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List of works by Maria-Ana Ghetie

An anti-CD19 antibody inhibits the interaction between P-glycoprotein (P-gp) and CD19, causes P-gp to translocate out of lipid rafts, and chemosensitizes a multidrug-resistant (MDR) lymphoma cell line

scientific article published on 4 March 2004

Anti-CD19 antibodies inhibit the function of the P-gp pump in multidrug-resistant B lymphoma cells.

scientific article published in December 1999

Anti-CD19 inhibits the growth of human B-cell tumor lines in vitro and of Daudi cells in SCID mice by inducing cell cycle arrest

scientific article published on March 1994

Antitumor activity of Fab' and IgG-anti-CD22 immunotoxins in disseminated human B lymphoma grown in mice with severe combined immunodeficiency disease: effect on tumor cells in extranodal sites

scientific article published on November 1991

Binding of cytophilic rabbit IgG to homologous hepatocytes ⬇️

scientific article published on June 15, 1979

Combination immunotoxin treatment and chemotherapy in SCID mice with advanced, disseminated Daudi lymphoma

scientific article published on 01 September 1996

Covalent binding of human alpha 2-macroglobulin to deglycosylated ricin A chain and its immunotoxins

scientific article

Disseminated or localized growth of a human B-cell tumor (Daudi) in SCID mice

scientific article published on March 1990

Effect of sublethal irradiation of SCID mice on growth of B-cell lymphoma xenografts and on efficacy of chemotherapy and/or immunotoxin therapy

scientific article published on 01 June 1996

Eradication of minimal disease in severe combined immunodeficient mice with disseminated Daudi lymphoma using chemotherapy and an immunotoxin cocktail.

scientific article published on August 1994

Evaluation of four CD22 antibodies as ricin A chain-containing immunotoxins for the in vivo therapy of human B-cell leukemias and lymphomas

scientific article

Evaluation of ricin A chain-containing immunotoxins directed against CD19 and CD22 antigens on normal and malignant human B-cells as potential reagents for in vivo therapy

scientific article published on 01 May 1988

Generation of multidrug resistant lymphoma cell lines stably expressing P-glycoprotein

scientific article

Genetic engineering of an immunotoxin to eliminate pulmonary vascular leak in mice

scientific article published on 10 March 2003

Homodimerization of tumor-reactive monoclonal antibodies markedly increases their ability to induce growth arrest or apoptosis of tumor cells

scientific article published on July 1997

Homodimers but not monomers of Rituxan (chimeric anti-CD20) induce apoptosis in human B-lymphoma cells and synergize with a chemotherapeutic agent and an immunotoxin.

scientific article

Immunotoxins for the Treatment of B-Cell Lymphomas ⬇️

scientific article published on July 1, 1997

Interaction between rabbit IgG immune complexes and Ricinus agglutinin

scientific article published on 01 March 1986

Isolation of a rabbit IgG fraction with cytophilic properties ⬇️

scientific article published on May 13, 1983

Large scale preparation of an immunoconjugate constructed with human recombinant CD4 and deglycosylated ricin A chain

scientific article published on January 1990

Large scale preparation of immunotoxins constructed with the Fab' fragment of IgG1 murine monoclonal antibodies and chemically deglycosylated ricin A chain

scientific article published in September 1988

Preparation and characterization of conjugates of recombinant CD4 and deglycosylated ricin A chain using different cross-linkers

scientific article published on January 1990

Protein A vectorized toxins--I. Preparation and properties of protein A-ricin toxin conjugates

scientific article published on 01 December 1986

Protein a vectorized toxins—II. Preparation and “in vitro” cytotoxic effect of protein A-ricin a chain conjugate on antibody coated human tumour cells ⬇️

scientific article published on 01 May 1988

Recent developments in immunotoxin therapy

scientific article published on October 1994

Ricin A-chain and ricin A-chain immunotoxins rapidly damage human endothelial cells: implications for vascular leak syndrome

scientific article

Rituximab but not other anti-CD20 antibodies reverses multidrug resistance in 2 B lymphoma cell lines, blocks the activity of P-glycoprotein (P-gp), and induces P-gp to translocate out of lipid rafts

scientific article published on September 2006

Targeting mammalian target of rapamycin to both downregulate and disable the P-glycoprotein pump in multidrug-resistant B-cell lymphoma cell lines

scientific article

Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity of a human breast cancer cell line in vitro and in vivo.

scientific article

The GLP large scale preparation of immunotoxins containing deglycosylated ricin A chain and a hindered disulfide bond

scientific article published in September 1991

The antitumor activity of an anti-CD22 immunotoxin in SCID mice with disseminated Daudi lymphoma is enhanced by either an anti-CD19 antibody or an anti-CD19 immunotoxin

scientific article published in November 1992

The combined use of an immunotoxin and a radioimmunoconjugate to treat disseminated human B-cell lymphoma in immunodeficient mice

scientific article published on 01 February 2000

The epitope specificity and tissue reactivity of four murine monoclonal anti-CD22 antibodies

scientific article published on 01 January 1989

The evaluation of recombinant, chimeric, tetravalent antihuman CD22 antibodies

scientific article published on February 2004

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