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List of works by Stephen L Abrams

Advances in targeting signal transduction pathways

scientific article

Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy

scientific article published on 21 February 2008

Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells

scientific article published on August 2011

Critical Roles of EGFR Family Members in Breast Cancer and Breast Cancer Stem Cells: Targets for Therapy

scientific article published on 4 March 2016

Diverse roles of GSK-3: tumor promoter-tumor suppressor, target in cancer therapy

scientific article published on 08 October 2013

Dominant roles of the Raf/MEK/ERK pathway in cell cycle progression, prevention of apoptosis and sensitivity to chemotherapeutic drugs

scientific article published on 15 April 2010

Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine

scientific article published on 16 November 2012

Effects of ectopic expression of NGAL on doxorubicin sensitivity

scientific article published on October 2012

Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy

scientific article published on 15 May 2010

Inhibition of GSK-3β activity can result in drug and hormonal resistance and alter sensitivity to targeted therapy in MCF-7 breast cancer cells

scientific article published on 09 January 2014

Involvement of Akt and mTOR in chemotherapeutic- and hormonal-based drug resistance and response to radiation in breast cancer cells

scientific article published on September 2011

Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy

scientific article published on July 2011

Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response

scientific article published on September 2012

Novel approaches to target cancer initiating cells-eliminating the root of the cancer

scientific article published on January 2012

Novel roles of androgen receptor, epidermal growth factor receptor, TP53, regulatory RNAs, NF-kappa-B, chromosomal translocations, neutrophil associated gelatinase, and matrix metalloproteinase-9 in prostate cancer and prostate cancer stem cells

scientific article

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance

scientific article

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health

scientific article published on March 2011

Roles of EGFR and KRAS and their downstream signaling pathways in pancreatic cancer and pancreatic cancer stem cells

scientific article published on 17 July 2015

Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

scientific article

Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy

scientific article published on 13 August 2015

Roles of signaling pathways in drug resistance, cancer initiating cells and cancer progression and metastasis

scientific article

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

scientific article

Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

scientific article

Signaling intermediates (MAPK and PI3K) as therapeutic targets in NSCLC.

scientific article published on January 2014

Targeting breast cancer initiating cells: advances in breast cancer research and therapy

scientific article

Targeting signal transduction pathways to eliminate chemotherapeutic drug resistance and cancer stem cells.

scientific article

Targeting the cancer initiating cell: the ultimate target for cancer therapy.

scientific article published on January 2012

The Raf/MEK/ERK pathway can govern drug resistance, apoptosis and sensitivity to targeted therapy

scientific article published on 10 May 2010

The therapeutic potential of mTOR inhibitors in breast cancer

scientific article published on 5 April 2016

Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways.

scientific article

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