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List of works by Tobias Opthof

A New In Vitro Co-Culture Model Using Magnetic Force-Based Nanotechnology.

scientific article published on 12 February 2016

A Single Intracoronary Injection of Midkine Reduces Ischemia/Reperfusion Injury in Swine Hearts: A Novel Therapeutic Approach for Acute Coronary Syndrome ⬇️

scientific article published on June 23, 2011

A comment to the paper by Waltman et al., Scientometrics, 87, 467-481, 2011

scientific article

A mutation in the human cardiac sodium channel (E161K) contributes to sick sinus syndrome, conduction disease and Brugada syndrome in two families

scientific article published in April 2005

A rejoinder on energy versus impact indicators

scientific article published on 20 September 2011

Aldosterone modulates I(f) current through gene expression in cultured neonatal rat ventricular myocytes

scientific journal article

An activation-repolarization time metric to predict localized regions of high susceptibility to reentry

scientific article published on 9 April 2015

Axon guidance of sympathetic neurons to cardiomyocytes by glial cell line-derived neurotrophic factor (GDNF)

scientific article (publication date: 2013)

Bepridil facilitates early termination of spiral-wave reentry in two-dimensional cardiac muscle through an increase of intercellular electrical coupling

scientific article published on 09 December 2010

Beta-, not alpha-adrenergic stimulation enhances conduction velocity in cultures of neonatal cardiomyocytes

scientific article published on 01 June 2007

Cardiac activation-repolarization patterns and ion channel expression mapping in intact isolated normal human hearts.

scientific article published on 10 October 2016

Cardiac expression of skeletal muscle sodium channels increases longitudinal conduction velocity in the canine 1-week myocardial infarction.

scientific article published on 10 April 2010

Cav3.2 subunit underlies the functional T-type Ca2+ channel in murine hearts during the embryonic period

scientific article published on 26 February 2004

Caveats for the journal and field normalizations in the CWTS (“Leiden”) evaluations of research performance

Chronic inhibition of Na+/H+-exchanger attenuates cardiac hypertrophy and prevents cellular remodeling in heart failure

scientific article published on 01 January 2005

Citation analysis with medical subject Headings (MeSH) using the Web of Knowledge: A new routine

article

Cloning, sequence analysis and phylogeny of connexin43 isolated from American black bear heart

scientific article published on 01 October 2007

Comparative study of nifekalant versus amiodarone for shock-resistant ventricular fibrillation in out-of-hospital cardiopulmonary arrest patients

scientific article published in April 2010

Comparison of the Impact Factors of the Most-Cited Cardiovascular Journals

scientific article published on 06 June 2019

Connexin43 orthologues in vertebrates: phylogeny from fish to man.

scientific article

Counterpoint: M cells do not have a functional role in the ventricular myocardium of the intact heart.

scientific article published on 15 January 2011

Decreased vagal control over heart rate in rats with right-sided congestive heart failure: downregulation of neuronal nitric oxide synthase

scientific article published in April 2005

Developmental changes of Ca(2+) handling in mouse ventricular cells from early embryo to adulthood

scientific article published in August 2002

Dietary fish oil reduces the incidence of triggered arrhythmias in pig ventricular myocytes

scientific article published on 17 July 2007

Dietary n-3 fatty acids promote arrhythmias during acute regional myocardial ischemia in isolated pig hearts☆

scientific article published on 13 October 2006

Differences in citation frequency of clinical and basic science papers in cardiovascular research ⬇️

scientific article published on May 13, 2011

Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells

scientific article published on 12 May 2003

Discontinuous conduction in mouse bundle branches is caused by bundle-branch architecture

scientific article published on 03 October 2005

Dispersion in ventricular repolarization in the human, canine and porcine heart.

scientific article

Dispersion of repolarization and arrhythmogenesis

scientific article

Dispersion of repolarization in canine ventricle and the electrocardiographic T wave: Tp-e interval does not reflect transmural dispersion

scientific article published on 29 November 2006

Early repolarization in mice causes overestimation of ventricular activation time by the QRS duration

scientific article published on 20 September 2012

Early termination of spiral wave reentry by combined blockade of Na+ and L-type Ca2+ currents in a perfused two-dimensional epicardial layer of rabbit ventricular myocardium

scientific article published on 21 January 2009

Electrocardiographic T wave and its relation with ventricular repolarization along major anatomical axes

scientific article published on 16 May 2014

Electrotonic cancellation of transmural electrical gradients in the left ventricle in man.

scientific article

Embryological development of pacemaker hierarchy and membrane currents related to the function of the adult sinus node: implications for autonomic modulation of biopacemakers

scientific article published on 3 January 2007

Expression of the electrophysiological system during murine embryonic stem cell cardiac differentiation.

scientific article published in January 2003

Gender differences in the long QT syndrome: effects of beta-adrenoceptor blockade

scientific article published on 01 February 2002

Glial cell line-derived neurotrophic factor (GDNF) enhances sympathetic neurite growth in rat hearts at early developmental stages ⬇️

scientific article published on December 1, 2010

Heterogeneous expression of connexins in rabbit sinoatrial node cells: correlation between connexin isotype and cell size

scientific article published in January 2002

IK1 modulates the U-wave: insights in a 100-year-old enigma

scientific article published on 27 November 2008

Impact Factor of the Chinese Journal of Physiology in 2009: Meet the Readers

scientific article published on August 31, 2010

Impact factor of the Chinese Journal of Physiology in 2007: building a strong foundation

scientific article published on 01 August 2008

Impact factors: no totum pro parte by skewness of citation

scientific article published on 01 February 2004

In vivo dispersion in repolarization and arrhythmias in the human heart

scientific article published on 01 January 2006

Incorporated sarcolemmal fish oil fatty acids shorten pig ventricular action potentials

scientific article published on 28 February 2006

Increased Late Sodium Current Contributes to the Electrophysiological Effects of Chronic, but Not Acute, Dofetilide Administration.

scientific article published on April 2016

Inhibition of intercellular coupling stabilizes spiral-wave reentry, whereas enhancement of the coupling destabilizes the reentry in favor of early termination

scientific article published on 15 June 2012

Intercellular coupling through gap junctions masks M cells in the human heart

scientific article published on 01 May 2004

Interventricular dispersion in repolarization causes bifid T waves in dogs with dofetilide-induced long QT syndrome

scientific article published on 24 February 2015

Ionic mechanisms of acquired QT prolongation and torsades de pointes in rabbits with chronic complete atrioventricular block

scientific article published on 01 October 2002

Is there a significant transmural gradient in repolarization time in the intact heart?: Repolarization Gradients in the Intact Heart

scientific article published in February 2009

J-Waves in Epicardial Electrograms Can Guide Ablation of Arrhythmogenic Substrates

scientific article published on 01 January 2019

Larger cell size in rabbits with heart failure increases myocardial conduction velocity and QRS duration.

scientific article published on 6 February 2006

Left atrial pressure reduction for mitral stenosis reverses left atrial direction-dependent conduction abnormalities

scientific article published on 25 November 2009

Letter by Opthof et al regarding article, "Prolonged Tpeak to tend interval on the resting electrocardiogram is associated with increased risk of sudden cardiac death"

scientific article published on 01 December 2011

Local transmural action potential gradients are absent in the isolated, intact dog heart but present in the corresponding coronary-perfused wedge

scientific article

Long-term cardiac memory in canine heart is associated with the evolution of a transmural repolarization gradient

scientific article published on 28 February 2007

Mechanism of Ventricular Premature Beats Elicited by Left Stellate Ganglion Stimulation During Acute Ischemia of the Anterior Left Ventricle

scientific article published on 27 August 2020

Midkine gene transfer after myocardial infarction in rats prevents remodelling and ameliorates cardiac dysfunction.

scientific article

Molecular aspects of adrenergic modulation of cardiac L-type Ca2+ channels.

scientific article

Molecular aspects of adrenergic modulation of the transient outward current.

scientific article published on 27 April 2006

Monophasic action potentials and activation recovery intervals as measures of ventricular action potential duration: Experimental evidence to resolve some controversies

article

Normalization at the field level: Fractional counting of citations

P19 embryonal carcinoma cells: a suitable model system for cardiac electrophysiological differentiation at the molecular and functional level.

scientific article

Pathophysiological significance of T-type Ca2+ channels: expression of T-type Ca2+ channels in fetal and diseased heart

scientific article

Pharmacological blockade of IKs destabilizes spiral-wave reentry under β-adrenergic stimulation in favor of its early termination

scientific article published on 28 April 2012

Postrepolarization refractoriness in acute ischemia and after antiarrhythmic drug administration: action potential duration is not always an index of the refractory period.

scientific article published on 28 January 2012

Prediction of atrial fibrillation: Role of the atrial gradient

scientific article published on 01 April 2005

Pro- and antiarrhythmic properties of a diet rich in fish oil.

scientific article

Productivity in science: more more and more?

scientific article published on 01 November 2002

Quantification of sympathetic hyperinnervation and denervation after myocardial infarction by three-dimensional assessment of the cardiac sympathetic network in cleared transparent murine hearts

scientific article published on 28 July 2017

Rebuttal to M cells are present in the ventricular myocardium. Counterpoint

scientific article published on 01 July 2011

Reconstituted High-Density Lipoprotein Shortens Cardiac Repolarization

scientific article published on 01 June 2011

Remaining problems with the “New Crown Indicator” (MNCS) of the CWTS

Remodeling of gap junctions in mouse hearts hypertrophied by forced retinoic acid signaling

scientific article published in October 2002

Repolarization gradients in the canine left ventricle before and after induction of short-term cardiac memory

scientific article published on 12 September 2005

Repolarization gradients in the intact heart: transmural or apico-basal?

scientific article published on 15 March 2012

Scopus' SNIP indicator: Reply to Moed

Scopus's source normalized impact per paper (SNIP) versus a journal impact factor based on fractional counting of citations

article

Simulating T-wave parameters of local extracellular electrograms with a whole-heart bidomain reaction-diffusion model: Size matters!

scientific article published in January 2007

Slow conduction and enhanced anisotropy increase the propensity for ventricular tachyarrhythmias in adult mice with induced deletion of connexin43.

scientific article published on 16 February 2004

Sp1 and Sp3 activate the rat connexin40 proximal promoter

scientific article published on March 2002

Stellate ganglion stimulation causes spatiotemporal changes in ventricular repolarization in pig

scientific article published on 07 January 2020

Submissions, impact factor, reviewer's recommendations and geographical bias within the peer review system (1997-2002): focus on Germany.

scientific article

Subtype switching of L-Type Ca 2+ channel from Cav1.3 to Cav1.2 in embryonic murine ventricle

scientific article

Synchronization of repolarization by mechano-electrical coupling in the porcine heart

scientific article published on 01 May 2015

T-type Ca2+ channel blockers prevent cardiac cell hypertrophy through an inhibition of calcineurin-NFAT3 activation as well as L-type Ca2+ channel blockers

scientific article

The Association of Abnormal Ventricular Wall Motion and Increased Dispersion of Repolarization in Humans is Independent of the Presence of Myocardial Infarction ⬇️

scientific article published on July 3, 2012

The Brugada ECG pattern: a marker of channelopathy, structural heart disease, or neither? Toward a unifying mechanism of the Brugada syndrome.

scientific article published on June 2010

The effect of enhanced gap junctional conductance on ventricular conduction in explanted hearts from patients with heart failure

scientific article published on 12 January 2009

The electrocardiogram of vertebrates: Evolutionary changes from ectothermy to endothermy

article

The hidden secrets of the hibernator's heart may protect against arrhythmias

scientific article published on 01 September 2005

The hills and valleys of an impact factor

scientific article published on 01 August 2005

The patient U wave

scientific article

The positive T wave.

scientific article published in July 2007

The significance of the peer review process against the background of bias: priority ratings of reviewers and editors and the prediction of citation, the role of geographical bias

scientific article published in December 2002

There is no transmural heterogeneity in an index of action potential duration in the canine left ventricle

scientific article published on 20 March 2009

Transmural dispersion in LQT3 and arrhythmogenesis

scientific article published on 28 July 2005

Turning the tables on citation analysis one more time: Principles for comparing sets of documents

article

Validation of a simple model for the morphology of the T wave in unipolar electrograms

scientific article published on 22 May 2009

Ventricular repolarization: an overview of (patho)physiology, sympathetic effects and genetic aspects

scientific article

Why the Brugada syndrome is not yet a disease: syndromes, diseases, and genetic causality

scientific article published on 16 September 2006

beta3-Adrenoceptors in the heart

scientific article published in December 2002

hα: the scientist as chimpanzee or bonobo

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