List of works - Roberto Parrilla

A variant thrombasthenic phenotype associated with compound heterozygosity of integrin beta3-subunit: (Met124Val)beta3 alters the subunit dimerization rendering a decreased number of constitutive active alphaIIbbeta3 receptors.

scientific article published in December 2004

Agonist-induced aggregation of Chinese hamster ovary cells coexpressing the human receptors for fibrinogen (integrin alphaIIbbeta3) and the platelet-activating factor: dissociation between adhesion and aggregation.

scientific article published on April 2002

Cloning and functional characterization of the 5′ flanking region of the human mitochondrial malic enzyme gene

2001 scientific article

Control of cell adhesion and migration by podocalyxin. Implication of Rac1 and Cdc42.

scientific article published on 8 February 2013

Diminished thrombogenic responses by deletion of the Podocalyxin Gene in mouse megakaryocytes

scientific article

Disruption of the Cys5-Cys7 disulfide bridge in the platelet glycoprotein Ibbeta prevents the normal maturation and surface exposure of GPIb-IX complexes

scientific article published in September 2003

Disruption of the beta3 663-687 disulfide bridge confers constitutive activity to beta3 integrins

scientific article published on 19 June 2003

Expression of podocalyxin enhances the adherence, migration, and intercellular communication of cells

scientific article

Megakaryocyte gene targeting mediated by restricted expression of recombinase Cre.

scientific article published on 12 October 2010

Modification of kidney barrier function by the urokinase receptor

scientific article published on 16 December 2007

Nonsense mutation in exon-19 of GPIIb associated with thrombasthenic phenotype. Failure of GPIIb(delta597-1008) to form stable complexes with GPIIIa

scientific article published on 01 April 2002

Overexpression of podocalyxin in megakaryocytes and platelets decreases the bleeding time and enhances the agonist-induced aggregation of platelets.

scientific article published on 12 March 2010

Release of podocalyxin into the extracellular space. Role of metalloproteinases

scientific article published on 15 May 2011

Role of transcription factor Sp1 and CpG methylation on the regulation of the human podocalyxin gene promoter

scientific article

Variations in platelet protein associated with arterial thrombosis.

scientific article

Ventricular enlargement associated with the panneural ablation of the podocalyxin gene

scientific article published on 23 October 2009

alpha-Adrenergic-mediated activation of human reconstituted fibrinogen receptor (integrin alphaIIbbeta3) in Chinese hamster ovary cells.

scientific article published in December 2004

List of works by Roberto Parrilla

A variant thrombasthenic phenotype associated with compound heterozygosity of integrin beta3-subunit: (Met124Val)beta3 alters the subunit dimerization rendering a decreased number of constitutive active alphaIIbbeta3 receptors.

Agonist-induced aggregation of Chinese hamster ovary cells coexpressing the human receptors for fibrinogen (integrin alphaIIbbeta3) and the platelet-activating factor: dissociation between adhesion and aggregation.

Cloning and functional characterization of the 5′ flanking region of the human mitochondrial malic enzyme gene

Control of cell adhesion and migration by podocalyxin. Implication of Rac1 and Cdc42.

Diminished thrombogenic responses by deletion of the Podocalyxin Gene in mouse megakaryocytes

Disruption of the Cys5-Cys7 disulfide bridge in the platelet glycoprotein Ibbeta prevents the normal maturation and surface exposure of GPIb-IX complexes

Disruption of the beta3 663-687 disulfide bridge confers constitutive activity to beta3 integrins

Expression of podocalyxin enhances the adherence, migration, and intercellular communication of cells

Megakaryocyte gene targeting mediated by restricted expression of recombinase Cre.

Modification of kidney barrier function by the urokinase receptor

Nonsense mutation in exon-19 of GPIIb associated with thrombasthenic phenotype. Failure of GPIIb(delta597-1008) to form stable complexes with GPIIIa

Overexpression of podocalyxin in megakaryocytes and platelets decreases the bleeding time and enhances the agonist-induced aggregation of platelets.

Release of podocalyxin into the extracellular space. Role of metalloproteinases

Role of transcription factor Sp1 and CpG methylation on the regulation of the human podocalyxin gene promoter

Variations in platelet protein associated with arterial thrombosis.

Ventricular enlargement associated with the panneural ablation of the podocalyxin gene

alpha-Adrenergic-mediated activation of human reconstituted fibrinogen receptor (integrin alphaIIbbeta3) in Chinese hamster ovary cells.