List of works - Marina Boukhvalova

A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation

scientific article

A multifaceted approach to RSV vaccination

scholarly article by Jorge C G Blanco et al published 3 July 2018 in Human Vaccines & Immunotherapeutics

A recombinant anchorless respiratory syncytial virus (RSV) fusion (F) protein/monophosphoryl lipid A (MPL) vaccine protects against RSV-induced replication and lung pathology.

scientific article

Activation of interferon response through toll-like receptor 3 impacts viral pathogenesis and pulmonary toll-like receptor expression during respiratory syncytial virus and influenza infections in the cotton rat Sigmodon hispidus model

scientific article

Age-related differences in pulmonary cytokine response to respiratory syncytial virus infection: modulation by anti-inflammatory and antiviral treatment

scientific article published on 4 January 2007

Alternative Virus-Like Particle-Associated Prefusion F Proteins as Maternal Vaccines for Respiratory Syncytial Virus

scientific article published on 13 November 2019

Analysis of TLR4 polymorphic variants: new insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling

scientific article published on July 2006

Association of TLR4 polymorphisms with symptomatic respiratory syncytial virus infection in high-risk infants and young children

scientific article published on September 2007

CheA kinase and chemoreceptor interaction surfaces on CheW.

scientific article published on 18 April 2002

CheW binding interactions with CheA and Tar. Importance for chemotaxis signaling in Escherichia coli

scientific article

Comparisons of Antibody Populations in Different Pre-Fusion F VLP-Immunized Cotton Rat Dams and Their Offspring

scientific article published on 18 March 2020

Cotton rat lung transcriptome reveals host immune response to Respiratory Syncytial Virus infection

scientific article published in Scientific Reports

Cotton rat model for testing vaccines and antivirals against respiratory syncytial virus.

scientific article

Effect of aging on immunogenicity and efficacy of inactivated influenza vaccines in cotton rats Sigmodon hispidus

scientific article published on 02 July 2020

Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model.

scientific article published on 15 May 2018

Efficacy of the Herpes Simplex Virus 2 (HSV-2) Glycoprotein D/AS04 Vaccine against Genital HSV-2 and HSV-1 Infection and Disease in the Cotton Rat Sigmodon hispidus Model.

scientific article

Efficacy of trivalent inactivated influenza vaccines in the cotton rat Sigmodon hispidus model ⬇️

scientific article published on December 30, 2011

Enterovirus D-68 Infection, Prophylaxis, and Vaccination in a Novel Permissive Animal Model, the Cotton Rat (Sigmodon hispidus).

scientific article

Evaluation of the potential effects of AS03-adjuvanted A(H1N1)pdm09 vaccine administration on the central nervous system of non-primed and A(H1N1)pdm09-primed cotton rats

scientific article

Herpes Simplex Virus 1 Induces Brain Inflammation and Multifocal Demyelination in the Cotton Rat Sigmodon hispidus

scientific article published on 12 December 2019

Human metapneumovirus reinfection among children in Thailand determined by ELISA using purified soluble fusion protein

scientific article published on September 2008

Human metapneumovirus: enhanced pulmonary disease in cotton rats immunized with formalin-inactivated virus vaccine and challenged.

scientific article published on 15 May 2007

Immunization with Live Human Rhinovirus (HRV) 16 Induces Protection in Cotton Rats against HRV14 Infection

scientific article published on 31 August 2017

Improving ability of RSV microneutralization assay to detect G-specific and cross-reactive neutralizing antibodies through immortalized cell line selection

scientific article published on 28 June 2018

Inactivation of respiratory syncytial virus by zinc finger reactive compounds.

scientific article

Maternal transfer of RSV immunity in cotton rats vaccinated during pregnancy

scientific article published on 31 August 2015

Methods for monitoring dynamics of pulmonary RSV replication by viral culture and by real-time reverse transcription-PCR in vivo: Detection of abortive viral replication.

scientific article published on March 2010

Modeling Human Respiratory Viral Infections in the Cotton Rat (Sigmodon hispidus).

scientific article

Mutation of Respiratory Syncytial Virus G Protein's CX3C Motif Attenuates Infection in Cotton Rats and Primary Human Airway Epithelial Cells

scientific article published on 19 July 2019

New insights for development of a safe and protective RSV vaccine

scientific article

Novel drugs targeting Toll-like receptors for antiviral therapy

scientific article

PROPHYLACTIC ANTIBODY TREATMENT AND INTRAMUSCULAR IMMUNIZATION REDUCE INFECTIOUS HUMAN RHINOVIRUS 16 LOAD IN THE LOWER RESPIRATORY TRACT OF CHALLENGED COTTON RATS.

scientific article

Pathogenesis of human metapneumovirus lung infection in BALB/c mice and cotton rats

scientific article published on July 2005

Preclinical assessment of safety of maternal vaccination against respiratory syncytial virus (RSV) in cotton rats.

scientific article published on 14 June 2017

Prospects of antiviral and anti-inflammatory therapy for respiratory syncytial virus infection

scientific article

Respiratory syncytial virus (RSV) infection induces cyclooxygenase 2: a potential target for RSV therapy.

scientific article published in April 2005

Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2.

scientific article

Respiratory syncytial virus infects and abortively replicates in the lungs in spite of preexisting immunity

scientific article

Serum High-Mobility-Group Box 1 as a Biomarker and a Therapeutic Target during Respiratory Virus Infections

scientific article published on 13 March 2018

Species-specific transcriptomic changes upon respiratory syncytial virus infection in cotton rats

scientific article published in 2022

The TLR4 agonist, monophosphoryl lipid A, attenuates the cytokine storm associated with respiratory syncytial virus vaccine-enhanced disease.

scientific article published on 18 April 2006

The cotton rat Sigmodon hispidus model of respiratory syncytial virus infection.

scientific article published on January 2013

The cotton rat model of respiratory viral infections

scientific article published on 25 April 2009

The cotton rat: an underutilized animal model for human infectious diseases can now be exploited using specific reagents to cytokines, chemokines, and interferons.

scientific article

List of works by Marina Boukhvalova

A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation

A multifaceted approach to RSV vaccination

A recombinant anchorless respiratory syncytial virus (RSV) fusion (F) protein/monophosphoryl lipid A (MPL) vaccine protects against RSV-induced replication and lung pathology.

Activation of interferon response through toll-like receptor 3 impacts viral pathogenesis and pulmonary toll-like receptor expression during respiratory syncytial virus and influenza infections in the cotton rat Sigmodon hispidus model

Age-related differences in pulmonary cytokine response to respiratory syncytial virus infection: modulation by anti-inflammatory and antiviral treatment

Alternative Virus-Like Particle-Associated Prefusion F Proteins as Maternal Vaccines for Respiratory Syncytial Virus

Analysis of TLR4 polymorphic variants: new insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling

Association of TLR4 polymorphisms with symptomatic respiratory syncytial virus infection in high-risk infants and young children

CheA kinase and chemoreceptor interaction surfaces on CheW.

CheW binding interactions with CheA and Tar. Importance for chemotaxis signaling in Escherichia coli

Comparisons of Antibody Populations in Different Pre-Fusion F VLP-Immunized Cotton Rat Dams and Their Offspring

Cotton rat lung transcriptome reveals host immune response to Respiratory Syncytial Virus infection

Cotton rat model for testing vaccines and antivirals against respiratory syncytial virus.

Effect of aging on immunogenicity and efficacy of inactivated influenza vaccines in cotton rats Sigmodon hispidus

Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model.

Efficacy of the Herpes Simplex Virus 2 (HSV-2) Glycoprotein D/AS04 Vaccine against Genital HSV-2 and HSV-1 Infection and Disease in the Cotton Rat Sigmodon hispidus Model.

Efficacy of trivalent inactivated influenza vaccines in the cotton rat Sigmodon hispidus model ⬇️

Enterovirus D-68 Infection, Prophylaxis, and Vaccination in a Novel Permissive Animal Model, the Cotton Rat (Sigmodon hispidus).

Evaluation of the potential effects of AS03-adjuvanted A(H1N1)pdm09 vaccine administration on the central nervous system of non-primed and A(H1N1)pdm09-primed cotton rats

Herpes Simplex Virus 1 Induces Brain Inflammation and Multifocal Demyelination in the Cotton Rat Sigmodon hispidus

Human metapneumovirus reinfection among children in Thailand determined by ELISA using purified soluble fusion protein

Human metapneumovirus: enhanced pulmonary disease in cotton rats immunized with formalin-inactivated virus vaccine and challenged.

Immunization with Live Human Rhinovirus (HRV) 16 Induces Protection in Cotton Rats against HRV14 Infection

Improving ability of RSV microneutralization assay to detect G-specific and cross-reactive neutralizing antibodies through immortalized cell line selection

Inactivation of respiratory syncytial virus by zinc finger reactive compounds.

Maternal transfer of RSV immunity in cotton rats vaccinated during pregnancy

Methods for monitoring dynamics of pulmonary RSV replication by viral culture and by real-time reverse transcription-PCR in vivo: Detection of abortive viral replication.

Modeling Human Respiratory Viral Infections in the Cotton Rat (Sigmodon hispidus).

Mutation of Respiratory Syncytial Virus G Protein's CX3C Motif Attenuates Infection in Cotton Rats and Primary Human Airway Epithelial Cells

New insights for development of a safe and protective RSV vaccine

Novel drugs targeting Toll-like receptors for antiviral therapy

PROPHYLACTIC ANTIBODY TREATMENT AND INTRAMUSCULAR IMMUNIZATION REDUCE INFECTIOUS HUMAN RHINOVIRUS 16 LOAD IN THE LOWER RESPIRATORY TRACT OF CHALLENGED COTTON RATS.

Pathogenesis of human metapneumovirus lung infection in BALB/c mice and cotton rats

Preclinical assessment of safety of maternal vaccination against respiratory syncytial virus (RSV) in cotton rats.

Prospects of antiviral and anti-inflammatory therapy for respiratory syncytial virus infection

Respiratory syncytial virus (RSV) infection induces cyclooxygenase 2: a potential target for RSV therapy.

Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2.

Respiratory syncytial virus infects and abortively replicates in the lungs in spite of preexisting immunity

Serum High-Mobility-Group Box 1 as a Biomarker and a Therapeutic Target during Respiratory Virus Infections

Species-specific transcriptomic changes upon respiratory syncytial virus infection in cotton rats

The TLR4 agonist, monophosphoryl lipid A, attenuates the cytokine storm associated with respiratory syncytial virus vaccine-enhanced disease.

The cotton rat Sigmodon hispidus model of respiratory syncytial virus infection.

The cotton rat model of respiratory viral infections

The cotton rat: an underutilized animal model for human infectious diseases can now be exploited using specific reagents to cytokines, chemokines, and interferons.