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List of works by Jean-Yves Springael

Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3.

scientific article published on 30 October 2002

Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers

scientific article published on 7 February 2006

Allosteric properties of G protein-coupled receptor oligomers

scientific article published on 27 June 2007

Allosteric transinhibition by specific antagonists in CCR2/CXCR4 heterodimers

scientific article published on 22 August 2007

Biased signaling at chemokine receptors

scientific article

Can BRET-based biosensors be used to characterize G-protein mediated signaling pathways of an insect GPCR, the Schistocerca gregaria CRF-related diuretic hormone receptor?

scientific article published on 05 May 2020

Chemerin Added to Endothelin-1 Promotes Rat Pulmonary Artery Smooth Muscle Cell Proliferation and Migration

scientific article published on 30 July 2020

Chemerin influences endothelin- and serotonin-induced pulmonary artery vasoconstriction in rats

scientific article published on 16 June 2019

Coexpression of CCR7 and CXCR4 During B Cell Development Controls CXCR4 Responsiveness and Bone Marrow Homing

scientific article published on 18 December 2019

Consequences of ChemR23 heteromerization with the chemokine receptors CXCR4 and CCR7.

scientific article

Dimerization of chemokine receptors and its functional consequences

scientific article

Evidence for negative binding cooperativity within CCR5-CCR2b heterodimers

scientific article published on 27 October 2004

Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

scientific article (publication date: 11 July 2003)

Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists.

scientific article published on 15 September 2009

Highly potent HIV inhibition: engineering a key anti-HIV structure from PSC-RANTES into MIP-1 beta/CCL4.

scientific article published on 4 January 2008

Human T-cell leukemia virus type-1 Tax oncoprotein regulates G-protein signaling

scientific article published on 21 September 2006

Identification of a Novel Regulatory Mechanism of Nutrient Transport Controlled by TORC1-Npr1-Amu1/Par32

scientific article (publication date: July 2015)

Identification of nonpeptide CCR5 receptor agonists by structure-based virtual screening

scientific article

Nitrogen-source regulation of yeast gamma-glutamyl transpeptidase synthesis involves the regulatory network including the GATA zinc-finger factors Gln3, Nil1/Gat1 and Gzf3.

scientific article published in April 2003

Partial Agonist and Biased Signaling Properties of the Synthetic Enantiomers J113863/UCB35625 at Chemokine Receptors CCR2 and CCR5.

scientific article

Pericardial Adipose Tissue Regulates Granulopoiesis, Fibrosis and Cardiac Function After Myocardial Infarction.

scientific article published on 22 November 2017

Signaling Properties of Chemerin Receptors CMKLR1, GPR1 and CCRL2.

scientific article

Significance of N-terminal proteolysis of CCL14a to activity on the chemokine receptors CCR1 and CCR5 and the human cytomegalovirus-encoded chemokine receptor US28.

scientific article

Stroma Cell-Derived Factor-1α Signaling Enhances Calcium Transients and Beating Frequency in Rat Neonatal Cardiomyocytes ⬇️

scientific article published on February 27, 2013

Synergy between coproduced CC and CXC chemokines in monocyte chemotaxis through receptor-mediated events.

scientific article

The activation mechanism of chemokine receptor CCR5 involves common structural changes but a different network of interhelical interactions relative to rhodopsin

scientific article published on 25 January 2007

The chemerin/ChemR23 system does not affect the pro-inflammatory response of mouse and human macrophages ex vivo.

scientific article

Yeast Npi3/Bro1 is involved in ubiquitin-dependent control of permease trafficking

scientific article

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