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List of works by Andrzej Bartke

17α-Estradiol promotes ovarian aging in growth hormone receptor knockout mice, but not wild-type littermates

scientific article published on 04 November 2019

17α-estradiol modulates IGF1 and hepatic gene expression in a sex-specific manner

scientific article published on 28 August 2020

A Long-lived Mouse Lacking Both Growth Hormone and Growth Hormone Receptor: A New Animal Model for Aging Studies.

scientific article published on 29 September 2016

A novel insight into aging: are there pluripotent very small embryonic-like stem cells (VSELs) in adult tissues overtime depleted in an Igf-1-dependent manner?

scientific article published in November 2010

A summary of the Proceedings of the Ninth International Symposium on the Neurobiology and Neuroendocrinology of Aging Bregenz, Austria, July 20-25, 2008.

scientific article published on 15 August 2008

A summary of the proceedings of the eighth international symposium on the neurobiology and neuroendocrinology of aging.

scientific article published on 17 October 2006

Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan

scientific article

Additive regulation of hepatic gene expression by dwarfism and caloric restriction.

scientific article

Adipocytokines and lipid levels in Ames dwarf and calorie-restricted mice

scientific article published on 01 April 2006

Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice.

scientific article published on 8 March 2007

Adiponectin in mice with altered GH action: links to insulin sensitivity and longevity?

scientific article published on 25 February 2013

Adult neurogenesis in the hippocampus of long-lived mice during aging

scientific article published in February 2007

Age-related alterations in pituitary and testicular functions in long-lived growth hormone receptor gene-disrupted mice

scientific article published on 13 September 2007

Age-related cataract progression in five mouse models for anti-oxidant protection or hormonal influence

scientific article published in September 2005

Age. Introduction

scientific article published on June 2006

Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis

scientific article published on 14 November 2019

Aging: all in the head?

scientific article published on 01 September 2007

Alcohol suppresses insulin-like growth factor-1 gene expression in prepubertal transgenic female mice overexpressing the bovine growth hormone gene

scientific article published in November 2002

Alterations in oxidative, inflammatory and apoptotic events in short-lived and long-lived mice testes

scientific article published on 23 January 2016

Alterations in oxygen consumption, respiratory quotient, and heat production in long-lived GHRKO and Ames dwarf mice, and short-lived bGH transgenic mice

scientific article published on 13 March 2009

Altered structure and function of adipose tissue in long-lived mice with growth hormone-related mutations

scientific article published on 21 March 2017

Ames dwarf (Prop1(df)/Prop1(df)) mice display increased sensitivity of the major GH-signaling pathways in liver and skeletal muscle

scientific article published on 21 December 2009

Ames hypopituitary dwarf mice demonstrate imbalanced myelopoiesis between bone marrow and spleen

scientific article published on 28 March 2015

Amyloid Beta-Related Alterations to Glutamate Signaling Dynamics During Alzheimer's Disease Progression

scientific article published on 01 January 2019

Analysis of Different Approaches for the Selection of Reference Genes in RT-qPCR Experiments: A Case Study in Skeletal Muscle of Growing Mice

scientific article

Anti-aging interventions affect lifespan variability in sex, strain, diet and drug dependent fashion

scientific article published on 01 June 2019

Attenuation of epidermal growth factor (EGF) signaling by growth hormone (GH).

scientific article

Biological approaches to mechanistically understand the healthy life span extension achieved by calorie restriction and modulation of hormones

scientific article

Body composition of prolactin-, growth hormone, and thyrotropin-deficient Ames dwarf mice

scientific article

Brown Adipose Tissue Function Is Enhanced in Long-Lived, Male Ames Dwarf Mice

scientific article published on 14 October 2016

C-reactive protein and glucose regulation in familial longevity

scientific article published on 19 January 2011

Caloric restriction and growth hormone receptor knockout: effects on expression of genes involved in insulin action in the heart

scientific article

Caloric restriction results in decreased expression of peroxisome proliferator-activated receptor superfamily in muscle of normal and long-lived growth hormone receptor/binding protein knockout mice

scientific article

Can FSH influence longevity?

scientific article published on 30 August 2017

Can Growth Hormone (GH) Accelerate Aging? Evidence from GH-Transgenic Mice ⬇️

scientific article published on October 1, 2003

Changes of Ovarian microRNA Profile in Long-Living Ames Dwarf Mice during Aging

scientific article

Circulating blood leukocyte gene expression profiles: effects of the Ames dwarf mutation on pathways related to immunity and inflammation

scientific article

Comment on: Kloting et al. (2008) Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth: Diabetes 57:2074-2082.

scientific article

Corrigendum

Corrigendum to “What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?” [Mechanisms of Ageing and Development 126 (2005) 421–429]

article

Declining sperm counts and increases in testicular cancer: a legacy of the cold war?

scientific article published on 18 December 2008

Decreased expression level of apoptosis-related genes and/or proteins in skeletal muscles, but not in hearts, of growth hormone receptor knockout mice

scientific article published on February 2011

Decreased levels of proapoptotic factors and increased key regulators of mitochondrial biogenesis constitute new potential beneficial features of long-lived growth hormone receptor gene-disrupted mice.

scientific article

Decreased thyroid follicle size in dwarf mice may suggest the role of growth hormone signaling in thyroid growth regulation

scientific article

Delayed and accelerated aging share common longevity assurance mechanisms

scientific article

Delayed occurrence of fatal neoplastic diseases in ames dwarf mice: correlation to extended longevity

scientific article published on 01 April 2003

Deletion of growth hormone receptor gene but not visceral fat removal decreases expression of apoptosis-related genes in the kidney-potential mechanism of lifespan extension

scientific article published on 23 March 2011

Desensitization of the JAK2/STAT5 GH signaling pathway associated with increased CIS protein content in liver of pregnant mice

scientific article published on 17 May 2005

Diet and aging

scientific article published on 01 August 2008

Diet-induced insulin resistance elevates hippocampal glutamate as well as VGLUT1 and GFAP expression in AβPP/PS1 mice

scientific article published on 03 January 2019

Dietary restriction and life-span

scientific article published in June 2002

Differential Fasting Plasma Glucose and Ketone Body Levels in GHRKO versus 3xTg-AD Mice: A Potential Contributor to Aging-Related Cognitive Status?

scientific article

Differential effects of early-life nutrient restriction in long-lived GHR-KO and normal mice.

scientific article published on 18 May 2017

Direct and indirect effects of growth hormone receptor ablation on liver expression of xenobiotic metabolizing genes

scientific article published on 13 August 2013

Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity

scientific article

Divergent effects of caloric restriction on gene expression in normal and long-lived mice.

scientific article published in August 2004

Do Ames dwarf and calorie-restricted mice share common effects on age-related pathology?

scientific article

Do altered energy metabolism or spontaneous locomotion 'mediate' decelerated senescence?

scientific article published on 26 February 2015

Downregulation of the ACE2/Ang-(1-7)/Mas axis in transgenic mice overexpressing GH.

scientific article published on 22 April 2014

Duration of rapamycin treatment has differential effects on metabolism in mice

scientific article published on March 2013

Dwarf Mice and Aging

scientific article published in February 2018

EFFECT OF CALORIC RESTRICTION AND RAPAMYCIN ON OVARIAN AGING IN MICE

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

Early Life Events can Shape Aging and Longevity

Early life events can shape aging and longevity

scientific article published on January 2015

Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice

scientific article

Effect of Ames dwarfism and caloric restriction on spontaneous DNA mutation frequency in different mouse tissues

scientific article published on 13 May 2008

Effect of caloric restriction and rapamycin on ovarian aging in mice

scientific article published on 29 July 2019

Effect of every other day feeding diet on gene expression in normal and in long-lived Ames dwarf mice

scientific article published in June 2005

Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries.

scientific article

Effects of caloric restriction and growth hormone resistance on insulin-related intermediates in the skeletal muscle

scientific article published in January 2007

Effects of caloric restriction and growth hormone resistance on the expression level of peroxisome proliferator-activated receptors superfamily in liver of normal and long-lived growth hormone receptor/binding protein knockout mice

scientific article published on 01 November 2005

Effects of caloric restriction on insulin pathway gene expression in the skeletal muscle and liver of normal and long-lived GHR-KO mice

scientific article published in August 2005

Effects of dietary restriction on the expression of insulin-signaling-related genes in long-lived mutant mice

scientific article published on January 2007

Effects of every-other-day feeding on prolactin regulatory mechanism in transgenic human growth hormone mice

scientific article

Effects of growth hormone and thyroxine replacement therapy on insulin signaling in Ames dwarf mice

scientific article

Effects of long-term caloric restriction on early steps of the insulin-signaling system in mouse skeletal muscle

scientific article published in January 2005

Effects of long-term caloric restriction on glucose homeostasis and on the first steps of the insulin signaling system in skeletal muscle of normal and Ames dwarf (Prop1df/Prop1df) mice

scientific article published in January 2005

Effects of mild calorie restriction on reproduction, plasma parameters and hepatic gene expression in mice with altered GH/IGF-I axis

scientific article published on 20 February 2007

Effects of rapamycin on growth hormone receptor knockout mice.

scientific article

Effects of soy protein and soy phytochemicals on mammary tumor development in female transgenic mice overexpressing human pituitary growth hormone

scientific article published in January 2005

Endocrine regulation of heat shock protein mRNA levels in long-lived dwarf mice

scientific article published on 08 April 2009

Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice

scientific article published on 29 August 2008

Energy Metabolism and Aging

scientific article published on 28 August 2020

Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging.

scientific article published on 21 May 2016

Erratum to: Preservation of blood glucose homeostasis in slow-senescing somatotrophism-deficient mice subjected to intermittent fasting begun at middle or old age.

scientific article published on 9 August 2014

Evidence That Growth Hormone Exerts a Feedback Effect on Stomach Ghrelin Production and Secretion ⬇️

scientific article published on 01 October 2003

Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice

scientific article published in March 2005

Exposure to growth hormone is associated with hepatic up-regulation of cPLA2α and COX

scientific article published on 04 April 2020

Expression of apoptosis-related genes in liver-specific growth hormone receptor gene-disrupted mice is sex dependent

scientific article

Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions.

scientific article

Female PAPP-A knockout mice are resistant to metabolic dysfunction induced by high-fat/high-sucrose feeding at middle age.

scientific article published on 8 May 2015

Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress.

scientific article published on 8 February 2005

Fibroblasts from long-lived mutant mice show diminished ERK1/2 phosphorylation but exaggerated induction of immediate early genes

scientific article

Food Restriction, Hormones, Genes and Aging

article

From White to Brown - Adipose Tissue Is Critical to the Extended Lifespan and Healthspan of Growth Hormone Mutant Mice

scientific article published on 01 January 2019

Functionally enhanced brown adipose tissue in Ames dwarf mice

scientific article published on 21 December 2016

GH and IGF1: Roles in Energy Metabolism of Long-Living GH Mutant Mice ⬇️

scientific article published on March 30, 2012

GH and ageing: Pitfalls and new insights

scientific article published on 24 February 2017

GH modulates hepatic epidermal growth factor signaling in the mouse.

scientific article

GH/STAT5 signaling during the growth period in livers of mice overexpressing GH.

scientific article published on 17 February 2015

Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver

scientific article

Gene expression patterns in calorically restricted mice: partial overlap with long-lived mutant mice

scientific article published in November 2002

Genetic differences and longevity-related phenotypes influence lifespan and lifespan variation in a sex-specific manner in mice

scientific article published on 26 October 2020

Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis

scientific article

Growth Hormone Deficiency: Health and Longevity

scientific article published on 01 April 2019

Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence

scientific article published on 10 February 2016

Growth Hormone and Aging: New Findings

scientific article published in 2021

Growth Hormone and Aging: Updated Review

scientific article published on 11 May 2018

Growth hormone abolishes beneficial effects of calorie restriction in long-lived Ames dwarf mice.

scientific article

Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice.

scientific article

Growth hormone actions during development influence adult phenotype and longevity

scientific article published on 2 January 2016

Growth hormone and aging

scientific article published on 01 October 2020

Growth hormone and aging: a challenging controversy

scientific article

Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice

scientific article

Growth hormone modulation of EGF-induced PI3K-Akt pathway in mice liver

scientific article published on 14 October 2011

Growth hormone upregulates the pro-tumorigenic galectin 1 in mouse liver

scientific article published on 01 August 2019

Growth hormone, inflammation and aging

scientific article

Growth hormone, insulin and aging: the benefits of endocrine defects

scientific article

Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice

scientific article

Hallmarks of Testicular Aging: The Challenge of Anti-Inflammatory and Antioxidant Therapies Using Natural and/or Pharmacological Compounds to Improve the Physiopathological Status of the Aged Male Gonad

scientific article published on 10 November 2021

Healthspan and longevity can be extended by suppression of growth hormone signaling

scientific article published on 24 February 2016

Healthy Aging: Is Smaller Better? – A Mini-Review ⬇️

scientific article published on January 18, 2012

Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone

scientific article published on 21 February 2013

Histological changes of testes in growth hormone transgenic mice with high plasma level of GH and insulin-like growth factor-1.

scientific article published on 8 September 2015

Human placental growth hormone causes severe insulin resistance in transgenic mice

scientific article published in March 2002

Humoral immune response in mice over-expressing or deficient in growth hormone.

scientific article published in July 2002

Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production

scientific article

IGF-I regulates the age-dependent signaling peptide humanin.

scientific article

Impact of Growth Hormone-Related Mutations on Mammalian Aging

scholarly article by Andrzej Bartke & Nana Quainoo published 2018 in Frontiers in Genetics

Impact of growth hormone resistance on female reproductive function: new insights from growth hormone receptor knockout mice

scientific article published in October 2002

Impact of reduced insulin-like growth factor-1/insulin signaling on aging in mammals: novel findings

scientific article published on 11 March 2008

Impact papers on aging in 2009.

scientific article

In vivo analysis of gene expression in long-lived mice lacking the pregnancy-associated plasma protein A (PappA) gene

scientific article

Increased environmental temperature normalizes energy metabolism outputs between normal and Ames dwarf mice

scientific article published on 01 October 2018

Increased in vivo phosphorylation of insulin receptor at serine 994 in the liver of obese insulin-resistant Zucker rats

scientific article published in September 2004

Increased neurogenesis in dentate gyrus of long-lived Ames dwarf mice

scientific article published on 24 November 2004

Inflammatory and Glutamatergic Homeostasis Are Involved in Successful Aging

scientific article published on 22 February 2015

Insulin and aging

scientific article

Insulin resistance and cognitive aging in long-lived and short-lived mice.

scientific article

Insulin sensitivity as a key mediator of growth hormone actions on longevity

scientific article published on 20 March 2009

Insulin signaling cascade in the hearts of long-lived growth hormone receptor knockout mice: effects of calorie restriction

scientific article

Insulin-Like Growth Factor 1 and Mammalian Aging ⬇️

scientific article published on April 24, 2002

Integrated metabolomics reveals altered lipid metabolism in adipose tissue in a model of extreme longevity

scientific article published on 06 July 2020

Interaction of growth hormone and calorie restriction

scientific article published on 01 November 2006

Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging.

scientific article

Interventions to Slow Aging in Humans: Are We Ready?

scientific article

Intestinal immunity in hypopituitary dwarf mice: effects of age.

scientific article published on 2 March 2018

Is altered expression of hepatic insulin-related genes in growth hormone receptor knockout mice due to GH resistance or a difference in biological life spans?

scientific article published on 25 August 2009

Is growth hormone deficiency a beneficial adaptation to aging? Evidence from experimental animals

scientific article

KENT AND KLEEMEIER AWARD LECTURES

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

Key regulators of mitochondrial biogenesis are increased in kidneys of growth hormone receptor knockout (GHRKO) mice

scientific article published on 14 July 2011

Life extension in the dwarf mouse

scientific article published in January 2004

Lifespan of long-lived growth hormone receptor knockout mice was not normalized by housing at 30°C since weaning

scientific article published on 28 February 2020

Links between growth hormone and aging.

scientific article

Liver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles

scientific article published on 11 February 2014

Local expression of GH and IGF-1 in the hippocampus of GH-deficient long-lived mice

scientific article published in June 2005

Long-lived Ames dwarf mice: Oxidative damage to mitochondrial DNA in heart and brain.

scientific article

Long-lived Klotho mice: new insights into the roles of IGF-1 and insulin in aging

scientific article published on 03 February 2006

Long-lived crowded-litter mice exhibit lasting effects on insulin sensitivity and energy homeostasis

scientific article

Long-lived growth hormone receptor knockout mice show a delay in age-related changes of body composition and bone characteristics.

scientific article

Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction

scientific article published on 21 October 2004

Long-lived hypopituitary Ames dwarf mice are resistant to the detrimental effects of high-fat diet on metabolic function and energy expenditure

scientific article published on 17 March 2016

Long-living growth hormone receptor knockout mice: potential mechanisms of altered stress resistance

scientific article published on 15 July 2008

Longevity is impacted by growth hormone action during early postnatal period

scientific article

Male and female gonadal ageing: its impact on health span and life span

scientific article published in July 2021

Measuring aging rates of mice subjected to caloric restriction and genetic disruption of growth hormone signaling

scientific article published on 7 March 2016

Metabolic Syndrome and Skin Diseases

scientific article published on 20 November 2019

Metabolic alterations due to caloric restriction and every other day feeding in normal and growth hormone receptor knockout mice

scientific article published on 05 July 2013

Metabolic characteristics of long-lived mice ⬇️

scientific article published on December 13, 2012

Metabolic effects of intra-abdominal fat in GHRKO mice

scientific article published on 28 November 2011

Metformin treatment of juvenile mice alters aging-related developmental and metabolic phenotypes

scientific article published in January 2022

MicroRNA regulation in Ames dwarf mouse liver may contribute to delayed aging

scientific article

Mild calorie restriction does not affect testosterone levels and testicular gene expression in mutant mice

scientific article published on 01 September 2007

Miller time ⬇️

scientific article published on February 1, 2011

Minireview: role of the growth hormone/insulin-like growth factor system in mammalian aging

scientific article

Mitogenic signaling pathways in the liver of growth hormone (GH)-overexpressing mice during the growth period

scientific article published on March 2016

Morphology of ovaries in laron dwarf mice, with low circulating plasma levels of insulin-like growth factor-1 (IGF-1), and in bovine GH-transgenic mice, with high circulating plasma levels of IGF-1

scientific article published on 2 July 2012

New Directions in Research on Aging

scientific article published in April 2022

New findings in gene knockout, mutant and transgenic mice

scientific article

New findings in transgenic, gene knockout and mutant mice

scientific article published on 17 October 2006

Original Research: Metabolic alterations from early life thyroxine replacement therapy in male Ames dwarf mice are transient.

scientific article published on 13 May 2016

Ovarian transcriptome associated with reproductive senescence in the long-living Ames dwarf mice.

scientific article

PPARs in Calorie Restricted and Genetically Long-Lived Mice

scientific article published on January 2007

Parting messages from current and former editors of the Journal of Andrology.

scientific article published on 9 August 2012

Pioglitazone does not improve insulin signaling in mice with GH over-expression

scientific article published on 04 October 2013

Play, copulation, anatomy, and testosterone in gonadally intact male rats prenatally exposed to flutamide

scientific article published in September 2003

Pleiotropic effects of growth hormone signaling in aging ⬇️

scientific article published on August 17, 2011

Post‐transcriptional regulation of IGF1R by key microRNAs in long–lived mutant mice ⬇️

scientific article published on December 1, 2011

Preservation of blood glucose homeostasis in slow-senescing somatotrophism-deficient mice subjected to intermittent fasting begun at middle or old age.

scientific article

Prevention of neuromusculoskeletal frailty in slow-aging ames dwarf mice: longitudinal investigation of interaction of longevity genes and caloric restriction

scientific article

Primordial follicle reserve, DNA damage and macrophage infiltration in the ovaries of the long-living Ames dwarf mice

scientific article published on 25 January 2020

Proceedings of the seventh international symposium on the neurobiology and neuroendocrinology of aging, Bregenz, Austria, July 18-23, 2004.

scientific article published in November 2004

Progressive loss of SIRT1 with cell cycle withdrawal

scientific article

Prolactin in the male: 25 years later

scientific article published in September 2004

Prolonged Growth Hormone/Insulin/Insulin-like Growth Factor Nutrient Response Signaling Pathway as a Silent Killer of Stem Cells and a Culprit in Aging

scientific article published on 22 February 2017

Prolonged rapamycin treatment led to beneficial metabolic switch

scientific article published in May 2013

Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease

scholarly article

Puberty is delayed in male growth hormone receptor gene-disrupted mice.

scientific article published in September 2002

Rapamycin slows aging in mice

scientific article published on 01 March 2012

RasGrf1: genomic imprinting, VSELs, and aging

scientific article published in July 2011

Reduced incidence and delayed occurrence of fatal neoplastic diseases in growth hormone receptor/binding protein knockout mice

scientific article published on 19 February 2009

Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR-/- mice

scientific article

Renal pro-apoptotic proteins are reduced by growth hormone resistance but not by visceral fat removal.

scientific article published on 11 March 2011

Resistance to the Beneficial Metabolic Effects and Hepatic Antioxidant Defense Actions of Fibroblast Growth Factor 21 Treatment in Growth Hormone-Overexpressing Transgenic Mice.

scientific article published on 18 May 2015

Riluzole Attenuates Glutamatergic Tone and Cognitive Decline in AβPP/PS1 Mice

scientific article published on 26 October 2020

Sex Differences in Longevity and in Responses to Anti-Aging Interventions: A Mini-Review

scientific article

Sexual dimorphic responses of C57BL/6 mice to Fisetin or Dasatinib and Quercetin cocktail oral treatment

scientific article published on 8 November 2021

Single-gene mutations and healthy ageing in mammals

scientific article

Smaller cardiac cell size and reduced extra-cellular collagen might be beneficial for hearts of Ames dwarf mice ⬇️

scientific article published on September 1, 2010

Somatic growth, aging, and longevity

scientific article published on 29 September 2017

Somatotropic signaling: trade-offs between growth, reproductive development, and longevity

scientific article published on April 2013

Soy isoflavones modify liver free radical scavenger systems and liver parameters in Sprague-Dawley rats

scientific article published in January 2004

Special issue on the endocrinology of aging

scientific article published on 08 November 2008

Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging

scientific article

Stress resistance and aging: influence of genes and nutrition.

scientific article

Suppression of growth hormone (GH) Janus tyrosine kinase 2/signal transducer and activator of transcription 5 signaling pathway in transgenic mice overexpressing bovine GH.

scientific article published on 11 March 2004

THow diet interacts with longevity genes

scientific article published on January 2008

Tachykinins and their possible modulatory role on testicular function: a review

scientific article

Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction

scholarly article

Testosterone plus low-intensity physical training in late life improves functional performance, skeletal muscle mitochondrial biogenesis, and mitochondrial quality control in male mice

scientific article (publication date: 2012)

The consequences of altered somatotropic system on reproduction

scientific article published on 17 March 2004

The contribution of visceral fat to improved insulin signaling in Ames dwarf mice.

scientific article

The critical role of metabolic pathways in aging

scientific article

The dwarf mutation decreases high dose insulin responses in skeletal muscle, the opposite of effects in liver

scientific article published in July 2003

The effect of calorie restriction on insulin signaling in skeletal muscle and adipose tissue of Ames dwarf mice

scientific article

The effect of calorie restriction on the presence of apoptotic ovarian cells in normal wild type mice and low-plasma-IGF-1 Laron dwarf mice

scientific article published on 24 September 2013

The effect of low and high plasma levels of insulin-like growth factor-1 (IGF-1) on the morphology of major organs: studies of Laron dwarf and bovine growth hormone transgenic (bGHTg) mice.

scientific article published on 24 April 2013

The effects of aging and genotype on NMDA receptor expression in growth hormone receptor knockout (GHRKO) mice

scientific article

The effects of early-life growth hormone intervention on tissue specific histone H3 modifications in long-lived Ames dwarf mice

scientific article published on 28 December 2020

The endocrine regulation of aging by insulin-like signals

scientific article

The enigmatic role of growth hormone in age-related diseases, cognition, and longevity

scientific article published on 04 September 2019

The forgotten lactogenic activity of growth hormone: important implications for rodent studies

scientific article

The growth hormone receptor gene-disrupted mouse fails to respond to an intermittent fasting diet

scientific article published on 11 September 2009

The interconnections between somatic and ovarian aging in murine models

scientific article published on 10 October 2020

The key role of growth hormone-insulin-IGF-1 signaling in aging and cancer

scientific article

The negative effect of prolonged somatotrophic/insulin signaling on an adult bone marrow-residing population of pluripotent very small embryonic-like stem cells (VSELs).

scientific article published on 5 January 2012

The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice

scientific article published on 24 January 2013

The role of insulin-like growth factor-I in neuroendocrine function and the consequent effects on sexual maturation: inferences from animal models.

scientific article published on March 2003

The second international conference "genetics of aging and longevity".

scientific article published on May 2012

The slow-aging growth hormone receptor/binding protein gene-disrupted (GHR-KO) mouse is protected from aging-resultant neuromusculoskeletal frailty

scientific article published on 04 July 2013

The somatotropic axis and aging: Benefits of endocrine defects.

scientific article published on 16 February 2016

The somatotropic axis and aging: mechanisms and persistent questions about practical implications

scientific article

Thyroxine modifies the effects of growth hormone in Ames dwarf mice

scientific article published on April 2015

Time to talk SENS: critiquing the immutability of human aging.

scientific article

Tissue-Specific GHR Knockout Mice: Metabolic Phenotypes

scientific article

Transgenic mice overexpressing GH exhibit hepatic upregulation of GH-signaling mediators involved in cell proliferation

scientific article published on 14 May 2008

Transient early food restriction leads to hypothalamic changes in the long-lived crowded litter female mice

scientific article published on April 2015

Upregulation of the angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas receptor axis in the heart and the kidney of growth hormone receptor knock-out mice.

scientific article published on 02 September 2012

What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?

scientific article

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