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List of works by Roderick A Capaldi

A functionally active human F1F0 ATPase can be purified by immunocapture from heart tissue and fibroblast cell lines. Subunit structure and activity studies

scientific article

A replicating module as the unit of mitochondrial structure and functioning

scientific article

An alternative strategy to determine the mitochondrial proteome using sucrose gradient fractionation and 1D PAGE on highly purified human heart mitochondria

scientific article

An immunocytochemical approach to detection of mitochondrial disorders

scientific article published on October 2002

Analysis of steady-state protein phosphorylation in mitochondria using a novel fluorescent phosphosensor dye.

scientific article

Cell cycle dependent morphology changes and associated mitochondrial DNA redistribution in mitochondria of human cell lines

scientific article published in May 2002

Characterization of dynamic and steady-state protein phosphorylation using a fluorescent phosphoprotein gel stain and mass spectrometry

scientific article published in August 2004

Characterization of the human heart mitochondrial proteome

scientific article

Detection of pyruvate dehydrogenase E1 alpha-subunit deficiencies in females by immunohistochemical demonstration of mosaicism in cultured fibroblasts

scientific article published on July 2002

Early developmental pathology due to cytochrome c oxidase deficiency is revealed by a new zebrafish model

scientific article published on 30 August 2007

Energy substrate modulates mitochondrial structure and oxidative capacity in cancer cells

scientific article

Focused proteomics: monoclonal antibody-based isolation of the oxidative phosphorylation machinery and detection of phosphoproteins using a fluorescent phosphoprotein gel stain

scientific article

Focused proteomics: towards a high throughput monoclonal antibody-based resolution of proteins for diagnosis of mitochondrial diseases

scientific article published in December 2004

Heterogeneous distribution of pyruvate dehydrogenase in the matrix of mitochondria

scientific article published in February 2002

Immunological approaches to the characterization and diagnosis of mitochondrial disease

scientific article published in September 2004

Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators

scientific article

Lateral-flow immunoassay for detecting drug-induced inhibition of mitochondrial DNA replication and mtDNA-encoded protein synthesis

scientific article

Lateral-flow immunoassay for the frataxin protein in Friedreich's ataxia patients and carriers

scientific article published on 15 May 2008

Mass spectrometric identification of a novel phosphorylation site in subunit NDUFA10 of bovine mitochondrial complex I

scientific article published on 01 April 2005

Mitochondrial impairment by PPAR agonists and statins identified via immunocaptured OXPHOS complex activities and respiration

scientific article published on 21 June 2007

Mitochondrial oxidative phosphorylation protein levels in peripheral blood mononuclear cells correlate with levels in subcutaneous adipose tissue within samples differing by HIV and lipoatrophy status

scientific article published on October 2008

Monitoring oxidative and nitrative modification of cellular proteins; a paradigm for identifying key disease related markers of oxidative stress

scientific article published on 04 July 2008

Novel antibody-based strategies for the rapid diagnosis of mitochondrial disease and dysfunction

scientific article published on 19 May 2009

Oxidative damage to mitochondrial complex I due to peroxynitrite: identification of reactive tyrosines by mass spectrometry

scientific article

Oxidative post-translational modification of tryptophan residues in cardiac mitochondrial proteins

scientific article

Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled.

scientific article

Proteomic analysis of succinate dehydrogenase and ubiquinol-cytochrome c reductase (Complex II and III) isolated by immunoprecipitation from bovine and mouse heart mitochondria

scientific journal article

Quantitative proteomics: the copy number of pyruvate dehydrogenase is more than 10(2)-fold lower than that of complex III in human mitochondria

scientific article (publication date: 9 October 2002)

Rapid analysis of mitochondrial DNA depletion by fluorescence in situ hybridization and immunocytochemistry: potential strategies for HIV therapeutic monitoring

scientific article published on August 2004

Rapid purification and mass spectrometric characterization of mitochondrial NADH dehydrogenase (Complex I) from rodent brain and a dopaminergic neuronal cell line.

scientific article

Relationships among molecular genetic and respiratory properties of Parkinson's disease cybrid cells show similarities to Parkinson's brain tissues

scientific article

Small-scale immunopurification of cytochrome c oxidase for a high-throughput multiplexing analysis of enzyme activity and amount

scientific article published on 01 December 2007

The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11

scientific article (publication date: 24 July 2007)

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

scientific article

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