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List of works by Niels Høiby

A cohort study of the Copenhagen CF Centre eradication strategy against Staphylococcus aureus in patients with CF ⬇️

scientific article published on July 10, 2012

A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and algT/U activity results in the loss of alginate production

scientific article

A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia.

scientific article published on September 2015

A mariner transposon vector adapted for mutagenesis in oral streptococci

scientific article

A non-fatal case of invasive zygomycete (Lichtheimia corymbifera) infection in an allogeneic haematopoietic cell transplant recipient

scientific article published on 23 November 2012

A personal history of research on microbial biofilms and biofilm infections

scientific article published on April 2014

A short history of microbial biofilms and biofilm infections

scientific article published on April 2017

Activation of pulmonary and lymph node dendritic cells during chronic Pseudomonas aeruginosa lung infection in mice

scientific article published on 24 March 2016

Adaptation of Pseudomonas aeruginosa to the chronic phenotype by mutations in the algTmucABD operon in isolates from Brazilian cystic fibrosis patients

scientific article published in PLoS ONE

Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

scientific article

Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis

scientific article published on 19 April 2019

Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing

scientific article

Alginate in Infection ⬇️

scientific article published on January 1, 1991

Alginate production affects Pseudomonas aeruginosa biofilm development and architecture, but is not essential for biofilm formation

scientific article

Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils

scientific article

Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model

scientific article published on 21 August 2015

Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils

scientific article

Antibiofilm Properties of Acetic Acid

scientific article published on July 2015

Antibiotic penetration and bacterial killing in a Pseudomonas aeruginosa biofilm model

scientific article published on 18 March 2015

Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system.

scientific article published on 30 March 2009

Antibiotic resistance of bacterial biofilms

scientific article published on 10 February 2010

Antibodies against Pseudomonas aeruginosa chromosomal beta-lactamase inpatients with cystic fibrosis are markers of the development of resistance of P. aeruginosa to beta-lactams

article

Antibodies against beta-lactamase can improve ceftazidime treatment of lung infection with beta-lactam-resistant Pseudomonas aeruginosa in a rat model of chronic lung infection.

scientific article published in December 2002

Antibody response against Mycobacterium avium complex in cystic fibrosis patients measured by a novel IgG ELISA test

scientific article published on 29 November 2018

Antibody response to Pseudomonas aeruginosa in cystic fibrosis patients: a marker of therapeutic success?--A 30-year cohort study of survival in Danish CF patients after onset of chronic P. aeruginosa lung infection

scientific article published on May 2004

Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Isolated From Cystic Fibrosis Patients

scientific article published on 20 February 2019

Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients

scientific article

Applying insights from biofilm biology to drug development - can a new approach be developed?

scientific article published on October 2013

Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors

scientific article (publication date: August 2003)

Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa

scientific article published on 8 October 2009

Autofluorescence in samples obtained from chronic biofilm infections--"all that glitters is not gold".

scientific article published on 5 February 2015

Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P. aeruginosa lung infection in Cftr(-/-) mice

scientific article

Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data

scientific article

Bacterial biofilm formation and treatment in soft tissue fillers.

scientific article

Bacterial evolution in PCD and CF patients follows the same mutational steps

scientific article

Bactericidal effect of colistin on planktonic Pseudomonas aeruginosa is independent of hydroxyl radical formation

scientific article published on 15 November 2013

Biofilms and host response - helpful or harmful

scientific article published on April 2017

Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

scientific article

Biofilms of Mycobacterium abscessus Complex Can Be Sensitized to Antibiotics by Disaggregation and Oxygenation

scientific article published on 27 January 2020

Biological Trojan horse: Antigen 43 provides specific bacterial uptake and survival in human neutrophils

scientific article

Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study

scientific article published on 12 July 2018

Cefotaximases (CTX-M-ases), an expanding family of extended-spectrum beta-lactamases

scientific article published on March 2004

Cellular responses of A549 alveolar epithelial cells to serially collected Pseudomonas aeruginosa from cystic fibrosis patients at different stages of pulmonary infection

scientific article

Characterization of paired mucoid/non-mucoid Pseudomonas aeruginosa isolates from Danish cystic fibrosis patients: antibiotic resistance, beta-lactamase activity and RiboPrinting.

scientific article

Cholera in Denmark--an imported case of illness

scientific article published on April 17, 1995

Chromosomal mechanisms of aminoglycoside resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients

scientific article published on 22 December 2008

Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines-implications for delayed wound closure?

scientific article published on 22 June 2017

Chronic Pseudomonas aeruginosa infection definition: EuroCareCF Working Group report.

scientific article published on June 2011

Chronic Pseudomonas aeruginosa lung infection in normal and athymic rats.

scientific article published in March 1993

Chronic Pseudomonas aeruginosa lung infection is more severe in Th2 responding BALB/c mice compared to Th1 responding C3H/HeN mice

scientific article published on November 1, 1997

Chronic infection with Achromobacter xylosoxidans in cystic fibrosis patients; a retrospective case control study

scientific article published on 13 June 2006

Chronic pulmonary disease with Mycobacterium abscessus complex is a biofilm infection.

scientific article

Chronic pulmonary infection with Stenotrophomonas maltophilia and lung function in patients with cystic fibrosis

scientific article published on 03 April 2011

Chronic urinary tract infections in patients with spinal cord lesions - biofilm infection with need for long-term antibiotic treatment

scientific article published on April 2017

Class A carbapenemases

scientific article published on 26 June 2007

Clearance of Pseudomonas aeruginosa foreign-body biofilm infections through reduction of the cyclic Di-GMP level in the bacteria

scientific article published on 20 May 2013

Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa

scientific article

Colonisation and infection of the paranasal sinuses in cystic fibrosis patients is accompanied by a reduced PMN response.

scientific article published on 15 May 2012

Combating biofilms

scientific article published on July 2012

Combination of microscopic techniques reveals a comprehensive visual impression of biofilm structure and composition

scientific article

Comparative genomic analysis of rapid evolution of an extreme-drug-resistant Acinetobacter baumannii clone

scientific article published on January 2013

Comparing the harmful effects of nontuberculous mycobacteria and Gram negative bacteria on lung function in patients with cystic fibrosis

scientific article published on 05 October 2015

Comparison of histological lesions in mink with acute hemorrhagic pneumonia associated with Pseudomonas aeruginosa or Escherichia coli

scientific article published on July 2013

Complement activation by Pseudomonas aeruginosa biofilms

scientific article published on 01 November 1993

Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes

scientific article published in 2013

Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD

scientific article published on November 2002

Culture-dependent and -independent investigations of microbial diversity on urinary catheters

scientific article

Current understanding of multi-species biofilms

scientific article

Cytokine and surface receptor diversity of NK cells in resistant C3H/HeN and susceptible BALB/c mice with chronic Pseudomonas aeruginosa lung infection

scientific article published on 01 September 2003

Decreased mucosal oxygen tension in the maxillary sinuses in patients with cystic fibrosis

scientific article published on 03 January 2011

Denitrification by cystic fibrosis pathogens - Stenotrophomonas maltophilia is dormant in sputum

scientific article

Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa.

scientific article

Detection of microbial diversity in endocarditis using cultivation-independent molecular techniques

scientific article

Development of antibiotic resistance and up-regulation of the antimutator gene pfpI in mutator Pseudomonas aeruginosa due to inactivation of two DNA oxidative repair genes (mutY, mutM).

scientific article

Diagnosis of biofilm infections in cystic fibrosis patients

scientific article published on April 2017

Diagnostic significance of measurements of specific IgG antibodies to Pseudomonas aeruginosa by three different serological methods.

scientific article

Dietzia papillomatosis bacteremia

scientific article

Differences in prevalence and treatment of Pseudomonas aeruginosa in cystic fibrosis centres in Denmark, Norway and Sweden.

scientific article published on 20 January 2009

Diffusion Retardation by Binding of Tobramycin in an Alginate Biofilm Model

scientific article

Direct sequencing and RipSeq interpretation as a tool for identification of polymicrobial infections

scientific article published on 30 January 2013

Distribution, organization, and ecology of bacteria in chronic wounds

scientific article published on 28 May 2008

Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection

scientific article

Draft Genome Sequences of Pseudomonas aeruginosa B3 Strains Isolated from a Cystic Fibrosis Patient Undergoing Antibiotic Chemotherapy

scientific article published on 17 October 2013

Dynamics and spatial distribution of beta-lactamase expression in Pseudomonas aeruginosa biofilms

scientific article published on April 2004

ESCMID guideline for the diagnosis and treatment of biofilm infections 2014.

scientific article published on 14 January 2015

Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts

scientific article published on 7 April 2010

Early immune response in susceptible and resistant mice strains with chronic Pseudomonas aeruginosa lung infection determines the type of T-helper cell response

article

Editorial comment

scientific article published on 01 May 2019

Effect of infectious dose and season on development of hemorrhagic pneumonia in mink caused by Pseudomonas aeruginosa

scientific article published on July 2013

Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa

scientific article published on 21 July 2008

Effects of ginseng onPseudomonas aeruginosamotility and biofilm formation

scientific article published on 07 March 2011

Effects of intratracheal administration of novispirin G10 on a rat model of mucoid Pseudomonas aeruginosa lung infection

scientific article published in September 2005

Effects of photoactivated titanium dioxide nanopowders and coating on planktonic and biofilm growth of Pseudomonas aeruginosa.

scientific article published on 25 August 2011

Effects of radix ginseng on microbial infections: a narrative review.

scientific article published on April 2014

Environmental heterogeneity drives within-host diversification and evolution of Pseudomonas aeruginosa

scientific article

Eosinophil cationic protein in sputum from cystic fibrosis patients with Pseudomonas aeruginosa infections

scientific article published in The Lancet

Epidemic spread of Pandoraea apista, a new pathogen causing severe lung disease in cystic fibrosis patients

scientific article

Epidemiology of Pseudomonas aeruginosa in cystic fibrosis and the possible role of contamination by dental equipment

scientific article published on 01 June 1997

Epidemiology of nontuberculous mycobacteria among patients with cystic fibrosis in Scandinavia

scientific article

Evaluation of a bovine antibody test for diagnosing Mycobacterium avium complex in patients with cystic fibrosis

scientific article published on 20 September 2016

Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

scientific article

Evolution of Antibiotic Resistance in Biofilm and Planktonic Pseudomonas aeruginosa Populations Exposed to Subinhibitory Levels of Ciprofloxacin

scientific article published on 27 July 2018

Evolutionary dynamics of bacteria in a human host environment

scientific article

Excretion of ciprofloxacin in sweat and multiresistant Staphylococcus epidermidis

scientific article published in The Lancet

Experimental Pseudomonas aeruginosa mediated rhino sinusitis in mink.

scientific article published on 27 December 2016

Experimental chronic Pseudomonas aeruginosa lung infection in rats. Non-specific stimulation with LPS reduces lethality as efficiently as specific immunization

scientific article published on May 1, 1995

Extensive Endoscopic Image-Guided Sinus Surgery Decreases BPI-ANCA in Patients with Cystic Fibrosis

scientific article published on 01 December 2012

Extracellular DNA and F-actin as targets in antibiofilm cystic fibrosis therapy

scientific article

Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms

scientific article

Extracellular lipase of Pseudomonas aeruginosa: biochemical characterization and effect on human neutrophil and monocyte function in vitro.

scientific article published in March 1991

Faster activation of polymorphonuclear neutrophils in resistant mice during early innate response to Pseudomonas aeruginosa lung infection

article

Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa

scientific article published on 27 January 2012

Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth

scientific article published on 05 January 2019

Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilms

scientific article published on 10 February 2014

Further Commentary

scientific article published on 09 September 2019

Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections

scientific article

Genetic adaptation of Pseudomonas aeruginosa during chronic lung infection of patients with cystic fibrosis: strong and weak mutators with heterogeneous genetic backgrounds emerge in mucA and/or lasR mutants

scientific article published on 17 December 2009

Genome Sequence of Pseudomonas aeruginosa Strain DK1-NH57388A, a Stable Mucoid Cystic Fibrosis Isolate

scientific article published on 25 February 2016

Heterogeneity of biofilms formed by nonmucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosis

scientific article published on October 2005

High β-lactamase levels change the pharmacodynamics of β-lactam antibiotics in Pseudomonas aeruginosa biofilms

scientific article published on 22 October 2012

Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin

scientific article

Hyperbaric oxygen therapy augments tobramycin efficacy in experimental Staphylococcus aureus endocarditis

scientific article published on 29 June 2017

Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients

scientific article published on 31 January 2019

Identification of outer membrane Porin D as a vitronectin-binding factor in cystic fibrosis clinical isolates of Pseudomonas aeruginosa

scientific article published on 2 June 2015

Identity and effects of quorum-sensing inhibitors produced by Penicillium species.

scientific article

IgG avidity to Pseudomonas aeruginosa over the course of chronic lung biofilm infection in cystic fibrosis.

scientific article published on 11 October 2017

Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds

scientific article published on 26 June 2017

Immunization with Pseudomonas aeruginosa vaccines and adjuvant can modulate the type of inflammatory response subsequent to infection.

scientific article

Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model

article

In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections

scientific article published on 21 December 2007

In vivo pharmacokinetics/pharmacodynamics of colistin and imipenem in Pseudomonas aeruginosa biofilm infection

scientific article

Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes

scientific article

Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions

scientific article published on 12 October 2015

Increased serum concentration of G-CSF in cystic fibrosis patients with chronic Pseudomonas aeruginosa pneumonia

scientific article published on 28 February 2006

Individual pharmacokinetic variation leads to underdosing of ciprofloxacin in some cystic fibrosis patients

scientific article published on 4 November 2016

Inflammation in Achromobacter xylosoxidans infected cystic fibrosis patients

article

Influence of antidrug antibodies on plectasin efficacy and pharmacokinetics

scientific article published on 17 August 2009

Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound.

scientific article published in January 2002

Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo

scientific article

Interference of Pseudomonas aeruginosa signalling and biofilm formation for infection control

scientific article published on 07 April 2010

Interferon-gamma (IFN-gamma) treatment decreases the inflammatory response in chronic Pseudomonas aeruginosa pneumonia in rats

article

Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin

scientific article published on 9 June 2010

Investigation of the algT operon sequence in mucoid and non-mucoid Pseudomonas aeruginosa isolates from 115 Scandinavian patients with cystic fibrosis and in 88 in vitro non-mucoid revertants

scientific article published in January 2008

Investigation of the presence of human or bovine respiratory syncytial virus in the lungs of mink (Neovison vison) with hemorrhagic pneumonia due to Pseudomonas aeruginosa

scientific article

Lack of the Major Multifunctional Catalase KatA in Pseudomonas aeruginosa Accelerates Evolution of Antibiotic Resistance in Ciprofloxacin-Treated Biofilms

scientific article published on 23 September 2019

Lipocalin 2 is protective against E. coli pneumonia

scientific article

Long-term azitromycin treatment of cystic fibrosis patients with chronic Pseudomonas aeruginosa infection; an observational cohort study

scientific article

Long-term, low-dose azithromycin treatment reduces the incidence but increases macrolide resistance in Staphylococcus aureus in Danish CF patients.

scientific article

Low efficacy of tobramycin in experimental Staphylococcus aureus endocarditis.

scientific article published on 6 October 2015

Mechanism of action of antibiotics in chronic pulmonary pseudomonas infection.

scientific article published on January 1994

Meropenem in cystic fibrosis patients infected with resistant Pseudomonas aeruginosa or Burkholderia cepacia and with hypersensitivity to beta-lactam antibiotics

scientific article published on January 1996

Methods to classify bacterial pathogens in cystic fibrosis

scientific article

Microbial pathogenesis and biofilm development

scientific article published in January 2005

Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms.

scientific article

Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients

scientific article published on 29 January 2007

Molecular epidemiology of chronic Pseudomonas aeruginosa airway infections in cystic fibrosis

scientific article

Mouse Model of Burn Wound and Infection: Thermal (Hot Air) Lesion-Induced Immunosuppression

scientific article published on 19 June 2017

Mucoid Pseudomonas aeruginosa isolates maintain the biofilm formation capacity and the gene expression profiles during the chronic lung infection of CF patients

article

Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.

scientific article published in June 1999

Multiple roles of Pseudomonas aeruginosa TBCF10839 PilY1 in motility, transport and infection.

scientific article

Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa

scientific article published on 29 May 2012

New antimicrobials in the management of cystic fibrosis

scientific article

New technology markedly improves hand-hygiene performance among healthcare workers after restroom visits.

scientific article

Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

scientific article

Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis

scientific article published on February 2009

Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis

scientific article

OXA-type carbapenemases

scientific article

Occurrence of hypermutable Pseudomonas aeruginosa in cystic fibrosis patients is associated with the oxidative stress caused by chronic lung inflammation

scientific article published on June 2005

OligoG CF-5/20 Disruption of Mucoid Pseudomonas aeruginosa Biofilm in a Murine Lung Infection Model

scientific article published on February 2016

Optimization of colistin dosing regimen for cystic fibrosis patients with chronic Pseudomonas aeruginosa biofilm lung infections

scientific article published on 25 February 2019

Oropharyngeal Candidiasis in Palliative Care Patients in Denmark

scientific article

P. aeruginosa flow-cell biofilms are enhanced by repeated phage treatments but can be eradicated by phage-ciprofloxacin combination

scientific article published on 01 March 2019

PNA-based fluorescence in situ hybridization for identification of bacteria in clinical samples

scientific article published on January 2014

Panax ginseng has anti-infective activity against opportunistic pathogen Pseudomonas aeruginosa by inhibiting quorum sensing, a bacterial communication process critical for establishing infection

scientific article

Pathology and Biofilm Formation in a Porcine Model of Staphylococcal Osteomyelitis

article

Pattern differentiation in co-culture biofilms formed by Staphylococcus aureus and Pseudomonas aeruginosa

scientific article

Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis.

scientific article published on 10 September 2013

Pharmacokinetics and Pharmacodynamics of Antibiotics in Biofilm Infections of Pseudomonas aeruginosa In Vitro and In Vivo

scientific article published on 01 January 2014

Pharmacokinetics/pharmacodynamics of colistin and imipenem on mucoid and nonmucoid Pseudomonas aeruginosa biofilms

scientific article

Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm

scientific article

Phenotypes selected during chronic lung infection in cystic fibrosis patients: implications for the treatment of Pseudomonas aeruginosa biofilm infections

scientific article published on June 2012

Phenotypic shift in Pseudomonas aeruginosa populations from cystic fibrosis lungs after 2-week antipseudomonal treatment

scientific article published on 16 September 2016

PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients

scientific article published on 3 October 2011

Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum

scientific article

Plasmid-borne AmpC beta-lactamases

scientific article

Plectasin shows intracellular activity against Staphylococcus aureus in human THP-1 monocytes and in a mouse peritonitis model

scientific article published on 08 September 2009

PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treated cystic fibrosis patients

scientific article published on 21 November 2011

Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

scientific article published on 21 October 2009

Polymorphonuclear leukocytes restrict growth of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients

scientific article

Polymyxin resistance of Pseudomonas aeruginosa phoQ mutants is dependent on additional two-component regulatory systems

scientific article published on 4 March 2013

Polysaccharides serve as scaffold of biofilms formed by mucoid Pseudomonas aeruginosa

scientific article published on 28 February 2012

Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in guinea pigs.

scientific article published on 15 November 2011

Preclinical in vitro and in vivo characterization of the fully human monoclonal IgM antibody KBPA101 specific for Pseudomonas aeruginosa serotype IATS-O11.

scientific article

Prehospital diagnostic and therapeutic management of otogenic Streptococcus pneumoniae meningitis

scientific article

Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs

scientific article published on 16 January 2020

Prosthesis infections after orthopedic joint replacement: the possible role of bacterial biofilms

scientific article published on 14 June 2013

Pseudomonas aeruginosa AmpR is a global transcriptional factor that regulates expression of AmpC and PoxB beta-lactamases, proteases, quorum sensing, and other virulence factors

scientific article published on November 2005

Pseudomonas aeruginosa alginate is refractory to Th1 immune response and impedes host immune clearance in a mouse model of acute lung infection.

scientific article published in September 2003

Pseudomonas aeruginosa biofilm aggravates skin inflammatory response in BALB/c mice in a novel chronic wound model

scientific article published on 25 February 2013

Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor

scientific article published on 27 November 2017

Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies.

scientific article

Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and beta-lactamase and alginate production.

scientific article published on April 2004

Pseudomonas aeruginosa biofilms in cystic fibrosis

scientific article

Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients.

scientific article published in June 2009

Pseudomonas aeruginosa mutations in lasI and rhlI quorum sensing systems result in milder chronic lung infection

scientific article published on 01 May 2001

Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes

scientific article published on 30 July 2009

Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent

scientific article published in February 2005

Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients

scientific article

Rapid identification of Stenotrophomonas maltophilia by peptide nucleic acid fluorescence in situ hybridization

scientific article published on 25 March 2014

Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa

scientific article

Recent advances in the treatment of Pseudomonas aeruginosainfections in cystic fibrosis ⬇️

scientific article published on April 4, 2011

Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment

scientific article

Relative contribution of Prevotella intermedia and Pseudomonas aeruginosa to lung pathology in airways of patients with cystic fibrosis

scientific article published on 29 September 2010

Respiratory bacterial infections in cystic fibrosis

scientific article published on May 2013

Respiratory syncytial virus infection facilitates acute colonization of Pseudomonas aeruginosa in mice.

scientific article published in December 2009

Restriction fragment length polymorphism of rRNA genes for molecular typing of members of the family Legionellaceae.

scientific article

Review of publication: Coping with Change

scientific article

S100A8/A9 is an important host defence mediator in neuropathic foot ulcers in patients with type 2 diabetes mellitus

scientific article published on 15 April 2016

Salmonella enterica serovar Typhi and S. Paratyphi A: need to expand the QRDR region?

scientific article published on 5 November 2010

Secretory IgA as a diagnostic tool for Pseudomonas aeruginosa respiratory colonization

scientific article published on 20 July 2012

Secretory IgA response against Pseudomonas aeruginosa in the upper airways and the link with chronic lung infection in cystic fibrosis

scientific article published on 22 June 2017

Secretory IgA-mediated immune response in saliva and early detection of Pseudomonas aeruginosa in the lower airways of pediatric cystic fibrosis patients

scientific article published on 31 January 2019

Sequence analysis of the Legionella micdadei groELS operon

scientific article published on January 1, 1991

Serodiagnosis of Mycobacterium abscessus complex infection in cystic fibrosis

scientific article published on 30 April 2015

Serological diagnosis of experimental Enterococcus faecalis endocarditis

scientific article published on 01 October 1998

Serum concentrations of GM-CSF and G-CSF correlate with the Th1/Th2 cytokine response in cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

article

Shifting paradigms of nontuberculous mycobacteria in cystic fibrosis

scientific article published on 11 April 2014

Silver against Pseudomonas aeruginosa biofilms

scientific article published on 01 August 2007

Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia

scientific article published on 5 November 2014

Sinus bacteriology in patients with cystic fibrosis or primary ciliary dyskinesia: A systematic review

scientific article published on September 2017

Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed?

scientific article published on 9 October 2014

Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia

scientific article

Some bacterial parameters influencing the neutrophil oxidative burst response to Pseudomonas aeruginosa biofilms

scientific article published on August 1, 1992

Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients

scientific article published on 20 March 2008

Staphylococcus aureus alters growth activity, autolysis, and antibiotic tolerance in a human host-adapted Pseudomonas aeruginosa lineage

scientific article published on 2 September 2014

Strategies for combating bacterial biofilm infections

scientific article

Sublethal ciprofloxacin treatment leads to rapid development of high-level ciprofloxacin resistance during long-term experimental evolution of Pseudomonas aeruginosa

scientific article published on 17 June 2013

Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model

scientific article published on 01 February 2012

Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors

scientific article published on July 2013

The LapG protein plays a role in Pseudomonas aeruginosa biofilm formation by controlling the presence of the CdrA adhesin on the cell surface ⬇️

scientific article

The clinical impact of bacterial biofilms

scientific article

The clonal antibody response to Pseudomonas aeruginosa heat shock protein is highly diverse in cystic fibrosis patients

article

The dlt genes play a role in antimicrobial tolerance of Streptococcus mutans biofilms

scientific article

The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection -- a pilot study

scientific article published on 23 October 2014

The implication of Pseudomonas aeruginosa biofilms in infections

scientific article published on April 2011

The importance of early diagnosis of Mycobacterium abscessus complex in patients with cystic fibrosis

scientific article published on 01 December 2018

The in vivo biofilm

scientific article published on 02 July 2013

The influence of allotypes on the IgG subclass response to chromosomal beta-lactamase of Pseudomonas aeruginosa in cystic fibrosis patients

article

The microorganisms in chronically infected end-stage and non-end-stage cystic fibrosis patients

scientific article

The phagocytic fitness of leucopatches may impact the healing of chronic wounds

scientific article published on 2 February 2016

The phenotypic evolution of Pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin.

scientific article

Thermal injury induces impaired function in polymorphonuclear neutrophil granulocytes and reduced control of burn wound infection

scientific article published on 11 December 2008

Towards diagnostic guidelines for biofilm-associated infections

scientific article

True microbiota involved in chronic lung infection of cystic fibrosis patients found by culturing and 16S rRNA gene analysis

scientific article

Typing of Pseudomonas aeruginosa from hemorrhagic pneumonia in mink (Neovison vison).

scientific article published on 11 December 2012

Understanding bacterial biofilms in patients with cystic fibrosis: current and innovative approaches to potential therapies

scientific article published in December 2002

Understanding biofilms — are we there yet?

scientific article published on 21 May 2012

Unusual distribution of Burkholderia cepacia complex species in Danish cystic fibrosis clinics may stem from restricted transmission between patients

scientific article published on 2 June 2010

Urine lipoarabinomannan point-of-care testing in patients affected by pulmonary nontuberculous mycobacteria--experiences from the Danish Cystic Fibrosis cohort study

scientific article

Use of carbapenems and other antibiotics for pulmonary infections in patients with cystic fibrosis.

scientific article published on August 1996

Use of cultivation-dependent and -independent techniques to assess contamination of central venous catheters: a pilot study

scientific article published on 28 October 2008

Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia in rats

scientific article published on 01 October 1995

Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia. A new prophylactic principle

scientific article published on February 1, 1997

Why chronic wounds will not heal: a novel hypothesis

scientific article published on January 2008

[Augmented renal clearance of antibiotics may lead to inadequate dosings for patients with sepsis]. ⬇️

scientific article

[Foreign body infections--biofilms and quorum sensing]

scientific article published on 01 November 2007

[Molecular biology and medical bacteriology]

scientific article published on 01 May 1995

[New recommendations for antibiotic dosing in patients with renal insufficiency and in patients undergoing haemodialysis]

scientific article published on 01 February 2008

[The 2nd white coat revolution?].

scientific article

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