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List of works by Dyana Saenz

A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection

scientific article

An essential role for LEDGF/p75 in HIV integration

scientific article

Antiviral restriction factor transgenesis in the domestic cat

scientific article

BET protein bromodomain inhibitor-based combinations are highly active against post-myeloproliferative neoplasm secondary AML cells

scientific article published on 28 September 2016

BET protein proteolysis targeting chimera (PROTAC) exerts potent lethal activity against mantle cell lymphoma cells

scientific article published on 30 June 2017

Comparison of wild-type and class I integrase mutant-FIV vectors in retina demonstrates sustained expression of integrated transgenes in retinal pigment epithelium

scientific article

Construction and Testing of orfA +/- FIV Reporter Viruses

scientific article published on January 23, 2012

Durable, safe, multi-gene lentiviral vector expression in feline trabecular meshwork

scientific article published on 2 October 2007

FIV Vectors

scientific article published on 01 January 2003

FIV: from lentivirus to lentivector

scientific article

Feline Immunodeficiency Virus Gag Is a Nuclear Shuttling Protein

Feline immunodeficiency virus Gag is a nuclear shuttling protein

scientific article published on 23 May 2012

Feline immunodeficiency virus envelope glycoproteins antagonize tetherin through a distinctive mechanism that requires virion incorporation.

scientific article

Feline immunodeficiency virus-based lentiviral vectors

scientific article published on January 2012

Functional cloning of recurrence-specific antigens identifies molecular targets to treat tumor relapse

scientific article

High-throughput screening for growth inhibitors using a yeast model of familial paraganglioma

scientific article

Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration

scientific article

Intensive RNAi with lentiviral vectors in mammalian cells

scientific article

LEDGF dominant interference proteins demonstrate prenuclear exposure of HIV-1 integrase and synergize with LEDGF depletion to destroy viral infectivity

scientific article

LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

scientific article

LEDGF/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors

scientific article

Mechanistic basis and efficacy of targeting β-catenin-TCF7L2-JMJD6-MYC axis to overcome resistance to BET inhibitors

scientific article published on 14 February 2020

Novel BET protein proteolysis-targeting chimera exerts superior lethal activity than bromodomain inhibitor (BETi) against post-myeloproliferative neoplasm secondary (s) AML cells

scientific article published on 2 January 2017

Production and harvest of feline immunodeficiency virus-based lentiviral vector from cells grown in T75 tissue-culture flasks.

scientific article

Production, harvest, and concentration of feline immunodeficiency virus-based lentiviral vector from cells grown in CF10 or CF2 devices.

scientific article

Productive replication and evolution of HIV-1 in ferret cells.

scientific article published on 14 December 2011

Productive replication of Vif-chimeric HIV-1 in feline cells

scientific article

RUNX1-targeted therapy for AML expressing somatic or germline mutation in RUNX1

scientific article published on 25 April 2019

Restriction of feline immunodeficiency virus by Ref1, Lv1, and primate TRIM5alpha proteins

scientific article

Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting

scientific article

SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents.

scientific article published on 8 August 2016

Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells

scholarly article by Warren Fiskus et al published 15 January 2019 in Blood Cancer Journal

Synergistic activity of BET protein antagonist-based combinations in mantle cell lymphoma cells sensitive or resistant to ibrutinib

scientific article

TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism

scientific article

Targeting nuclear β-catenin as therapy for post-myeloproliferative neoplasm secondary AML

scientific article published on 21 December 2018

The HIV-1 Central Polypurine Tract Functions as a Second Line of Defense against APOBEC3G/F

scientific article published on September 15, 2010

The HIV-1-specific protein Casp8p41 induces death of infected cells through Bax/Bak

scientific article

Titration of feline immunodeficiency virus-based lentiviral vector preparations.

scientific article published in January 2012

Unintegrated lentivirus DNA persistence and accessibility to expression in nondividing cells: analysis with class I integrase mutants

scientific article published on March 2004