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List of works by Andreas Leffler

A high-threshold heat-activated channel in cultured rat dorsal root ganglion neurons resembles TRPV2 and is blocked by gadolinium

scientific article

Activation of TRPA1 by Membrane Permeable Local Anesthetics

scientific article published on August 23, 2011

Alternative splicing may contribute to time-dependent manifestation of inherited erythromelalgia

scientific article published on 16 May 2010

Block of sensory neuronal Na+ channels by the secreolytic ambroxol is associated with an interaction with local anesthetic binding sites

scientific article

Erratum: Corrigendum: Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

scholarly article published in Nature Medicine

H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway

scientific article

Lactate is a potent inhibitor of the capsaicin receptor TRPV1.

scientific article published on 9 November 2016

Local anesthetic-like inhibition of voltage-gated Na(+) channels by the partial μ-opioid receptor agonist buprenorphine

scientific article

Methylglyoxal activates nociceptors through transient receptor potential channel A1 (TRPA1): a possible mechanism of metabolic neuropathies

scientific article published on 27 June 2012

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

scientific article

Quaternary Lidocaine Derivative QX-314 Activates and Permeates Human TRPV1 and TRPA1 to Produce Inhibition of Sodium Channels and Cytotoxicity

scientific article published on 9 February 2016

Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures

scientific article

Sodium channelopathies and pain

scientific article published on 26 January 2010

TRPA1 and Substance P Mediate Colitis in Mice

scientific article published on 18 July 2011

The general anesthetic propofol excites nociceptors by activating TRPV1 and TRPA1 rather than GABAA receptors

scientific article published on 7 September 2010

The molecular basis for species-specific activation of human TRPA1 protein by protons involves poorly conserved residues within transmembrane domains 5 and 6.

scientific article published on 24 May 2013

The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons

scientific journal article

Use-dependent block by lidocaine but not amitriptyline is more pronounced in tetrodotoxin (TTX)-Resistant Nav1.8 than in TTX-sensitive Na+ channels

scientific article published on 27 September 2006

[EXPRESS] Etomidate and propylene glycol activate nociceptive TRP ion channels

article