List of works by Irvin M. Modlin

A 5-decade analysis of 13,715 carcinoid tumors

scientific article

A 50-year analysis of 562 gastric carcinoids: small tumor or larger problem?

scientific article published in January 2004

A Clinical Perspective on Gastric Neuroendocrine Neoplasia ⬇️

scientific article published on February 1, 2011

A Comprehensive Assessment of the Role of miRNAs as Biomarkers in Gastroenteropancreatic Neuroendocrine Tumors.

scientific article published on 22 March 2018

A Delphic consensus assessment: imaging and biomarkers in gastroenteropancreatic neuroendocrine tumor disease management

scientific article published on 31 August 2016

A Nomogram to Assess Small-Intestinal Neuroendocrine Tumor (‘Carcinoid’) Survival ⬇️

scientific article published on August 23, 2010

A PCR blood test outperforms chromogranin A in carcinoid detection and is unaffected by proton pump inhibitors

scientific article published on 14 October 2014

A century of Helicobacter pylori: paradigms lost-paradigms regained

scientific article

A comparison of the effects of gastrin, somatostatin and dopamine receptor ligands on rat gastric enterochromaffin-like cell secretion and proliferation

scientific journal article

A historical appreciation of bronchopulmonary neuroendocrine neoplasia: resolution of a carcinoid conundrum

scientific article published in August 2014

A liquid biopsy for bronchopulmonary/lung carcinoid diagnosis

scientific article published on 29 December 2017

A metastatic tumor is no different to a viral pandemic: lessons learnt from COVID-19 may teach us to change the PRRT paradigm

scientific article published on 20 June 2020

A multianalyte PCR blood test outperforms single analyte ELISAs (chromogranin A, pancreastatin, neurokinin A) for neuroendocrine tumor detection.

scientific article

A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors

scientific article published on 18 June 2018

A three-decade analysis of 3,911 small intestinal neuroendocrine tumors: the rapid pace of no progress

scientific article published on 27 March 2007

Altered influence of CCK-B/gastrin receptors on HDC expression in ECL cells after neoplastic transformation

scientific article

An Assessment of Circulating Chromogranin A as a Biomarker of Bronchopulmonary Neuroendocrine Neoplasia: A Systematic Review and Meta-Analysis

scientific article published on 05 July 2019

An analysis of rare carcinoid tumors: clarifying these clinical conundrums

scientific article

Are enterochromaffinlike cell tumours reversible? An experimental study on gastric carcinoids induced in Mastomys by histamine2-receptor blockade

scientific article published on 01 March 1995

Aspects on diagnosis and treatment of the foregut carcinoid syndrome

scientific article published on 01 June 1992

Autoregulatory effects of serotonin on proliferation and signaling pathways in lung and small intestine neuroendocrine tumor cell lines

scientific article

Biology and management of gastric carcinoid tumours: a review

scientific article published in January 2002

Biology and management of the midgut carcinoid

scientific article

Blood Chromogranin A Is Not Effective as a Biomarker for Diagnosis or Management of Bronchopulmonary Neuroendocrine Tumors/Neoplasms.

scientific article

Blood and tissue neuroendocrine tumor gene cluster analysis correlate, define hallmarks and predict disease status

scientific article

Blood mRNA Measurement (NETest) for Neuroendocrine Tumors diagnosis of Image-negative liver metastatic disease

scientific article published on 01 March 2019

Blood measurement of neuroendocrine gene transcripts defines the effectiveness of operative resection and ablation strategies.

scientific article published on 9 October 2015

Blood transcript analysis and metastatic recurrent small bowel carcinoid management

scientific article

Bronchopulmonary neuroendocrine tumors

scientific article

CURRENT CONCEPTS IN (68)Ga-DOTATATE NEN IMAGING: INTERPRETATION, BIODISTRIBUTION, DOSIMETRY AND MOLECULAR STRATEGIES.

scientific article

Carcinoid tumors and fibrosis: an association with no explanation

scientific article

Carcinoid tumors of the stomach

scientific article

Carcinoids of the rectum

scientific article published on August 1994

Caveat Emptor: Let Our Acclaim of the Apotheosis of PRRT Not Blind Us to the Error of Prometheus

scientific article published on 01 January 2019

Chromogranin A--biological function and clinical utility in neuro endocrine tumor disease

scientific article published on 09 March 2010

Chromogranin A: any relevance in neuroendocrine tumors?

scientific article

Circulating Transcript Analysis (NETest) in GEP-NETs Treated With Somatostatin Analogs Defines Therapy.

scientific article

Comparison of PCR-based detection of chromogranin A mRNA with traditional histological lymph node staging of small intestinal neuroendocrine neoplasia

scientific article

Decoding the Molecular and Mutational Ambiguities of Gastroenteropancreatic Neuroendocrine Neoplasm Pathobiology.

scientific article published on 12 January 2015

Delineation of the chemomechanosensory regulation of gastrin secretion using pure rodent G cells

scientific article published on 14 January 2009

Differential signal pathway activation and 5-HT function: the role of gut enterochromaffin cells as oxygen sensors

scientific article published on 30 August 2012

Evolution of one-handed piano compositions.

scientific article

Evolution of the diffuse neuroendocrine system--clear cells and cloudy origins

scientific article published on 9 November 2006

Friedrich Feyrter: a precise intellect in a diffuse system

scientific article

From Leningrad to London: the saga of Kulchitsky and the legacy of the enterochromaffin cell

scientific article

From the lumen to the laparoscope

scientific article

Further delineation of the continuous human neoplastic enterochromaffin cell line, KRJ-I, and the inhibitory effects of lanreotide and rapamycin

scientific article published on February 2007

Gastric stem cells: an update.

scientific article

Gastroenteropancreatic neuroendocrine tumours

scientific article

Gastroesophageal reflux disease: then and now.

scientific article published on May 2004

Gastrointestinal carcinoids: the evolution of diagnostic strategies

scientific article published on August 2006

Gastrointestinal neuroendocrine (carcinoid) tumours: current diagnosis and management

scientific article published on July 2010

Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia

scientific article

Gene network-based analysis identifies two potential subtypes of small intestinal neuroendocrine tumors

scientific article

Genetic differentiation of appendiceal tumor malignancy: a guide for the perplexed.

scientific article

Global expression analysis of ECL cells in Mastomys natalensis gastric mucosa identifies alterations in the AP-1 pathway induced by gastrin-mediated transformation

scientific article

Gut neuroendocrine tumor blood qPCR fingerprint assay: characteristics and reproducibility.

scientific article published on March 2014

Histamine as an intermediate growth factor in genesis of gastric ECLomas associated with hypergastrinemia in mastomys

scientific article published on 01 July 1994

Histamine metabolism of gastric carcinoids in Mastomys natalensis

scientific article

Histidine decarboxylase expression and histamine metabolism in gastric oxyntic mucosa during hypergastrinemia and carcinoid tumor formation

scientific article published on 01 October 1996

Historical perspectives on the treatment of gastroesophageal reflux disease.

scientific article published in January 2003

How smart is peptide receptor radionuclide therapy of neuroendocrine tumors especially in the salvage setting? The clinician's perspective.

scientific article published in February 2014

Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor ⬇️

scientific article published on July 1, 1992

Improving the diagnosis and management of neuroendocrine tumors: utilizing new advances in biomarker and molecular imaging science

scientific article published on 28 June 2013

In situ RNA-RNA hybridisation of phospholipase C beta 3 shows lack of expression in neuroendocrine tumours.

scientific article

Incidence and mortality of carcinoids of the colon. Data from the Connecticut Tumor Registry

scientific article published on May 15, 1992

Independent modulation of enterocyte migration and proliferation by growth factors, matrix proteins, and pharmacologic agents in an in vitro model of mucosal healing

scientific article published on August 1, 1992

Information assimilation and distribution challenges and goals for real and virtual journals

scientific article

Inhibition of proliferation of small intestinal and bronchopulmonary neuroendocrine cell lines by using peptide analogs targeting receptors.

scientific article

KRJ-I and BON cell lines: defining an appropriate enterochromaffin cell neuroendocrine tumor model.

scientific article published on 18 March 2009

Lester R. Dragstedt and his role in the evolution of therapeutic vagotomy in the United States

scientific article published in March 1994

Limitations in small intestinal neuroendocrine tumor therapy by mTor kinase inhibition reflect growth factor-mediated PI3K feedback loop activation via ERK1/2 and AKT.

scientific article published on 8 March 2011

Long-term tolerability of PRRT in 807 patients with neuroendocrine tumours: the value and limitations of clinical factors

scientific article published on 2 October 2014

Luminal regulation of normal and neoplastic human EC cell serotonin release is mediated by bile salts, amines, tastants, and olfactants

scientific article

Management of unresectable malignant endocrine tumors of the pancreas.

scientific article

Measurement of circulating transcript levels (NETest) to detect disease recurrence and improve follow-up after curative surgical resection of well-differentiated pancreatic neuroendocrine tumors

scientific article published on 01 July 2018

Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies

scientific article

Microsatellite instability and gene mutations in transforming growth factor-beta type II receptor are absent in small bowel carcinoid tumors

scientific article published on 01 January 2005

Molecular mechanisms in therapy of acid-related diseases

scientific article

Molecular profiling of neuroendocrine tumours to predict response and toxicity to peptide receptor radionuclide therapy

scientific article published on 01 September 2020

Molecular strategies in the management of bronchopulmonary and thymic neuroendocrine neoplasms

scientific article published in November 2017

Multiple gastric carcinoids

scientific article published on 01 January 2004

Myeloid neoplasms after chemotherapy and PRRT: myth and reality

scholarly article by Lisa Bodei et al published August 2016 in Endocrine-related cancer

NET Blood Transcript Analysis Defines the Crossing of the Clinical Rubicon: When Stable Disease Becomes Progressive

scientific article published on 15 April 2016

Neuroendocrine Tumor Omic Gene Cluster Analysis Amplifies the Prognostic Accuracy of the NETest

scientific article published on 11 May 2020

Neuroendocrine neoplasms of the small bowel and pancreas

scientific article published on 27 September 2019

Neuroendocrine tumor biomarkers: From monoanalytes to transcripts and algorithms

scientific article published on 18 January 2016

Neuroendocrine tumor biomarkers: current status and perspectives.

scientific article published on 2 October 2014

Neuroendocrine tumors of the diffuse neuroendocrine system

scientific article published on January 2008

Neuroendocrine tumors of the gallbladder: an evaluation and reassessment of management strategy

scientific article

New Pharmacologic Therapies for Gastroenteropancreatic Neuroendocrine Tumors ⬇️

scientific article published on September 1, 2010

Nikolai Konstantinovich Kulchitsky (1856-1925).

scientific article

Oddi: the paradox of the man and the sphincter

scientific article

PRRT genomic signature in blood for prediction of 177Lu-octreotate efficacy.

scientific article published on 26 February 2018

PRRT neuroendocrine tumor response monitored using circulating transcript analysis: the NETest

scientific article published on 14 December 2019

PRRT: Defining the paradigm shift to achieve standardization and individualization

scientific article published on 25 September 2014

Parietal cell activation by arborization of ECL cell cytoplasmic projections is likely the mechanism for histamine induced secretion of hydrochloric acid

scientific journal article

Peptide Receptor Radionuclide Therapy of Neuroendocrine Tumors

scientific article published on 14 August 2015

Peptide receptor radionuclide therapy for advanced neuroendocrine tumors

scientific article

Praomys (Mastomys) natalensis: a model for gastric carcinoid formation ⬇️

scientific article published on November 1, 1992

Predicting the survival of patients with small bowel neuroendocrine tumours: comparison of 3 systems.

scientific article

Primary carcinoid tumor of the parotid gland: A case report and review of the literature

scientific article published on August 2006

Q RT-PCR detection of chromogranin A: a new standard in the identification of neuroendocrine tumor disease

scientific article published on February 2006

Radiolabeled Somatostatin Analogue Therapy Of Gastroenteropancreatic Cancer

scientific article published on May 2016

Rapid induction of enterochromaffinlike cell tumors by histamine2-receptor blockade

scientific article published on April 1993

Recommendations for management of patients with neuroendocrine liver metastases

scientific article published on January 2014

Review article: from gastrin to gastro-oesophageal reflux disease--a century of acid suppression

scientific article (publication date: 15 March 2006)

Serotonin and the 5-HT7 receptor: the link between hepatocytes, IGF-1 and small intestinal neuroendocrine tumors

scientific article published on 24 May 2013

Siegfried Oberndorfer: origins and perspectives of carcinoid tumors

scientific article

Siegfried oberndorfer and the evolution of carcinoid disease

scientific article

Small bowel carcinoid (enterochromaffin cell) neoplasia exhibits transforming growth factor-beta1-mediated regulatory abnormalities including up-regulation of C-Myc and MTA1.

scientific article published on June 2007

Small intestinal neuroendocrine cell pathobiology: 'carcinoid' tumors

scientific article published on January 1, 2011

Surgery of chronic pancreatitis: chronicle of confusion and despair

scientific article published on 6 September 2002

Symptom evaluation in gastroesophageal reflux disease

scientific article published on May 2008

Systemic therapeutic options for carcinoid

scientific article published on February 2013

The Lester Dragstedt centennial.

scientific article published in July 1994

The NETest: The Clinical Utility of Multigene Blood Analysis in the Diagnosis and Management of Neuroendocrine Tumors

scientific article published on 01 September 2018

The Path to the Future: Education of Nuclear Medicine Therapeutic Specialists as Responsible Physicians

scientific article published on 15 November 2019

The archaic distinction between functioning and nonfunctioning neuroendocrine neoplasms is no longer clinically relevant

scientific article published on 27 April 2011

The centenary of Lester Dragstedt--fifty years of therapeutic vagotomy

scientific article published on May 1994

The clinical applications of a multigene liquid biopsy (NETest) in neuroendocrine tumors

scientific article published on 13 December 2019

The clinical relevance of chromogranin A as a biomarker for gastroenteropancreatic neuroendocrine tumors

scientific article published on March 2011

The diversity and commonalities of gastroenteropancreatic neuroendocrine tumors

scientific article published on 28 January 2011

The effect of vagotomy on enterochromaffin-like cells in Mastomys natalensis

scientific article published on 01 July 1996

The functional characterization of normal and neoplastic human enterochromaffin cells

scientific article published on 14 March 2006

The future of nuclear medicine imaging of neuroendocrine tumors: on a clear day one might see forever....

scientific article published in December 2014

The identification of gut neuroendocrine tumor disease by multiple synchronous transcript analysis in blood

scientific article

The molecular genetics of gastroenteropancreatic neuroendocrine tumors

scientific article published in December 2005

The role of genetic markers--NAP1L1, MAGE-D2, and MTA1--in defining small-intestinal carcinoid neoplasia.

scientific article

The role of mechanical forces and adenosine in the regulation of intestinal enterochromaffin cell serotonin secretion

scientific article

The role of peptide receptor radionuclide therapy in advanced/metastatic thoracic neuroendocrine tumors.

scientific article published in November 2017

The status of neuroendocrine tumor imaging: from darkness to light?

scientific article published on 10 September 2014

The use of Deep Learning and Neural Networks in Imaging - Welcome to the new Mathematical Milieu of Medicine

scientific article published on 07 November 2019

The utility of blood neuroendocrine gene transcript measurement in the diagnosis of bronchopulmonary neuroendocrine tumours and as a tool to evaluate surgical resection and disease progression

scientific article published on 13 November 2017

Therapeutic options for gastrointestinal carcinoids

scientific article

Towards a new classification of gastroenteropancreatic neuroendocrine neoplasms

scientific article

Unique permeability barrier of the apical surface of parietal and chief cells in isolated perfused gastric glands

scientific article

Utility of a ready-to-use PCR system for neuroendocrine tumor diagnosis

scientific article published on 27 June 2019

Utility of molecular genetic signatures in the delineation of gastric neoplasia

scientific article published on 01 April 2006

Whistler summary: "the slow rate of rapid progress"

scientific article published on 01 July 2007

Whither peptide receptor radionuclide therapy for neuroendocrine tumors: an Einsteinian view of the facts and myths

article

Why wait for posterity (or the future) to provide proof to savor the elixir of precision oncology? Read interviews with intellects and dine with the doyens of discovery

scientific article published on 01 November 2019

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