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List of works by Ana Cristina Lima Leite

2-(phenylthio)ethylidene derivatives as anti-Trypanosoma cruzi compounds: Structural design, synthesis and antiparasitic activity

scientific article published on 07 July 2019

2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: structural design, synthesis and pharmacological evaluation

scientific article published on 06 August 2014

A Novel High-Content Screening-Based Method for Anti- Drug Discovery Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

scientific article

Anti-liver cancer activity in vitro and in vivo induced by 2-pyridyl 2,3-thiazole derivatives.

scientific article

Antitumor and immunomodulatory activities of thiosemicarbazones and 1,3-Thiazoles in Jurkat and HT-29 cells

scientific article published on 6 June 2016

Approaches for the development of new anti-Trypanosoma cruzi agents.

scientific article published on March 2009

Aryl thiosemicarbazones: In vitro and immunomodulatory activities against L. amazonensis

scientific article published on 19 April 2017

Compound profiling and 3D-QSAR studies of hydrazone derivatives with activity against intracellular Trypanosoma cruzi.

scientific article

Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death

scientific article published on 3 February 2014

Cytotoxic and toxicological effects of phthalimide derivatives on tumor and normal murine cells.

scientific article

Design, synthesis and biological evaluation of 3-[4-(7-chloro-quinolin-4-yl)-piperazin-1-yl]-propionic acid hydrazones as antiprotozoal agents

scientific article published on 24 January 2014

Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents

scientific article

Design, synthesis and structure–activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities

scientific article published on 20 April 2015

Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death

scientific article published on 16 February 2017

Evaluation of the anti-Schistosoma mansoni activity of thiosemicarbazones and thiazoles

scientific article published on 28 October 2013

Gastroprotective and ulcer healing effects of essential oil of Hyptis martiusii Benth. (Lamiaceae).

scientific article published on 15 January 2014

Genotoxic activity of 3-[3-phenyl-1,2,4-oxadiazol-5-yl] propionic acid and its peptidyl derivatives determined by Ames and SOS response tests

scientific article published in December 2005

Halogen atoms in the modern medicinal chemistry: hints for the drug design.

scientific article

Improvement of in vivo anticancer and antiangiogenic potential of thalidomide derivatives

scientific article

In vitro and in vivo activities of multi-target phtalimido-thiazoles on Schistosomiasis mansoni

scientific article published on 10 February 2020

In vitro evaluation of cytotoxicity and leishmanicidal activity of phthalimido-thiazole derivatives

scientific article published on 3 May 2017

Isatin derivatives and their antiviral properties against arboviruses, a Review

scientific article

Multi-target compounds acting in cancer progression: Focus on thiosemicarbazone, thiazole and thiazolidinone analogues

scientific article published on 14 March 2019

New 1,3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi.

scientific article published on 24 May 2016

Phthalimido-thiazole as privileged scaffold: activity against immature and adult worms of Schistosoma mansoni

scientific article published on 07 May 2018

Phthalimido-thiazoles as building blocks and their effects on the growth and morphology of Trypanosoma cruzi

scientific article published on 11 January 2016

Privileged Structures in the design of Potential Drug Candidates for Neglected Diseases

scientific article published on 23 October 2017

Repeated-Doses Toxicity Study of the Essential Oil of Hyptis martiusii Benth. (Lamiaceae) in Swiss Mice.

scientific article published on 10 September 2013

Ruthenium complexes endowed with potent anti-Trypanosoma cruzi activity: Synthesis, biological characterization and structure-activity relationships.

scientific article

Structural Investigation of Anti-Trypanosoma cruzi 2-Iminothiazolidin-4-ones Allows the Identification of Agents with Efficacy in Infected Mice

scientific article published on 07 December 2012

Structural design, synthesis and pharmacological evaluation of thiazoles against Trypanosoma cruzi

scientific article published on 22 September 2017

Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity.

scientific article

Structural improvement of new thiazolidinones compounds with antinociceptive activity in experimental chemotherapy-induced painful neuropathy

scientific article published on 23 January 2017

Structure-activity relationships of mononuclear metal-thiosemicarbazone complexes endowed with potent antiplasmodial and antiamoebic activities.

scientific article published on 21 July 2010

Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents.

scientific article published on 29 September 2010

Study of acute oral toxicity of the thiazole derivative N-(1-methyl-2-methyl-pyridine)-N-(p-bromophenylthiazol-2-yl)-hydrazine in a Syrian hamster

scientific article published on 21 December 2020

Study of in vitro biological activity of thiazoles on Leishmania (Leishmania) infantum

scientific article published on 09 March 2020

Synthesis and antitumour evaluation of peptidyl-like derivatives containing the 1,3-benzodioxole system

scientific article published on 18 December 2006

Synthesis and structure-activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain.

scientific article

Synthesis of 4'-(2-ferrocenyl)-2,2':6'2''-terpyridine: characterization and antiprotozoal activity of Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes

scientific article published on 31 January 2014

Synthesis of aminoacyl thiaolidones as potential antitumour agents

scientific article published on 23 February 2006

Synthesis, Cruzain docking, and in vitro studies of aryl-4-oxothiazolylhydrazones against Trypanosoma cruzi

scientific article

Synthesis, anticancer activity and mechanism of action of new thiazole derivatives

scientific article published on 14 December 2017

Synthesis, antitumour and antimicrobial activities of new peptidyl derivatives containing the 1,3-benzodioxole system

scientific article published in December 2004

Synthesis, docking, and in vitro activity of thiosemicarbazones, aminoacyl-thiosemicarbazides and acyl-thiazolidones against Trypanosoma cruzi

scientific article published on 3 February 2006

Thiosemicarbazones and Phthalyl-Thiazoles compounds exert antiviral activity against yellow fever virus and Saint Louis encephalitis virus

scientific article published on 6 January 2017

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