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List of works by Per Eystein Lønning

10th International Aromatase Conference Proceedings, September 2010. Preface

scientific article published on 23 March 2011

A mitochondrial target sequence polymorphism in manganese superoxide dismutase predicts inferior survival in breast cancer patients treated with cyclophosphamide

scientific article published on 09 June 2009

A novel HPLC-RIA method for the simultaneous detection of estrone, estradiol and estrone sulphate levels in breast cancer tissue

scientific article published on 01 April 2000

A novel type of deletion in the CDKN2A gene identified in a melanoma-prone family

scientific article published on December 2006

A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer

scientific article published in March 2004

A sensitive assay for measurement of plasma estrone sulphate in patients on treatment with aromatase inhibitors

scientific article published on 01 December 1995

ABCB1 and GST polymorphisms associated with TP53 status in breast cancer

article published in 2007

APOBEC3A/B deletion polymorphism and cancer risk

scientific article published on 13 November 2017

Absence of p21 expression is associated with abnormal p53 in human breast carcinomas

scientific article

Accidental hypothermia. Review of the literature

scientific article

Activation of Akt characterizes estrogen receptor positive human breast cancers which respond to anthracyclines

scientific article published on 17 April 2017

Activity of exemestane in metastatic breast cancer after failure of nonsteroidal aromatase inhibitors: a phase II trial

scientific article

Additive endocrine therapy for advanced breast cancer - back to the future

scientific article published on January 2009

Adeno-associated viral vectors penetrate human solid tumor tissue in vivo more effectively than adenoviral vectors

scientific article published on June 2002

Adeno-associated virus (AAV) serotypes 2, 4 and 5 display similar transduction profiles and penetrate solid tumor tissue in models of human glioma

scientific article published on September 2006

Adjuvant aromatase inhibitors for early breast cancer after chemotherapy-induced amenorrhoea: caution and suggested guidelines

scientific article published on 01 June 2006

Adjuvant endocrine treatment of early breast cancer

scientific article published on April 2007

Adjuvant treatment: the contribution of expression microarrays

scientific article

Alterations in the insulin-like growth factor system during the menstrual cycle in normal women

scientific article published in January 1998

Alterations in the insulin-like growth factor system during treatment with diethylstilboestrol in patients with metastatic breast cancer

scientific article

Alterations in the metabolism of oestrogens during treatment with aminoglutethimide in breast cancer patients. Preliminary findings

scientific article published on 01 December 1987

Alterations in the p53 pathway and p16INK4a expression predict overall survival in metastatic melanoma patients treated with dacarbazine

scientific article published on 27 May 2010

Alterations in the production rate and the metabolism of oestrone and oestrone sulphate in breast cancer patients treated with aminoglutethimide

scientific article

Alterations in the urine excretion of estrogen metabolites in breast cancer women treated with aminoglutethimide

scientific article published on 01 October 1989

Alterations of the retinoblastoma gene in metastatic breast cancer

scientific article

Alternative splicing and mutation status of CHEK2 in stage III breast cancer

scientific article

Aminoglutethimide and warfarin. A new important drug interaction

scientific article published on 01 January 1984

Aminoglutethimide as an inducer of microsomal enzymes. Part 1: Pharmacological aspects

scientific article published on 01 January 1986

Aminoglutethimide as an inducer of microsomal enzymes. Part 2: Endocrine aspects

scientific article published on 01 January 1986

Aminoglutethimide enzyme induction: pharmacological and endocrinological implications

scientific article published on 01 January 1990

Amplification of TOP2A and HER-2 genes in breast cancers occurring in patients harbouring BRCA1 germline mutations

scientific article

An Ultrasensitive Routine LC-MS/MS Method for Estradiol and Estrone in the Clinically Relevant Sub-Picomolar Range

scientific article published on 21 April 2020

An optimised, highly sensitive radioimmunoassay for the simultaneous measurement of estrone, estradiol and estrone sulfate in the ultra-low range in human plasma samples

scientific article

Anastrozole--a new generation in aromatase inhibition: clinical pharmacology

scientific article published on January 1997

Angiogenesis does not predict clinical response to doxorubicin monotherapy in patients with locally advanced breast cancer

scientific article published on 01 February 1997

Antitumor efficacy improved by local delivery of species-specific endostatin

scientific article published in January 2006

Are current development programs realising the full potential of new agents? ⬇️

scientific article published on December 20, 2010

Aromatase activity, serum oestradiol and their correlation with demographic indices

scientific article published in March 1992

Aromatase inhibition 2013: clinical state of the art and questions that remain to be solved

scientific article published on 24 June 2013

Aromatase inhibition for breast cancer treatment

scientific article published on January 1996

Aromatase inhibition versus placebo

scientific article published in August 2008

Aromatase inhibition: translation into a successful therapeutic approach

scientific article

Aromatase inhibitors and inactivators for breast cancer therapy

scientific article

Aromatase inhibitors and inactivators for breast cancer treatment

scientific article published on 01 November 2002

Aromatase inhibitors and inactivators in breast cancer ⬇️

scientific article published on October 20, 2001

Aromatase inhibitors and their future role in post-menopausal women with early breast cancer ⬇️

scientific article published on September 1, 1998

Aromatase inhibitors as adjuvant treatment of breast cancer

scientific article

Aromatase inhibitors in breast cancer

scientific article published on 01 June 2004

Aromatase inhibitors in malignant diseases of aging

scientific article published on November 1992

Aromatase inhibitors in the therapy for breast cancer

scientific article

Aromatase inhibitors in the treatment of early and advanced breast cancer

scientific article

Aromatase inhibitors--socio-economical issues

scientific article published on 01 May 2005

Aromatase inhibitors--socioeconomical issues

scientific article published on 24 May 2007

Aromatase inhibitors: are there differences between steroidal and nonsteroidal aromatase inhibitors and do they matter?

scientific article published on 11 August 2008

Aromatase inhibitors: assessment of biochemical efficacy measured by total body aromatase inhibition and tissue estrogen suppression

scientific article published on 14 September 2007

Assessment of tumor suppressor promoter methylation in healthy individuals

scientific article published on 28 August 2020

Association of BRAF Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer

Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate

scientific article published on 12 April 2016

BRCA1 methylation in newborns: genetic disposition, maternal transfer, environmental influence, or by chance only?

scientific article published on 22 October 2018

Bone safety of aromatase inhibitors versus tamoxifen

scientific article published on September 2006

Breast cancer aromatase expression evaluated by the novel antibody 677: correlations to intra-tumor estrogen levels and hormone receptor status

scientific article published on 31 October 2009

Breast cancer prognostication and prediction in the postgenomic era.

scientific article published on 21 February 2007

Breast cancer prognostication and prediction: are we making progress?

scientific article published on September 2007

Buparlisib plus fulvestrant in postmenopausal women with hormone-receptor-positive, HER2-negative, advanced breast cancer progressing on or after mTOR inhibition (BELLE-3): a randomised, double-blind, placebo-controlled, phase 3 trial

scientific article published on 6 December 2017

C/EBPB-dependent adaptation to palmitic acid promotes tumor formation in hormone receptor negative breast cancer

scientific article

CHEK2 mutations affecting kinase activity together with mutations in TP53 indicate a functional pathway associated with resistance to epirubicin in primary breast cancer

scientific article

CYP17 and breast cancer risk: the polymorphism in the 5' flanking area of the gene does not influence binding to Sp-1

scientific article published on 01 June 1999

Cancer therapy targeted at cellular signal transduction mechanisms: strategies, clinical results, and unresolved issues

scientific article published on 18 October 2009

Cell-type-specific responses to chemotherapeutics in breast cancer

scientific article published on June 2004

Changes in bone and lipid metabolism in postmenopausal women with early breast cancer after terminating 2-year treatment with exemestane: a randomised, placebo-controlled study

scientific article published on 11 September 2006

Changes in folate status as determined by reduction in total plasma homocysteine levels during leucovorin modulation of 5-fluorouracil therapy in cancer patients

scientific article published on 01 September 1998

Chemosensitivity and p53; new tricks by an old dog ⬇️

scientific article published on November 6, 2012

Chk2 splice variants express a dominant-negative effect on the wild-type Chk2 kinase activity

scientific article

Clinical efficacy and safety of bevacizumab monotherapy in patients with metastatic melanoma: predictive importance of induced early hypertension

scientific article (publication date: 2012)

Clinical pharmacokinetics of endocrine agents used in advanced breast cancer

scientific article published on May 1992

Clinical trials in breast cancer; do we have the right approaches?

scientific article published on 12 March 2000

Clinico-pharmacological aspects of different hormone treatments

scientific article published in September 2000

Combined treatment with 4-hydroxyandrostenedione and aminoglutethimide: effects on aromatase inhibition and oestrogen suppression

scientific article

Comment on "Towards a personalized approach to aromatase inhibitor therapy: a digital microfluidic platform for rapid analysis of estradiol in core-needle-biopsies" by S. Abdulwahab, A. H. C. Ng, M. D. Chamberlain, H. Ahmado, L.-A. Behan, H. Gomaa,

scientific article published on 01 September 2017

Comments on paper: "Quantitative determination of estrone by liquid chromatography-tandem mass spectrometry in subcutaneous adipose tissue from the breast in postmenopausal women" by Vihma et al

scientific article published on 27 February 2016

Comparing cost/utility of giving an aromatase inhibitor as monotherapy for 5 years versus sequential administration following 2-3 or 5 years of tamoxifen as adjuvant treatment for postmenopausal breast cancer

scientific article published on 2 November 2005

Comparison between aromatase inhibitors and sequential use ⬇️

scientific article published on September 1, 2003

Comparison of methods for pharmacogenomics: SNaPshot, SNPstream UHT, Nanogen, and RFLP.

scientific article published on 17 June 2005

Concerns About Methodology of a Trial Investigating Vaginal Health During Aromatase Inhibitor Therapy for Breast Cancer

Concomitant inactivation of the p53- and pRB- functional pathways predicts resistance to DNA damaging drugs in breast cancer in vivo

scientific article

Constitutional Mosaic Epimutations - a hidden cause of cancer?

scientific article published on 22 March 2019

Controversies in Breast Cancer 2010. Session 6 introduction

scientific article

Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia.

scientific article

Cross-resistance to different aromatase inhibitors in breast cancer treatment

scientific article

DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response

scientific article

DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival

scientific article

DNA methylation status of key cell-cycle regulators such as CDKNA2/p16 and CCNA1 correlates with treatment response to doxorubicin and 5-fluorouracil in locally advanced breast tumors.

scientific article published on 7 October 2014

DNA methylation subgroups in melanoma are associated with proliferative and immunological processes

scientific article published on 6 November 2015

Decreased serum concentrations of tamoxifen and its metabolites induced by aminoglutethimide

scientific article published on 01 September 1990

Determination of aminoglutethimide and N-acetylaminoglutethimide in human plasma by reversed-phase liquid chromatography

scientific article published on 01 January 1984

Determination of droloxifene and two metabolites in serum by high-pressure liquid chromatography

scientific article published on 01 June 1995

Determination of warfarin in human plasma by high performance liquid chromatography and photodiode array detector

Development of aromatase inhibitors and their pharmacologic profile

scientific article

Differential effect of carbamazepine and valproate monotherapy on plasma levels of oestrone sulphate and dehydroepiandrosterone sulphate in male epileptic patients

scientific article published on 01 May 1997

Differential inhibition of ex-vivo tumor kinase activity by vemurafenib in BRAF(V600E) and BRAF wild-type metastatic malignant melanoma

scientific article (publication date: 2013)

Disease-related outcomes with long-term follow-up: an updated analysis of the intergroup exemestane study

scientific article published on 31 October 2011

Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer

scientific article

Distribution of tamoxifen and metabolites into brain tissue and brain metastases in breast cancer patients

scientific article

Divergent Activity of the Pseudogene PTENP1 in ER-Positive and Negative Breast Cancer

scientific article

Does adjuvant therapy with letrozole improve survival in postmenopausal women with early-stage breast cancer?

scientific article published on 01 July 2006

Dose response evaluation. Use of plasma concentration confidence intervals as a tool to predict optimal drug dose ratio

scientific article published on 01 July 1993

Double KRAS and BRAF Mutations in Surgically Treated Colorectal Cancer Liver Metastases: An International, Multi-institutional Case Series

scientific article published in May 2018

Effect of CYP19 rs6493497 and rs7176005 haplotype status on in vivo aromatase transcription, plasma and tissue estrogen levels in postmenopausal women

scientific article published on 16 September 2011

Effect of aminoglutethimide on antipyrine, theophylline, and digitoxin disposition in breast cancer

scientific article published on 01 December 1984

Effect of estradiol and progesterone on the adenylate cyclase activity in grafts of 3-methylcholanthrene induced carcinomas in the mouse uterine cervix

scientific article published on 01 March 1980

Effect of methotrexate on homocysteine and other sulfur compounds in tissues of rats fed a normal or a defined, choline-deficient diet

scientific article published on 01 January 1988

Effect of the MDM2 promoter polymorphisms SNP309T>G and SNP285G>C on the risk of ovarian cancer in BRCA1 mutation carriers

scientific article

Effects of SNP variants in the 17β-HSD2 and 17β-HSD7 genes and 17β-HSD7 copy number on gene transcript and estradiol levels in breast cancer tissue.

scientific article

Effects of aminoglutethimide on plasma estrone sulfate not caused by aromatase inhibition

scientific article published in October 1989

Effects of anastrozole on the intratumoral gene expression in locally advanced breast cancer

scientific article

Effects of concomitant inactivation of p53 and pRb on response to doxorubicin treatment in breast cancer cell lines

scientific article published on 22 May 2017

Effects of exemestane administered for 2 years versus placebo on bone mineral density, bone biomarkers, and plasma lipids in patients with surgically resected early breast cancer

scientific article published on 27 June 2005

Effects of hormones on the plasma levels of the atherogenic amino acid homocysteine

scientific article published on February 1997

Effects of oral and transdermal oestrogen replacement therapy on plasma levels of insulin-like growth factors and IGF binding proteins 1 and 3: a cross-over study

scientific article published in December 1996

Effects of tamoxifen and octreotide LAR on the IGF-system compared with tamoxifen monotherapy

scientific article

Effects of theMDM2promoter SNP285 and SNP309 on Sp1 transcription factor binding and cancer risk ⬇️

scientific article published on September 1, 2011

Effects of treatment with megestrol acetate on the insulin-like growth factor system: time and dose dependency

scientific article published on 01 July 1999

Effects of treatment with megestrol acetate, aminoglutethimide, or formestane on insulin-like growth factor (IGF) I and II, IGF-binding proteins (IGFBPs), and IGFBP-3 protease status in patients with advanced breast cancer

scientific article published on 01 June 1996

Elevated levels of the steroidogenic factor 1 are associated with over-expression of CYP19 in an oestrogen-producing testicular Leydig cell tumour

scientific article published on February 2012

Endocrine Treatment - 'Old-Fashioned' Therapy Becoming Redundant in an Era of Molecular Medicine?

scientific article

Endocrine and clinical effects of exemestane (PNU 155971), a novel steroidal aromatase inhibitor, in postmenopausal breast cancer patients: a phase I study

scientific article

Endocrine effects of aromatase inhibitors

scientific article published on 19 January 2010

Endocrine effects of aromatase inhibitors and inactivators in vivo: review of data and method limitations

scientific article

Endocrine therapy and bone loss in breast cancer: time to close in the RANK(L)?

scientific article published on 25 August 2008

Endocrine, pharmacokinetic and clinical studies of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione ('pyridoglutethimide') in postmenopausal breast cancer patients

scientific article

Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC.

scientific article published in June 2019

Estradiol measurement in translational studies of breast cancer

scientific article

Estrogens Correlate with PELP1 Expression in ER Positive Breast Cancer

scientific article published on 6 August 2015

Evaluation of MetriGenix custom 4D arrays applied for detection of breast cancer subtypes

scientific article published on 15 March 2006

Evaluation of applying IHC4 as a prognostic model in the translational study of Intergroup Exemestane Study (IES): PathIES. ⬇️

scientific article published on 24 November 2017

Evaluation of plasma and tissue estrogen suppression with third-generation aromatase inhibitors: of relevance to clinical understanding?

scientific article published on 4 October 2009

Evolution of endocrine adjuvant therapy for early breast cancer

scientific article published on April 2010

Exemestane experience in breast cancer treatment

scientific article published on April 1997

Exemestane for breast cancer prevention: a feasible strategy?

scientific article

Exemestane in breast cancer: current status and future directions.

scientific article

Exemestane: a review of its clinical efficacy and safety

scientific article published on June 2001

Experience with exemestane in the treatment of early and advanced breast cancer

scientific article published on 01 July 2008

Exploring breast cancer estrogen disposition: the basis for endocrine manipulation

scientific article published on 26 July 2011

Exploring the lack of cross-resistance between aromatase inhibitors: evidence for a difference?

scientific article published on March 2008

Expression of full-length p53 and its isoform Deltap53 in breast carcinomas in relation to mutation status and clinical parameters

scientific article

Expression of wild-type and mutated in breast carcinomas

Functional characterisation of p53 mutants identified in breast cancers with suboptimal responses to anthracyclines or mitomycin

scientific article published on March 2013

GSTP1 promoter haplotypes affect DNA methylation levels and promoter activity in breast carcinomas.

scientific article published on July 2008

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

scientific article (publication date: 11 September 2001)

Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer

article

Gene expression profiling of breast cancer in relation to estrogen receptor status and estrogen-metabolizing enzymes: clinical implications.

scientific article

Gene expression profiling-based identification of molecular subtypes in stage IV melanomas with different clinical outcome

scientific article published on 11 May 2010

Genes causing inherited cancer as beacons to identify the mechanisms of chemoresistance

scientific article published on March 2004

Genetic and epigenetic changes in p21 and p21B do not correlate with resistance to doxorubicin or mitomycin and 5-fluorouracil in locally advanced breast cancer

scientific article

Genetic variants of CYP19 (aromatase) and breast cancer risk

scientific article published on 12 March 2000

Genetic variants of CYP19 (aromatase) and breast cancer risk

scientific article published on 01 March 2000

Genetic variation in putative regulatory loci controlling gene expression in breast cancer

scholarly article

Genome-Wide DNA Methylation Analysis in Melanoma Reveals the Importance of CpG Methylation in MITF Regulation

scientific article

Genomic Evolution of Breast Cancer Metastasis and Relapse

scientific article published on August 2017

Genomics in breast cancer-therapeutic implications

scientific article

Genomics-based prognosis and therapeutic prediction in breast cancer

scientific article

Glomeruloid microvascular proliferation is associated with lack of response to chemotherapy in breast cancer

scientific article

Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer

scientific article

Golgi-localized PAQR4 mediates Anti-apoptotic Ceramidase Activity in Breast Cancer

scientific article published on 14 April 2020

Heterogeneous perivascular cell coverage affects breast cancer metastasis and response to chemotherapy

scientific article published on 22 December 2016

High PTEN gene expression is a negative prognostic marker in human primary breast cancers with preserved p53 function

scientific article published on 17 February 2017

High-dose estrogen treatment in postmenopausal breast cancer patients heavily exposed to endocrine therapy

scientific article published in May 2001

Hospital volume and prognosis among Norwegian breast cancer patients enrolled in adjuvant trials

scientific article

Human endotrophin as a driver of malignant tumor growth.

scientific article published on 21 March 2019

IGF-1 and breast cancer.

scientific article

Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers

scientific article

Identification of tamoxifen metabolites in human Hep G2 cell line, human liver homogenate, and patients on long-term therapy for breast cancer

scientific article published on March 1995

Impact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases

scientific article published on 16 March 2016

Impact of aromatase inhibitors on bone health in breast cancer patients

scientific article published on 13 October 2009

Impact of the MDM2 splice-variants MDM2-A, MDM2-B and MDM2-C on cytotoxic stress response in breast cancer cells

scientific article

In vivo inhibition of aromatization by exemestane, a novel irreversible aromatase inhibitor, in postmenopausal breast cancer patients

scientific article published on 01 September 1998

Incomplete Estrogen Suppression With Gonadotropin-Releasing Hormone Agonists May Reduce Clinical Efficacy in Premenopausal Women With Early Breast Cancer

scientific article published on 04 January 2016

Indications and limitations of third-generation aromatase inhibitors

scientific article published on 01 May 2008

Influence of MDM2 SNP309 and SNP285 status on the risk of cancer in the breast, prostate, lung and colon

scientific article published on 10 December 2014

Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer

scientific article published in March 2001

Influence of aminoglutethimide on plasma levels of estrone sulphate and dehydroepiandrosterone sulphate in postmenopausal breast cancer patients

scientific article published on 01 September 1997

Influence of aminoglutethimide on plasma oestrogen levels in breast cancer patients on 4-hydroxyandrostenedione treatment

scientific article published on 01 January 1992

Influence of aminoglutethimide on the metabolism of medroxyprogesterone acetate and megestrol acetate in postmenopausal patients with advanced breast cancer

scientific article published in January 1990

Influence of anastrozole (Arimidex), a selective, non-steroidal aromatase inhibitor, on in vivo aromatisation and plasma oestrogen levels in postmenopausal women with breast cancer

scientific article

Influence of aromatase inhibitors on plasma total homocysteine in postmenopausal breast cancer patients

scientific article published on 01 February 1999

Influence of dexaminoglutethimide, an optical isomer of aminoglutethimide, on the disposition of estrone sulfate in postmenopausal breast cancer patients

scientific article published on 01 August 1998

Influence of droloxifene (3-hydroxytamoxifen), 40 mg daily, on plasma gonadotrophins, sex hormone binding globulin and estrogen levels in postmenopausal breast cancer patients

scientific article published on 01 November 1995

Influence of droloxifene on metastatic breast cancer as first-line endocrine treatment

scientific article published on 01 January 1998

Influence of droloxifene on plasma levels of insulin-like growth factor (IGF)-I, Pro-IGF-IIE, insulin-like growth factor binding protein (IGFBP)-1 and IGFBP-3 in breast cancer patients

scientific article published in February 1996

Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study

scientific article published in February 2002

Influence of plasma estrogen levels on the length of the disease-free interval in postmenopausal women with breast cancer

scientific article published on 01 January 1996

Influence of progestins on serum hormone levels in postmenopausal women with advanced breast cancer--I. General findings

scientific article

Influence of progestins on serum hormone levels in postmenopausal women with advanced breast cancer--II. A differential effect of megestrol acetate and medroxyprogesterone acetate on serum estrone sulfate and sex hormone binding globulin

scientific article published on 01 June 1990

Influence of tamoxifen on plasma levels of insulin-like growth factor I and insulin-like growth factor binding protein I in breast cancer patients ⬇️

scientific article published on September 1, 1992

Influence of tamoxifen on sex hormones, gonadotrophins and sex hormone binding globulin in postmenopausal breast cancer patients

scientific article published on 01 May 1995

Influence of tamoxifen, aminoglutethimide and goserelin on human plasma IGF-I levels in breast cancer patients

scientific article published on 01 March 1992

Influence of treatment with aminoglutethimide on plasma and red-blood-cell glutathione status in breast cancer patients.

scientific article

Influence of treatment with onapristone on the IGF-system in breast cancer patients

scientific article published on 01 August 1998

Influence of treatment with tamoxifen and change in tumor burden on the IGF-system in breast cancer patients

scientific article published on 01 August 1996

Influence of treatment with the anti-oestrogen 3-hydroxytamoxifen (droloxifene) on plasma sex hormone levels in postmenopausal patients with breast cancer.

scientific article published in August 1995

Insulin-like growth factors in breast cancer

scientific article published on January 1996

Interaction between p53 staining and high-dose chemotherapy in breast cancer

scientific article published on 01 April 2006

Interpreting plasma estrogen levels in breast cancer: caution needed

scientific article published on 14 April 2014

Intra-patient Inter-metastatic Genetic Heterogeneity in Colorectal Cancer as a Key Determinant of Survival after Curative Liver Resection.

scientific article

Intratumoral estrogen disposition in breast cancer

scientific article published on 9 March 2010

Inverse regulation of EGFR/HER1 and HER2-4 in normal and malignant human breast tissue

scientific article

Is there a growing role for endocrine therapy in the treatment of breast cancer?

scientific article

Jan Erik Varhaug

scientific article published on 19 February 2018

Kinetics of plasma total homocysteine in patients receiving high-dose methotrexate therapy

scientific article published on 01 September 1998

Lack of complete cross-resistance between different aromatase inhibitors; a real finding in search for an explanation?

scientific article published on 04 December 2008

Lack of diurnal variation in plasma levels of androstenedione, testosterone, estrone and estradiol in postmenopausal women

scientific article published in January 1989

Lapatinib in early breast cancer—questions to be resolved ⬇️

scientific article published on December 10, 2012

Letrozole is superior to anastrozole in suppressing breast cancer tissue and plasma estrogen levels

scientific article

Long-Term Follow-Up of the Intergroup Exemestane Study ⬇️

scientific article published on 3 May 2017

Long-term cultures of bone marrow-derived human mesenchymal stem cells frequently undergo spontaneous malignant transformation

scientific article

Low BRAF and NRAS expression levels are associated with clinical benefit from DTIC therapy and prognosis in metastatic melanoma

scientific article published on 15 May 2013

Low expression levels of ATM may substitute for CHEK2 /TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer

scientific article

MDM2 SNP309 and risk of cervical cancer

scientific article published on 17 April 2014

MDM2 SNP309 and risk of endometrial cancer

scientific article published in April 2013

MDM2 SNP309 and risk of endometrial cancer

scientific article published on 26 June 2014

MDM2 promoter SNP344T>A (rs1196333) status does not affect cancer risk

scientific article

MDM2 promoter SNP55 (rs2870820) affects risk of colon cancer but not breast-, lung-, or prostate cancer

scientific article published on 14 September 2016

MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk

scientific article

MDM2promoter SNP285 and SNP309; phylogeny and impact on cancer risk ⬇️

scientific article published on March 1, 2011

MDM4 SNP34091 (rs4245739) and its effect on breast-, colon-, lung-, and prostate cancer risk

scientific article published on 16 October 2015

MGMT expression levels predict disease stabilisation, progression-free and overall survival in patients with advanced melanomas treated with DTIC.

scientific article published on 10 June 2010

Mapping genetic alterations causing chemoresistance in cancer: identifying the roads by tracking the drivers ⬇️

scientific article published on March 11, 2013

Measurement of Aromatisation by a Urine Technique Suitable for the Evaluation of Aromatase Inhibitorsin Vivo ⬇️

scientific article published on 01 January 1991

Mechanisms of action of aminoglutethimide as endocrine therapy of breast cancer

scientific article published on June 1988

Megestrol acetate versus aminoglutethimide for metastatic breast cancer

scientific article published on 01 November 1989

Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors

scientific article

Microarrays in primary breast cancer--lessons from chemotherapy studies

scientific article published in September 2001

Microencapsulated octreotide pamoate in advanced gastrointestinal and pancreatic cancer: a phase I study

scientific article

Mistletoe in the treatment of cancer

scientific article published in August 1993

Molecular basis for therapy resistance

scientific article published on 24 April 2010

Molecular portraits of human breast tumours

scientific article (publication date: 17 August 2000)

Multilocus analysis of SNP and metabolic data within a given pathway

scientific article

Mutation of GATA3 in human breast tumors

scientific article

Mutations and polymorphisms of the p21B transcript in breast cancer

scientific article published on August 2007

NR2F1 stratifies dormant disseminated tumor cells in breast cancer patients

scientific article published on 16 October 2018

New endocrine drugs for treatment of advanced breast cancer

scientific article published on January 1990

Normal breast tissue estrogen levels

scientific article published on 16 March 2015

Novel Mad2-targeting miR-493-3p controls mitotic fidelity and cancer cells' sensitivity to paclitaxel

scientific article published on 02 March 2016

Nuclear receptor co-activators and HER-2/neu are upregulated in breast cancer patients during neo-adjuvant treatment with aromatase inhibitors

scientific article published on 15 September 2009

Oestrogen suppression--lessons from clinical studies

scientific article published on March 2004

P21/WAF1 mutation and drug resistance to paclitaxel in locally advanced breast cancer

scientific article published on 01 June 2007

P53 and its molecular basis to chemoresistance in breast cancer ⬇️

scientific article published on 08 February 2012

PML-nuclear bodies accumulate DNA in response to polyomavirus BK and simian virus 40 replication

scientific article published in August 2004

Paclitaxel and docetaxel. Innovation, but at what cost?

scientific article published on 01 July 1995

Pathway based analysis of SNPs with relevance to 5-FU therapy: relation to intratumoral mRNA expression and survival.

scientific article

Patterns of genomic evolution in advanced melanoma.

scientific article published on 10 July 2018

Performance comparison of three BRAF V600E detection methods in malignant melanoma and colorectal cancer specimens

scientific article

Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival

scientific article published on 14 August 2012

Pharmacokinetics and metabolism of formestane in breast cancer patients

scientific article published in April 2001

Pharmacokinetics and pharmacodynamics of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione in patients with postmenopausal breast cancer ⬇️

scientific article published on January 1, 1991

Pharmacokinetics of anti-endocrine agents

scientific article

Pharmacokinetics of third-generation aromatase inhibitors.

scientific article published on August 2003

Pharmacological and clinical profile of anastrozole

scientific article published on 01 January 1998

Pharmacological profiles of exemestane and formestane, steroidal aromatase inhibitors used for treatment of postmenopausal breast cancer ⬇️

scientific article published on 01 January 1998

Pharmacology and clinical experience with exemestane

scientific article

Phase III randomized trial of droloxifene and tamoxifen as first-line endocrine treatment of ER/PgR-positive advanced breast cancer

scientific article published in May 2002

Plasma and urinary oestrogens in breast cancer patients on treatment with 4-hydroxyandrostenedione

scientific article

Plasma changes in breast cancer patients during endocrine therapy--lipid measurements and nuclear magnetic resonance (NMR) spectroscopy

scientific article published on 01 January 1995

Plasma estrogen suppression with aromatase inhibitors evaluated by a novel, sensitive assay for estrone sulphate

scientific article published on 01 April 1997

Plasma estrone and estrone sulphate in breast cancer patients treated with the aromatase inhibitor CGS 16949A.

scientific article

Plasma insulin-like growth factor binding protein-3 proteolysis is increased in primary breast cancer

scientific article published on July 2001

Plasma levels of estradiol, estrone, estrone sulfate and sex hormone binding globulin in patients receiving rifampicin

scientific article published on 01 October 1989

Plasma levels of the atherogenic amino acid homocysteine in post-menopausal women with breast cancer treated with tamoxifen

scientific article published on 01 January 1995

Plasma oestrogen fractions in postmenopausal women receiving hormone replacement therapy: influence of route of administration and cigarette smoking

scientific article published on 01 August 1999

Poor-prognosis estrogen receptor- positive disease: present and future clinical solutions ⬇️

scientific article published on May 1, 2012

Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649).

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Postmenopausal estrogen synthesis and metabolism: alterations caused by aromatase inhibitors used for the treatment of breast cancer

scientific article published on March 1990

Predicting long-term survival and treatment response in breast cancer patients receiving neoadjuvant chemotherapy by MR metabolic profiling

scientific article published on 8 August 2011

Predictive and prognostic impact of TP53 mutations and MDM2 promoter genotype in primary breast cancer patients treated with epirubicin or paclitaxel

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Predictive value of tumour cell proliferation in locally advanced breast cancer treated with neoadjuvant chemotherapy

scientific article published in March 2003

Prevalence of the CHEK2 R95* germline mutation ⬇️

scientific article published on 27 September 2016

Primary systemic treatment with weekly doxorubicin monotherapy in women with locally advanced breast cancer; clinical experience and parameters predicting outcome

scientific article published on 01 January 1996

Proceedings of the Fourth International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: conference summary statement.

scientific article published in January 2005

Profound suppression of plasma estrogens by megestrol acetate in postmenopausal breast cancer patients

scientific article published on 01 September 1996

Prognostic Factors Change Over Time After Hepatectomy for Colorectal Liver Metastases: A Multi-institutional, International Analysis of 1099 Patients

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Prognostic and predictive value of ERβ1 and ERβ2 in the Intergroup Exemestane Study (IES)-first results from PathIES†. ⬇️

scientific article published on 22 May 2015

Prognostic and predictive value of changes in tumour cell proliferation in locally advanced breast cancer primarily treated with doxorubicin.

scientific article published in March 2005

Prognostic parameters in localized breast cancer

scientific article published on February 28, 1992

Prognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy

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Prognostic value of plasma prostate specific antigen after megestrol acetate treatment in patients with metastatic breast carcinoma

scientific article published on 01 February 1999

Promyelocytic leukemia nuclear bodies are predetermined processing sites for damaged DNA

scientific article published on 25 July 2006

Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors

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RINF (CXXC5) is overexpressed in solid tumors and is an unfavorable prognostic factor in breast cancer

scientific article published on 16 February 2011

Re: Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine

scientific article published in June 2004

Recent data on intratumor estrogens in breast cancer

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Redox status and protein binding of plasma homocysteine and other aminothiols in patients with early-onset peripheral vascular disease. Homocysteine and peripheral vascular disease

scientific article published in February 1995

Relation of gene expression-based tumor subclasses to clinical phenotypes.

scientific article published on 12 March 2000

Relations between sex hormones, sex hormone binding globulin, insulin-like growth factor-I and insulin-like growth factor binding protein-1 in post-menopausal breast cancer patients

scientific article published in January 1995

Relationship of body mass index with aromatisation and plasma and tissue oestrogen levels in postmenopausal breast cancer patients treated with aromatase inhibitors

scientific article published on 4 February 2014

Repeated observation of breast tumor subtypes in independent gene expression data sets

scientific article (publication date: 8 July 2003)

Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres

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Resistance to endocrine therapy of breast cancer: recent advances and tomorrow's challenges

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Ri antibodies in patients with breast, ovarian or small cell lung cancer determined by a sensitive immunoprecipitation technique

scientific article published on 21 January 2006

SNP285C modulates oestrogen receptor/Sp1 binding to the MDM2 promoter and reduces the risk of endometrial but not prostatic cancer

scientific article published on 24 November 2011

Screening breast cancer patients for Norwegian ATM mutations

scientific article published on December 2000

Screening breast cancer patients for Norwegian ATM mutations

scientific article published on 12 March 2000

Selective oestrogen receptor modifiers (SERMs) and breast cancer therapy

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Separation of urinary metabolites of radiolabelled estrogens in man by HPLC.

scientific article published in January 1989

Serum homocysteine levels in postmenopausal breast cancer patients treated with tamoxifen

scientific article published on 01 October 1999

Single-dose and steady-state pharmacokinetics of aminoglutethimide

scientific article published in July 1985

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

scientific article published on 01 July 1996

Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track - Letter

scientific article published on 14 July 2010

Stepwise estrogen suppression manipulating the estrostat

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Strength and weakness of phase I to IV trials, with an emphasis on translational aspects

scientific article published on 18 December 2008

Study of suboptimum treatment response: lessons from breast cancer

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Subclonal diversification of primary breast cancer revealed by multiregion sequencing

scientific article published on 22 June 2015

Survival and safety of exemestane versus tamoxifen after 2-3 years' tamoxifen treatment (Intergroup Exemestane Study): a randomised controlled trial

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Systemic therapy in breast cancer: efficacy and cost utility

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TP53 and additional pathways in therapy resistance

scientific article published on 17 June 2005

TP53 gene mutations predict the response to neoadjuvant treatment with 5-fluorouracil and mitomycin in locally advanced breast cancer

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TP53 status predicts long-term survival in locally advanced breast cancer after primary chemotherapy

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Tailored targeted therapy for all: a realistic and worthwhile objective?

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The Functional Roles of the MDM2 Splice Variants P2-MDM2-10 and MDM2-∆5 in Breast Cancer Cells

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The IGF-system in healthy pre- and postmenopausal women: relations to demographic variables and sex-steroids

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The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians

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The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian-but not endometrial cancer

scientific article published on 11 February 2016

The Prognostic Impact of Primary Tumor Site Differs According to the KRAS Mutational Status: A Study By the International Genetic Consortium for Colorectal Liver Metastasis

scientific article published on 05 August 2019

The TP53 codon 72 polymorphism may affect the function of TP53 mutations in breast carcinomas but not in colorectal carcinomas.

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The effects of oral 4-hydroxyandrostenedione on peripheral aromatisation in post-menopausal breast cancer patients

scientific article published on 01 January 1995

The emergence of targeted drugs in breast cancer to prevent resistance to endocrine treatment and chemotherapy

scientific article published on 28 February 2014

The influence of CGS 16949A on peripheral aromatisation in breast cancer patients

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The influence of a graded dose schedule of aminoglutethimide on the disposition of the optical enantiomers of warfarin in patients with breast cancer

scientific article published on 01 January 1986

The influence of aminoglutethimide and its analogue rogletimide on peripheral aromatisation in breast cancer ⬇️

scientific article published on October 1, 1992

The influence of intramuscular 4-hydroxyandrostenedione on peripheral aromatisation in breast cancer patients

scientific article published on 01 January 1992

The insulin-like growth factor system in human immunodeficiency virus infection: relations to immunological parameters, disease progression, and antiretroviral therapy

scientific article published in January 2001

The multitude of molecular analyses in cancer: the opening of Pandora’s box.

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The novel microRNAs hsa-miR-nov7 and hsa-miR-nov3 are over-expressed in locally advanced breast cancer

scientific article published on 16 April 2020

The novel p21 polymorphism p21G251A is associated with locally advanced breast cancer

scientific article published in October 2006

The optimal cut-off values for tumor size, number of lesions, and CEA levels in patients with surgically treated colorectal cancer liver metastases: An international, multi-institutional study

scientific article published on 05 January 2021

The potency and clinical efficacy of aromatase inhibitors across the breast cancer continuum

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The potential for aromatase inhibition in breast cancer prevention

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The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling

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The prognosis of colorectal cancer liver metastases associated with inflammatory bowel disease: An exploratory analysis

scientific article published on 27 September 2018

The relation between cell proliferation and adenylate cyclase activity in grafts of 3-methylcholanthrene induced mouse uterine cervical tumors

scientific article published on 01 March 1982

The role of aromatase inactivators in the treatment of breast cancer

scientific article

Thyroid function in postmenopausal breast cancer patients treated with tamoxifen

scientific article published on 01 April 1998

Tissue estradiol is selectively elevated in receptor positive breast cancers while tumour estrone is reduced independent of receptor status.

scientific article published on 8 July 2009

Total body aromatization in postmenopausal breast cancer patients is strongly correlated to plasma leptin levels

scientific article

Trastuzumab in adjuvant breast cancer therapy. A model based cost-effectiveness analysis

scientific article published on 01 January 2007

Treatment of Early Breast Cancer with Conservation of the Breast a Review ⬇️

scientific article published on January 1, 1991

Treatment of breast cancer with aromatase inhibitors--current status and future prospects

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Treatment of breast carcinoma with aminoglutethimide.

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Treatment of relapse of breast cancer after adjuvant systemic therapy--review and guidelines for future research

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Treatment with aromatase inhibitors stimulates the expression of epidermal growth factor receptor-1 and neuregulin 1 in ER positive/HER-2/neu non-amplified primary breast cancers

scientific article published on 22 June 2016

Treatment with formestane alone and in combination with aminoglutethimide in heavily pretreated breast cancer patients: clinical and endocrine effects

scientific article published on 01 May 1996

Treatment with high-dose estrogen (diethylstilbestrol) significantly decreases plasma estrogen and androgen levels but does not influence in vivo aromatization in postmenopausal breast cancer patients

scientific article published in September 2005

Use of aromatase inhibitors and bisphosphonates as an anticancer therapy in postmenopausal breast cancer.

scientific article published on 30 September 2010

Vascular proliferation is a prognostic factor in breast cancer

article

White Blood Cell BRCA1 Promoter Methylation Status and Ovarian Cancer Risk

scientific article published on 16 January 2018

Widespread dispersion of adeno-associated virus serotype 1 and adeno-associated virus serotype 6 vectors in the rat central nervous system and in human glioblastoma multiforme xenografts

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X chromosome inactivation in cervical cancer patients

scientific article published on 01 October 2003

Yo antibodies in ovarian and breast cancer patients detected by a sensitive immunoprecipitation technique

scientific article published on 01 April 2006

[Endocrine therapy of progressive breast carcinoma]

scientific article published on 01 February 1995

[Genome sequencing for personalized cancer treatment].

scientific article

[Primary treatment of locally advanced breast cancer with neoadjuvant chemotherapy]

scientific article published on 01 February 1994

[Treatment of advanced breast cancer with aminoglutethimide]

scientific article published on 01 November 1984

p16INK4A as a predictive factor in patients with locally advanced breast cancer treated with neoadjuvant doxorubicin monotherapy.

scientific article published on 12 March 2000

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