List of works by Bruce W. Robinson

A Proteomic Analysis of the Malignant Mesothelioma Secretome Using iTRAQ.

scientific article published on March 2017

A molecular diagnostic test for distinguishing lung adenocarcinoma from malignant mesothelioma using cells collected from pleural effusions.

scientific article

A novel SV40 TAg transgenic model of asbestos-induced mesothelioma: malignant transformation is dose dependent

scientific article published on November 2006

Absence of germline mutations in BAP1 in sporadic cases of malignant mesothelioma.

scientific article published on 18 March 2015

Advances in malignant mesothelioma

scientific article

Agonistic anti-CD40 antibody therapy is effective against postoperative cancer recurrence and metastasis in a murine tumor model.

scientific article published on September 2013

Association of biomarker levels with severity of asbestos-related diseases

scientific article

Author's response: Inconsistent results or inconsistent methods? A plea for standardisation of biomarker sampling in mesothelioma studies.

scientific article published on 5 December 2014

Auto-antibodies to β-F1-ATPase and vimentin in malignant mesothelioma

scientific article

CD4+ T cells cross-compete for MHC class II-restricted peptide antigen complexes on the surface of antigen presenting cells.

scientific article published in April 2004

CD8alpha+ DC are not the sole subset cross-presenting cell-associated tumor antigens from a solid tumor

scientific article published on 01 June 2010

Calretinin as a blood-based biomarker for mesothelioma

scientific article

Climbing Mount Kilimanjaro in a blizzard.

scientific article published on December 2004

Combined CA125 and Mesothelin Levels for the Diagnosis of Malignant Mesothelioma

scientific article published on 23 July 2007

Combined chemoimmunotherapy of solid tumours: improving vaccines?

scientific article published on 15 August 2006

Combining immunotherapy with chemotherapy to treat cancer.

scientific article published on June 2005

Comparison of fibulin-3 and mesothelin as markers in malignant mesothelioma

scientific article

Comparison of mesothelin and fibulin-3 in pleural fluid and serum as markers in malignant mesothelioma

scientific article published on July 2015

Comparison of osteopontin, megakaryocyte potentiating factor, and mesothelin proteins as markers in the serum of patients with malignant mesothelioma

scientific article

Comparison of the diagnostic accuracy of the MSLN gene products, mesothelin and megakaryocyte potentiating factor, as biomarkers for mesothelioma in pleural effusions and serum

scientific article published on 06 August 2013

Consistent gene expression profiles in MexTAg transgenic mouse and wild type mouse asbestos-induced mesothelioma

scientific article published on 18 December 2015

Correction: genetic variants associated with increased risk of malignant pleural mesothelioma: a genome-wide association study.

scientific article published on 3 June 2015

Cranking the immunologic engine with chemotherapy: using context to drive tumor antigen cross-presentation towards useful antitumor immunity.

scientific article

Cross-priming in health and disease.

scientific article published on June 2010

Current and Future Management of Malignant Mesothelioma : A Consensus Report from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer and Mesothelioma Applied Research Foundatio

scientific article published on 25 September 2018

Current chemotherapeutic treatment of malignant pleural mesothelioma

scientific article

Cutting edge: tumor-specific CTL are constitutively cross-armed in draining lymph nodes and transiently disseminate to mediate tumor regression following systemic CD40 activation

scientific article

Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth

scientific article

Deliberately provoking local inflammation drives tumors to become their own protective vaccine site.

scientific article published on 29 September 2008

Dendritic cells infected with a vaccinia virus interleukin-2 vector secrete high levels of IL-2 and can become efficient antigen presenting cells that secrete high levels of the immunostimulatory cytokine IL-12.

scientific article published in August 2003

Detection of malignant mesothelioma in asbestos-exposed individuals: the potential role of soluble mesothelin-related protein

scientific article

Discovery of new biomarkers for malignant mesothelioma

scientific article

Does CA125 binding to mesothelin impact the detection of malignant mesothelioma?

scientific article published on 26 January 2013

Dual control of antitumor CD8 T cells through the programmed death-1/programmed death-ligand 1 pathway and immunosuppressive CD4 T cells: regulation and counterregulation.

scientific article

ENOX2-based early detection (ONCOblot) of asbestos-induced malignant mesothelioma 4-10 years in advance of clinical symptoms

scientific article

ERK1/2 and p38 MAP kinase control MMP-2, MT1-MMP, and TIMP action and affect cell migration: a comparison between mesothelioma and mesothelial cells

scientific article published on May 2006

Effect of NSAIDS and COX-2 inhibitors on the incidence and severity of asbestos-induced malignant mesothelioma: evidence from an animal model and a human cohort

scientific article

Erratum to: ENOX2-based early detection (ONCOblot) of asbestos-induced malignant mesothelioma 4-10 years in advance of clinical symptoms

scientific article published on 22 February 2016

Factors affecting soluble mesothelin related protein levels in an asbestos-exposed population

scientific article published in June 2010

Functional endogenous cytotoxic T lymphocytes are generated to multiple antigens co-expressed by progressing tumors; after intra-tumoral IL-2 therapy these effector cells eradicate established tumors

scientific article published on 11 November 2005

Gemcitabine exerts a selective effect on the humoral immune response: implications for combination chemo-immunotherapy

scientific article

Gene therapy of mesothelioma

scientific article

Genetic variants associated with increased risk of malignant pleural mesothelioma: a genome-wide association study.

scientific article

IL-2 intratumoral immunotherapy enhances CD8+ T cells that mediate destruction of tumor cells and tumor-associated vasculature: a novel mechanism for IL-2.

scientific article published on November 2003

IL-2/CD40-driven NK cells install and maintain potency in the anti-mesothelioma effector/memory phase

scientific article

Identification of a CD8+ T-cell response to a predicted neoantigen in malignant mesothelioma

scientific article published on 03 November 2019

Immune response profiling of malignant pleural mesothelioma for diagnostic and prognostic biomarkers

scientific article published on 24 March 2016

Immunotherapeutic Approaches and Vaccination Strategies

article

Immunotherapy and chemotherapy--a practical partnership

scientific article published on 01 May 2005

Immunotherapy for Lung Malignancies: From Gene Sequencing to Novel Therapies

scientific article

Immunotherapy for lung cancer

scientific article

Increased circulating miR-625-3p: a potential biomarker for patients with malignant pleural mesothelioma.

scientific article

Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cells

scientific article published in May 2003

Intratumoral poly-N-acetyl glucosamine-based polymer matrix provokes a prolonged local inflammatory response that, when combined with IL-2, induces regression of malignant mesothelioma in a murine model.

scientific article published on July 2005

Locally administered TLR7 agonists drive systemic antitumor immune responses that are enhanced by anti-CD40 immunotherapy

scientific article

Loss of antigen cross-presentation after complete tumor resection is associated with the generation of protective tumor-specific CD8(+) T-cell immunity

scientific article published in October 2012

Malignant cells from pleural fluids in malignant mesothelioma patients reveal novel mutations.

scientific article published on 9 March 2018

Malignant mesothelioma

scientific article published on 01 July 2005

Malignant mesothelioma biomarkers - from discovery to use in clinical practise for diagnosis, monitoring, screening and treatment

scientific article

Mesothelin and kidney function--analysis of relationship and implications for mesothelioma screening

scientific article published on 18 February 2011

Mesothelin-family proteins and diagnosis of mesothelioma

scientific article published in The Lancet

Mesothelin-related predictive and prognostic factors in malignant mesothelioma: a nested case-control study

scientific article

Neoadjuvant anti-tumor vaccination prior to surgery enhances survival

scientific article

New approaches for mesothelioma: biologics, vaccines, gene therapy, and other novel agents

scientific article

Partial, but not complete, tumor-debulking surgery promotes protective antitumor memory when combined with chemotherapy and adjuvant immunotherapy.

scientific article published on September 2005

Plasma versus serum levels of osteopontin and mesothelin in patients with malignant mesothelioma--which is best?

scientific article published on 12 March 2011

Pleural effusion hyaluronic acid as a prognostic marker in pleural malignant mesothelioma

scientific article published on 9 October 2013

Pre-treatment tumor neo-antigen responses in draining lymph nodes are infrequent but predict checkpoint blockade therapy outcome

scientific article published on 07 November 2019

Scientific Advances and New Frontiers in Mesothelioma Therapeutics

scientific article published on 01 September 2018

Scientists appeal to Quebec Premier Charest to stop exporting asbestos to the developing world.

scientific article published in April 2010

Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.

scientific article published on 08 September 2016

Sensitivity of urinary mesothelin in patients with malignant mesothelioma

scientific article published on September 2010

Serial immunomonitoring of cancer patients receiving combined antagonistic anti-CD40 and chemotherapy reveals consistent and cyclical modulation of T cell and dendritic cell parameters.

scientific article

Serum and pleural fluid biomarkers for mesothelioma

scientific article published on July 2009

Serum mesothelin for diagnosing malignant pleural mesothelioma: an individual patient data meta-analysis

scientific article

Serum mesothelin for early detection of asbestos-induced cancer malignant mesothelioma

scientific article published on 22 July 2010

Serum soluble mesothelin concentrations in malignant pleural mesothelioma: relationship to tumor volume, clinical stage and changes in tumor burden.

scientific article published on 21 December 2010

Soluble mesothelin in effusions: a useful tool for the diagnosis of malignant mesothelioma

scientific article

Soluble mesothelin related protein in mesothelioma

scientific article published on 01 February 2006

Soluble mesothelin-related protein--a blood test for mesothelioma

scientific article

Statins do not alter the incidence of mesothelioma in asbestos exposed mice or humans

scientific article

Strong spontaneous tumor neoantigen responses induced by a natural human carcinogen

scientific article published on 11 May 2015

Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity

scientific article

Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors

scientific article published in August 2003

Targeting the effector site with IFN-alphabeta-inducing TLR ligands reactivates tumor-resident CD8 T cell responses to eradicate established solid tumors

scientific article published on February 2008

The MARS feasibility trial: conclusions not supported by data

scientific article published in November 2011

The use of agonistic anti-CD40 therapy in treatments for cancer

scientific article published on August 2012

Tracking Neoantigens by Personalized Circulating Tumor DNA Sequencing during Checkpoint Blockade Immunotherapy in Non-Small Cell Lung Cancer

scientific article published on 26 March 2020

Tumor antigen cross-presentation and the dendritic cell: where it all begins?

scientific article

Tumor cells, rather than dendritic cells, deliver antigen to the lymph node for cross-presentation

scientific article

Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cells: a role for cycling TNFR2-expressing effector-suppressor T cells in limiting effective chemotherapy

scientific article published on 4 December 2008

Tumor-infiltrating dendritic cells exhibit defective cross-presentation of tumor antigens, but is reversed by chemotherapy.

scientific article published on 15 December 2014

Whole exome sequencing of an asbestos-induced wild-type murine model of malignant mesothelioma

scientific article

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