Search filters

List of works by Noel K. Maclaren

64,000 Mr autoantibodies as predictors of insulin-dependent diabetes

scientific article published on 01 June 1990

A prospective study of the development of diabetes in relatives of patients with insulin-dependent diabetes

scientific article published on 01 October 1990

Additive susceptibility to insulin-dependent diabetes conferred by HLA-DQB1 and insulin genes

scientific article published on 01 January 1994

Adrenal autoantibodies and Addison disease in insulin-dependent diabetes mellitus

scientific article published on 01 August 1980

Adrenal dysfunction in asymptomatic patients with adrenocortical autoantibodies

scientific article published on 01 June 1984

Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27

scientific article published on October 1995

Age and family relationship accentuate the risk of insulin-dependent diabetes mellitus (IDDM) in relatives of patients with IDDM

scientific article published on 01 December 1995

Although DR3-DQB1*0201 may be associated with multiple component diseases of the autoimmune polyglandular syndromes, the human leukocyte antigen DR4-DQB1*0302 haplotype is implicated only in beta-cell autoimmunity

scientific article published on July 1996

Androgen sensitization of streptozotocin-induced diabetes in mice

scientific article published on 01 September 1980

Antibodies to melanocytes in vitiligo

scientific article published on 01 January 1984

Antigen based therapies to prevent diabetes in NOD mice

scientific article published on 01 June 1996

Antigen-specific immunotherapy: oral tolerance and subcutaneous immunization in the treatment of insulin-dependent diabetes.

scientific article published on December 1993

Application of synthetic oligonucleotides to detect DQ beta genes transmission within insulin-dependent diabetes families

scientific article published on 01 October 1989

Are insulin autoantibodies markers for insulin-dependent diabetes mellitus?

scientific article published on August 1986

Association of LMP2 and LMP7 genes within the major histocompatibility complex with insulin-dependent diabetes mellitus: population and family studies.

scientific article published on February 1995

Association of class II human histocompatibility leukocyte antigens with rheumatic fever

scientific article published on June 1986

Association of diabetes mellitus and chronic hepatitis C virus infection.

scientific article

Autoantibodies and human leucocyte antigen class II in first-degree family members of Mexican-American type 1 diabetic patients

scientific article

Autoantibodies in nonobese diabetic mice immunoprecipitate 64,000-Mr islet antigen

scientific article published on 01 November 1988

Autoantibodies to pancreatic islet cells and insulin in IDDM families: the GAW5 data

scientific article

Autoantibodies to the extracellular domain of the calcium sensing receptor in patients with acquired hypoparathyroidism

scientific article published on February 1996

Autoantibody epitope mapping of the 21-hydroxylase antigen in autoimmune Addison's disease.

scientific article

Autoantigens in insulin-dependent diabetes mellitus: molecular cloning and characterization of human IA-2 beta

scientific article published on July 1, 1997

Autoimmune Addison's disease

scientific article published on 01 January 1993

Autoimmune diatheses and T lymphocyte immunoincompetences in BB rats

scientific article published on 01 July 1983

Autoimmune diseases of the adrenal glands, parathyroid glands, gonads, and hypothalamic-pituitary axis

scientific article published on September 1991

Autoimmunity in South Indian patients with IDDM

scientific article published on 01 July 1986

Autoimmunity in insulin-dependent diabetes mellitus: its detection and prevention

scientific article published on January 1988

Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus

scientific article

Autosomal dominant hypoparathyroidism with variable, age-dependent severity

scientific article published in September 1983

Basal insulin requirements on continuous subcutaneous insulin infusion during the first 12 months after diagnosis of type 1 diabetes mellitus

scientific article

Bovine albumin antibodies in NOD mice

scientific article published on 01 October 1987

CD5+ B lymphocytes in high-risk islet cell antibody-positive and newly diagnosed IDDM subjects

scientific article published on 01 October 1991

Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes

scientific article

Characterization of insulin resistance syndrome in children and young adults. When to screen for prediabetes?

scientific article published in September 2007

Childhood obesity and insulin resistance

scientific article published in January 2007

Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines

scientific article

Clinical and molecular aspects of autoimmune endocrine disease

scientific article published on January 1, 1992

Comparison of islet autoantibodies in 'pre-diabetes' and recommendations for screening

scientific article published on 01 April 1990

Competitive insulin autoantibody assay. Prospective evaluation of subjects at high risk for development of type I diabetes mellitus

scientific article published on 01 November 1987

Complement-fixing islet-cell antibodies: a separate species?

scientific article published on May 24, 1980

Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8

scientific article

Congenital pancreatic hypoplasia: a syndrome of exocrine and endocrine pancreatic insufficiency

scientific article published on 01 September 1986

Criteria for immune trials in type I diabetes

scientific article

Cryptic epitope and autoimmunity

scientific article published on 01 December 1998

Defective inducer T-cell function before the onset of insulin-dependent diabetes mellitus

scientific article published on 01 February 1991

Development of IDDM after donating kidney to diabetic sibling

scientific article published on 01 August 1990

Dietary protein restriction reduces the frequency and delays the onset of insulin dependent diabetes in BB rats

scientific article published on 01 January 1988

Different HLA haplotypes in Mexican Americans with IDDM.

scientific article published in July 1989

Different outcomes of neonatal thyroid function after Graves' disease in pregnancy: patient reports and literature review

scientific article

Early diagnosis and specific treatment of insulin-dependent diabetes

scientific article published on November 1993

Effect of metformin and rosiglitazone in a prepubertal boy with Alström syndrome

scientific article published in September 2007

Effect of oral and intravenous insulin and glutamic acid decarboxylase in NOD mice

scientific article published on 01 January 1997

Expression of GAD65 and islet cell antibody (ICA512) autoantibodies among cytoplasmic ICA+ relatives is associated with eligibility for the Diabetes Prevention Trial-Type 1.

scientific article published in August 2001

Failure to transfer diabetes mellitus from man to mouse

scientific article

Familial diabetes mellitus

scientific article published on February 1, 1988

Family Cell Lines Available for Research—An Endangered Resource?

scientific article published on September 1, 1997

GAD65 autoantibodies increase the predictability but not the sensitivity of islet cell and insulin autoantibodies for developing insulin dependent diabetes mellitus

scientific article published on 01 December 1994

Gastric parietal cell and other autoantibodies in the BB rat

scientific article published on 01 April 1982

Genetic Marker Associations With Proliferative Retinopathy in Persons Diagnosed With Diabetes Before 30 yr of age

scientific article published on 01 July 1992

Glycerol intolerance in a child with intermittent hypoglycemia

scientific article published on January 1, 1975

HERV-K10s and immune-mediated (type 1) diabetes

scientific article published in October 1998

HLA haplotype sharing and proband genotype in IDDM

scientific article published on 01 January 1986

HLA in American blacks with juvenile diabetes.

scientific article published in July 1980

HLA-DR and the 5' insulin gene polymorphism in insulin-dependent diabetes

scientific article published on December 1991

HLA-DR3 and DR4 and their relation to the incidence and progression of diabetic retinopathy1 1The authors have no proprietary interest in any of the products mentioned in this study

article

HLA-DRB1*08, DRB1*03/DRB3*0101, and DRB3*0202 are susceptibility genes for Graves' disease in North American Caucasians, whereas DRB1*07 is protective

scientific article

High risk HLA-DR/DQ genotypes for IDD confer susceptibility to autoantibodies but DQB1*0602 does not prevent them.

scientific article

Human leukocyte interferon treatment of two children with insulin dependent diabetes

scientific article published on August 1, 1981

Hypercholesterolemia. A common problem in Florida school-age children and adolescents

scientific article published on January 1991

IA-2 and IA-2 beta are major autoantigens in IDDM and the precursors of the 40 kDa and 37 kDa tryptic fragments

scientific article published on 01 October 1996

IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus

scientific article published on June 1996

Identification and characterization of glima 38, a glycosylated islet cell membrane antigen, which together with GAD65 and IA2 marks the early phases of autoimmune response in type 1 diabetes.

scientific article published on June 1996

Identification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragment

scientific article

Identification of insulin-dependent diabetes mellitus before the onset of clinical symptoms

scientific article published on 01 February 1988

Immune-mediated disease and secondary failure to oral therapy in type 2 diabetes mellitus

scientific article published in January 2004

Immunization therapies in the prevention of diabetes

scientific article published on 01 June 1997

Immunosuppression with azathioprine and prednisone in recent-onset insulin-dependent diabetes mellitus

scientific article published on 01 September 1988

Immunosuppressive therapy in insulin dependent diabetes

scientific article published on 01 June 1987

Immunotherapy at clinical diagnosis of insulin-dependent diabetes: an approach still worth considering

scientific article published on 01 April 1993

Immunotherapy in pre-type 1 diabetes mellitus

scientific article published on 01 December 1990

Improved specificity of ICA assays in the Fourth International Immunology of Diabetes Serum Exchange Workshop

scientific article published on December 1, 1992

Increased T lymphocytes bearing the gamma-delta T cell receptor in subjects at high risk for insulin dependent diabetes

scientific article published on 01 December 1991

Inherited susceptibility to autoimmune Addison's disease is linked to human leukocyte antigens-DR3 and/or DR4, except when associated with type I autoimmune polyglandular syndrome

scientific article published on 01 March 1986

Inherited susceptibility to insulin-dependent diabetes is associated with HLA-DR1, while DR5 is protective

scientific article published on 01 January 1988

Initial pathogenic events in IDDM.

scientific article published on April 1989

Insulin autoantibodies in pre-diabetes

scientific article published on 01 January 1988

Insulin dependent diabetes 1991

scientific article published on November 1, 1991

Insulin dependent diabetes: inherited susceptibility, natural history and intervention trials

scientific article published on February 1987

Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-gamma transcription

scientific article

Insulin pump therapy from the time of diagnosis of type 1 diabetes

scientific article published in December 2006

Insulin receptor autoimmunity and insulin resistance

scientific article published in April 2008

Insulin resistance syndrome in children

scientific article

Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups

scientific article published on 01 August 1997

Insulin-like growth factor binding protein-1 to screen for insulin resistance in children

scientific article published in February 2007

Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy

scientific article published on 01 August 1990

Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes

scientific article published on 07 July 2008

Intervention therapies for insulin-dependent diabetes

scientific article published on January 1993

Intervention to delay the onset of diabetes mellitus in very young siblings of children with type 1 diabetes mellitus

scientific article

Intrafamilial and case-control association analysis of D2S152 in insulin-dependent diabetes

scientific article

Is insulin-dependent diabetes mellitus a preventable disease?

scientific article published on September 1987

Islet cell and other organ-specific antibodies in U.S. Caucasians and Blacks with insulin-dependent diabetes mellitus

scientific article published on 01 August 1980

Islet cell autoantigens in insulin-dependent diabetes

scientific article published on October 1993

Islet cell cytoplasmic autoantibody reactivity to glutamate decarboxylase in insulin-dependent diabetes

scientific article published in January 1993

Lack of immune responsiveness to bovine serum albumin in insulin-dependent diabetes

scientific article published on 01 December 1993

Large Islets, Beta-Cell Proliferation, and a Glucokinase Mutation

scientific article published on 8 April 2010

Limited joint mobility in childhood diabetes: family studies

scientific article published on 01 July 1983

Limited joint mobility in diabetes mellitus of childhood: natural history and relationship to growth impairment

scientific article published on 01 November 1982

Lymphocyte subsets and activation in prediabetes

scientific article published on 01 December 1986

Maturity-onset diabetes of youth in black Americans

scientific article

Multiple autoantibodies as predictors of Type 1 diabetes in a general population

scientific article published on 11 June 2003

Multiple immuno-regulatory defects in type-1 diabetes

scientific article

NKT cell defects in NOD mice suggest therapeutic opportunities

scientific article published in November 2002

NKT cells and type-1 diabetes and the "hygiene hypothesis" to explain the rising incidence rates

scientific article

No evidence for serological autoimmunity to islet cell heat shock proteins in insulin dependent diabetes

scientific article

No primary association between the 308 polymorphism in the tumor necrosis factor alpha promoter region and insulin-dependent diabetes mellitus

scientific article published on 01 February 1996

Only multiple autoantibodies to islet cells (ICA), insulin, GAD65, IA-2 and IA-2beta predict immune-mediated (Type 1) diabetes in relatives

scientific article published on 01 June 1999

Oral insulin therapy to prevent progression of immune-mediated (type 1) diabetes

scientific article published on 01 December 2004

Pancreatic Alpha Cell Autoantibodies and Glucagon Response to Arginine

scientific article published on 01 May 1984

Paternally transmitted IDDM2 influences diabetes susceptibility despite biallelic expression of the insulin gene in human pancreas

scientific article published in February 1996

Polyclonal nature of islet cell antibodies in insulin-dependent diabetes

scientific article published on January 1988

Prediabetic markers in children with stress hyperglycemia

scientific article

Predictive value of gastric parietal cell autoantibodies as a marker for gastric and hematologic abnormalities associated with insulin-dependent diabetes

scientific article published on 01 December 1982

Preferential transmission of diabetic alleles within the HLA gene complex

scientific article published on November 1986

Preservation of C-peptide secretion in subjects at high risk of developing type 1 diabetes mellitus--a new surrogate measure of non-progression?

scientific article

Progeria: Insulin resistance and hyperglycemia

scientific article published on 01 March 1983

Resting energy expenditure in insulin resistance falls with decompensation of insulin secretion in obese children

scientific article published in April 2008

Restriction fragment length polymorphism (RFLP) heterogeneity of HLA-DQ beta genes associated with DNA fragment identical to the DR1-beta DNA structure

scientific article published on 01 September 1991

Restriction-fragment-length polymorphisms of 5'-flanking region of insulin I gene in BB and other rat strains. Absence of association with IDDM.

scientific article published in February 1987

Role of autoimmunity in insulinopenia and carbohydrate derangements associated with cystic fibrosis

scientific article published in March 1988

Screening strategies for the identification of multiple antibody-positive relatives of individuals with type 1 diabetes

scientific article published on 01 January 2003

Solitary central maxillary incisor associated with precocious puberty and hypothalamic hamartoma

scientific article published on 01 December 1982

Ten-year prognosis of impaired glucose tolerance in siblings of patients with insulin-dependent diabetes

scientific article published on 01 May 1982

The Fourth International Serum Exchange Workshop to standardize cytoplasmic islet cell antibodies. The Immunology and Diabetes Workshops and Participating Laboratories.

scientific article published in July 1991

The Fourth International Workshop on the Standardisation of Insulin Autoantibody Workshop

scientific article published in October 1990

The Gene Responsible for Autoimmune Polyglandular Syndrome Type 1 Maps to Chromosome 21q22.3 in US Patients

scientific article published on 01 April 1998

The Pathogenesis, Prediction, and Prevention of Insulin-Dependent Diabetes Mellitus

scientific article published on June 1, 1992

The diabetogenic effects of streptozotocin in mice are prolonged and inversely related to age

scientific article published on 01 September 1981

The human leukocyte antigen HLA DRB3*020/DQA1*0501 haplotype is associated with Graves' disease in African Americans

article by Q Y Chen et al published April 2000 in The Journal of Clinical Endocrinology and Metabolism

The natural history and predictive value of Mr 64,000 autoantibodies for insulin-dependent diabetes mellitus

scientific article published on 01 April 1990

The pathogenesis of insulin-dependent diabetes mellitus

scientific article published on 01 November 1994

The predictability of insulin-dependent diabetes mellitus

scientific article published on January 1988

The relationship between humoral and cellular immunity to IA-2 in IDDM

scientific article published on 01 April 1998

The relationship between immune-mediated Type 1 diabetes mellitus and ethnicity

scientific article published in January 2004

The role of tyrosinase in autoimmune vitiligo

scientific article published on 01 October 1994

The temporal association between gamma delta T cells and the natural history of insulin-dependent diabetes

scientific article published on 01 February 1993

Thymosin and the spontaneously diabetic BB rat.

scientific article published on January 1988

Thyroid autoimmunity in insulin-dependent diabetes mellitus: The case for routine screening

scientific article published on September 1, 1981

Thyroid disease in young diabetics

scientific article published on 01 August 1982

Thyroid hormone abnormalities at diagnosis of insulin-dependent diabetes mellitus in children

scientific article published on 01 August 1984

Thyroid, gastric, and adrenal autoimmunities associated with insulin-dependent diabetes mellitus

scientific article published in September 1985

Type I insulin dependent diabetes: an autoimmune disease that can be arrested or prevented with immunotherapy?

scientific article

Whole-exome sequencing identifies novel LEPR mutations in individuals with severe early onset obesity

scientific article published on 15 October 2013