be ascribed to radiation-induced changes in the localisation, expression or activity of major NHEJ proteins

scientific article published on 26 December 2007

In reply to Kapoor

scientific article published in July 2013

In tumor cells regulation of DNA double strand break repair through EGF receptor involves both NHEJ and HR and is independent of p53 and K-Ras status ⬇️

scientific article published on June 12, 2011

Inactivation of HNSCC cells by 90Y-labeled cetuximab strictly depends on the number of induced DNA double-strand breaks

scientific article published on 23 January 2013

Indicators of late normal tissue response after radiotherapy for head and neck cancer: fibroblasts, lymphocytes, genetics, DNA repair, and chromosome aberrations

Individual radiosensitivity measured with lymphocytes may be used to predict the risk of fibrosis after radiotherapy for breast cancer

scientific article published in November 2003

Induction and repair of radiation-induced DNA double-strand breaks in human fibroblasts are not affected by terminal differentiation

scientific article published in February 2004

Lymphoblastoid cell lines differing in p53 status show clear differences in basal gene expression with minor changes after irradiation

scientific article published on 14 August 2006

Mechanism of cell killing after ionizing radiation by a dominant negative DNA polymerase beta

scientific article

Molecular mechanisms of individual radiosensitivity studied in normal diploid human fibroblasts ⬇️

scientific article published on November 15, 2003

Molecular radiation biology/oncology

scientific article published on 01 September 2004

Molecular radiation biology/oncology at its best: cutting edge research presented at the 13th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology

scientific article published in September 2013

No Effect of the Transforming Growth Factor β1 Promoter Polymorphism C-509T on TGFB1 Gene Expression, Protein Secretion, or Cellular Radiosensitivity ⬇️

scientific article published on May 15, 2012

RAD51 overexpression is a negative prognostic marker for colorectal adenocarcinoma ⬇️

scientific article published on November 5, 2012

Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase ⬇️

scientific article published on June 22, 2012

Radiosensitization of HNSCC cells by EGFR inhibition depends on the induction of cell cycle arrests

scientific article

Radiosensitization of NSCLC cells by EGFR inhibition is the result of an enhanced p53-dependent G1 arrest

scientific article

Radiosensitization of tumour cell lines by the polyphenol Gossypol results from depressed double-strand break repair and not from enhanced apoptosis

scientific article published on 22 May 2007

Sex-specific aspects of tumor therapy

scientific article published on 26 February 2009

Sorafenib inhibits cell growth but fails to enhance radio- and chemosensitivity of glioblastoma cell lines

scientific article published on 17 August 2016

Sorafenib sensitizes head and neck squamous cell carcinoma cells to ionizing radiation

scientific article published on 13 August 2013

The epidermal growth factor receptor modulates DNA double-strand break repair by regulating non-homologous end-joining

scientific article published on 19 June 2010

The extreme radiosensitivity of the squamous cell carcinoma SKX is due to a defect in double-strand break repair

scientific article

The inhibition of PARP but not EGFR results in the radiosensitization of HPV/p16-positive HNSCC cell lines

scientific article published on 10 November 2014

Why recent studies relating normal tissue response to individual radiosensitivity might have failed and how new studies should be performed

scientific article

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