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List of works by Leena Hilakivi-Clarke

A maternal diet high in n − 6 polyunsaturated fats alters mammary gland development, puberty onset, and breast cancer risk among female rat offspring ⬇️

scientific article published on August 19, 1997

Adult alcohol consumption after pharmacological intervention in neonatal sleep.

scientific article published in January 1987

Alcohol exposure in utero and breast cancer risk later in life

scientific article published in May 2001

Alterations in behavior, steroid hormones and natural killer cell activity in male transgenic TGF alpha mice

scientific article published on August 14, 1992

Alterations in brain monoamines and GABAA receptors in transgenic mice overexpressing TGF alpha

scientific article published on 01 April 1995

Alterations in mammary gland development following neonatal exposure to estradiol, transforming growth factor alpha, and estrogen receptor antagonist ICI 182,780.

scientific article published in March 1997

Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling.

scientific article

Are there preexisting behavioral characteristics that predict the dominant status of male NIH Swiss mice (Mus musculus)? ⬇️

scientific article published on June 1, 1992

Attenuation of the effects of ethanol on social behavior by alpha 2-adrenoceptor antagonists

scientific article published on 01 May 1989

Author Correction: BICORN: An R package for integrative inference of de novo cis-regulatory modules

scientific article published on 07 October 2020

BICORN: An R package for integrative inference of de novo cis-regulatory modules

scientific article published on 14 May 2020

BMRF-MI: integrative identification of protein interaction network by modeling the gene dependency

scientific article published on 11 June 2015

BMRF-Net: a software tool for identification of protein interaction subnetworks by a bagging Markov random field-based method.

scientific article published on 8 March 2015

BSSV: Bayesian based somatic structural variation identification with whole genome DNA-seq data

scientific article

Behavior of alcohol-preferring AA and alcohol-avoiding ANA rat lines in tests of anxiety and aggression

scientific article published in July 1990

Behavior of streptozotocin-diabetic mice in tests of exploration, locomotion, anxiety, depression and aggression

scientific article published in September 1990

Behavioral, hormonal and neurochemical characteristics of aggressive alpha-mice

scientific article published on 01 November 1989

Binding of serotonergic ligands to brain membranes of alcohol-preferring AA and alcohol-avoiding ANA rats

scientific article published on September 1, 1992

Birth weight in relation to endometrial and breast cancer risks in Swedish women

scientific article published on 5 December 2006

Breast cancer risk in rats fed a diet high in n-6 polyunsaturated fatty acids during pregnancy

scientific article published on 01 December 1996

Breast cancer: dietary and environmental oestrogens

scientific article

CRNET: An efficient sampling approach to infer functional regulatory networks by integrating large-scale ChIP-seq and time-course RNA-seq data.

scientific article published on 21 December 2017

Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland.

scientific article

ChIP-GSM: Inferring active transcription factor modules to predict functional regulatory elements

scientific article published on 22 July 2021

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats ⬇️

scientific article published on October 16, 2010

Changes in mammary caveolin-1 signaling pathways are associated with breast cancer risk in rats exposed to estradiol in utero or during prepuberty

scientific article published on June 2010

Cognitive impairments at two years of age after prenatal alcohol exposure or perinatal asphyxia

scientific article published on 01 April 1994

Consumption of a high-fat diet alters estrogen receptor content, protein kinase C activity, and mammary gland morphology in virgin and pregnant mice and female offspring ⬇️

scientific article published on February 15, 1998

Correction to: Dietary intake of soy and cruciferous vegetables and treatment-related symptoms in Chinese-American and non-Hispanic White breast cancer survivors.

scientific article

Correlations between behavior of mice in Porsolt's swim test and in tests of anxiety, locomotion, and exploration

scientific article published in March 1990

CyNetSVM: A Cytoscape App for Cancer Biomarker Identification Using Network Constrained Support Vector Machines.

scientific article

DDN: a caBIG® analytical tool for differential network analysis

scientific article

DM-BLD: differential methylation detection using a hierarchical Bayesian model exploiting local dependency.

scientific article published on 11 September 2016

DMBA-induced mammary tumor growth in rats exhibiting increased or decreased ability to cope with stress due to early postnatal handling or antidepressant treatment.

scientific article published in August 1993

Developmental Origins of Breast Cancer: A Paternal Perspective

scientific article published in January 2018

Dietary Vitamin D Exposure Prevents Obesity-Induced Increase in Endometrial Cancer inPten+/−Mice ⬇️

scientific article published on September 21, 2010

Dietary fat and breast cancer risk in the Swedish women's lifestyle and health cohort

scientific article published on 16 October 2007

Dietary fat intake and gestational weight gain in relation to estradiol and progesterone plasma levels during pregnancy: a longitudinal study in Swedish women

scientific article

Dietary intake of soy and cruciferous vegetables and treatment-related symptoms in Chinese-American and non-Hispanic White breast cancer survivors.

scientific article published on 11 December 2017

Dietary modulation of pregnancy estrogen levels and breast cancer risk among female rat offspring

scientific article published in November 2002

Dietary n-3 polyunsaturated fatty acids fail to reduce prostate tumorigenesis in the PB-ErbB-2 x Pten(+/-) preclinical mouse model

scientific article published on 15 May 2010

Differences in the sleep-wake patterns of the AA and ANA rat lines developed for high and low alcohol intake

scientific article published in January 1986

Differentiation of mammary gland as a mechanism to reduce breast cancer risk

scientific article published on 01 October 2006

Do estrogens always increase breast cancer risk?

scientific article

Early Postnatal Treatment With Transforming Growth Factor α Does Not Alter Nonreproductive Behavior ⬇️

scientific article published on July 1, 1997

Early intake appears to be the key to the proposed protective effects of soy intake against breast cancer

scientific article published in January 2009

Early life affects the risk of developing breast cancer

scientific article published on 01 September 1995

Early postnatal deprivation of active sleep with desipramine or zimeldine impairs later behavioural reactivity to auditory stimuli in rats

scientific article published in February 1988

Early postnatal treatment with propranolol affects development of brain amines and behavior

scientific article published in January 1988

Effect of alcohol on elevated aggressive behavior in male transgenic TGF alpha mice

scientific article published on 01 February 1993

Effect of beta-casomorphin on neonatal sleep in rats

scientific article published in January 1990

Effect of dietary intervention on serum lignan levels in pregnant women - a controlled trial

scientific article

Effect of ethanol on the social behavior of group-housed and isolated mice

scientific article published on 01 October 1989

Effect of isolation on brain monoamines and the behavior of mice in tests of exploration, locomotion, anxiety and behavioral 'despair'.

scientific article published in June 1989

Effect of low alcohol dose on behavioral "despair" in rats neonatally treated with antidepressant drugs

scientific article published on 01 March 1989

Effect of neonatal clomipramine treatment on adult alcohol drinking in the AA and ANA rat lines

scientific article published on May 1986

Effect of neonatal nomifensine exposure on adult behavior and brain monoamines in rats

scientific article published on 01 January 1987

Effect of peripheral administration of arginine vasotocin on neonatal sleep in rats ⬇️

scientific article published on May 1, 1988

Effect of prenatal alcohol exposure on neonatal sleep-wake behaviour and adult alcohol consumption in the AA and ANA rat lines

scientific article published in January 1987

Effect of tryptophan on the behavior of nonstressed and stressed mice in Porsolt's swim test

scientific article published on 01 October 1990

Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model.

scientific article published on 8 September 2016

Effects of Jaeumkanghwa-tang on tamoxifen responsiveness in preclinical ER+ breast cancer model

scientific article published on 01 March 2019

Effects of Maternal Exposure to Cow's Milk High or Low in Isoflavones on Carcinogen-Induced Mammary Tumorigenesis among Rat Offspring ⬇️

scientific article published on April 5, 2011

Effects of Maternal Grape Juice Intake on Unfolded Protein Response in the Mammary Glands of Offspring of High Fat Diet Fed Rat Dams

scientific article published on 28 July 2020

Effects of Tryptophan on Depression and Aggression in STZ-D Mice ⬇️

scientific article published on December 1, 1991

Effects of caffeine on social behavior, exploration and locomotor activity: interactions with ethanol.

scientific article published in January 1989

Effects of early postnatal handling on brain β-adrenoceptors and behavior in tests related to stress ⬇️

scientific article published on March 1, 1991

Effects of ethanol on fight- or swim-stressed mice in Porsolt's swim test

scientific article published on 01 December 1989

Effects of maternal dietary exposure to cadmium during pregnancy on mammary cancer risk among female offspring

scientific article published on 29 June 2013

Effects of neonatal treatment with clomipramine on adult ethanol related behavior in the rat.

scientific article published in July 1984

Effects of pre-pregnancy physical activity and maternal BMI on gestational weight gain and birth weight

scientific article published on January 2008

Effects of prenatal alcohol exposure on neonatal sleep-wake behaviour and adult alcohol consumption in rats

scientific article published in July 1986

Effects of tryptophan and serotonin uptake inhibitors on behavior in male transgenic transforming growth factor alpha mice

scientific article published in June 1993

Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer

scientific article published on October 2016

Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer

scientific article published on March 2011

Estrogen-regulated non-reproductive behaviors and breast cancer risk: Animal models and human studies ⬇️

scientific article published on November 1, 1997

Estrogens, BRCA1, and breast cancer

scientific article

Estrogens, phytoestrogens, and breast cancer

scientific article published on January 1996

Excessive weight gain during pregnancy increases carcinogen-induced mammary tumorigenesis in Sprague-Dawley and lean and obese Zucker rats

scientific article published on April 2006

Expedition inspiration consensus 2001

scientific article published on 01 December 2001

Exposure to excess estradiol or leptin during pregnancy increases mammary cancer risk and prevents parity-induced protective genomic changes in rats

scientific article published on 29 October 2013

Exposure to lard-based high-fat diet during fetal and lactation periods modifies breast cancer susceptibility in adulthood in rats.

scientific article published on 12 March 2014

Exposures to synthetic estrogens at different times during the life, and their effect on breast cancer risk

scientific article published on 8 February 2013

Fetal origins of breast cancer

scientific article published on 25 September 2006

Gene signaling pathways mediating the opposite effects of prepubertal low-fat and high-fat n-3 polyunsaturated fatty acid diets on mammary cancer risk.

scientific article published on December 2008

Genistein: does it prevent or promote breast cancer?

scientific article

Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness

scientific article published on July 2012

Glutamine metabolism and the unfolded protein response in MYC-driven breast cancer

scientific article published on 28 May 2014

Gonadal hormones and aggression-maintaining effect of alcohol in male transgenic transforming growth factor-alpha mice.

scientific article published in June 1995

High birth weight increases mammary tumorigenesis in rats

scientific article published in October 2006

High maternal intake of polyunsaturated fatty acids during pregnancy in mice alters offsprings' aggressive behavior, immobility in the swim test, locomotor activity and brain protein kinase C activity

scientific article published in December 1998

High-fat diet induces aggressive behavior in male mice and rats

scientific article published on 01 January 1996

High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspring

scientific article published on January 2012

Hypomethylation of an exon I estrogen receptor CpG island in spontaneous and carcinogen-induced mammary tumorigenesis in the rat.

scientific article published on December 1998

In utero alcohol exposure increases mammary tumorigenesis in rats

scientific article published on June 2004

Increased adult behavioral 'despair' in rats neonatally exposed to desipramine or zimeldine: an animal model of depression?

scientific article published on November 1987

Infant feeding and the incidence of endometrial cancer

scientific article

Influence of berry polyphenols on receptor signaling and cell-death pathways: implications for breast cancer prevention

scientific article

Injection of vehicle is not a stressor in Porsolt's swim test

scientific article published on May 1, 1992

IntAPT: Integrated assembly of phenotype-specific transcripts from multiple RNA-seq profiles

scientific article published on 05 October 2020

Interaction of dietary polyphenols with molecular signaling pathways of antiestrogen resistance: possible role in breast cancer recurrence.

scientific article

Investigation of Paternal Programming of Breast Cancer Risk in Female Offspring in Rodent Models

scientific article published in January 2018

Is soy consumption good or bad for the breast?

scientific article

Isoflavones in soy flour diet have different effects on whole-genome expression patterns than purified isoflavone mix in human MCF-7 breast tumors in ovariectomized athymic nude mice

scientific article

Lifetime Genistein Intake Increases the Response of Mammary Tumors to Tamoxifen in Rats

scientific article published in February 2017

Lipidomic fatty acid profile and global gene expression pattern in mammary gland of rats that were exposed to lard-based high fat diet during fetal and lactation periods associated to breast cancer risk in adulthood

scientific article published on 23 June 2015

Longitudinal study on birthweight and the incidence of endometrial cancer

scientific article published on 18 March 2008

MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer

scientific article

Maternal and prepubertal diet, mammary development and breast cancer risk

scientific article

Maternal dietary exposure to fiber during pregnancy and mammary tumorigenesis among rat offspring

scientific article published in November 2006

Maternal exposure to diethylstilbestrol during pregnancy and increased breast cancer risk in daughters

scientific article

Maternal exposure to genistein during pregnancy increases carcinogen-induced mammary tumorigenesis in female rat offspring.

scientific article

Maternal flaxseed diet during pregnancy or lactation increases female rat offspring's susceptibility to carcinogen-induced mammary tumorigenesis

scientific article published on 22 February 2007

Maternal genistein exposure mimics the effects of estrogen on mammary gland development in female mouse offspring.

scientific article published in May 1998

Maternal handling during pregnancy reduces DMBA-induced mammary tumorigenesis among female offspring ⬇️

scientific article published on January 1, 1997

Maternal high n-6 polyunsaturated fatty acid intake during pregnancy increases voluntary alcohol intake and hypothalamic estrogen receptor alpha and beta levels among female offspring

scientific article published in September 2000

Maternal intake of high n-6 polyunsaturated fatty acid diet during pregnancy causes transgenerational increase in mammary cancer risk in mice

scientific article

Maternal obesity increases offspring's mammary cancer recurrence and impairs tumor immune response

scientific article published on 01 June 2020

Mechanisms by which high maternal fat intake during pregnancy increases breast cancer risk in female rodent offspring ⬇️

scientific article published on November 1, 1997

Mechanisms mediating the effects of prepubertal (n-3) polyunsaturated fatty acid diet on breast cancer risk in rats.

scientific article

Mental development of 2-year-old children exposed to alcohol in utero

scientific article published on May 1, 1992

Meta-analysis of soy intake and breast cancer risk.

scientific article

Molecular mechanisms of tamoxifen-associated endometrial cancer (Review).

scientific article

Neonatal antidepressant administration suppresses concurrent active (REM) sleep and increases adult alcohol consumption in rats

scientific article published in January 1987

Neonatal desipramine or zimeldine treatment causes long-lasting changes in brain monoaminergic systems and alcohol related behavior in rats

scientific article published in January 1987

Neonatal treatment with monoamine uptake inhibitors alters later response in behavioural 'despair' test to beta and GABA-B receptor agonists

scientific article published on 01 July 1988

Nutritional modulation of terminal end buds: its relevance to breast cancer prevention

scientific article published on August 2007

Nutritional modulation of the cell cycle and breast cancer.

scientific article

Opposing behavioural alterations in male and female transgenic TGF alpha mice: association with tumour susceptibility

scientific article

Opposing effects of prepubertal low- and high-fat n-3 polyunsaturated fatty acid diets on rat mammary tumorigenesis

scientific article published on 11 May 2005

Overexpression of transforming growth factor alpha in transgenic mice alters nonreproductive, sex-related behavioral differences: interaction with gonadal hormones

scientific article published in April 1994

PSSV: a novel pattern-based probabilistic approach for somatic structural variation identification.

scientific article

Paternal overweight is associated with increased breast cancer risk in daughters in a mouse model

scientific article published on 24 June 2016

Paternal programming of breast cancer risk in daughters in a rat model: opposing effects of animal- and plant-based high-fat diets

scientific article published on 26 July 2016

Perinatal factors increase breast cancer risk.

scientific article published on January 1994

Point-counterpoint: soy intake for breast cancer patients

scientific article published on March 2002

Pregnancy and lifestyle: short- and long-term effects on mother's and her children's health

scientific article published on 28 May 2013

Pregnancy hormonal environment and mother's breast cancer risk

scientific article

Pregnancy weight gain and breast cancer risk

scientific article

Pregnancy weight gain and premenopausal breast cancer risk.

scientific article published in November 2005

Prepubertal estradiol and genistein exposures up-regulate BRCA1 mRNA and reduce mammary tumorigenesis

scientific journal article

Prepubertal exposure to cow's milk reduces susceptibility to carcinogen-induced mammary tumorigenesis in rats

scientific article

Prepubertal exposure to zearalenone or genistein reduces mammary tumorigenesis

scientific article

Prepubertal physical activity up-regulates estrogen receptor beta, BRCA1 and p53 mRNA expression in the rat mammary gland

scientific journal article

Preventing excessive weight gain during pregnancy - a controlled trial in primary health care

scientific article published on 17 January 2007

Protective Effects of Prepubertal Genistein Exposure on Mammary Tumorigenesis Are Dependent on BRCA1 Expression ⬇️

scientific article published on June 16, 2011

Psychosocial factors and breast cancer

scientific article published on 01 January 1992

Psychosocial factors in the development and progression of breast cancer.

scientific article published on February 1994

RO 15-4513 and FG 7142 reverse the reduction in social behavior caused by ethanol in mice

scientific article published on 01 September 1988

Reversal of increased mammary tumorigenesis by valproic acid and hydralazine in offspring of dams fed high fat diet during pregnancy

scientific article published on 30 December 2019

Revitalization of the AA and ANA rat lines: effects on some line characteristics

scientific article published in January 1984

Richard G. Lister: friend, colleague and teacher ⬇️

scientific article published on 01 January 1991

Role of estradiol in alcohol intake and alcohol-related behaviors.

scientific article published in March 1996

Serum Estradiol Levels and Ethanol-Induced Aggression ⬇️

scientific article published on 01 November 1997

Sleep-wake behavior of newborn rats recorded with movement sensitive method

scientific article published in March 1986

Sleeping and dreams in learning-disabled boys

scientific article published in July 1987

Social isolation induces autophagy in the mouse mammary gland: link to increased mammary cancer risk.

scientific article published on 22 August 2016

Social status and voluntary alcohol consumption in mice: interaction with stress

scientific article published in January 1992

SparseIso: A novel Bayesian approach to identify alternatively spliced isoforms from RNA-seq data

scientific article published on 4 September 2017

Steroid And Thyroid Hormone Concentrations In Pregnant And Non-pregnant Women Using Isotope Dilution Tandem Mass Spectrometry

Steroid hormone levels in pregnancy and 1 year postpartum using isotope dilution tandem mass spectrometry

scientific article

Stress influence on development of hepatocellular tumors in transgenic mice overexpressing TGF alpha

scientific article published on 01 January 1995

Tallness and overweight during childhood have opposing effects on breast cancer risk

scientific article published on November 2001

The effects of novelty, isolation, light and ethanol on the social behavior of mice

scientific article published in January 1988

The influence of maternal diet on breast cancer risk among female offspring

scientific article

The role of early life genistein exposures in modifying breast cancer risk

scientific article published on 8 April 2008

Timing of dietary estrogenic exposures and breast cancer risk

scientific article

Timing of dietary fat exposure and mammary tumorigenesis: role of estrogen receptor and protein kinase C activity

scientific article published on 01 November 1998

Trimester-specific reference intervals for thyroxine and triiodothyronine in pregnancy in iodine-sufficient women using isotope dilution tandem mass spectrometry and immunoassays

scientific article published on November 2004

Use of ERE and reporter gene constructs to assess putative estrogenic activity.

scientific article published on January 1999

[Aging and sleep]

scientific article published on 01 January 1985

[Minimal brain dysfunction--neurobiological approach]

scientific article published on 01 January 1986

mAPC-GibbsOS: an integrated approach for robust identification of gene regulatory networks.

scientific article

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