Search filters

List of works by Jimmy D. Dikeakos

A Highly Conserved Residue in HIV-1 Nef Alpha Helix 2 Modulates Protein Expression.

scientific article

A Hydrophobic Patch in a Charged α-Helix Is Sufficient to Target Proteins to Dense Core Secretory Granules

scientific article published in Journal of Biological Chemistry

An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I.

scientific article

Antagonistic Coevolution of MER Tyrosine Kinase Expression and Function

scientific article published on 23 March 2017

Bacterial Superantigens Expand and Activate, Rather than Delete or Incapacitate, Preexisting Antigen-Specific Memory CD8+ T Cells

scientific article published on 01 April 2019

Discordant rearrangement of primary and anamnestic CD8+ T cell responses to influenza A viral epitopes upon exposure to bacterial superantigens: Implications for prophylactic vaccination, heterosubtypic immunity and superinfections

scientific article published on 20 May 2020

Efferocytic Defects in Early Atherosclerosis Are Driven by GATA2 Overexpression in Macrophages

scientific article published on 23 October 2020

Functional analysis of the C-terminal region of human adenovirus E1A reveals a misidentified nuclear localization signal

scientific article published on 6 September 2014

Functional and Structural Mimicry of Cellular Protein Kinase A Anchoring Proteins by a Viral Oncoprotein

scientific article

Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease

scientific article

HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling.

scientific article published on 14 November 2016

HIV-1 Nef: a master manipulator of the membrane trafficking machinery mediating immune evasion

scientific article

HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4+ T Cells

scientific article published on 17 March 2020

HIV-I Nef inhibitors: a novel class of HIV-specific immune adjuvants in support of a cure

scientific article published on 12 September 2017

Identification of Novel Subcellular Localization and Trafficking of HIV-1 Nef Variants from Reference Strains G (F1.93.HH8793) and H (BE.93.VI997)

article

Identification of a SARS-CoV-2 host metalloproteinase-dependent entry pathway differentially used by SARS-CoV-2 and variants of concern Alpha, Delta, and Omicron

scientific article

Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy

scientific article

MIiSR: Molecular Interactions in Super-Resolution Imaging Enables the Analysis of Protein Interactions, Dynamics and Formation of Multi-protein Structures

scientific article (publication date: December 2015)

Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2

scientific article

Modulation of secretory granule-targeting efficiency by cis and trans compounding of sorting signals

scientific article

PACS-1 and adaptor protein-1 mediate ACTH trafficking to the regulated secretory pathway

scientific article published on 17 November 2018

PC1/3, PC2 and PC5/6A are targeted to dense core secretory granules by a common mechanism

scientific article

Pathogenic infection of Rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV-1 infections

scientific article

Sending proteins to dense core secretory granules: still a lot to sort out.

scientific article published on 16 April 2007

Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action

scientific article

Soluble CD93 is an apoptotic cell opsonin recognized by αx β2

scientific article published on 07 February 2019

Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53

scientific article published on 01 June 2006

The C-terminal region of the proprotein convertase 1/3 (PC1/3) exerts a bimodal regulation of the enzyme activity in vitro

scientific article

The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4+ T cells

scientific article published on 12 January 2018

The interaction between HIV-1 Nef and adaptor protein-2 reduces Nef-mediated CD4+ T cell apoptosis

scientific article

The multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest.

scientific article

Therapeutic control of leishmaniasis by inhibitors of the mammalian target of rapamycin

scientific article published on 22 August 2018

Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Protein-induced Lysosomal Translocation of Proapoptotic Effectors Is Mediated by Phosphofurin Acidic Cluster Sorting Protein-2 (PACS-2) ⬇️

scientific article published on May 29, 2012

Upregulation of BST-2 by Type I Interferons Reduces the Capacity of Vpu To Protect HIV-1-Infected Cells from NK Cell Responses

scientific article published on 18 June 2019

Viral bimolecular fluorescence complementation: a novel tool to study intracellular vesicular trafficking pathways

scientific article published on 27 April 2015

Visualizing Interactions Between HIV-1 Nef and Host Cellular Proteins Using Ground-State Depletion Microscopy

scientific article published on 18 May 2015

Where in the Cell Are You? Probing HIV-1 Host Interactions through Advanced Imaging Techniques

scientific article

Paulina is supported by:

About Paulina

Help