List of works - Christopher G Mowat

Altered substrate specificity in flavocytochrome b2: structural insights into the mechanism of L-lactate dehydrogenation

scientific article

Antitumour agents as inhibitors of tryptophan 2,3-dioxygenase

scientific article

Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450

scientific article

Crystallization and preliminary crystallographic analysis of a novel cytochrome P450 from Mycobacterium tuberculosis

scientific article published on 22 March 2002

Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis.

scientific article

Engineering water to act as an active site acid catalyst in a soluble fumarate reductase

scientific article

Exploring the mechanism of tryptophan 2,3-dioxygenase

scientific article

Flavin-containing heme enzymes

scientific article published on 19 October 2009

Fumarate reductase: structural and mechanistic insights from the catalytic reduction of 2-methylfumarate

scientific article published on 17 February 2006

Heme-containing dioxygenases involved in tryptophan oxidation.

scientific article published on 20 February 2012

Histidine 55 of tryptophan 2,3-dioxygenase is not an active site base but regulates catalysis by controlling substrate binding

scientific article

Histidine 61: an important heme ligand in the soluble fumarate reductase from Shewanella frigidimarina

scientific article

Insights into the mechanism of inhibition of tryptophan 2,3-dioxygenase by isatin derivatives.

scientific article

Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis

scientific article

Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase

scientific article

Multi-heme cytochromes--new structures, new chemistry

scientific article published on 26 September 2005

Octaheme tetrathionate reductase is a respiratory enzyme with novel heme ligation

scientific article published on 7 September 2004

Oxygen activation and electron transfer in flavocytochrome P450 BM3

scientific article

Probing domain mobility in a flavocytochrome

scientific article published in May 2004

Probing the ternary complexes of indoleamine and tryptophan 2,3-dioxygenases by cryoreduction EPR and ENDOR spectroscopy

scientific article published on April 2010

Reassessment of the reaction mechanism in the heme dioxygenases.

scientific article

Rhodobacter sphaeroides haem protein: a novel cytochrome with nitric oxide dioxygenase activity

scientific article

Role of His505 in the soluble fumarate reductase from Shewanella frigidimarina

scientific article

Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase

scientific article published on 12 June 2017

Structure and reaction mechanism in the heme dioxygenases.

scientific article

The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis

scientific article published on 09 March 2017

The mechanism of formation of N-formylkynurenine by heme dioxygenases.

scientific article

The mechanism of substrate inhibition in human indoleamine 2,3-dioxygenase

scientific article published on 2 February 2012

The role of Thr268 and Phe393 in cytochrome P450 BM3.

scientific article

List of works by Christopher G Mowat

Altered substrate specificity in flavocytochrome b2: structural insights into the mechanism of L-lactate dehydrogenation

Antitumour agents as inhibitors of tryptophan 2,3-dioxygenase

Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450

Crystallization and preliminary crystallographic analysis of a novel cytochrome P450 from Mycobacterium tuberculosis

Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis.

Engineering water to act as an active site acid catalyst in a soluble fumarate reductase

Exploring the mechanism of tryptophan 2,3-dioxygenase

Flavin-containing heme enzymes

Fumarate reductase: structural and mechanistic insights from the catalytic reduction of 2-methylfumarate

Heme-containing dioxygenases involved in tryptophan oxidation.

Histidine 55 of tryptophan 2,3-dioxygenase is not an active site base but regulates catalysis by controlling substrate binding

Histidine 61: an important heme ligand in the soluble fumarate reductase from Shewanella frigidimarina

Insights into the mechanism of inhibition of tryptophan 2,3-dioxygenase by isatin derivatives.

Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis

Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase

Multi-heme cytochromes--new structures, new chemistry

Octaheme tetrathionate reductase is a respiratory enzyme with novel heme ligation

Oxygen activation and electron transfer in flavocytochrome P450 BM3

Probing domain mobility in a flavocytochrome

Probing the ternary complexes of indoleamine and tryptophan 2,3-dioxygenases by cryoreduction EPR and ENDOR spectroscopy

Reassessment of the reaction mechanism in the heme dioxygenases.

Rhodobacter sphaeroides haem protein: a novel cytochrome with nitric oxide dioxygenase activity

Role of His505 in the soluble fumarate reductase from Shewanella frigidimarina

Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase

Structure and reaction mechanism in the heme dioxygenases.

The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis

The mechanism of formation of N-formylkynurenine by heme dioxygenases.

The mechanism of substrate inhibition in human indoleamine 2,3-dioxygenase

The role of Thr268 and Phe393 in cytochrome P450 BM3.