List of works - Karen Heyninck

A novel type of deubiquitinating enzyme

scientific article (publication date: 20 June 2003)

A20 inhibits NF-kappaB activation by dual ubiquitin-editing functions

scientific article

Abin1

Abin2

Adenoviral gene transfer of ABIN-1 protects mice from TNF/galactosamine-induced acute liver failure and lethality

scientific article published in August 2005

Adenoviral gene transfer of the NF-kappa B inhibitory protein ABIN-1 decreases allergic airway inflammation in a murine asthma model

scientific article published on 18 February 2005

Dietary flavanols modulate the transcription of genes associated with cardiovascular pathology without changes in their DNA methylation state.

scientific article

Ectopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cells

scientific article

Epigenetic control of cardiovascular health by nutritional polyphenols involves multiple chromatin-modifying writer-reader-eraser proteins.

scientific article published on 25 August 2015

Hepatic tumor necrosis factor signaling and nuclear factor-kappaB: effects on liver homeostasis and beyond.

scientific article published on 12 April 2007

How the venom from the ectoparasitoid Wasp nasonia vitripennis exhibits anti-inflammatory properties on mammalian cell lines

scientific article

Identification of differentially methylated BRCA1 and CRISP2 DNA regions as blood surrogate markers for cardiovascular disease

scientific article

Immunomodulatory effects of 17-O-acetylacuminolide in RAW264.7 cells and HUVECs: involvement of MAPK and NF-κB pathways

scientific article published on 20 October 2014

Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation

scientific article

LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappaB activation

scientific article

Mechanisms of crosstalk between TNF-induced NF-kappaB and JNK activation in hepatocytes.

scientific article published on 24 August 2006

Molecular insight in the multifunctional activities of Withaferin A.

scientific article

Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

scholarly article by Behrouz Hassannia et al published 1 August 2018 in Journal of Clinical Investigation

Nuclear factor-kappa B plays a central role in tumour necrosis factor-mediated liver disease.

scientific article published on October 2003

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells

scientific article published on 03 February 2014

Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas.

scientific article published in January 2002

Structure-function analysis of the A20-binding inhibitor of NF-kappa B activation, ABIN-1

scientific journal article

T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

scientific article

TNFalpha- and IKKbeta-mediated TANK/I-TRAF phosphorylation: implications for interaction with NEMO/IKKgamma and NF-kappaB activation

scientific article

The role of serine- and metalloproteases in Nasonia vitripennis venom in cell death related processes towards a Spodoptera frugiperda Sf21 cell line

scientific article published on 15 May 2013

The serotonin 5-HT7 receptors: two decades of research

scientific article

The yeast three-hybrid system as a tool to study caspases

scientific article published in January 2004

Ubiquitin: tool and target for intracellular NF-kappaB inhibitors.

scientific article published on 18 September 2006

Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway

scientific article

Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKβ.

scientific article published on 23 August 2014

Yeast two-hybrid screening for proteins interacting with the anti-apoptotic protein A20.

scientific article published in January 2004

List of works by Karen Heyninck

A novel type of deubiquitinating enzyme

A20 inhibits NF-kappaB activation by dual ubiquitin-editing functions

Abin1

Abin2

Adenoviral gene transfer of ABIN-1 protects mice from TNF/galactosamine-induced acute liver failure and lethality

Adenoviral gene transfer of the NF-kappa B inhibitory protein ABIN-1 decreases allergic airway inflammation in a murine asthma model

Dietary flavanols modulate the transcription of genes associated with cardiovascular pathology without changes in their DNA methylation state.

Ectopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cells

Epigenetic control of cardiovascular health by nutritional polyphenols involves multiple chromatin-modifying writer-reader-eraser proteins.

Hepatic tumor necrosis factor signaling and nuclear factor-kappaB: effects on liver homeostasis and beyond.

How the venom from the ectoparasitoid Wasp nasonia vitripennis exhibits anti-inflammatory properties on mammalian cell lines

Identification of differentially methylated BRCA1 and CRISP2 DNA regions as blood surrogate markers for cardiovascular disease

Immunomodulatory effects of 17-O-acetylacuminolide in RAW264.7 cells and HUVECs: involvement of MAPK and NF-κB pathways

Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation

LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappaB activation

Mechanisms of crosstalk between TNF-induced NF-kappaB and JNK activation in hepatocytes.

Molecular insight in the multifunctional activities of Withaferin A.

Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

Nuclear factor-kappa B plays a central role in tumour necrosis factor-mediated liver disease.

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells

Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas.

Structure-function analysis of the A20-binding inhibitor of NF-kappa B activation, ABIN-1

T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

TNFalpha- and IKKbeta-mediated TANK/I-TRAF phosphorylation: implications for interaction with NEMO/IKKgamma and NF-kappaB activation

The role of serine- and metalloproteases in Nasonia vitripennis venom in cell death related processes towards a Spodoptera frugiperda Sf21 cell line

The serotonin 5-HT7 receptors: two decades of research

The yeast three-hybrid system as a tool to study caspases

Ubiquitin: tool and target for intracellular NF-kappaB inhibitors.

Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway

Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKβ.

Yeast two-hybrid screening for proteins interacting with the anti-apoptotic protein A20.