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List of works by Srikanth Givvimani

Angiotensin-II induced hypertension and renovascular remodelling in tissue inhibitor of metalloproteinase 2 knockout mice

scientific article

Anti-Parstatin Promotes Angiogenesis and Ameliorates Left Ventricular Dysfunction during Pressure Overload

scientific article published on March 2014

Attenuation of beta2-adrenergic receptors and homocysteine metabolic enzymes cause diabetic cardiomyopathy.

scientific article

Cardiac matrix: a clue for future therapy

scientific article

Cardiac specific deletion of N-methyl-d-aspartate receptor 1 ameliorates mtMMP-9 mediated autophagy/mitophagy in hyperhomocysteinemia

scientific article

Chronic hyperhomocysteinemia causes vascular remodelling by instigating vein phenotype in artery.

scientific article published on 13 August 2011

Cystathionine β-synthase and cystathionine γ-lyase double gene transfer ameliorate homocysteine-mediated mesangial inflammation through hydrogen sulfide generation

scientific article

Differential regulation of DNA methylation versus histone acetylation in cardiomyocytes during HHcy in vitro and in vivo: an epigenetic mechanism

scientific article

Dysregulation of Mfn2 and Drp-1 proteins in heart failure

scientific article

Epigenetic regulation of aortic remodeling in hyperhomocysteinemia.

scientific article

Exercise mitigates the adverse effects of hyperhomocysteinemia on macrophages, MMP-9, skeletal muscle, and white adipocytes

scientific article

Fibrinogen-induced increased pial venular permeability in mice

scientific article published on 12 October 2011

Folic acid mitigated cardiac dysfunction by normalizing the levels of tissue inhibitor of metalloproteinase and homocysteine-metabolizing enzymes postmyocardial infarction in mice

scientific article

H2S ameliorates oxidative and proteolytic stresses and protects the heart against adverse remodeling in chronic heart failure

scientific article

Homocysteine decreases blood flow to the brain due to vascular resistance in carotid artery.

scientific article published on 03 August 2008

Homocysteine elicits an M1 phenotype in murine macrophages through an EMMPRIN-mediated pathway

scientific article

Hydrogen sulfide ameliorates hyperhomocysteinemia-associated chronic renal failure

scientific article published on 27 May 2009

Hydrogen sulfide mitigates matrix metalloproteinase-9 activity and neurovascular permeability in hyperhomocysteinemic mice.

scientific article

Hydrogen sulfide mitigates transition from compensatory hypertrophy to heart failure

scientific article

Hyperhomocysteinemia Alters Sinoatrial and Atrioventricular Nodal Function: Role of Magnesium in Attenuating These Effects

Hyperhomocysteinemia and sudden cardiac death: potential arrhythmogenic mechanisms

scientific article published in January 2010

Hyperhomocysteinemia attenuates angiogenesis through reduction of HIF-1α and PGC-1α levels in muscle fibers during hindlimb ischemia

scientific article

Hyperhomocysteinemia: a missing link to dysfunctional HDL via paraoxanase-1.

scientific article

Increased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia

scientific article

MMP-2/TIMP-2/TIMP-4 versus MMP-9/TIMP-3 in transition from compensatory hypertrophy and angiogenesis to decompensatory heart failure.

scientific article

MMP-9 gene ablation mitigates hyperhomocystenemia-induced cognition and hearing dysfunction

scientific article

Matrix metalloproteinases in atherosclerosis: role of nitric oxide, hydrogen sulfide, homocysteine, and polymorphisms

scientific article

Mitochondrial division/mitophagy inhibitor (Mdivi) ameliorates pressure overload induced heart failure

scientific article

Moderate intensity exercise prevents diabetic cardiomyopathy associated contractile dysfunction through restoration of mitochondrial function and connexin 43 levels in db/db mice

scientific article published on 28 January 2016

Nutri-epigenetics ameliorates blood-brain barrier damage and neurodegeneration in hyperhomocysteinemia: role of folic acid

scientific article published on February 2014

Osteopontin-Stimulated Expression of Matrix Metalloproteinase-9 Causes Cardiomyopathy in the mdx Model of Duchenne Muscular Dystrophy

scientific article published on September 1, 2011

Synergism between arrhythmia and hyperhomo-cysteinemia in structural heart disease.

scientific article

Tetrahydrocurcumin ameliorates homocysteinylated cytochrome-c mediated autophagy in hyperhomocysteinemia mice after cerebral ischemia.

scientific article published on 3 January 2012