List of works - Justyna Piekielna-Ciesielska

Antinociceptive and antidepressant-like action of endomorphin-2 analogs with proline surrogates in position 2.

scientific article published on 9 July 2014

Antinociceptive potency of a fluorinated cyclopeptide Dmt-c[D-Lys-Phe-p-CF3-Phe-Asp]NH2.

scientific article published in December 2018

Biased Agonism as an Emerging Strategy in the Search for Better Opioid Analgesics

scientific article published on 01 January 2020

Correction for "Synthesis of Mixed Opioid Affinity Cyclic Endomorphin-2 Analogues with Fluorinated Phenylalanines".

scientific article published on 9 May 2016

Cyclic pentapeptide analogs based on endomorphin-2 structure: cyclization studies using liquid chromatography combined with on-line mass spectrometry and tandem mass spectrometry

scientific article published on 10 February 2014

Cyclic side-chain-linked opioid analogs utilizing cis- and trans-4-aminocyclohexyl-D-alanine

scientific article published in December 2014

Cyclization in opioid peptides

scientific article published on June 2013

Cyclopeptide Dmt-[D-Lys-p-CF3-Phe-Phe-Asp]NH2, a novel G protein-biased agonist of the mu opioid receptor

scientific article published on 28 November 2017

Design, Synthesis and Functional Analysis of Cyclic Opioid Peptides with Dmt-Tic Pharmacophore

scientific article published on 17 September 2020

Effect of 2′,6′-dimethyl-l-tyrosine (Dmt) on pharmacological activity of cyclic endomorphin-2 and morphiceptin analogs

scientific article published on 20 October 2011

Endomorphin-2 analogs containing modified tyrosines: Biological and theoretical investigation of the influence on conformation and pharmacological profile

scientific article published on 28 June 2019

In vitro and in vivo activity of opioid cyclopeptide with mu/delta agonist profile biased toward β-arrestin.

scientific article published on 20 April 2018

Novel glycosylated endomorphin-2 analog produces potent centrally-mediated antinociception in mice after peripheral administration

scientific article published on 30 October 2013

Pharmacological Characterization of µ-Opioid Receptor Agonists with Biased G Protein or β-Arrestin Signaling, and Computational Study of Conformational Changes during Receptor Activation

scientific article published on 22 December 2020

Pharmacological characterization of endomorphin-2-based cyclic pentapeptides with methylated phenylalanine residues.

scientific article published on 13 March 2014

Pharmacological profile and molecular modeling of cyclic opioid analogs incorporating various phenylalanine derivatives

scientific article published on 15 May 2020

Pharmacological properties of novel cyclic pentapeptides with µ-opioid receptor agonist activity

scientific article

Redoubling the ring size of an endomorphin-2 analog transforms a centrally acting mu-opioid receptor agonist into a pure peripheral analgesic

scientific article

Ring size in cyclic endomorphin-2 analogs modulates receptor binding affinity and selectivity.

scientific article published in June 2015

Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

scientific article published on 05 December 2019

Synthesis and activity of opioid peptidomimetics with β2- and β3-amino acids

scientific article published on 3 August 2017

Synthesis of mixed MOR/KOR efficacy cyclic opioid peptide analogs with antinociceptive activity after systemic administration

scientific article published on 12 December 2015

Synthesis of mixed opioid affinity cyclic endomorphin-2 analogues with fluorinated phenylalanines

scientific article published on 3 April 2015

Synthesis, receptor binding studies, optical spectroscopic and in silico structural characterization of morphiceptin analogs with cis-4-amino-L-proline residues.

scientific article published on 7 November 2017

The search for opioid analgesics with limited tolerance liability

scientific article published on 01 June 2020

List of works by Justyna Piekielna-Ciesielska