List of works - Mortimer Poncz

A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation

scientific article

ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 2. Pathogenicity in an animal model

scientific article

Antibodies associated with heparin-induced thrombocytopenia (HIT) inhibit activated protein C generation: new insights into the prothrombotic nature of HIT ⬇️

scientific article published on July 19, 2011

Atomic description of the immune complex involved in heparin-induced thrombocytopenia

scientific article

Biocompatible coupling of therapeutic fusion proteins to human erythrocytes

scientific article published on 01 February 2018

Defining a second epitope for heparin-induced thrombocytopenia/thrombosis antibodies using KKO, a murine HIT-like monoclonal antibody

scientific article

Determinants of PF4/heparin immunogenicity

scientific article

Dynamic antibody-binding properties in the pathogenesis of HIT.

scientific article

Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia

scientific article published on 18 June 2018

Endothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopenia

scientific article

Heparin-induced thrombocytopenia: an autoimmune disorder regulated through dynamic autoantigen assembly/disassembly

scientific article

ICAM-1-targeted thrombomodulin mitigates tissue factor-driven inflammatory thrombosis in a human endothelialized microfluidic model

scientific article published on 08 August 2017

Molecular and cellular pathogenesis of heparin-induced thrombocytopenia (HIT)

scientific article published on 10 August 2018

Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia ⬇️

scientific article published on August 19, 2010

PF4/heparin complexes are T cell-dependent antigens

scientific article

Platelet Factor 4 Inhibits and Enhances HIV-1 Infection in a Concentration-Dependent Manner by Modulating Viral Attachment

scientific article published on 05 February 2016

Platelet factor 4 enhances the binding of oxidized low-density lipoprotein to vascular wall cells

scientific article

Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia

scientific article

Platelet-Specific Chemokines Contribute to the Pathogenesis of Acute Lung Injury

scientific article published on 18 October 2016

Platelet-delivered ADAMTS13 inhibits arterial thrombosis and prevents thrombotic thrombocytopenic purpura in murine models.

scientific article

Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia

scientific article published on 22 November 2016

Role of monocytes and endothelial cells in heparin-induced thrombocytopenia

scientific article

Role of platelet surface PF4 antigenic complexes in heparin-induced thrombocytopenia pathogenesis: diagnostic and therapeutic implications

scientific article

T2 magnetic resonance: a diagnostic platform for studying integrated hemostasis in whole blood--proof of concept.

scientific article

Targeting recombinant thrombomodulin fusion protein to red blood cells provides multifaceted thromboprophylaxis

scientific article

The antigenic complex in HIT binds to B-cells via complement and complement receptor 2 (CD21).

scientific article

The role of surface PF4: glycosaminoglycan complexes in the pathogenesis of heparin-induced thrombocytopenia (HIT).

scientific article

Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia

scientific article

List of works by Mortimer Poncz

A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation

ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 2. Pathogenicity in an animal model

Antibodies associated with heparin-induced thrombocytopenia (HIT) inhibit activated protein C generation: new insights into the prothrombotic nature of HIT ⬇️

Atomic description of the immune complex involved in heparin-induced thrombocytopenia

Biocompatible coupling of therapeutic fusion proteins to human erythrocytes

Defining a second epitope for heparin-induced thrombocytopenia/thrombosis antibodies using KKO, a murine HIT-like monoclonal antibody

Determinants of PF4/heparin immunogenicity

Dynamic antibody-binding properties in the pathogenesis of HIT.

Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia

Endothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia: an autoimmune disorder regulated through dynamic autoantigen assembly/disassembly

ICAM-1-targeted thrombomodulin mitigates tissue factor-driven inflammatory thrombosis in a human endothelialized microfluidic model

Molecular and cellular pathogenesis of heparin-induced thrombocytopenia (HIT)

Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia ⬇️

PF4/heparin complexes are T cell-dependent antigens

Platelet Factor 4 Inhibits and Enhances HIV-1 Infection in a Concentration-Dependent Manner by Modulating Viral Attachment

Platelet factor 4 enhances the binding of oxidized low-density lipoprotein to vascular wall cells

Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia

Platelet-Specific Chemokines Contribute to the Pathogenesis of Acute Lung Injury

Platelet-delivered ADAMTS13 inhibits arterial thrombosis and prevents thrombotic thrombocytopenic purpura in murine models.

Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia

Role of monocytes and endothelial cells in heparin-induced thrombocytopenia

Role of platelet surface PF4 antigenic complexes in heparin-induced thrombocytopenia pathogenesis: diagnostic and therapeutic implications

T2 magnetic resonance: a diagnostic platform for studying integrated hemostasis in whole blood--proof of concept.

Targeting recombinant thrombomodulin fusion protein to red blood cells provides multifaceted thromboprophylaxis

The antigenic complex in HIT binds to B-cells via complement and complement receptor 2 (CD21).

The role of surface PF4: glycosaminoglycan complexes in the pathogenesis of heparin-induced thrombocytopenia (HIT).

Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia